Seropositive HIV diagnosis after oral histoplasmosis: the importance of multi-professional care in health

Authors

DOI:

https://doi.org/10.33448/rsd-v9i9.7839

Keywords:

HIV Seropositivy; Histoplasmosis; Oral manifestations; Diagnosis, oral.

Abstract

Histoplasmosis is a systemic fungal disease, which can manifest with extrapulmonary lesions. Oral lesions are rarely the first manifestation of late histoplasmosis and can represent an important process of immune imbalance. The objective of this work is to present a clinical case of Histoplasmosis with an oral manifestation of a patient who was unaware of her condition with the Human Immunodeficiency Virus (HIV). The patient's main complaint was a painful ulcer in the central region of the tongue present for two months, whose incisional biopsy resulted in the diagnosis of Histoplasmosis. Although referred for medical treatment with an infectologist, the patient had complications resulting from the disease and died after one month. This situation demonstrates the importance of multidisciplinary care in the prevention, diagnosis and treatment of diseases. The correct diagnosis and treatment can be decisive in the prognosis of patients and demonstrates the relevance of the dentist's knowledge about the various systemic diseases that present oral manifestations.

References

Almeida, M. A., Almeida-Silva, F., Guimarães, A. J., Almeida-Paes, R. & Zancopé-Oliveira, R. M. (2019). The occurrence of histoplasmosis in Brazil: A systematic review. International Journal of Infectious Diseases. 86:147-156.

Azar, M. M., & Hage, C. A. (2017). Clinical Perspectives in the Diagnosis and Management of Histoplasmosis. Clinics in Chest Medicine, 38(3), 403-415.

Bongomin, F., Kwizera, R. & Denning, D. (2019). Getting Histoplasmosis on the Map of International Recomendations for Patients with Advanced HIV Disease. Journal of Fungi. 5(3):1-7.

CDC. Center for Disease Control and Prevention. (2018). Available in < https://www.cdc.gov/fungal/diseases/histoplasmosis/index.html> Acess: 02/2020.

Evrard, S., Caprasse, P., Gavage, P., Vasbien, M., Radermacher, J., Hayette, M-P., Sacheli, R., Van Esbroeck, M., Cnops, L., Firre, E., Médart L., Moerman, F. & Minon, J-M. (2018). Disseminated histoplasmosis: case report and review of the literature. Acta Clinica Belgica. 73(5):356-363.

Folk, G. A. & Nelson, B. L. (2017). Oral Histoplasmosis. Head and Neck Pathology. 11:513-516.

Hendren, N., Yek, C., Mull, J. & Curtell, J. B. (2017). Disseminated histoplasmosis presenting as multiple oral ulcers. BMJ Case Report. 2017:bcr2017220364.

Klein, I. P., Martins, M. A. T., Martins, M. D. & Carrard, V. C. (2016). Diagnosis of HIV infection on the basis of histoplasmosis-related oral ulceration. Special Care in Dentistry. 36(2): 99-103.

Nacher, M., Coupplié, P., Epelboin, L., Djossou, F., Demar, M. & Adenis, A. (2020). Disseminated Histoplasmosis: Fighting a neglected killer of patients with advanced HIV disease in Latin America. PLOS Pathogens.16(5):e1008449.

NIH. National Institutes of Health. (2019). Panel on Opportunistic Infections in Adults and Adolescents with HIV. Guidelines for the prevention and treatment of opportunistic infections in adults and adolescents with HIV: recommendations from the Centers for Disease Control and Prevention, the National Institutes of Health, and the HIV Medicine Association of the Infectious Diseases Society of America. Available in <http://aidsinfo.nih.gov/contentfiles/lvguidelines/adult_oi.pdf>. Acess: 08/02/2020.

Oliveira, D. G., Felix, K. C. S., Farias, J. V. C. & Farias, I. C. C. (2020). Clinical and laboratory aspects of histoplasmosis: a bibliographic review. Research, Society and Development. 9(7):1-26, e476974353.

Telles, D. R., Karki, N. & Marshall, M. W. (2017). Oral Fungal Infections. Dental Clinics of North America. 61(2):319-349.

Valle, A. C .F., Moreira, L. C., Almeida-Paes, R., Moreira, J. S., Pizzini, C. V., Muniz, M. M. & Zancopé-Oliveira, R.M. (2006). Chronic Disseminated Histoplasmosis with lesions restricted to the mouth: case report. Revista do Instituto de Medicina Tropical São Paulo. 48(2):113-6.

Vidya, K. M., Rao, U. K., Nittayananta, W., Liu, H. & Owotade, F. J. (2016). Oral mycosis and other opportunistic infections in HIV: therapy and emerging problems – a workshop report. Oral Diseases. 22 (1):158-165.

Wheat, L. J., Azar, M. M., Bahr, N. C., Spec, A., Relich, R. F. & Hage, C. (2016). Histoplasmosis. Infectious Disease Clinics of North America. 30(1):207-227.

Downloads

Published

04/09/2020

How to Cite

Seixas, G. F. ., Spadrizani, A. F., Gregorio, D., Poleti, M. L., & Fernandes , T. M. F. (2020). Seropositive HIV diagnosis after oral histoplasmosis: the importance of multi-professional care in health. Research, Society and Development, 9(9), e716997839. https://doi.org/10.33448/rsd-v9i9.7839

Issue

Section

Health Sciences