The impact of overweight on clinical complications caused by COVID-19: A systematic review
DOI:
https://doi.org/10.33448/rsd-v9i7.4791Keywords:
Overweight; Obesity; Coronavirus; Risk Factors; Sars-Cov-2.Abstract
The objective was to evaluate and show the main impacts of excessive corporal weight, related to the complexities and clinical outcomes, caused by SARS-CoV-2. This work is based in a systematic review of published works and driven by the question: “Which are the main questions about obesity as a risk factor related to the clinical complications of COVID and severe respiratory diseases?”, the researches were realized based on MEDLINE data, through the keywords available in DeCS/MeSH: Coronavírus/Coronavirus, Obesidade/ Obesity and SARS-Cov-2/Betacoronavirus, and then through pre-fixed criteria, were selected 13 articles to make part of the same research. The severity of the infection caused by SARS-CoV-2 increased with the CMI, in patients with overweight, the needs for intensive therapy and mechanical ventilation were about 50%. The overweight can act as a deregulator, harming the lymphoids and myeloides answers, which will disrupt the immunological system and extend the infections, contributing to a higher proliferation of viral infections, as occurs in the COVID-19 pandemics, besides, those individuals usually have some pre-existing metabolic and endocrine disturbances which can contribute to the use of the immune system, inflammatory and viral pathogens. The obesity and overweight are directly related with the intensification of patients symptoms with COVID-19, trough disturbances in the immune system, lack of respiratory capability and complacency of the respiratory system, and by the presence of associated diseases to that pathology.
References
Albuquerque, C. G., Andrade, F. M. D., Rocha, M. A. A., Oliveira, A. F. F., Ladosky, W., Victor, E. G., & Rizzo, J. A. (2015). Determinig Respiratory System Resistance And Reactance By Impulse Oscillometry In Obese Individuals. Rev J Bras Pneumol., 41 (5), 422-426. Retrieved from: https://www.scielo.br/pdf/jbpneu/v41n5/pt_1806-3713-jbpneu-41-05-00422.pdf. doi: 10.1590/S1806-37132015000004517
Aminian, A., Kermansaravi, M., Azizi, S., Alibeigi, P., Safamanesh, S., Mousavimaleki, A., Rezaei, M. T., Faridi, M., Mokhber, S., Pazouki, A., & Safari, S. (2020). Bariatric Surgical Practice During The Initial Phase Of Covid-19 Outbreak. Rev Obes Surg. 1 (1), 1-4. Retrieved from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168566/. doi: 10.1007/s11695-020-04617-x
Bevenuto, D., Giovannetti, M., Ciccozzi, A., Spoto, S., Angeletti, S., & Ciccozzi, M. (2020). The 2019-new coronavirus epidemic: Evidence for virus evolution. J Med Virol., 92 (1), 455-459. Retrieved from: https://arca.fiocruz.br/bitstream/icict/40020/2/MartaGiovanetti_ MassimoCiccozzi_etal_IOC_2020.pdf. doi:10.1002/jmv.25688
Brasil. Ministério da Saúde. Secretaria de Ciência. (2012). Tecnologia e Insumos Estratégicos. Diretrizes metodológicas: elaboração de revisão sistemática e metanálise de ensaios clínicos randomizados. [acesso em 12 fev. 2020]. Retrieved from: http://bvsms.saude.gov.br/bvs/publicacoes/diretrizes_metodologicas_elaboracao_sistematica.pdf
Brasil. Ministério da Saúde. (2018). Vigilância de Fatores de Risco e Proteção para Doenças Crônicas por Inquérito Telefônico (VIGITEL). [acesso em 14 fev 2020]. Retrieved from: https://portalarquivos2.saude.gov.br/images/pdf/2019/julho/25/vigitel-brasil-2018.pdf
Brasil. Ministério da Saúde (2020a). Protocolo de manejo clínico para o novo-coronavírus (2019-nCoV. [acesso em 12 fev 2020]. Retrieved from: https://portalarquivos2. saude.gov.br/images/pdf/2020/fevereiro/11/protocolo-manejo-coronavirus.pdf
