Clinical and epidemiological profile of patients hospitalized in a COVID-19 Maternal

Authors

DOI:

https://doi.org/10.33448/rsd-v12i6.42295

Keywords:

Sars-CoV-2; COVID-19; Pregnancy.

Abstract

Objective: to trace the clinical and epidemiological profile of pregnant women and internal puerperal women in a COVID-19 intensive care unit in a high complexity maternity hospital in the city of Teresina-PI. Methods: this is a quantitative, descriptive, retrospective study of medical records review conducted in a maternity hospital located in the city of Teresina-PI. Medical records of pregnant women with clinical or serological diagnosis of COVID-19 were included. Medical records with many incomplete data (above 20), patients without a diagnosis of COVID-19 and symptoms appeared after delivery were excluded. Results: The total sample of this study consisted of 43 medical records of patients who met the established criteria, most of them women aged 18 to 30 years (60.4%; N=26), with a weight greater than 65kg (60.4%; N=26), multi-gestas (55.8%; N=24), who performed prenatal consultations (88.3%; N=38) and presented at least one intercorrence in pregnancy (67.4%; N=29). The most reported clinical manifestations were dyspnea (95.3%; N=42) and cough (81.3%; N=35). In addition, the research reveals a high rate of preterm delivery (80%; N=20) and cesarean (100%; N=25). 69.7% (N=30) of the sample required ventilatory support. It is necessary to conduct further studies to understand the true profile of this public and understand the other consequences that the disease brings to pregnant women.

References

Abedzadeh-Kalahroudi, M., Sehat, M., Vahedpour, Z., Talebian, P., & Haghighi, A. (2021). Clinical and obstetric characteristics of pregnant women with Covid-19: A case series study on 26 patients. Taiwanese Journal of Obstetrics and Gynecology, 60(3), 458–462. https://doi.org/10.1016/j.tjog.2021.03.012

Abu-Raya, B. (2020). Predictors of refractory Coronavirus disease (COVID-19) pneumonia. Clinical Infectious Diseases. https://doi.org/10.1093/cid/ciaa409

Ahumada-Barrios, M. E., & Alvarado, G. F. (2016). Risk Factors for premature birth in a hospital 1. Revista Latino-Americana de Enfermagem, 24. https://doi.org/10.1590/1518-8345.0775.2750

Alves, I. S. G., Santos, A. A. P. dos, Sanches, M. E. T. de L., Maraysa Jéssyca de Oliveira Vieira, M. J. D. O., Texeira, L. D. M., & Costa, A. V. (2021). Premature delivery work: associated conditions. Revista de Enfermagem UFPE on Line, 15(1). https://doi.org/10.5205/1981-8963.2021.245860

Antoun, L., Taweel, N. E., Ahmed, I., Patni, S., & Honest, H. (2020). Maternal COVID-19 infection, clinical characteristics, pregnancy, and neonatal outcome: A prospective cohort study. European Journal of Obstetrics & Gynecology and Reproductive Biology, 252, 559–562. https://doi.org/10.1016/j.ejogrb.2020.07.008

Badr, D. A., Mattern, J., Carlin, A., Cordier, A.-G., Maillart, E., Hachem, L. E., Kenz, H. E., Andronikof, M., Bels, D. D., Damoisel, C., Preseau, T., Vignes, D., Cannie, M. M., Vauloup-Fellous, C., Fils, J.-F., Benachi, A., Jani, J. C., & Vivanti, A. J. (2020). Are clinical outcomes worse for pregnant women at ≥20 weeks’ gestation infected with coronavirus disease 2019? A multicenter case-control study with propensity score matching. American Journal of Obstetrics & Gynecology, 223(5), 764–768. https://doi.org/10.1016/j.ajog.2020.07.045

Brasil (2020). Manual de Recomendações para a Assistência À Gestante e Puérpera frenteà Pandemia de Covid-19. https://bvsms.saude.gov.br/bvs/publicacoes/manual_assistencia_gestante_puerpera_covid19_2ed.pdf

Brasil. (2020a). Protocolo de Manejo Clínico da Covid-19 na Atenção Especializada. https://covid.saude.gov.br/

Brasil. (2020b). Atenção à saúde do recém-nascido no contexto da infecção pelo novo coronavírus. Nota Técnica Nº 6/2020 COCAM/CGCIVI/DAPES/SAPS/MS. https://covid.saude.gov.br/

Breslin, N., Baptiste, C., Gyamfi-Bannerman, C., Miller, R., Martinez, R., Bernstein, K., Ring, L., Landau, R., Purisch, S., Friedman, A. M., Fuchs, K., Sutton, D., Andrikopoulou, M., Rupley, D., Sheen, J.-J., Aubey, J., Zork, N., Moroz, L., Mourad, M., & Wapner, R. (2020). Coronavirus disease 2019 infection among asymptomatic and symptomatic pregnant women: two weeks of confirmed presentations to an affiliated pair of New York City hospitals. American Journal of Obstetrics & Gynecology Mfm. https://doi.org/10.1016/j.ajogmf.2020.100118

