Management of nausea and vomiting symptoms induced by chemotherapy: an integrative review




Chemotherapy; Nausea; Vomiting; Oncology nursing.


Chemotherapy is one of the therapies available to cancer patients undergoing neoadjuvant, adjuvant or palliative treatment. Among the most prevalent symptoms, there is nausea and vomiting induced by chemotherapy, being considered side effects, which cause fragility and suffering to some patients. The study aims to know the measures found for the control of nausea and vomiting induced by chemotherapy in adult cancer patients. It is an integrative review, of a qualitative nature, whose analysis will be of an exploratory approach. The study consisted of eight articles selected from the Pubmed and Scielo databases between 2015 and 2020. It was noted that despite advances in pharmacological and non-pharmacological therapies and the provision of standard clinical guidelines for the effective management of nausea and vomiting induced by chemotherapy, patients continue to experience these symptoms in most cases. The need to intensify research on non-pharmacological strategies to optimize the management of this problem was evidenced, since controlling the side effects of a chemotherapy treatment provides excellence in care and quality of life for patients.


Adel N. (2017). Overview of chemotherapy-induced nausea and vomiting and evidence-based therapies. Am J Manag Care, 23(14 Suppl):259–265.

Borges, D. O., Freitas, K. A. B. S., Minicucci, E. M., & Popim, R. C. (2020). Benefícios do gengibre no controle de náuseas e vômitos induzidos por quimioterapia. Revista Brasileira de Enfermagem, 73 (2), e20180903.

Brasil. Instituto Nacional de Câncer (INCA). (2011). Estimativa 2012: incidência de câncer no Brasil. Rio de Janeiro: Inca. Recuperado de Estimativa_2012__incidencia_de_cancer_no_Brasil_/56>.

Brasil. Ministério da Saúde. Instituto Nacional de Câncer (Inca). (2019). O que é câncer? Rio de Janeiro: Inca. Recuperado de: <>.

Fernández-Ortega P., Caloto, M., Chirveches E., Marquilles R., Francisco J., Quesada A., ... & Llombart-Cussac, A. (2012). Chemotherapy-induced nausea and vomiting in clinical practice: impact on patients’ quality of life. Supportive Care in Cancer. 20(12):3141–3148. doi: 10.1007 / s00520-012-1448-1.

França, A. C., Rodrigues, A. B., Aguiar, M. I. F., Silva, R. A., Freitas, F. M. C., & Melo, G. A. A. (2019). Telenursing for the control of chemotherapy-induced nausea and vomiting: a randomized clinical trial. Texto & Contexto - Enfermagem, 28, e20180404.

Faria, L. P., & Fagundes, T. R. (2020). Chemotherapic extravasation: the nurse’s role in oncological emergency. Research, Society and Development, 9(10), e9719109400.

Gao, L., Chen, B., Zhang, Q., Zhao, T., Li, B., Sha, T., & Guo, Y. (2016). Acupuncture with different acupoint combinations for chemotherapy-induced nausea and vomiting: study protocol for a randomized controlled trial. BMC complementary and alternative medicine, 16(1), 441. doi: 10.1186 / s12906-016-1425-1.

Hernandez, T., Mazzarello, S., Terry, N., Dranitsaris, G., Hutton, B., Smith, S., & Clemons, M. (2015). Defining optimal control of chemotherapy-induced nausea and vomiting—based on patients’ experience. Supportive Care in Cancer, 23(11):3341–3359. doi: 10.1007 / s00520-015-2801-y.

Instituto Nacional de Câncer (Inca). (2019). Estimativa 2020: incidência de câncer no Brasil / Instituto Nacional de Câncer José Alencar Gomes da Silva. Rio de Janeiro: INCA. Recuperado de: < document//e stimativa-2020-incidencia-de-cancer-no-brasil.pdf>.

James, N. (2015). Reviewing current and emerging antiemetics for chemotherapy-induced nausea and vomiting prophylaxis. Hospital Practice, 43(4):226–234. doi: 10.1080 / 21548331.2015.1077095.

Janelsins, C., Tejani, A., Kamen, C., Peoples, A., & Mustian, R. (2013). Current pharmacotherapy for chemotherapy-induced nausea and vomiting in cancer patients. Expert Opinion on Pharmacotherapy, 14(6), 757–766. doi: 10.1517 / 14656566.2013.776541.

Li, X., Qin, Y., Liu, W., Zhou, X. Y., Li, Y. N., & Wang, L. Y. (2018). Efficacy of Ginger in Ameliorating Acute and Delayed Chemotherapy-Induced Nausea and Vomiting Among Patients with Lung Cancer Receiving Cisplatin-Based Regimens: A Randomized Controlled Trial. Integrative cancer therapies, 17(3), 747–754. doi: 10.1177 / 1534735417753541.

Liau, C., Chu, M., Liu, H., Deuson, R., Lien, J., & Chen, J. (2015). Incidence of chemotherapy-induced nausea and vomiting in Taiwan: physicians’ and nurses’ estimation vs. patients’ reported outcomes. Support Care Cancer, 13:277–286. doi: 10.1007 / s00520-005-0788-5.

Moradian, S., & Howell, D. (2015). Prevention and management of chemotherapy-induced nausea and vomiting. International Journal of Palliative Nursing, 21(5):216–224. doi: 10.12968 / ijpn.2015.21.5.216.

Pinto, I. F., Campos, C. J. G., & Siqueira, C. (2018). Investigação qualitativa: perspetiva geral e importância para as ciências da nutrição. Acta Portuguesa de Nutrição, (14), 30-34. |

Silva, G. J., Fonseca, M. S., Rodrigues, A. B., Oliveira, P. P., Brasil, D. R. M., & Moreira, M. M. C. (2014). Utilização de experiências musicais como terapia para sintomas de náusea e vômito em quimioterapia. Revista Brasileira de Enfermagem, 67(4), 630-636.

Smith, L. A., Azariah, F., Lavender, V. T., Stoner, N. S., & Bettiol, S. (2015). Cannabinoids for nausea and vomiting in adults with cancer receiving chemotherapy. The Cochrane database of systematic reviews, 2015(11), CD009464. doi: 10.1002 / 14651858.CD009464.pub2.

Sommariva, S., Pongiglione, B., & Tarricone, R. (2016). Impact of chemotherapy-induced nausea and vomiting on health-related quality of life and resource utilization: A systematic review. Critical Reviews in Oncology/Hematology, 99(3):13–36. doi: 10.1016 / j.critrevonc.2015.12.001.

Souza, M. T., Silva, M. D., & Carvalho, R. (2010). Revisão integrativa: o que é e como fazer. Einstein, 8(1), 102-106. DOI: 10.1590/s1679-45082010rw1134.

Vidall C., Fernández-Ortega P., Cortinovis D., Jahn P., Amlani B., & Scotté F. (2015). Impact and man-agement of chemotherapy/radiotherapy-induced nausea and vomiting and the perceptual gap between oncologists/oncology nurses and patients: a cross-sectional multinational sur-vey. Support Care Cancer. 23(11), 3297-5. doi: 10.1007 / s00520-015-2750-5.

Wakiuchi, J., Marcon, S. S., Oliveira, D. C., & Sales, C. A. (2019). A quimioterapia sob a ótica da pessoa com câncer: uma análise estrutural. Texto & Contexto - Enfermagem, 28, e20180025.



How to Cite

Duarte, A. dos S., Monteiro, D. da R., Souza, T. de C., & Oliveira, T. da S. (2020). Management of nausea and vomiting symptoms induced by chemotherapy: an integrative review. Research, Society and Development, 9(11), e1859119723.



Health Sciences