The use of hormonal contraceptives by adolescents and possible health risks: An integrative review

Authors

DOI:

https://doi.org/10.33448/rsd-v12i10.43385

Keywords:

Adolescent; Contraceptive agents, hormonal; Health risk.

Abstract

The objective of the study was to analyze the health risks related to the use of hormonal contraceptives by the adolescent population in the literature. This is an integrative review of the literature, which included articles published and indexed in the databases National Library of Medicine (PUBMED), Medical Literature Analsis and Retrieval System On-line (MEDLINE), Latin American and Caribbean Literature in Health Sciences (LILACS), Spanish Bibliographic Index of Health Sciences (IBECS), Nursing Database (BDENF), using the descriptors: “Adolescent”; “Hormonal Contraceptives” and “Risks to human health”, published between 2018 and 2023 in all languages. Therefore, 9 articles were included, which showed that the use of contraceptives in adolescents, despite being beneficial in some situations such as such as abortion, neonatality, it is essential to assess the risk arising from use in the adolescent population, especially with regard to mental health and risks of sexually transmitted infections. The findings of this review revealed some adverse effects, particularly mood changes. However, it suggests It is necessary that new research be carried out to investigate further adverse effects of the use of these contraceptives and real impacts on the general health of adolescents.

Author Biographies

Antonia Jéssica de Oliveira Fontenele, Centro Universitário Uninovafapi

Graduanda em Enfermagem no Centro Universitário Uninovafapi

Antonia Arlene Lima, Faculdade Estácio de Teresina

Graduanda em Enfermagem na Faculdade Estácio de Teresina

Camila Santos da Silva, Centro de Ensino Unificado do Piauí

Graduanda em Enfermagem no Centro de Ensino Unificado do Piauí- CEUP

Ryan Pereira Tarquino, Centro de Ensino Unificado do Piauí

Graduando em Enfermagem no Centro de Ensino Unificado do Piauí- CEUP

Raylle Tauanny Alves Gomes, Centro de Ensino Unificado do Piauí

Graduanda em Enfermagem no Centro de Ensino Unificado do Piauí- CEUP

Maria Eduarda Damacena Silva , Faculdade Estácio de Teresina

Graduanda em Enfermagem na Faculdade Estácio de Teresina

Bruno da Silva Gomes, Centro de Ensino Unificado do Piauí

Docente no Centro de Ensino Unificado do Piauí- CEUP

References

Albuquerque, J.S, & Soares, J. (2018). Métodos anticoncepcionais reversíveis: uma revisão. [Trabalho de Conclusão de Curso-Graduação]. Universidade Federal De Campina Grande. 34-35. http://dspace.sti.ufcg.edu.br:8080/jspui/handle/riufcg/6730

Balle, C., Konstantinus, I. N., Jaumdally, S. Z., Havyarimana, E., Lennard, K., Esra, R., Barnabas, S. L., Happel, A. U., Moodie, Z., Gill, K., Pidwell, T., Karaoz, U., Brodie, E., Maseko, V., Gamieldien, H., Bosinger, S. E., Myer, L., Bekker, L. G., Passmore, J. S., & Jaspan, H. B. (2020). Hormonal contraception alters vaginal microbiota and cytokines in South African adolescents in a randomized trial. Nature communications, 11(1), 5578. https://doi.org/10.1038/s41467-020-19382-9

Barnabas, S. L., Dabee, S., Passmore, J. S., Jaspan, H. B., Lewis, D. A., Jaumdally, S. Z., Gamieldien, H., Masson, L., Muller, E., Maseko, V. D., Mkhize, N., Mbulawa, Z., Williamson, A. L., Gray, C. M., Hope, T. J., Chiodi, F., Dietrich, J., Gray, G., Bekker, L. G., & Women’s Initiative in Sexual Health (WISH) study team (2018). Converging epidemics of sexually transmitted infections and bacterial vaginosis in southern African female adolescents at risk of HIV. International journal of STD & AIDS, 29(6), 531–539. https://doi.org/10.1177/0956462417740487

Brandt, G. P., Oliveira, A. P. R. D., & Burci, L. M. (2018). Anticoncepcionais hormonais na atualidade: um novo paradigma para o planejamento familiar. Revista Gestão & Saúde, 18(1), 54-62. https://www.herrero.com.br/site/files/revista/fileffb43b6252282b433e193bacf91d43f7.pdf

Brasil. Ministério da Saúde. (2013). Boletim Epidemiológico – HIV e Aids. Ano II - nº 1 - até semana epidemiológica 26ª. Brasília.

Brasil. (1990). Estatuto da Criança e do Adolescente. Lei nº 8.069 de 13 de julho de 1990. Brasília, DF.

Caldeirão, T. D., Orsolini, L. R., da Silva, C. C., Bisi Rizzo, A. D. C., Teixeira, A. S., Nunes, H. R. C., & Goldberg, T. B. L. (2022). Effect of two combinations of low-dose oral contraceptives on adolescent bone mass: A clinical trial with 2 years follow-up. Medicine, 101(37), e30680. https://doi.org/10.1097/MD.0000000000030680

Farr Zuend, C., Noël-Romas, L., Hoger, S., McCorriser, S., Westmacott, G., Marrazzo, J., Hillier, S. L., Dezzutti, C., Squires, K., Bunge, K. E., & Burgener, A. (2021). Influence of dapivirine vaginal ring use on cervicovaginal immunity and functional microbiome in adolescent girls. AIDS (London, England), 35(3), 369–380. https://doi.org/10.1097/QAD.0000000000002751

