Endometriosis and infertility: Updates on the pathophysiological aspects and treatment of the association
DOI:
https://doi.org/10.33448/rsd-v13i8.46696Keywords:
Endometriosis; Infertility; Treatment.Abstract
Introduction: Endometriosis is a benign gynecological disorder that mainly affects women of childbearing age. As a multisystem disease, in addition to the female reproductive system, intestinal portions and structures of the urinary system can also be affected. Its pathophysiology is complex and multifactorial, as is establishing the diagnosis. Treatment is multidisciplinary and multimodal. Objective: The aim of this study was to evaluate the clinical, epidemiological and pathophysiological aspects of the association between infertility and endometriosis. Materials and Methods: This is an integrative literature review on the general clinical characteristics of the association between endometriosis and infertility. The PICO strategy was used to develop the guiding question. In addition, the descriptors "Endometriosis"; "Infertility"; "Treatment" were cross-referenced in the National Library of Medicine (PubMed MEDLINE), Scientific Electronic Library Online (SCIELO), Ebscohost, Google Scholar and Virtual Health Library (VHL) databases. Results and Discussion: The studies show that the association between endometriosis and infertility involves specific nuances within medicine, including pathophysiological, clinical, epidemiological and therapeutic aspects. Conclusion: The association between infertility and endometriosis is already well established in the literature and involves the interaction of multiple pathophysiological factors. In order to deal with it correctly, there are now drug and surgical techniques as well as assisted reproduction techniques, and the doctor must analyze and select the most appropriate treatment for each patient.
References
Coccia, M. E., Nardone, L., & Rizzello, F. (2022). Endometriosis and Infertility: A Long-Life Approach to Preserve Reproductive Integrity. International Journal of Environmental Research and Public Health, 19(10), 6162. https://doi.org/10.3390/ijerph19106162
Almeida, R. V. de, Guimarães, V. de P. R., Kurosawa, J. A. A., Mileo, A. B. V., & Yasojima, E. Y. (2022). Tratamento cirúrgico da Endometriose Pélvica - revisão de literatura / Surgical treatment of Pelvic Endometriosis - literature review. Brazilian Journal of Health Review, 5(3), 11920–11934. https://doi.org/10.34119/bjhrv5n3-323
Apolinário, P. A., Pinheiro, L. E. G., & Sousa, M. N. A. de. (2023). O papel da cirurgia na endometriose. Revista Eletrônica Acervo Saúde, 23(1), e11772. https://doi.org/10.25248/reas.e11772.2023
Bonavina, G., & Taylor, H. S. (2022). Endometriosis-associated infertility: From pathophysiology to tailored treatment. Frontiers in Endocrinology, 13. https://doi.org/10.3389/fendo.2022.1020827
Broi, M. G. D., Ferriani, R. A., & Navarro, P. A. (2019). Ethiopathogenic mechanisms of endometriosis-related infertility. JBRA Assisted Reproduction. https://doi.org/10.5935/1518-0557.20190029
Carneiro, H. L., Figueiredo, B. Q. de, Machado, K. S., Cunha, L. L. P. da, Pereira, R. M. P., Naves, P. G. R., Silva, J. L. A., Lage, L. T., Sousa, J. M. de, & Souza, R. L. de. (2023). O papel da endometriose na infertilidade feminina: uma revisão integrativa de literatura. Research, Society and Development, 12(3), e6612340529–e6612340529. https://doi.org/10.33448/rsd-v12i3.40529
Didziokaite, G., Biliute, G., Gudaite, J., & Kvedariene, V. (2023). Oxidative Stress as a Potential Underlying Cause of Minimal and Mild Endometriosis-Related Infertility. International Journal of Molecular Sciences, 24(4), 3809. https://doi.org/10.3390/ijms24043809
Federação Brasileira das Associações de Ginecologia e Obstetrícia (FEBRASGO). Endometriose. São Paulo: FEBRASGO, 2021 (Protocolo FEBRASGO-Ginecologia, n. 78/Comissão Nacional Especializada em Endometriose).
