Dental conduct in petients using oral anticoagulants: Integrative literature review

Authors

DOI:

https://doi.org/10.33448/rsd-v13i3.45133

Keywords:

Anticoagulants; Hemorrhagic; Planning; Dentistry.

Abstract

Anticoagulant medications play a fundamental role in the treatment of several conditions associated with thrombotic risk, such as coronary artery disease and venous thrombosis, although their main adverse effect is the risk of hemorrhage. In this study, we focused on the evaluation of several anticoagulant medications, including acetylsalicylic acid (Aspirin®, Tromalyt®), clopidogrel (Plavix®, Iscover®), vitamin K antagonists such as Warfarin (Warfarine®, Marevan®), and NOACs such as Dabigatran (Pradaxa®), Rivaroxaban (Xarelto®), Edoxaban (Lixiana®) and Apixaban (Eliquis®). The importance of individualized planning in the dental treatment of these patients was highlighted. The objective of this study was to present safe protocols available for the dental management of patients using oral anticoagulants. An integrative literature review was carried out, carefully selecting national and international articles to analyze the influence of these medications on oral surgical procedures. Disagreements were found between authors, with some suggesting that suspending medication is not feasible due to the risks, while others emphasize an individualized approach, suspending medication if necessary, together with the doctor. It was concluded that the number of patients using anticoagulants is on the rise and, therefore, it is crucial that dental surgeons are prepared to provide safe care, thus minimizing the risk of bleeding complications.

References

Abayon, M. et al. (2016). Dental management of patients on direct oral anticoagulants: case series and literature review. Quintessence International, 47, 687-96.

Abdullah, W, Khalil, H (2014). Dental extraction in patients on warfarin treatment. Clinical, Cosmetic and Investigational Dentistry, 6, 65-69.

Afonso, A. et al., (2016). A terapêutica antitrombótica: atual e em desenvolvimento. Angiologia e Cirurgia Vascular, 12, 171.

Breik, O. et al., (2014). Protocol in managing oral surgical patients taking dabigatran. Australian Dental Journal. 59(3), 296-301.

Broekema, F. I. et al., (2014). Risk of bleeding after dentoalveolar surgery in patients taking anticoagulants. Britsh Journal of Oral and Maxilofacial Surgery. 52(3).

Carrasco, L.B.C (2020). Control de la hemostasia primaria y secundaria post exodoncia en pacientes con discrasias sanguíneas. 49f. Trabalho de conclusão de curso (Graduação em Odontologia) - Universidad de Guayaquil, Equador

Curto, A. & Curto, D.& Sanchez, L (2016). Managing patients taking edoxaban in dentistry. Journal section: Odontostomatology for the disabled or special patinetes, 9(2), 308-11.

Dantas, A. K. & Deboni, M. C. Z. & Piratininga, J. L. (2009). Cirurgias odontológicas em usuários de anticoagulantes orais. Revista Brasileira de Hematologia e Hemoterapia, 31(5).

Colmanetti, L. & Taline Y. I (2018). Cuidados pré e pós-operatório em pacientes que usam anticoagulantes: revisão de literatura. Trabalho de conclusão de curso (Graduação em Odontologia) - Universidade de Uberaba, Uberaba.

Dinkova, A., Kirova, D. & Delev, D (2013). Management of patients on anticoagulant therapy undergoing dental surgical procedures. review article. Journal of IMAB-Annnal proceeding (Scientific Papers), 19(4).

Garg, V. & Halperin, J (2013). Novel antiplatelet and anticoagulant agents in the cardiac care unit.Cardiol Clin, 31(4), 533-44.

Gerzson, A. et al., (2016). Dental surgery in patients undergoing therapy with antiplatelet drugs and oral anticoagulants: a literature review. J Clin Dent Res, 13(2), 100.

Gröbe, A. et al. (2015). Postoperative bleeding risk for oral surgery under continued clopidogrel antiplatelet therapy. Hindawi Publishing Corporation BioMed Research International, 4.

Lillis, T. et al. (2011). Safety of dental extracions during uninterrupted single or dual antiplatelet treatment. Am J Cardiol. 108(7), 964-967.

López-galindo, M.& Bagán, J. (2015). Apixaban and oral implications. J Clin Exp Dent, 7(4), 528-34.

Malik, A. & Majeed, S. (2020). Effect of antiplatelet therapy on minor dental procedures. National Journal of Maxillofacial Surgery. 11(1), 64-6.

Medeiros, F (2014). Extração dentária em pacientes com doença arterial coronariana em terapia antiplaquetária dual. 2014. 103f. Tese (Doutorado em Odontologia) – Universidade de São Paulo, São Paulo

Miller, S. G. & Miller, C. S (2018). Direct oral anticoagulants: a retrospective study of bleeding, behavior, and documentation. Oral Diseases. 24(1-2), 243-248.

Mingarro-de-león, A. Chaveli-lópez, B. & Galvadá-esteve, C. (2014). Dental Manegement of patientes receiving anticoagulant and/or antiplatelet tratment. J Clin Exp Dent, 6(2), 155-61.

Muñoz-corcuera, M. et al. (2016). Dabigatran: a new oral anticoagulant. Guidelines to follow in oral surgery procedures. a systematic review of the literature. Med Oral Patol Oral Cir Bucal, 21(6), e679-e688.

Pereira, C. M. et al. (2011). Thooth extraction in patients on oral anticoagulants: prospective study conducted in 108 brazilian patients. ISRN Dentistry. 203619.

Pessoti, C (2013). Estudo comparativo do uso de antiagregante plaquetário e anticoagulante oral na profilaxia da trombose em pacientes submetidos à operação cavopulmonar total com tubo extracardíaco: análise ecocardiográfica, angiotomográfica, cintilográfica, laboratorial e clínica. 106f. Tese (Doutorado em Ciências) - Universidade de São Paulo, São Paulo.

Silva, M (2019). Conduta na prática odontológica diante do paciente em uso de medicação anticoagulante e antiagregante plaquetária: revisão bibliográfica. 20f. Trabalho de conclusão de curso (Graduação em Odontologia) – Centro Universitário Tiradentes, Recife,

Souza, N (2019). Ocorrências de sangramento em procedimentos cirúrgicos odontológicos nos pacientes em terapia com os novos anticoagulantes orais: uma revisão de literatura. 31f. Trabalho de conclusão de curso (Graduação em Odontologia) – Centro Universitário UNIFACVEST, Lages.

Published

08/03/2024

How to Cite

GARCIA, M. E.; AMARAL, G. O. .; RAUCCI, K.; MOURA, K. dos S. .; FACO, E. F. de S. .; PEREIRA, F. P. Dental conduct in petients using oral anticoagulants: Integrative literature review . Research, Society and Development, [S. l.], v. 13, n. 3, p. e1713345133, 2024. DOI: 10.33448/rsd-v13i3.45133. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/45133. Acesso em: 8 may. 2024.

Issue

Section

Health Sciences