Extrapulmonary tuberculosis with renal and intestinal involvement: A challenge in early diagnosis

Authors

DOI:

https://doi.org/10.33448/rsd-v12i14.44516

Keywords:

Extrapulmonary tuberculosis; Renal tuberculosis; Intestinal tuberculosis; Acute kidney injury.

Abstract

Extrapulmonary tuberculosis is a manifestation of lung disease that affects organs and systems other than the lungs. Its incidence has increased, especially in patients with immunosuppression. Diagnosis and treatment of this form of the disease are clinical challenges due to the diversity of affected organs. Symptoms vary depending on the affected location and accurate diagnosis requires a multidisciplinary approach. Brazil has a high burden of tuberculosis and the extrapulmonary form accounts for around 20% of reported cases. This study aims to present a recent case report of extrapulmonary tuberculosis with renal and intestinal involvement, analyzing the signs and symptoms manifested by the patient, the diagnostic approaches used and the treatment instituted based on the most up-to-date scientific evidence. A clinical case report methodology with descriptive qualitative characteristics was used, carried out at the Hospital located in the city of Taubaté/SP. The patient received appropriate treatment and had a satisfactory clinical and laboratory evolution, resulting in functional recovery. Currently, the patient continues to be monitored at the Municipal University Hospital of Taubaté, under the care of the Nephrology and Hepatology team.

References

Behr, M. A., Edelstein, P. H., & Ramakrishnan, L. (2019). Is Mycobacterium tuberculosis infection life long? BMJ (Clinical research ed.), 367, l5770. https://doi.org/10.1136/bmj.l5770)

Boletim epidemiológico, secretaria de vigilância em saúde e ambiente. Ministério da Saúde. (2023). https://www.gov.br/saude/pt-br/centrais-de-conteudo/publicacoes/boletins/epidemiologicos/especiais/2023/boletim-epidemiologico-de-tuberculose-numero-especial-mar.2023.

Cavalcante, E. F. O., & Silva, D. M. G. V. (2013). Perfil de pessoas acometidas por Tuberculose. Rev Rene. 14(4):720-9.

Chen, K., Malik, A. A., Nantasenamat, C., Ahmed, S., Chaudhary, O., Sun, C., Sheng, Y. J., Chen, W., Gang, W., Deng, C. L., & Ojha, S. C. (2020). Clinical validation of urine-based Xpert® MTB/RIF assay for the diagnosis of urogenital tuberculosis: A systematic review and meta-analysis. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 95, 15–21. https://doi.org/10.1016/j.ijid.2020.03.023

SBPT. (2021). Consenso sobre o diagnóstico da tuberculose da Sociedade Brasileira de Pneumologia e Tisiologia. J. bras. Pneumol, 47 (02). https://doi.org/10.36416/1806-3756/e20210054

SBPT. (2009). III Diretrizes para Tuberculose da Sociedade Brasileira de Pneumologia e Tisiologia. J Bras Pneumol. 35(10), 1018-1048.

Global Tuberculosis Report. (2023). https://iris.who.int/bitstream/handle/10665/373828/9789240083851-eng.pdf?sequence=1

Amaral, E. C. S. O., Nobre, M. do N., de Souza, A. P., Henriques Junior, J. A. B., Corrêa, S. A., & Dantas, B. P. (2023). Tuberculose extrapulmonar como causa de pericardite constritiva: um diagnóstico difícil que deve ser considerado. Brazilian Journal of Health Review, 6(3), 9386–9401. https://doi.org/10.34119/bjhrv6n3-079

Houben, R. M. G. J., Dodd, P. J. (2016). The Global Burden of Latent Tuberculosis Infection: A Re-estimation Using Mathematical Modelling. PLOS Medicine 13(10): e1002152. https://doi.org/10.1371/journal.pmed.1002152

Julien, S., et al. (2016). Six-month therapy for abdominal tuberculosis. Cochrane Database Of Systematic Reviews, p.1-46.