Hardy, L., Jespers, V., De Baetselier, I., Buyze, J., Mwambarangwe, L., Musengamana, V., van de Wijgert, J., & Crucitti, T. (2017). Association of vaginal dysbiosis and biofilm with contraceptive vaginal ring biomass in African women. PloS one, 12(6), e0178324. https://doi.org/10.1371/journal.pone.0178324

Hognert, H., Skjeldestad, F. E., Gemzell-Danielsson, K., Heikinheimo, O., Milsom, I., Lidegaard, Ø., & Lindh, I. (2018). Ecological study on the use of hormonal contraception, abortions and births among teenagers in the Nordic countries. BMJ open, 8(10), e022473. https://doi.org/10.1136/bmjopen-2018-022473

Konstantinus, I. N., Balle, C., Jaumdally, S. Z., Galmieldien, H., Pidwell, T., Masson, L., Tanko, R. F., Happel, A. U., Sinkala, M., Myer, L., Bosinger, S. E., Gill, K., Bekker, L. G., Jaspan, H. B., & Passmore, J. S. (2020). Impact of Hormonal Contraceptives on Cervical T-helper 17 Phenotype and Function in Adolescents: Results from a Randomized, Crossover Study Comparing Long-acting Injectable Norethisterone Oenanthate (NET-EN), Combined Oral Contraceptive Pills, and Combined Contraceptive Vaginal Rings. Clinical infectious diseases: an official publication of the Infectious Diseases Society of America, 71(7), e76–e87. https://doi.org/10.1093/cid/ciz1063

Kristjánsdóttir, J., Sundelin, C., & Naessen, T. (2018). Health-related quality of life in young women starting hormonal contraception: a pilot study. The European journal of contraception & reproductive health care: the official journal of the European Society of Contraception, 23(3), 171–178. https://doi.org/10.1080/13625187.2018.1455179

Lattakova, M., Borovsky, M., Payer, J., & Killinger, Z. (2009). Oral contraception usage in relation to bone mineral density and bone turnover in adolescent girls. The European journal of contraception & reproductive health care: the official journal of the European Society of Contraception, 14(3), 207–214. https://doi.org/10.1080/13625180902838828

Moreira, K. de A., Jesus, J. H. de, Geron, V. L. M. G., & Nunes, J. da S. (2022). Anticoncepcionais hormonais: benefícios e riscos de sua utilização pela população feminina. Revista Científica Da Faculdade De Educação E Meio Ambiente, 13(2), 45–80. https://doi.org/10.31072/rcf.v13i2.1139

Rizzo, A. D. C. B., Goldberg, T. B. L., Biason, T. P., Kurokawa, C. S., Silva, C. C. D., Corrente, J. E., & Nunes, H. R. C. (2019). One-year adolescent bone mineral density and bone formation marker changes through the use or lack of use of combined hormonal contraceptives. Jornal de pediatria, 95(5), 567–574. https://doi.org/10.1016/j.jped.2018.05.011

Santos, A. (2017). “Adeus, hormônios”: novas concepções sobre corpo, saúde e contracepção na perspectiva de mulheres jovens. [Disertação de mestrado - Universidade de São Paulo.]. São Paulo. http://www.en.wwc2017.eventos.dype.com.br/resources/anais/1499472198_arquivo_trabalh o_completo_fazendo_genero_final.pdf.

Schoenwolf, G. C.; Bleyl, S. B.; Brauer, P. R.; Franciswest, P. H. (2016). Larsen Embriologia Humana. (5a ed.), Elsevier

.

Schofield, C., Fischer, S. K., Townsend, M. J., Mosesova, S., Peng, K., Setiadi, A. F., Song, A., & Baruch, A. (2016). Characterization of IL-17AA and IL-17FF in rheumatoid arthritis and multiple sclerosis. Bioanalysis, 8(22), 2317–2327. https://doi.org/10.4155/bio-2016-0207

Skovlund, C. W., Mørch, L. S., Kessing, L. V., Lange, T., & Lidegaard, Ø. (2018). Association of Hormonal Contraception With Suicide Attempts and Suicides. The American journal of psychiatry, 175(4), 336–342. https://doi.org/10.1176/appi.ajp.2017.17060616

Souza, M. T. D., Silva, M. D. D., & Carvalho, R. D. (2010). Revisão integrativa: o que é e como fazer. Einstein, 8, 102-106. https://doi.org/10.1590/S1679-45082010RW1134

Veres, S., Miller, L., & Burington, B. (2004). A comparison between the vaginal ring and oral contraceptives. Obstetrics and gynecology, 104(3), 555–563. https://doi.org/10.1097/01.AOG.0000136082.59644.13

Zettermark, S., Perez Vicente, R., & Merlo, J. (2018). Hormonal contraception increases the risk of psychotropic drug use in adolescent girls but not in adults: A pharmacoepidemiological study on 800 000 Swedish women. PloS one, 13(3), e0194773. https://doi.org/10.1371/journal.pone.0194773

Published

10/10/2023

How to Cite

FONTENELE, A. J. de O. .; LIMA, A. A.; SILVA, C. S. da .; TARQUINO, R. P. .; GOMES, R. T. A. .; SILVA , M. E. D. .; GOMES, B. da S. . The use of hormonal contraceptives by adolescents and possible health risks: An integrative review . Research, Society and Development, [S. l.], v. 12, n. 10, p. e75121043385, 2023. DOI: 10.33448/rsd-v12i10.43385. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/43385. Acesso em: 23 dec. 2024.

Issue

Section

Health Sciences