Brasil. Ministério da Saúde. (2020b). Coronavírus (COVID-19). [acesso em 12 fev 2020]. Retrieved from: https://coronavirus.saude.gov.br/sobre-a-doenca#o-que-e-covid
Brasil. Ministério da Saúde. (2020c). Boletim Epidemiológico Especial COE-COVID19. [acesso em 14 fev 2020]. Retrieved from: https://portalarquivos.saude.gov.br /images/pdf/2020/April/27/2020-04-27-18-05h-BEE14-Boletim-do-COE.pdf
De Lorenzo, A., Soldati, L., Sarlo, F., Calvani, M., Di Lorenzo, N., & Di Renzo, L. (2016). New obesity classification criteria as a tool for bariatric surgery indication. Rev World J Gastroenterol, 22 (2), 681-703. Retrieved from: https://www.ncbi.nlm.nih.gov/pmc/articles/ PMC4716069 /pdf/WJG-22-681.pdf. doi: 10.3748/wjg.v22.i2.681
Dietz, W., & Santos-Burgoa, C. (2020). Obesity and its Implications for COVID-19 Mortality. Rev Obesity. 28 (6), 1005. Retrieved from: https://onlinelibrary.wiley.com /doi/epdf/10.1002/oby.22818. doi: 10.1002/oby.22818
Donato, H., & Donato, M. (2019). Etapas na Condução de um Revisão Sistemática. Rev Acta Med Port., 32(3): 227-35. Retrieved from: https://www.actamedicaportuguesa.com /revista/index.php/amp/article/view/11923/5635. doi: 10.20344/amp.11923
Heinrich, K. M., Gurevich, K. G., Arkhangelskaia, A. N., Karazhelyaskov, O. P., & Poston, W. S. C. (2020). Despite Low Obesity Rates, Body Mass Index Under-Estimated Obesity Among Russian Police Officers When Compared To Body Fat Percentage. Rev Int J Environ Res Public Health, 17 (6), 1-7. Retrieved from: https://www.mdpi.com/1660-4601/17/6/1937/htm. doi: 10.3390/ijerph17061937
Kim, B. K., & Shin, A. Y. (2020). Males with Obesity and Overweight. J Obes Syndr., 29 (1), 18-25. Retrieved from: http://www.jomes.org/journal/view.html?doi=10.7570/jomes20008. doi: 10.7570/jomes20008
Kucharski, A. J., Russel, T. W., Diamond, C., Liu, Y., Edmunds, J., Funk, S., & Eggo, R. M. (2020). Early dynamics of transmission and control of COVID-19: a mathematical modellung study. Rev Lancet Infect Dis., 20 (1), 553-58. Retrieved from: https://www.thelancet.com/action/showPdf?pii=S1473-3099%2820%2930144-4. doi: 10.1016/S1473-3099(20)30144-4
Kyle, T. K., Dhurandhar, E. J., & Allison, D. B. (2016). Regarding Obesity as a Disease: Evolving Policies and Their Implications. Rev Endocrinol Metab Clin North Am., 45 (3), 511-520. Retrieved from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988332/. doi: 10.1016/j.ecl.2016.04.004
Li, H., Liu, S. M., Yu, X. H., Tang, S. L., & Tang, C. K. (2020). Coronavirus disease 2019 (COVID-19): current status and future perspective. International Journal of Antimicrobial Agents., 20 (1), 54. Retrieved from: https://reader.elsevier.com/reader/sd/pii /S0924857920301011?token=80A397C312C4CBFCA2B6423C00872E35EC8C1A2B9FBDED3599BAF318A4E9C6B68062B64E400B42FB970CBAC3A696D78D. doi:10.1016 /j.ijantimicag. 2020.105951
Lima, C. M. A. (2020). Information about the new coronavirus disease (COVID-19). Rev Radiol Bras., 53 (2), 5-6. Retrieved from: https://www.scielo.br/pdf/rb/v53n2/pt_0100-3984-rb-53-02-000V.pdf. doi: 10.1590/0100-3984.2020.53.2e1
Medeiros, E. A. S. (2020). Desafios para o enfrentamento da pandemia COVID-19 em hospitais universitários. Rev Paul Pediatr., 38 (1), e2020086. Retrieved from: https://www.scielo.br/pdf/rpp/v38/pt_1984-0462-rpp-38-e2020086.pdf. doi: 10.1590/1984-0462/2020/38/2020086
Melnyk, B. M., & Fineout-Overholt, E. Making the case for evidence-based practice. In: Melnyk, BM, Fineout-Overholt, E. Evidence-based practice in nursing & healthcare: a guide to best practice. Philadelphia: Lippincott Williams & Wilkins; 2005. p. 3-24.
