Analysis of patients with severe acute respiratory syndrome belonging to a municipality in the south of Santa Catarina in the period from 2019 to 2022

Authors

DOI:

https://doi.org/10.33448/rsd-v12i8.42812

Keywords:

SARS-CoV-2; Severe Acute Respiratory Syndrome; Prevalence.

Abstract

Objectives: To understand the profile of patients with severe acute respiratory syndrome in the municipality of Tubarão, Santa Catarina. Methods: A cross-sectional study was conducted, analyzing data from notifications and investigations of 3.295 severe acute respiratory syndrome cases, with data recorded and reported to the Notifiable Diseases Information System (SINAN), from january 2019 to june 2022. Results: Among the signs and symptoms presented by the patients, the most common were: Dyspnea (86.9%), Respiratory Distress (85.0%), and Oxygen Saturation < 95% (64,7%). Approximately 29.5% of patients were admitted to the ICU, and 48.4% received invasive ventilatory support. The most commonly associated comorbidity with the syndrome was Chronic Cardiovascular Disease, present in 44.2% of patients. Additionally, around 36% of patients progressed to death. Conclusion: Severe Acute Respiratory Syndrome is a condition with high mortality and a need for ventilatory support, invasive or non-invasive. It is significantly associated with the most prevalent comorbidities in the population, such as Diabetes Mellitus and Chronic Cardiovascular Disease. Therefore, research in these areas is crucial to encourage prevention and treatment measures, thereby reducing the costs associated with public health.

References

Baratella1, E., Crivelli2, P., Marrocchio3, C., Bozzato3, A. M., Vito4, A. De, Madeddu4, G., Saderi5, L., Confalonieri6, M., Tenaglia7, L., & Cova1, M. A. (2020). Severity of lung involvement on chest X-rays in SARS-coronavirus-2 infected patients as a possible tool to predict clinical progression: an observational retrospective analysis of the relationship between radiological, clinical, and laboratory data. J Bras Pneumol., 46(5), e20200226–e20200226. https://www.jornaldepneumologia.com.br/how-to-cite/3418/pt-BR

Booth, C. M. (2003). Clinical Features and Short-term Outcomes of 144 Patients With SARS in the Greater Toronto Area. JAMA, 289(21), 2801. https://doi.org/10.1001/jama.289.21.JOC30885

Cárdenas-Jaén, K., Sánchez-Luna, S. A., Vaillo-Rocamora, A., Castro-Zocchi, M. R., Guberna-Blanco, L., Useros-Brañas, D., Remes-Troche, J. M., Ramos-De la Medina, A., Priego-Parra, B. A., Velarde-Ruiz Velasco, J. A., Martínez-Ayala, P., Urzúa, Á., Guiñez-Francois, D., Pawlak, K. M., Kozłowska-Petriczko, K., Gorroño-Zamalloa, I., Urteaga-Casares, C., Ortiz-Polo, I., del Val Antoñana, A., & de-Madaria, E. (2022). Gastrointestinal symptoms and complications in patients hospitalized due to COVID-19, an international multicentre prospective cohort study (TIVURON project). Gastroenterología y Hepatología. https://doi.org/10.1016/j.gastrohep.2022.10.007

Carraro, Í., Bianca, B. Pereira2, A. B., Célia, M., & Ciaccia3, C. (2021). Sintomatologia, radiografia e evolução dos casos de SRAG por VRS e SARS-Cov-2 no Brasil, no primeiro trimestre de 2021. Revista Científica Integrada, 5(2). https://www.unaerp.br/revista-cientifica-integrada/edicoes-anteriores/volume-5-edicao-2/4441-sintomatologia-radiografia-e-evolucao-dos-casos-de-srag-por-vrs-e-sars-cov-2-no-brasil-no-primeiro-trimestre-de-2021/file

Coleman, B. L., Fadel, S. A., Fitzpatrick, T., & Thomas, S. M. (2018). Risk factors for serious outcomes associated with influenza illness in high- versus low- and middle-income countries: Systematic literature review and meta-analysis. Influenza and Other Respiratory Viruses, 12(1), 22–29. https://doi.org/10.1111/IRV.12504

Custódio, A. C. D., Ribas, F. V., Toledo, L. V., Carvalho, C. J. de, Lima, L. M., & Freitas, B. A. C. de. (2021). Hospitalizations and mortality by severe acute respiratory syndrome: comparison between the pre-pandemic and pandemic periods. Revista Brasileira de Epidemiologia, 24. https://doi.org/10.1590/1980-549720210052

de Araujo, K. L. R., de Aquino, É. C., da Silva, L. L. S., & Ternes, Y. M. F. (2020). Fatores associados à Síndrome Respiratória Aguda Grave em uma Região Central do Brasil. Ciência & Saúde Coletiva, 25, 4121–4130. https://doi.org/10.1590/1413-812320202510.2.26802020

Forchette, L., Sebastian, W., & Liu, T. (2021). A Comprehensive Review of COVID-19 Virology, Vaccines, Variants, and Therapeutics. Current Medical Science, 41(6), 1037–1051. https://doi.org/10.1007/s11596-021-2395-1

Harrison, S. L., Fazio-Eynullayeva, E., Lane, D. A., Underhill, P., & Lip, G. Y. H. (2020). Comorbidities associated with mortality in 31,461 adults with COVID-19 in the United States: A federated electronic medical record analysis. PLOS Medicine, 17(9), e1003321. https://doi.org/10.1371/journal.pmed.1003321

