A use of corticoids in the treatment of Alopecia Areata

Authors

DOI:

https://doi.org/10.33448/rsd-v12i5.41411

Keywords:

Alopecia Areata; Corticosteroids; Benefits; Side effects.

Abstract

Alopecia Areata (AA) is a pathology that affects the follicular unit and nail changes concomitantly with the condition, with an undefined and multifactorial cause and evident autoimmune and genetic manifestations. Therefore, the objective is to evaluate the use of corticosteroids in the treatment of Alopecia Arreata. This is a methodical literature review, with the proposal to carry out a search for scientific articles through electronic research, based on the data listed: SCIELO (Online Scientific Electronic Library) Lilacs (Latin American and Caribbean Literature in Health Sciences), Bireme (Latin American and Caribbean Center on Health Sciences Information), Pubmed (Search platform of the National Library of Medicine), between the years 2010 to 2022. In the results, the safety and efficacy of corticosteroids for patients affected by AA proved to be responsive and safe. In the selected studies, it was understood that this drug has as a mechanism of action there is the stimulation of hair folic acid, thus increasing the duration of its anagen phase.

References

AAGAP. (2022). O que é alopecia areata? Grupo de apoio aos pacientes com alopecia areata (AAGAP). https://www.sbd-sp.org.br/geral/aagap_/.

Askın, O. et al. (2021). Evaluation of the level of serum Interleukins (IL-2, IL-4, IL-15 andIL-17) and its relationship with disease severity in patients with alopecia areata. Anais Brasileiros de Dermatologia. 96(5): 551-7.

Barton, V. R. (2022). Treatment of pediatric alopecia areata: A systematic review. Am Acad Dermatol. 86(6): 1318–34.

Chanprapaph, K. (2022). Intramuscular Corticosteroid Therapy in the Treatment of Alopecia Areata: A Time-to-Event Analysis. Drug Design, Development and Therapy. 16, 107–16.

Craveiro, A. P. C. (2017). Alopecia Areata Comorbilidades e limitações terapêuticas. Dissertação para obtenção do Grau de Mestre em Medicina. Covilhã, março de 2017.

Cranwell, W. C. et al. (2018). Treatment of alopecia areata: An Australian expert consensus statement. Australasian Journal of Dermatology.56(2) 1214-45.

Fernando, T.; Goldman, R.D. (2020). Corticosteroids for alopecia areata in children. July Juillet. 66(8).56-62.

Formiga, M. W. M., Sousa, M. N. A. de, & Egypto, L. V. do . (2021). Comparative study of the effectiveness of treatments for androgenetic alopecia through the capillary intradermotherapy technique: minoxidil and finasteride. Research, Society and Development, 10(10), e251101018832. https://doi.org/10.33448/rsd-v10i10.18832

Fridman, M.; Ray, M.; Gandhi, k. (2022). Treatment Patterns and Treatment Satisfaction Among Adults with Alopecia Areata in the United States. Adv Ther (2022) 39:5504–5513.

Hordinsky, M. (2021). Alopecia areata. J Am Acad Dermatol. 2021 Jan; 78(1):1-12.

Jerry S. (2020). Current Treatment of Alopecia Areata. Journal of Investigative Dermatology Symposium Proceedings. 20(7) 145-150

Macedo, J. L., Oliveira, A. S. da S. S., Pereira, I. C., Assunção, F. D., Reis, E. R., & Assunção, M. de J. S. M. (2019). Efficacy of phytotherapy in the treatment of androgenetic alopecia. Research, Society and Development, 8(5), e285868. https://doi.org/10.33448/rsd-v8i5.868

Mazucato, T. (Org.). (2018). Metodologia da pesquisa e do trabalho científico. Penápolis: funepe, 2018.

Melo, D.F. et al. (2018). Intralesional betamethasone as a therapeutic option for alopecia areata. An Bras Dermatol. 2018;93(2):304-12.

Pereira, A. S. (2018). Metodologia da pesquisa científica. Santa Maria, RS: UFSM, 2018.

Ramos, P. M. et al. (2020). Consenso sobre tratamento da alopecia areata −Sociedade Brasileira de Dermatologia. Anais Brasileiros de Dermatologia 2020;95(S1):3952.

Robinson, A. R. (2018). Pathology and Treatment of Alopecia Areata (Classic Reprint). New York: Forgotten Books. 2018, 38 p.

Sousa, B. M. da S., Natal, T. J., Pereira, T. B., Drummond, M. V. M. S., & Neves, R. A. (2021). Comparative analysis between treatments for alopecia: a systematic review. Research, Society and Development, 10(15), e134101522770. https://doi.org/10.33448/rsd-v10i15.22770

Young B. L., Won-Soo L. (2021). Efficacy of antihistamines in combination with topical corticosteroid and superficial cryotherapy for treatment of alopecia areata: A retrospective cohort study. Research letter. 84(7), ISSUE 4, P1152-1154, April 2021.

Yaee B. et al. (2020). Efficacy of different concentrations of intralesional triamcinolone acetonide for alopecia areata: A systematic review and meta-analysis. J Am Acad Dermatol. 2020 Apr;82(4):1018-1021. 10.1016/j.jaad.2019.11.066.

Published

26/04/2023

How to Cite

LIMA, C. O. .; COSTA , E. S. .; FRANCO , J. V. V. .; BRAZ, D. C. .; CAMPOS, L. S. .; CAL, G. G. V. .; CAVALCANTE , A. C. N. . A use of corticoids in the treatment of Alopecia Areata. Research, Society and Development, [S. l.], v. 12, n. 5, p. e2712541411, 2023. DOI: 10.33448/rsd-v12i5.41411. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/41411. Acesso em: 27 apr. 2024.

Issue

Section

Review Article