Intramucosal oral nevus: case report




Mouth; Pigmentation; Diagnosis; Nevus.


The patient presented with the main complaint of "a stain on my gums has appeared". Anamnesis and extraoral physical examination showed no change. In the intraoral physical examination, a dark lesion located in the attached gingiva was observed. An excisional biopsy procedure was proposed to investigate the diagnostic possibility of early oral melanoma. The result of the histopathological examination ruled out the diagnostic hypothesis of the malignant lesion and enabled the definitive diagnosis of the intramucosal oral nevus. The patient has been in follow-up for two years with no signs of recurrence. Pigmented oral lesions have an etiological variety and may also have similar clinical characteristics, especially between oral melanocytic nevi and oral melanoma. Therefore, to obtain a safe diagnosis and, consequently, to establish the most appropriate treatment for these lesions, it is important to make an association between anamnesis and clinical and histopathological examination.


Buchner, A., Merrell, P. W., Carpenter, W. M. (2004). Relative frequency of solitary melanocytic lesions of the oral mucosa. J oral pathol med, 33(9), 550-7.

Ferreira, L., Jham, B., Assi, R., Readinger, A., Kessler, H. P. (2015). Oral melanocytic nevi: a clinicopathologic study of 100 cases. Oral surg oral med oral pathol oral radiol, 120(3), 358-67.

Freitas, D. A., Bonan, P. R., Sousa, A.A., Pereira, M. M., Oliveira, S.M., Jones, K.M. (2015). Intramucosal nevus in the oral cavity. J Contemp Dent Pract, 16(1), 74-6.

Gondak, R. O., Silva-Jorge, R., Jorge, J., Lopes, M. A., Vargas, P. A. (2012). Oral pigmented lesions: Clinicopathologic features and review of the literature. Med oral patol oral cir bucal, 17(6), e919-24.

Kauzman, A., Pavone, M., Blanas, N., Bradley, G. (2004). Pigmented lesions of the oral cavity: review, differential diagnosis, and case presentations. J Can Dent Assoc, 70(10), 682-3.

Lambertini, M., Patrizi, A., Fanti, P. A., Melotti, B., Caliceti, U., Magnoni, C., Misciali, C., Baraldi, C., Ravaioli, G. M., Dika, E. (2017). Oral melanoma and other pigmentations: when to biopsy? J Eur Acad Dermatol Venereol, 32(2), 209-214.

Meleti, M., Mooi, W. J., Casparie, M. K., van der Waal, I. (2007). Melanocytic nevi of the oral mucosa – no evidence of increased risk for oral malignant melanoma: an analysis of 119 cases. Oral oncol, 43(10), 976-981.

Müller, S. (2010). Melanin‐associated pigmented lesions of the oral mucosa: presentation, differential diagnosis, and treatment. Dermatol therapy, 23(3), 220-229.

Natarajan, E. Black and Brown Oro-facial Mucocutaneous Neoplasms. (2019). Head Neck Pathol, 13(1), 56-70.

Pereira, AS et al. (2018). Metodologia da pesquisa científica. [e-book]. Santa Maria. Ed. UAB/NTE/UFSM.

Tavares, T. S., Meirelles, D. P., de Aguiar, M. C. F., Caldeira, P. C. (2018). Pigmented lesions of the oral mucosa: A cross‐sectional study of 458 histopathological specimens. Oral dis, 24(8), 1484-1491.

Vasconcelos, R. G., Moura, I. S., Medeiros, L. K. S., de Melo, D. S., Vasconcelos, M. G. (2014). As principais lesões enegrecidas da cavidade oral. Rev cuba estomatol, 51(2).



How to Cite

Fernandes Santana, S., Santos , E. G. F. dos, Ávila, E. C., Pimentel , L. M. C., & Santos , L. C. O. dos. (2020). Intramucosal oral nevus: case report. Research, Society and Development, 9(11), e2409119815.



Health Sciences