Hochman, B., Nahas, F. X., Oliveira Filho, R. S. de, & Ferreira, L. M. (2005). Desenhos de pesquisa. Acta Cirurgica Brasileira, 20(suppl 2), 2–9. https://doi.org/10.1590/S0102-86502005000800002

Jacek, C., Karolina, S., Orzeł, A., Frączek, M., & Tomasz, Z. (2021). Comparison of the clinical differences between COVID-19, SARS, influenza, and the common cold: A systematic literature review. Advances in Clinical and Experimental Medicine, 30(1), 109–114. https://doi.org/10.17219/acem/129573

Lai, C.-C., Shih, T.-P., Ko, W.-C., Tang, H.-J., & Hsueh, P.-R. (2020). Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges. International Journal of Antimicrobial Agents, 55(3), 105924. https://doi.org/10.1016/j.ijantimicag.2020.105924

Li, X., Zhong, X., Wang, Y., Zeng, X., Luo, T., & Liu, Q. (2021). Clinical determinants of the severity of COVID-19: A systematic review and meta-analysis. PLOS ONE, 16(5), e0250602. https://doi.org/10.1371/journal.pone.0250602

Majumder, J., & Minko, T. (2021). Recent Developments on Therapeutic and Diagnostic Approaches for COVID-19. The AAPS journal, 23(1). https://doi.org/10.1208/S12248-020-00532-2

MINISTÉRIO DA SAÚDE. Secretaria de Vigilância em Saúde. (2021). 92o Boletim Epidemiológico Especial: Doença pelo Coronavírus - COVID-19.

Ministério da Saúde Secretaria de Vigilância em Saúde Coordenação-Geral de Desenvolvimento da Epidemiologia em Serviços, B. (2019). Guia de Vigilância em Saúde : volume único [recurso eletrônico]. http://bvsms.saude.gov.br/bvs/publicacoes/guia_vigilancia_saude_3ed.pdf

Niquini, R. P., Lana, R. M., Pacheco, A. G., Cruz, O. G., Coelho, F. C., Carvalho, L. M., Villela, D. A. M., da Costa Gomes, M. F., & Bastos, L. S. (2020). SRAG por COVID-19 no Brasil: descrição e comparação de características demográficas e comorbidades com SRAG por influenza e com a população geral. Cadernos de Saúde Pública, 36(7), e00149420. https://doi.org/10.1590/0102-311X00149420

Peyrony, O., Marbeuf-Gueye, C., Truong, V., Giroud, M., Rivière, C., Khenissi, K., Legay, L., Simonetta, M., Elezi, A., Principe, A., Taboulet, P., Ogereau, C., Tourdjman, M., Ellouze, S., & Fontaine, J.-P. (2020). Accuracy of Emergency Department Clinical Findings for Diagnosis of Coronavirus Disease 2019. Annals of Emergency Medicine, 76(4), 405–412. https://doi.org/10.1016/j.annemergmed.2020.05.022

Ribas, F. V., Custódio, A. C. D., Toledo, L. V., Henriques, B. D., Sediyama, C. M. N. de O., & Freitas, B. A. C. de. (2022). Completude das notificações de síndrome respiratória aguda grave no âmbito nacional e em uma regional de saúde de Minas Gerais, durante a pandemia de COVID-19, 2020. Epidemiologia e Serviços de Saúde, 31(2). https://doi.org/10.1590/s1679-49742022000200004

Sansone, N. M. S., Boschiero, M. N., & Marson, F. A. L. (2022). Epidemiologic Profile of Severe Acute Respiratory Infection in Brazil During the COVID-19 Pandemic: An Epidemiological Study. Frontiers in Microbiology, 13. https://doi.org/10.3389/fmicb.2022.911036

Secretaria de Atenção Primária à Saúde (SAPS). (2020). Protocolo de manejo clínico do coronavírus (COVID-19) na atenção primária à saúde. 4. https://www.saude.ms.gov.br/wp-content/uploads/2020/03/Protocolo-Manejo-Clinico_APS_versao04.pdf

Silveira, M. B., Oliveira, D. de L., Silva, N. M. da, Finotti, A., Pereira, L. A., & Manrique, E. J. C. (2021). Perfil dos casos de síndrome respiratória aguda grave obtidos por um laboratório de referência em saúde pública. Research, Society and Development, 10(6), e51710616056. https://doi.org/10.33448/rsd-v10i6.16056

Siqueira, A. R., Marcon, C. E. M., & Trevisol, F. S. (2022). Perfil clínico-epidemiológico dos idosos acometidos pela COVID-19 em um município do sul de Santa Catarina. Research, Society and Development, 11(11), e502111133851. https://doi.org/10.33448/rsd-v11i11.33851

Published

09/08/2023

How to Cite

SOARES, G. K. .; GOULART, I. G. .; MARCON, C. E. M. . Analysis of patients with severe acute respiratory syndrome belonging to a municipality in the south of Santa Catarina in the period from 2019 to 2022. Research, Society and Development, [S. l.], v. 12, n. 8, p. e2812842812, 2023. DOI: 10.33448/rsd-v12i8.42812. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/42812. Acesso em: 14 nov. 2024.

Issue

Section

Health Sciences