Moher, D., Liberati, A., Tetzlaff, J., & Altman, D. G. (2015). Principais itens para relatar Revisões Sistemáticas e Meta-análises: A recomendação PRISMA. Rev Epidemiol Serv Saúde, 24 (2), 335-342. Retrieved from: https://www.scielo.br/pdf/ress/v24n2/2237-9622-ress-24-02-00335.pdf. doi: 10.5123/S1679-49742015000200017
Moser, J. S., Galindo-Fraga, A., Ortiz-Hernández, A. A., Gu, W., Hunsberger, S., Galán-Herrera, J. F., Guerrero, M. L., Ruiz-Palacios, G. M., & Beigel, J. H. (2019). Underwight, Overweight And Obesity As Independent Risk Factors For Hospitalization In Adults And Children From Influenza And Other Respiratory Viruses. Rev Influenza Other Respir Viruses., 13 (1), 3-9. Retrieved from: https://onlinelibrary.wiley.com /doi/epdf/10.1111/irv.12618. doi: 10.1111/irv.12618
Mota, L. P., Barbosa, V. S., Carvalho, V. M., Nunes, E. C., Sousa, M. J. F., Madureira, G. N., Castro, V. L., Rodrigues, F. S., Rodrigues, G. R. S., Oliveira, Y. M. M. S., Neto, J. W. V. M., Soares, J. M., Barbosa, C. E. P., Pereira, A. O., Oliveira, C. R., & Alves, V. K. M. (2020). Características clínicas e laboratoriais da infecção pelo Covid-19. Rev. Research Society and Development., 9 (7), 1-8. Retrieved from: https://rsd.unifei.edu.br/index.php/rsd/article /view/3656/2916. doi: 10.33448/rsd-v9i7.3656
Paudel, S., Dangal, G., Chalise, A., Bhandari, T. R., & Dangal, O. (2020). The Coronavirus Pandemic: What Does the Evidence Show?. J Nepal Health Res Counc., 18 (1), 1-9. Retrieved from: https://www.researchgate.net/profile/Ganesh_Dangal/publication/340778296_The_Coronavirus_Pandemic_What_Does_the_Evidence_Show/links/5e9f2d8792851c2f52ba4055/The-Coronavirus-Pandemic-What-Does-the-Evidence-Show.pdf. doi: 10.33314/jnhrc.2596
Petrilli, C. M., Jones, S. A., Yang, J., Rajagopalan, H., O’Donnell, L. F., Chernyak, Y., Tobin, K. A., Cerfolio, R. J., Francois, F., & Horwitz, L. I. (2020). Factors association with hospitalization and critical illness among 4,103 patients with COVID-19 disease in New York City. Rev medRxiv., 68 (1), 2-25. Retrieved from: https://www.medrxiv.org/content/ 10.1101/2020.04.08.20057794v1.full.pdf. doi: 10.1101/2020.04.08.20057794
Piva, S., Filippini, M., Turla, F., Cattaneo, S., Margola, A., De Fulviis, S., Nardiello, I., Beretta, A., Ferrari, L., Trotta, R., Erbici, G., Focà, E., Castelli, F., Rasulo, F., Lanspa, M. J., & Rasulo, F. (2020). Clinical presentation and initial management critically ill patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV 2) infection in Brescia, Italy. Rev. J. Crit Care, 58 (1), 29-33. Retrieved from: https://reader.elsevier.com/reader /sd/pii/S0883944120305475?token=C89AB44BEFE3225506DD5D4EF5F10EAA65CBD931E1DF9FC34DAD082AAD8E61400238FE6BC40F0DC56641154D1ABAA0E5. doi: 10.1016/j.jcrc.2020.04.004
Puig-Domingo, M., Marazuela, M., & Giustina, A (2020). COVID-19 and endocrine diseases: A statement from the European Society of Endrocrinology. Rev Endocrine., 68 (1), 2-5. Retrieved from: https://link.springer.com/content/pdf/10.1007/s12020-020-02294-5.pdf. doi: 10.1007/s12020-020-02294-5
Rojas-Dotor, S., Segura-Méndez, N. H., Miyagui-Namikawa, K., & Mondragón-González, R. (2013). Expression of resistin, CXCR3, IP-10, CCR5 and MIP-1 α in obese patients with different severity of asthma. Rev Biol Res., 46 (1), 13-20. Retrieved from: https://scielo.conicyt.cl/pdf/bres/v46n1/art02.pdf. doi: 10.4067/S0716-97602013000100002
Ryan, P. M. D., & Caplice, N. M. (2020). Is Adipose Tissue A Reservoir For Viral Spread, Imunne Activation And Cytokine Amplification In Covid-19. Rev Obesity. 1 (1), 1-15. Retrieved from: https://onlinelibrary.wiley.com/doi/epdf/10.1002/oby.22843. doi: 10.1002/oby.22843
Simonnet, A., Chetboun, M., Poissy, J., Raverdy, V., Noulette, J., Duhamel, A., Labreuche, J., Mathieu, D., Pattou, F., & Jourdain, M. (2020). High Prevalence Of Obesity In Severe Acute Respiratory Syndrome Coronavirus-2 (Sars-Cov-2) Requiring Invasive Mechanical Ventilation. Rev Obesity. 1 (1), 1-15. Retrieved from: https://onlinelibrary.wiley.com /doi/epdf/10.1002/oby.22831. doi: 10.1002/oby.22831
Sousa, M. R. N., Barros, S. S., Silva, M., Oliveira, A. P. M., Rocha, G. M., & Oliveira, G. A. L. (2020). Patogênese e perspectivas de tratamento da COVID-19: uma revisão. Rev Research, Society and Development., 9 (7), 1-5. Retrieved from: https://rsd.unifei.edu.br/index.php/rsd/article/view/3730/3182. doi: 10.33448/rsd-v9i7.3730
World Health Organization. (2020). Q&A on Coronaviruses (COVID-19). [Acesso em 12 fev 2020]. Retrieved from: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/question-and-answers-hub/q-a-detail/q-a-coronaviruses#:~:text=symptoms
Zheng, K. I., Gao, F., Wang, X. B., Sun, Q. F., Pan, K. H., Wang, T. Y., Ma, H. L., Liu, W. Y., George, J., & Zheng, M. H. (2020). Obesity as a risk factor for greater severity of COVID-19 in patients with metabolic associated fatty liver disease. Rev Metabolism., 19 (1), e154244. Retrieved from: https://www.metabolismjournal.com/article/S0026-0495(20)30108-6/pdf. doi: 10.1016/j.metabol.2020.154244
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