Orofacial findings of congenital generalized lipodystrophy: a systematic review

Authors

DOI:

https://doi.org/10.33448/rsd-v9i8.6659

Keywords:

Congenital generalized lipodystrophy; Orofacial changes; Orofacial manifestations.

Abstract

This study aims to verify the orofacial findings of congenital generalized lipodystrophy (LGC) in patients diagnosed with this condition. This is a systematic review of the literature, carried out in accordance with the PubMed, Web of Science and Scopus databases. 14 studies published in the last 15 years that addressed the orofacial clinical findings of LGC were included. LGC is a rare autosomal recessive condition, presenting a wide variety of manifestations that affect the oral and facial regions. The main orofacial findings identified were prognathism, absence of facial subcutaneous fat, prominent frontal and supraorbital protrusions, low frontal hairline, triangular face, facial hirsutism, macroglossia, labial hypertrophy, abnormal dental morphology, dental caries, tooth absences, diastemas and crowding dental. The results indicate that LGC can cause significant orofacial changes in individuals, and it is important that these patients are monitored by a multidisciplinary health team, and that these professionals have knowledge based on scientific evidence regarding these clinical findings, to offer a better prognosis for these patients.

Author Biographies

Lucas Cavalcante de Sousa, Universidade Federal do Rio Grande do Norte

Graduando em Odontologia pela Universidade Federal do Rio Grande do Norte.

Amanda de Medeiros Amancio, Universidade Federal do Rio Grande do Norte

Graduanda em Odontologia pela Universidade Federal do Rio Grande do Norte.

Érika Giovana Carvalho da Silva, Universidade Federal do Rio Grande do Norte

 Fisioterapeuta (2018). Mestranda em Ciências da Reabilitação (FACISA-UFRN).

Francisca Jennifer Duarte de Oliveira, Universidade Federal do Rio Grande do Norte

Graduanda em Odontologia pela Universidade Federal do Rio Grande do Norte.

Gabriel Coutinho Gonçalves, Universidade Estadual do Ceará

Fisioterapeuta. Especialista em Residência Multiprofissional em Saúde da Família. Especialista em Micropolítica em Gestão e Trabalho em Saúde. Mestrando em Planejamento e Políticas Públicas (UECE). Centro de Estudos Sociais Aplicados - Programa de Políticas Públicas.

Dennys Ramon de Melo Fernandes Almeida, Universidade Federal do Rio Grande do Norte

Cirurgião-Dentista, especialista em Micropolíticas de Gestão e Trabalho em Saúde pela Universidade Federal Fluminense (UFF). É mestre em Patologia pela Universidade Federal do Ceará (UFC) e doutorado em Ciências Odontológicas pela Universidade Federal do Rio Grande do Norte (UFRN). Tem experiência na área de Odontologia, atuando principalmente nos seguintes temas: atenção primária à saúde, ensino superior, lesões periapicais e neoplasias de cavidade oral. Atualmente é membro da Sociedade Brasileira de Estomatologia e Patologia Oral.

Gabriel Gomes da Silva, Universidade Federal do Rio Grande do Norte

Graduando em Odontologia pela Universidade Federal do Rio Grande do Norte.

Juliana Campos Pinheiro, Universidade Federal do Rio Grande do Norte

Cirurgiã-Dentista graduada pela Universidade Tiradentes em Sergipe (2010-2015). Mestre em Patologia Oral pela Universidade Federal do Rio Grande do Norte (UFRN) (2016-2018); Doutorado em Ciências Odontológicas (andamento) - área de concentração: Biologia Experimental - UFRN (2018-2022); Membro da Sociedade Brasileira de Estomatologia e Patologia Oral (2016-atualmente).

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Published

02/08/2020

How to Cite

SOUSA, L. C. de .; AMANCIO, A. de M.; SILVA, Érika G. C. da .; OLIVEIRA, F. J. D. de .; GONÇALVES, G. C.; ALMEIDA, D. R. de M. F.; SILVA, G. G. da .; PINHEIRO, J. C. Orofacial findings of congenital generalized lipodystrophy: a systematic review. Research, Society and Development, [S. l.], v. 9, n. 8, p. e903986659, 2020. DOI: 10.33448/rsd-v9i8.6659. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/6659. Acesso em: 23 dec. 2024.

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Vol. 9 No. 8

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Review Article

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Copyright (c) 2020 Juliana Campos Pinheiro, Lucas Cavalcante de Sousa, Amanda de Medeiros Amancio, Érika Giovana Carvalho da Silva, Francisca Jennifer Duarte de Oliveira, Gabriel Coutinho Gonçalves, Dennys Ramon de Melo Fernandes Almeida, Gabriel Gomes da Silva

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