Filip, L., Duică, F., Prădatu, A., Crețoiu, D., Suciu, N., Crețoiu, S. M., Predescu, D.-V., Varlas, V. N., & Voinea, S.-C. (2020). Endometriosis Associated Infertility: A Critical Review and Analysis on Etiopathogenesis and Therapeutic Approaches. Medicina, 56(9), 460. https://doi.org/10.3390/medicina56090460
Flávia, M., Ferreira, S., Adriane Farias Patriota, Girliane, A., Inaia Mackert Pascoal, Luiz Gonçalves Filho, Vieira, I., Silva, & Silva. (2022). Endometriose e seus desafios no diagnóstico e tratamento: revisão integrativa da literatura. 15(9), e10979–e10979. https://doi.org/10.25248/reas.e10979.2022
Gama, A. V., Crystina, M., Júlia, M., Pereira, K., Maillany Amorim Gomes, Gabriela Moreira Lima, Costa, S., Catarina, A., & Carolinne Lisboa Silva. (2023). A endometriose e sua abordagem cirúrgica. Brazilian Journal of Development, 9(6), 19151–19161. https://doi.org/10.34117/bjdv9n6-030
Hodgson, R. M., Lee, H. L., Wang, R., Mol, B. W., & Johnson, N. (2020). Interventions for endometriosis-related infertility: a systematic review and network meta-analysis. Fertility and Sterility, 113(2), 374-382.e2. https://doi.org/10.1016/j.fertnstert.2019.09.031
Horne, A. W., & Missmer, S. A. (2022). Pathophysiology, diagnosis, and management of endometriosis. BMJ, 379(379), e070750. https://doi.org/10.1136/bmj-2022-070750
Pinto, L. V. R. C. P., Saleh, K. W., Barbosa, L. de A., Pinto, A. C. A., Sagrillo, I. F., Araujo, H. L. O. de, Lucindo, I. M. T., & Roza, T. C. B. N. (2022). Endometriose e infertilidade: relação e tratamento / Endometriosis and infertility: relationship and treatment. Brazilian Journal of Health Review, 5(2), 5889–5898. https://doi.org/10.34119/bjhrv5n2-165
Shan, J., Da Jin Li, & Wang, X. (2023). Towards a Better Understanding of Endometriosis-Related Infertility: A Review on How Endometriosis Affects Endometrial Receptivity. Biomolecules, 13(3), 430–430. https://doi.org/10.3390/biom13030430
Smolarz, B., Szyłło, K., & Romanowicz, H. (2021). Endometriosis: Epidemiology, Classification, Pathogenesis, Treatment and Genetics (Review of Literature). International Journal of Molecular Sciences, 22(19), 10554. https://doi.org/10.3390/ijms221910554
Souza, M. T. de, Silva, M. D. da, & Carvalho, R. de. (2010). Revisão integrativa: o que é e como fazer. Einstein (São Paulo), 8(1), 102–106. https://doi.org/10.1590/s1679-45082010rw1134.
Snyder, H. (2019). Literature review as a research methodology: An overview and guidelines. Journal of business research, 104, 333-339.
Vercellini, P., Viganò, P., Bandini, V., Buggio, L., Berlanda, N., & Somigliana, E. (2023). Association of endometriosis and adenomyosis with pregnancy and infertility. Fertility and Sterility, 119(5), 727–740. https://doi.org/10.1016/j.fertnstert.2023.03.018
Vieira, G. C. D., Silva, J. A. C. da, Padilha, R. T., & Padilha, D. de M. M. (2020). Endometriose: causas, implicações e tratamento da infertilidade feminina através das técnicas de reprodução assistida. Research, Society and Development, 9(10), e6859109128. https://doi.org/10.33448/rsd-v9i10.9128
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Luana Moreira Resende Nunes; Marcela Pereira Toledo; Luísa Moreira Resende Nunes; Yasmin Lage Altivo; Bruna Carvalho Veloso
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.