The scenario of research on pharmaceutical care in the monitoring of childhood leukemia: An integrative review
DOI:
https://doi.org/10.33448/rsd-v12i11.43672Keywords:
Precursor T-cell lymphoblastic leukemia-lymphoma; Pharmaceutical services; Pharmacists.Abstract
Objective: To analyze the landscape of scientific research between 2012 and 2022 on pharmaceutical care in childhood leukemia, aiming to understand trends, advancements, and gaps. Methods: An integrative literature review was conducted using specific descriptors in the following databases: Medical Literature and Retrieval System Online (MEDLINE/PubMed) via the National Library of Medicine; Latin American and Caribbean Literature in Health Sciences (LILACS) accessed through the Virtual Health Library (BVS); and the Scientific Electronic Library Online (SciELO) portal. Results: Eight articles related to the topic were selected, with 62.5% of the articles being literature reviews, 25% (2/8) data surveys, and 12.5% (1/8) clinical trials. Of these, only three literature reviews emphasized the importance of the pharmacist's role in the treatment of childhood leukemia, while the other studies included the pharmacist in the multidisciplinary team without clearly highlighting their role. Conclusion: The pharmacist plays a crucial role in the care of children with ALL, participating in laboratory diagnostics, pharmacotherapeutic monitoring, early detection of complications, identification of toxicity, emotional support, and interprofessional interactions. However, there is a lack of recent studies on the subject, field research focusing on the pharmaceutical approach to the care of children with ALL, and works that integrate pharmacological therapy with complementary approaches and specialized nutrition. This identified gap suggests a promising area for future research.
References
Alves, M. F., da Silva Gomes, A., da Silva, C. J., & de Oliveira Silva, E. (2023). Assistência farmacêutica na automedicação pediátrica. Revista Multidisciplinar do Nordeste Mineiro, 3(1).
Bhatia, S., Landier, W., Hageman, L., Chen, Y., Kim, H., Sun, C. L., & Relling, M. V. (2016). Systemic exposure to thiopurines and risk of relapse in children with acute lymphoblastic leukemia: a children's oncology group study. JAMA Oncology, 2(4), 382-388.
Bjornard, K. L., Gilchrist, L. S., Inaba, H., Diouf, B., Hockenberry, M. J., Kadan-Lottick, N. S., & Ness, K. K. (2018). Peripheral neuropathy in children and adolescents treated for cancer. The Lancet Child & Adolescent Health, 2(10), 744-754.
Cardoso, M., & Marquez, C. O. (2023). O papel da assistência farmacêutica na oncologia pediátrica. Research, Society and Development, 12(6), e24012642337-e24012642337.
Carvalho, Á. S. R., de Souza, A. M., dos Santos Silva, I. B., de Medeiros, J. J. O., & de Almeida, A. C. G. (2023). O papel das células CAR-T na imunoterapia da leucemia linfoblástica aguda de células B: revisão sistemática. Research, Society and Development, 12(6), e4412642035-e4412642035.
Dorantes-Acosta, E., Zapata-Tarrés, M., Miranda-Lora, A. L., Reyes-López, A., Hernández, O. M., Cortés-Gallo, G., & Espinosa, J. G. (2012). Apoyo de organizaciones no gubernamentales a pacientes pediátricos con leucemia linfoblástica aguda afiliados al Seguro Popular en México. Boletín médico del Hospital Infantil de México, 69(3), 212-217.
Eichsteller, M. (2019). There is more than one way–a study of mixed analytical methods in biographical narrative research. Contemporary Social Science.
Gil, A. C. (2019). Métodos e técnicas de pesquisa social. (6a ed.), Ediitora Atlas SA.
Gupta, S., Jain, P., Kumar, L., Sharma, A., & Gupta, A. (2019). Role of clinical pharmacist in supportive care of pediatric oncology patients. Indian Journal of Pediatrics, 86(1), 25-29.
INCA. (2022). INCA estima 704 mil casos de câncer por ano no Brasil até 2025. Governo Federal. https://www.gov.br/inca/pt-br/assuntos/noticias/2022/inca-estima-704-mil-casos-de-cancer-por-ano-no-brasil-ate-2025#:~:text=S%C3%A3o%20esperados%20704%20mil%20casos,cerca%20de%2070%25%20da%20incid%C3%AAncia.
Marques, I. V., & Cabral, I. D. A. C. (2023). A centralidade materna no acompanhamento de crianças com leucemia linfóide aguda. Revista Goitacá, 2(1), 1-20.
Martinez-Contreras, L., Fortún-Prieto, A., & Campo-Díaz, M. C. (2023). Aspectos novedosos sobre las complicaciones neurológicas y cardiovasculares tardías en adultos con antecedente de leucemia linfoblástica aguda infantil. Revista de Ciencias Médicas de Pinar del Río, 27, 5612.
Nicolazzo, J., Ngo, S. N., & Snyder, M. E. (2017). Medication therapy management: A patient-centered approach. McGraw Hill Professional.
Nunes, T. S., de Carvalho, G. P., de Castro Junior, C. G., & Canabarro, S. T. (2019). Orientações ao paciente pediátrico com leucemia linfóide aguda em acompanhamento ambulatorial: perfil de toxicidades e adesão ao tratamento. Research, Society and Development, 8(6), e686992.
Partanen, M., Phipps, S., Russell, K., Anghelescu, D. L., Wolf, J., Conklin, H. M., & Jacola, L. M. (2021). Longitudinal trajectories of neurocognitive functioning in childhood acute lymphoblastic leukemia. Journal of Pediatric Psychology, 46(2), 168-178.
Rother, E. T. (2007). Systematic literature review X narrative review. Acta paulista de enfermagem, 20, v-vi.
Santos, J., de Sá, L. F. P., de Oliveira Mata, J. P., da Silva Teixeira, A., de Moraes Souza, A. V. S., Amorim, G. R., & Gonçalves, W. V. E. (2022). Diagnóstico da leucemia linfoblástica aguda em crianças. Research, Society and Development, 11(9), e39411919078-e39411919078.
Schultz, K. R., Carroll, A., Heerema, N. A., Bowman, W. P., Aledo, A., Slayton, W. B., & Davies, S. M. (2020). Long-term follow-up of pediatric acute lymphoblastic leukemia: what we have learned from the St. Jude total therapy studies. Blood, 114(2), 233-242.
Silva, C. D. S., de Sousa, R. R., & de Oliveira Cardoso, R. (2018). Leucemia linfocítica aguda na infância e suas complicações. Revista de Iniciação Científica e Extensão, 1(2), 109-113.
Simões, M. V. V., Martins, J. S., Vieira, S. L., Fernandes, W. C., & Santana, C. A. (2020). Cuidados farmacêuticos na adesão da terapia medicamentosa oral em pacientes onco-pediátricos. Pubsaúde, 8, 1-8.
Souza, M. O., Garcia, M. A. T. (2018) O acompanhamento clínico do farmacêutico na oncologia infantil. Revista Científica Eletrônica de Ciências da FAIT. 20(2), 77-81.
Teixeira, L., et al. (2020). Leucemia Infantil. UniAtenas, 12(1), 1-17.
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Copyright (c) 2023 Jessica Moraes de Melo; Fernanda Patrícia Pereira de Castro; Kelen Silvia Falcão Moraes; Charliana Aragão Damasceno
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