Oral leukoplakia: A potentially malignant oral lesion

Authors

DOI:

https://doi.org/10.33448/rsd-v12i12.44054

Keywords:

Oral leukoplakia; Biopsy; Oral neoplasms; Mouth mucosa.

Abstract

Introduction: Leukoplakia is essentially a clinical term for white lesions with potential malignancy. Its diagnosis is made both by clinical aspects and by eliminating other similar lesions. Case report: Patient C.I.O., 49 years old, sought the clinic of the Faculty of Dentistry of the Federal University of Alagoas, complaining of painless lesions in the region of the lip mucosa, hard and soft palate, and reported using homemade cigarettes. A biopsy of the lesions was performed, confirming the diagnosis of oral leukoplakia. Methodology: A search was carried out in the Google Scholar, PubMed and Medline databases, using the terms “Oral leukoplakia”, “Biopsy”, “Oral neoplasms” and “Mouth Mucosa”. Objective: The objective of this work is to report the case of a patient with leukoplakia manifesting in oral cavity. Results and discussion: Clinically, they can be homogeneous or non-homogeneous lesions and, histologically, the distinction can be made by the presence of dysplasia and its different degrees. Most chronic injuries develop in response to trauma and may be asymptomatic. Treatment consists of eliminating the cause, monitoring it and using medication, if necessary. Final considerations: Therefore, it is important to search and correct interpretation of lesions to avoid risk of malignancy.

References

Aguirre-Urizar, J. M. et al. (2017). Leucoplasia oral como enfermedad premaligna: diagnóstico, prognóstico y tratamento. Medicina Oral S.L, 17(4), 28. https://portal.guiasalud.es/wp-content/uploads/2018/12/GPC_557_Leucoplasia_oral.pdf

Aumont, C. (2019). O tratamento da leucoplasia hoje em dia. Instituto Universitário Egas Moniz. Atlas. https://comum.rcaap.pt/bitstream/10400.26/30552/1/Aumont_Corentin.pdf

Bremmer, J. F., Braakhuis, B. J., Ruijter-Schippers, H. J., Brink, A., Duarte, H. M., & Kuik, D. J. et al. (2018). A noninvasive genetic screening test to detect oral preneoplastic lesions. Lab Invest, 20(5), 8. https://doi.org/10.1038/labinvest.3700342

Bsoul, S. A., Huber, M. A., & Terezhalmy, C. T. (2005). Squamous cell carcinoma of the oral tissues: a comprehensive review for oral healthcare providers. J Contemp Dent Pract, 6(4), 12-14. https://pubmed.ncbi.nlm.nih.gov/16299602/

Bueno, J. C. et al. (2022). Leucoplasia Bucal: Aspectos Clínicos, Microscópicos, Etiologia e Conduta. Universidade de São Judas Tadeu. Atlas.

Castelnaux, M. M. et al. (2020). Caracterización clínica y epidemiológica de pacientes con leucoplasia bucal. MEDISAN, 24(1), 4-15. https://medisan.sld.cu/index.php/san/article/view/2516

Capella, D. L. et al. (2017). Proliferative verrucous leukoplakia: diagnosis, management and current advances. Brazilian Journal of Otorhinolaryngology, 83(5), 585–593. https://doi.org/10.1016/j.bjorl.2016.12.005

Carrard, V. C. (2018). Leucoplasia bucal: considerações a respeito do tratamento e do prognóstico. Revista da Faculdade de Odontologia de Porto Alegre, 59(1), 34–41. https://doi.org/10.22456/2177-0018.44770

De Paula, A. M. B. (2001). Leucoplasias bucais. Abordagem das características clínicas e do potencial de transformação maligna. Revista do CROMG, Belo Horizonte - Minas Gerais, 45 (3), 6-7. https://doi.org/10.1590/S1676-24442009000300008

Epstein, J. B., Gorsky, M., Lonky, S., Silverman, S., Epstein, J. D., & Bride, M. (2006). The efficacy of oral lumenoscopy (ViziLite) in visualizing oral mucosal lesions. Spec Care DentiSt, 4. 26(4), 171–174. https://doi.org/10.1111/j.1754-4505.2006.tb01720.x

Grinspan, D. (1973). Enfermedades de la boca, Tomo II, Patología. Clínica y terapéutica de la mucosa bucal, Mundi.

Herreros-Pomares, A. et al. (2023). On the Oral Microbiome of Oral Potentially Malignant and Malignant Disorders: Dysbiosis, Loss of Diversity, and Pathogens Enrichment. Int J Mol Sci, 24(4), 6-7. https://doi.org/10.3390/ijms24043466

Hernández-Pérez, F. et al. (2019). Leucoplasia homogénea de cavidad bucal. ORAL, 20(63), 2-3. https://www.medigraphic.com/pdfs/oral/ora-2019/ora1963d.pdf

Llanes, T. L. M. et al. (2022). Parámetros histomorfométricos de la mucosa bucal en pacientes portadores de leucoplasia con displasia epitelial. Rev. Finlay, Cienfuegos, 12(2), 151-159. http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S2221-24342022000200151&lng=es&tlng=es

Lombardo, E. M. et al. (2018). Leucoplasia bucal: considerações a respeito do tratamento e do prognóstico. Revista Da Faculdade De Odontologia De Porto Alegre, 59(1), 34–41. https://doi.org/10.22456/2177-0018.44770

Luders, P. C., & Brandão, B. J. F. (2021). Diagnóstico Precoce em Leucoplasia Oral. BWS Journal, 4(1), 1–7. https://bwsjournal.emnuvens.com.br/bwsj/article/view/272

Maia, H. C. et al. (2016). Potentially malignant oral lesions: clinicopathological correlations. Einstein (São Paulo), 14(1), 2. https://doi.org/10.1590/S1679-45082016AO3578

Neville, B. (2009). Patologia oral e maxilofacial. Atlas.

Oliveira, G. C. et al. (2018). Prevalência e correlação clínico-patológica dos casos de leucoplasia bucal diagnosticados no Laboratório de Histologia da ULBRA Canoas/RS. Rev Stomatos, 24(46), 10-12. https://docs.bvsalud.org/biblioref/2018/07/906990/sto-v24-n46-a03.pdf

Ramos, R. T. (2017). Leucoplasia Oral: conceitos e repercussões clínicas. Rev brasileira de odontologia, 74(1), 4-5. http://dx.doi.org/10.18363/rbo.v74n1.p.51.

Toledo, C. Y. et al. (2018). Caracterización clínico e histopatológica de la leucoplasia bucal. AMC, 22(4), 432-451. http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1025-02552018000400432&lng=es&tlng=es

Tommasi, A. F. (2014). Diagnóstico em Patologia Bucal. Atlas.

Yero-Mier, I. M. et al. (2023). Caracterización de la leucoplasia bucal. Clínica Estomatológica Docente Provincial Justo Ortelio Pestana Lorenzo. Rev Ciências Médicas, 27(1), 7-8. http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1561-31942023000100006&lng=es&tlng=es

Published

23/11/2023

How to Cite

GOMES, J. R. H. .; GAMA, S. B. de F. .; SANTOS, L. C. O. .; MALTA, B. F. M. .; SILVA, A. M. C. da .; MARQUES, M. P. .; SANTOS, C. da S. . Oral leukoplakia: A potentially malignant oral lesion . Research, Society and Development, [S. l.], v. 12, n. 12, p. e149121244054, 2023. DOI: 10.33448/rsd-v12i12.44054. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/44054. Acesso em: 22 nov. 2024.

Issue

Section

Health Sciences