Vascular mineralization associated with bone mineral disorder in a patient with chronic kidney disease - case report
DOI:
https://doi.org/10.33448/rsd-v9i8.6466Keywords:
Calcification; Dog; Kidney disease; Uremic syndrome.Abstract
Chronic kidney disease (CKD) is a common condition in the small animal practice and its presence is associated with polysystemic changes, such as bone mineral disorders related to the action of uremic toxins such as parathyroid hormone (PTH). The imbalance of homeostasis caused by excess PTH can lead to clinical repercussions such as fibrous osteodystrophy, tissue calcifications and progression of kidney disease. The aim of the present report is to describe the case of a four-year-old dog with CKD associated with bone mineral disorder with systemic repercussions such as fibrous osteodystrophy, arterial hypertension, concentric left ventricular hypertrophy and vascular calcifications.
References
Acierno, M. J., Brown, S., Coleman, A. E., et al. (2018). ACVIM Consensus statement: Guidelines for the identification, evaluation, and management of systemic hypertension in dogs and cats. Journal Veterinary Internal Medicine, 32(6), 1803-1822.
Alves, M. A. M. K., Crivellenti, L. Z., & Carvalho, M. B. (2014). Osteodistrofia fibrosa de origem renal em dois cães idosos: relato de caso. Revista Portuguesa de Ciências Veterinárias, 109(1), 51-56.
Babitt, J. L., & Lin, H. Y. (2012). Mechanisms of Anemia in CKD. Journal of American Society Nephrology, 23, 1631-1634.
Bagshaw, S. M., Hoste, E. A., Braam, B., Briguori, C., Kellum, J. A., Mc Ccullough, P. A., & Ronco, C. (2013). Cardiorenal Syndrome Type 3: pathophysiologic and epidemiologic considerations. Contribuitions to Nephrology, 182, 137-157.
Barberato, S. H., & Pecoits-Filho, R. (2010) Alterações ecocardiográficas em pacientes com insuficiência renal crônica em programa de hemodiálise, Arquivos Brasileiros de Cardiologia, 94(1), 140-146.
Berndt, T., & Kumar, R. (2007). Phosphatonins and the regulation of phosphate homeostasis. Veterinary Physiology, 69(1), 341-359.
Boon, J. A. (2011). Veterinary Echocardiography. Wiley-Blackwell; Edição: (2nd ed). 610p.
Brito, G. J. F., Nagode, L. A., Schenck, P. A., & Chew, D. J. (2013). Calcitriol, calcidiol, parathyroid hormone, and fibroblast growth factor-23 interactions in chronic kidney disease. Journal of Veterinary Emergency and Critical Care, 23(2), 134-162.
Brito, G. J. F., Schenck, P. A., & Chew, D. J. A. (2017). Quick Reference on Hypocalcemia. Veterinary Clinics of North America: Small Animal Practice, 47(2), 249-256.
Chew, D. J., Dibartola, S. P., & Schenck, P. A. (2012) Urologia e Nefrologia do Cão e do Gato. Rio de Janeiro: Elsevier, (2a ed.). 536p.
Chiu, Y. W., Adler, S. G., Budoff, M. J., Takasu, J., Ashal, J., & Mehrotra, R. (2010). Coronary artery calcification and mortality in diabetic patients with proteinuria. Kidney International, 77(6), 1107-1114.
Custódio, M. R., Canziani, M. E. F., Moyses, R. M. A., Barreto, F. C., Neves, C. L., Oliveira, R. B., Karohl, C., Sampaio, E. A., Gueiros, J. E. B., Jorgetti, V., & Carvalho, A. B. (2013). Protocolo clínico e diretrizes terapêuticas para o tratamento do hiperparatireoidismo secundário em pacientes com doença renal crônica. Jornal Brasileiro de Nefrologia, 35(4), 308-322.
D’avila, M. S., França, T. N., Peixoto, P. V., Peixoto, T. C., Santos, A. M., Costa, S. Z. R., Santos, R. S., Gonçalves, T., & Nogueira, V. A. (2016). Avaliações morfológica e imuno-histoquímica (Troponina C) de lesões cardíacas em cães com doença renal crônica. Revista Brasileira de Medicina Veterinária, 38(Supl.2):128-138.
De Fornel-Thibaud, P., Blanchard, G., Escoffier-Chateau, L., Segond, S., Guetta, F., & Begon, D. (2007). Unusual case of osteopenia associated with nutritional calcium and vitamin D deficiency in an adult dog. Journal of the American Animal Hospital Association, 43(1), 52-60.
Doige, E. C., & Wiesbrode, S. E. (1998). Doença dos Ossos e das Articulações. In: Carlton, W. W. & Mc Gravi, M. D. (Eds.) Patologia Veterinária Especial de Thomson. (2a ed.) Porto Alegre: Artmed, 462-464.
Goutal, C. M., Keir, I., Kenney, S., Rush, J. E., & Freeman, L. (2010). Evaluation of acute congestive heart failure in dogs and cats: 145 cases (2007-2008) Journal of Veterinary Emergency and Critical Care, 20(3), 330–337.
Grauer, G. F. (2006). Distúrbios do Trato Urinário. In: Nelson, R. W., & Couto, C. G. (Eds.). Medicina Interna de Pequenos Animais. 2ed. Rio de Janeiro: Guanabara Koogan, 595-596.
IRIS-International Renal Interest Society. (2017). IRIS Staging of CKD (modified 2017), 5p. Disponível em: <http://www.iris-kidney.com>. Acesso em 08 jan. 2019.
Lees, G. E. (1996). Congenital renal disease – renal dysfunction. Veterinary Clinics of North America: small animal practice, 26(6), 1379-1399.