Junior Macedo, A. M., et al. (2022). Perfil epidemiológico da tuberculose no Brasil, com base nos dados proveninentes do DataSUS nos anos de 2021. Research, Society and Development, 11 (6), e22311628999

Macêdo Júnior, A. M.., Pontes Neta, M. L., Duarte, A. R. A., Soares, T. F. R., Medeiros, L. N. B., Alcoforado, D. S. G., Fonseca, M. C., Macedo, B. M., Nicoletti, G. P., & Marcos, G. C. (2022). Perfil epidemiológico da tuberculose no Brasil, com base nos dados provenientes do DataSUS nos anos de 2021. Research, Society and Development, 11(6), e22311628999. https://doi.org/10.33448/rsd-v11i6.28999

Krishnamoorthy, S., Palaniyandi, V., Kumaresan, N., Govindaraju, S., Rajasekaran, J., Murugappan, I., Ramanan, V., & Krishnan, M. N. (2017). Aspects of Evolving Genito Urinary Tuberculosis-A Profile of Genito Urinary Tuberculosis (GUTB) in 110 Patients. Journal of clinical and diagnostic research: JCDR, 11(9), PC01–PC05. https://doi.org/10.7860/JCDR/2017/25882.10557

Silva, D. R., Rabahi, M. F., Sant’Anna, C. C., Silva-Junior, J. L. R., Capone, D., Bombarda, S., Miranda, S. S., Rocha, J. L., Dalcolmo, M. M. P., Rick, M. F., Santos, A. P., Dalcin, P. de T. R., Galvão, T. S., & Mello, F. C. de Q.. (2021). Diagnosis of tuberculosis: a consensus statement from the Brazilian Thoracic Association. Jornal Brasileiro De Pneumologia, 47(2), e20210054. https://doi.org/10.36416/1806-3756/e20210054

Lewinsohn, D. M., Leonard, M. K., LoBue, P. A., Cohn, D. L., Daley, C. L., Desmond, E., Keane, J., Lewinsohn, D. A., Loeffler, A. M., Mazurek, G. H., O'Brien, R. J., Pai, M., Richeldi, L., Salfinger, M., Shinnick, T. M., Sterling, T. R., Warshauer, D. M., & Woods, G. L. (2017). Official American Thoracic Society/Infectious Diseases Society of America/Centers for Disease Control and Prevention Clinical Practice Guidelines: Diagnosis of Tuberculosis in Adults and Children. Clinical infectious diseases: an official publication of the Infectious Diseases Society of America, 64(2), 111–115. https://doi.org/10.1093/cid/ciw778

Lopes, A.J, et al. (2006). Tuberculose extrapulmonar: aspectos clínicos e de imagem. Pulmão RJ, 15(4), 253-261.

Capone, D, et al. (2006). Tuberculose. Revista do Hospital Universitário Pedro Ernesto, UERJ, 54-66.

Ramachandran, A., Das, C. J., & Razik, A. (2021). Male genital tract tuberculosis: a comprehensive review of imaging findings and differential diagnosis. Abdominal Radiology, 46, 1677-1686.

Rossoni, R. L. S. (2017). Tuberculose peritoneal: relato de caso e revisão bibliográfica.https://residenciamedica.ufes.br/sites/residenciamedica.ufes.br/files/field/anexo/roberta_leal_silva_rossoni_02.pdf; p.32-p35.

RotilliK. W., & ValenzuelaR. G. V. (2022). A correlação entre a tuberculose e o desenvolvimento de lesão renal: uma revisão integrativa. Revista Eletrônica Acervo Saúde, 15(3), e10051. https://doi.org/10.25248/reas.e10051.2022

Sotgiu, G. & Migliori, G.B. (2019). Pulmonary Tuberculosis. In: Palange P, Rohde G, editors. ERS Handbook of Respiratory Medicine. 3rd ed. Lausanne: ERS.

Silva, D. R., Rabahi, M. F., Sant’Anna, C. C., Silva-Junior, J. L. R., Capone, D., Bombarda, S., Miranda, S. S., Rocha, J. L., Dalcolmo, M. M. P., Rick, M. F., Santos, A. P., Dalcin, P. T. R., Galvão, T. S., & Mello, F. C. Q. (2021). Diagnosis of tuberculosis: a consensus statement from the Brazilian Thoracic Association. Jornal Brasileiro De Pneumologia, 47(2), e20210054. https://doi.org/10.36416/1806-3756/e20210054

World Health Organization. (2021). Global tuberculosis report 2019. https://apps.who.int/iris/bitstream/handle/10665/329368/9789241565714-eng.pdf?ua=1

World Health Organization. (2022). Global Tuberculosis Report 2022. https://www.who.int/teams/global-tuberculosis-programme/tb-reports/global-tuberculosis-report-2022

Published

21/12/2023

How to Cite

ARAÚJO, F. G. A. de .; SAOTOME, L. .; PIERINI, J. L. de G. .; RUIVO, G. F. . Extrapulmonary tuberculosis with renal and intestinal involvement: A challenge in early diagnosis. Research, Society and Development, [S. l.], v. 12, n. 14, p. e80121444516, 2023. DOI: 10.33448/rsd-v12i14.44516. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/44516. Acesso em: 25 dec. 2024.

Issue

Section

Health Sciences