Caussy, C., Wallet, F., Laville, M., & Disse, E. (2020). Obesity is associated with severe forms of COVID‐19. Obesity. https://doi.org/10.1002/oby.22842

Cavalcante, A. N. M., Tavares, L. V. de S., Bastos, M. L. A., & Almeida, R. L. F. de. (2021). Clinical-epidemiological profile of children and adolescents with COVID-19 in Ceará. Revista Brasileira de Saúde Materno Infantil, 21(suppl 2), 429–435. https://doi.org/10.1590/1806-9304202100s200006

Chen, Y., Peng, H., Wang, L., Zhao, Y., Zeng, L., Gao, H., & Liu, Y. (2020). Infants Born to Mothers With a New Coronavirus (COVID-19). Frontiers in Pediatrics, 8. https://doi.org/10.3389/fped.2020.00104

D’Souza, R., Ashraf, R., Rowe, H., Zipursky, J., Clarfield, L., Maxwell, C., Arzola, C., Lapinsky, S., Paquette, K., Murthy, S., Cheng, M. P., & Malhamé, I. (2021). Pregnancy and COVID ‐19: pharmacologic considerations. Ultrasound in Obstetrics & Gynecology, 57(2), 195–203. https://doi.org/10.1002/uog.23116

Da Cruz Lima, E., Marques dos Santos, L., Cerqueira dos Santos, S., Moreira Christoffel, M., & Pereira da Costa Kerber, N. (2018). Vivências de familiares durante o trabalho de parto pré-termo. Revista Cuidarte, 10(1). https://doi.org/10.15649/cuidarte.v10i1.616

Dias, T. Z., Mariana Caramore Fava, Renato Passini Júnior, José Guilherme Cecatti, Ricardo Porto Tedesco, Lajos, G. J., Patricia Moretti Rehder, Marcelo Ayumu Nomura, Oliveira, P. F., & Costa, M. (2018). Tocolysis among Women with Preterm Birth: Associated Factors and Outcomes from a Multicenter Study in Brazil. 40(04), 171–179. https://doi.org/10.1055/s-0038-1642025

Dollinger, S., Zlatkin, R., Jacoby, C., Shmueli, A., Barbash-Hazan, S., Chen, R., Danieli, H. Z., Sukenik, S., Hadar, E., & Wiznitzer, A. (2022). Clinical Characteristics and Outcomes of COVID-19 During Pregnancy—a Retrospective Cohort Study. Reproductive Sciences. https://doi.org/10.1007/s43032-022-00949-4

Duarte, I., Neto, N., Carretero, D., Freitas, C., Vieira, A., & Guimarães, L. (2021). [ID 55280] fatores preditores maternos e neonatais relacionados à prematuridade em um município do interior de São Paulo. Revista Brasileira de Ciências Da Saúde, 25(2). https://doi.org/10.22478/ufpb.2317-6032.2021v25n2.55280

Ghafoor, H., Abdus samad, A., Bel Khair, AOM, Ahmed, O., & Khan, MNA (2022). Manejo de Cuidados Intensivos de COVID-19 Grave em Pacientes Grávidas. Cureu . https://doi.org/10.7759/cureus.24885

Huang, C., Wang, Y., Li, X., Ren, L., Zhao, J., Hu, Y., Zhang, L., Fan, G., Xu, J., Gu, X., Cheng, Z., Yu, T., Xia, J., Wei, Y., Wu, W., Xie, X., Yin, W., Li, H., Liu, M., & Xiao, Y. (2020). Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. The Lancet, 395(10223), 497–506. https://doi.org/10.1016/s0140-6736(20)30183-5

Lombardi, A., Duiella, S., Li Piani, L., Comelli, A., Ceriotti, F., Oggioni, M., Muscatello, A., Bandera, A., Gori, A., & Ferrazzi, E. (2021). Inflammatory biomarkers in pregnant women with COVID-19: a retrospective cohort study. Scientific Reports, 11(1), 13350. https://doi.org/10.1038/s41598-021-92885-7

Matar, R., Alrahmani, L., Monzer, N., Debiane, L. G., Berbari, E., Fares, J., Fitzpatrick, F., & Murad, M. H. (2020). Clinical Presentation and Outcomes of Pregnant Women With Coronavirus Disease 2019: A Systematic Review and Meta-analysis. Clinical Infectious Diseases. https://doi.org/10.1093/cid/ciaa828