Locatelli, F., Canaud, B., Eckardt, K. U., Stenvinkel, P., Wanner, C., & Zoccali, C. (2003). Oxidative stress in end-stage renal disease: an emerging threat to patient outcome. Nephrology Dialysis Transplantation, 18, 1271-1280.
Martinelli, E., Locatelli, C., Bassis, S., Crosara, S., Paltrinieri, S., Scarpa, P., et al. (2016). Preliminary investigation of cardiovascular-renal disorders in dogs with chronic mitral valve disease. Journal of Veterinary Internal Medicine, 30(5), 1612-1618.
Mc Grotty, Y. (2008). Diagnosis and management of chronic kidney disease in dogs and cats. In Practice, 30(9), 502-507.
Meak, D. (2003). Distúrbios do sistema urogenital. In: Bichard, S. J., & Sherding, R. G. (Eds.) Manual Saunders: Clínica de Pequenos Animais. São Paulo: Roca, 1001-1029.
Mejía, N., Roman-Garcia, P., Miar, A. B., Tavira, B., & Cannata-Andía, J. B. (2011). Chronic kidney disease-mineral and bone disorder: a complex scenario. Nefrologia, 31(1), 514-519.
Opie, L. H. (2004). Overload Hypertrophy and Its Molecular Biology. In Heart Physiology From Cell to Circulation. 4ed. Philadelphia: Lippincott Williams & Wilkins, 402-427.
Ossareh, S. (2011). Vascular calcification in chronic kidney disease: mechanisms and clinical implications. Iran Journal of Kidney Disease, 5(1), 285-299.
Parker, V. J., Gilor, C., & Chew, D. J. (2015). Feline Hyperparathyroidism: Pathophysiology, diagnosis, and treatment of primary and secondary disease. Journal of Feline Medicine and Surgery, 17(5), 427-439.
Peres, L. A. B., & Pércio, P. P. V. (2014). Distúrbio mineral ósseo e calcificação vascular em pacientes renais crônicos. Brazilian Journal of Nephrology, 36(2), 201-207.
Polzin, D. J. (2011) Chronic kidney disease in small animals. Veterinary Clinics of North America: Small Animal Practice, 41(1), 15-30.
Polzin, D. J., Ross, S. Osborne, C. A. (2009). Calcitriol. In: Bonagura, J. D., & Twedt, D. C. (Eds.) Current Veterinary Therapy XIV. St. Louis: WB Saunders, 892-895.
Rusenov, A. (2010). A clinical case of secondary hyperparathyroidism in a four-month-old Pug puppy. Revue de Médecine Veterinaire, 161(12), 570-573.
Schiffrin, E. L., Lipman, M. L., & Mann, J. F. E. (2007). Chronic kidney disease: Effects on the cardiovascular system. Circulation, 116(16), 85-97.
Segev, G., Meltzer, H., & Shipov, A. (2016). Does secondary renal osteopathy exist in companion animals? Veterinary Clinics of North America: Small Animal Practice, 46, 1151-1162.
Serakides, R. (2011). Ossos e articulações. In: Santos, R. L., & Alessi, A. C. Patologia Veterinária. São Paulo: Roca, 647-696.
Stillion, J. R., & Ritt, M. G. (2009). Renal secondary hyperparathyroidism in dogs. Compendium (Yardley, PA), 31(6), E8-11.
Temmar, M., Liabeuf, S., Renard, C., Czernichow, S., Esper, N. E., Shahapuni, I., Presne, C., Makdassi, R., Andrejak, M., Tribouilloy, C., Galan, P., Safar, M. E., Choukroun, G., & Massy, Z. (2010). Pulse wave velocity and vascular cal¬cification at different stages of chronic kidney disease. Journal of Hypertension, 28(1), 163-169.
Tilley, L. P., & Smith Jr., F. W. K. (2008). Consulta Veterinária em 5 Minutos – Espécies Canina e Felina. (3a ed.). Barueri: Manole, 1604.
Vleet, J. F. V., & Ferrans, V. J. (2009). Sistema cardiovascular. In: Mc Gavin, M. D. & Zachary, J. F. (Eds), Bases da Patologia em Veterinária. Tradução da (4a ed.). Elsevier, Rio de Janeiro, 559-612.
Waki, M. F., Martorelli, C. R., Mosko, P. E., & Kogika, M. M. (2010). Classificação em estágios da doença renal crônica em cães e gatos - abordagem clínica, laboratorial e terapêutica. Ciência Rural [online], 40(10), 2226-2234.
Zatz, R. (2011). Doença/Insuficiência renal crônica. In: Zatz, R.; Seguro, A. C., & Malnic, G. Bases fisiológicas da nefrologia. Atheneu, São Paulo, 245-267.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2020 Rosemar de Almeida Freitas, Rosemar de Almeida Freitas, Bruno Ricardo Soares Alberigi, Bruno Ricardo Soares Alberigi, Bruno Ricardo Soares Alberigi, Mário dos Santos Filho, Bruno Ricardo Soares Alberigi, Gabriela de Carvalho Cid, Denise do Vale Soares, Rosemar de Almeida Freitas, Lumara Raeli Ligeiro, Rosaura Leite Sobrinho, Vivian de Assunção Nogueira Carvalho, Rosemar de Almeida Freitas, Gabriela de Carvalho Cid, Gabriela de Carvalho Cid, Lumara Raeli Ligeiro, Rosaura Leite Sobrinho, Gabriela de Carvalho Cid, Rosaura Leite Sobrinho, Denise do Vale Soares, Rosaura Leite Sobrinho, Denise do Vale Soares, Denise do Vale Soares, Vivian de Assunção Nogueira Carvalho, Vivian de Assunção Nogueira Carvalho, Lumara Raeli Ligeiro, Vivian de Assunção Nogueira Carvalho, Lumara Raeli Ligeiro
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