Nogueira, C. M. C. de S., Alcantara, J. R. de, Costa, H. M. G. e S., Morais, F. R. R., Bezerra, K. P., & Fialho, A. V. de M. (2020). Análise nacional do perfil das gestantes acometidas pela COVID-19 / National analysis of the profile of pregnant women affected by COVID-19. Brazilian Journal of Health Review, 3(5), 14267–14278. https://doi.org/10.34119/bjhrv3n5-228

Ortiz Molina, E., Hernandez Pailos, R., Pola Guillen, M., Pascual Pedreno, A., Rodriguez Rodriguez, E., & Hernandez Martinez, A. (2020). COVID-19 infection in symptomatic pregnant women at the midpoint of the pandemic in Spain: a retrospective analysis. Ginekologia Polska, 91(12), 755–763. https://doi.org/10.5603/GP.a2020.0130

Petrilli, C. M., Jones, S. A., Yang, J., Rajagopalan, H., O’Donnell, L., Chernyak, Y., Tobin, K. A., Cerfolio, R. J., Francois, F., & Horwitz, L. I. (2020). Factors associated with hospital admission and critical illness among 5279 people with coronavirus disease 2019 in New York City: prospective cohort study. BMJ, 369. https://doi.org/10.1136/bmj.m1966

Popescu, D. E., Cioca, A., Muresan, C., Navolan, D., Gui, A., Pop, O., Marcovici, T., Ilie, C., Craina, M., & Boia, M. (2021). A Case of COVID-19 Pregnancy Complicated with Hydrops Fetalis and Intrauterine Death. Medicina, 57(7), 667. https://doi.org/10.3390/medicina57070667

Romanowski, F., Mariane, C., & Neris, N. (2019). Manual De Tipos De Estudo. Centro UniversitáRio De AnáPolis, 0–39.

Sattari, M., Bashirian, S., Masoumi, S. Z., Shayan, A., Jenabi, E., Ghelichkhani, S., Shirzadeh, A. A., Jalili, E., & Alimohammadi, S. (2020). Evaluating Clinical Course and Risk Factors of Infection and Demographic Characteristics of Pregnant Women with COVID-19 in Hamadan Province, West of Iran. Journal of Research in Health Sciences, 20(3), e00488–e00488. https://doi.org/10.34172/jrhs.2020.22

Simonnet, A., Chetboun, M., Poissy, J., Raverdy, V., Noulette, J., Duhamel, A., Labreuche, J., Mathieu, D., Pattou, F., Jourdain, M., & Lille Intensive Care COVID-19 and Obesity study group. (2020). High prevalence of obesity in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) requiring invasive mechanical ventilation. Obesity (Silver Spring, Md.), 28(7). https://doi.org/10.1002/oby.22831

Vouga, M., Favre, G., Martinez-Perez, O., Pomar, L., Acebal, L. F., Abascal-Saiz, A., Hernandez, M. R. V., Hcini, N., Lambert, V., Carles, G., Sichitiu, J., Salomon, L., Stirnemann, J., Ville, Y., de Tejada, B. M., Goncé, A., Hawkins-Villarreal, A., Castillo, K., Solsona, E. G., & Trigo, L. (2021). Maternal outcomes and risk factors for COVID-19 severity among pregnant women. Scientific Reports, 11(1), 13898. https://doi.org/10.1038/s41598-021-92357-y

Wu, X., Sun, R., Chen, J., Xie, Y., Zhang, S., & Wang, X. (2020). Radiological findings and clinical characteristics of pregnant women with COVID-19 pneumonia. International Journal of Gynecology & Obstetrics. https://doi.org/10.1002/ijgo.13165

Yan, J., Guo, J., Fan, C., Juan, J., Yu, X., Li, J., Feng, L., Li, C., Chen, H., Qiao, Y., Lei, D., Wang, C., Xiong, G., Xiao, F., He, W., Pang, Q., Hu, X., Wang, S., Chen, D., & Zhang, Y. (2020). Coronavirus disease 2019 (COVID-19) in pregnant women: A report based on 116 cases. American Journal of Obstetrics and Gynecology, 223(1), 111.e1–111.e14. https://doi.org/10.1016/j.ajog.2020.04.014

Published

03/07/2023

How to Cite

EVANGELISTA, B. O. .; OLIVEIRA, B. S. A. de .; ALVES , M. D. S. .; BARROS, A. M. N. .; SOUSA, L. G. L. F. .; CORREIA , D. E. L. .; LOIOLA, K. C. da C. . Clinical and epidemiological profile of patients hospitalized in a COVID-19 Maternal . Research, Society and Development, [S. l.], v. 12, n. 6, p. e29012642295, 2023. DOI: 10.33448/rsd-v12i6.42295. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/42295. Acesso em: 4 may. 2024.

Issue

Section

Health Sciences