Larvicidal activity opposite Aedes aegypti of the essential oil of the dry leaves of Syzygium cumini (L.) Skeels (Myrtaceae)

Authors

DOI:

https://doi.org/10.33448/rsd-v9i11.9967

Keywords:

Larvicidal; Essential oil; Syzygium cumini.

Abstract

This study aimed to evaluate the larvicidal activity of essential oil (EO) extracted from the dry leaves of Syzygium cumini (L.) Skeels. The hydrodistillation technique was used for EO extraction in a modified Clevenger extractor system. The chemical constituents were obtained by Gas Chromatography coupled to mass spectrometry (GC/MS). For larvicidal activity, Larvae of Aedes aegypti were submitted to OE solutions at concentrations of 10-100 mgL-1,where larvae mortality was evaluated and LC50 was determined. Isocaryofylene was quantified as the majority in THE. The action of the EO was observed as larvicidal where CL50 of 29.58 mg L-1 was determined. The results obtained allowed us to conclude that the studied OE presented efficient larvicidal activity against the larvae of Aedes aegypti, being important and encouraged its use and application.

Author Biographies

Paulo Victor Serra Rosa, Universidade Federal do Maranhão

Biomédico (UNINASSAU) e Pesquisador (UFMA).

Ari Pereira de Araújo Neto, Faculdade Uninassau

Mestre em Biotecnologia

Wilma Karlla dos Santos Farias, Universidade Federal do Maranhão

Mestrado em Ciências da Saúde

Francilidia Oliveira Vitorino de Assunção Conceição, Universidade Federal do Maranhão

Mestrando em Odontologia na área de Saúde Coletiva

Liane Batista da Cruz Soares, Universidade Federal do Maranhão

Mestra em Gestão de Programas e serviços de Saúde

Maria Gizelda Gomes Lages, Universidade Federal do Piauí

Especialista em saúde materna, neonatal e do lactente.

Feliciana Santos Pinheiro, Universidade Federal do Maranhão

Doutora em Pediatria

Ricardo Teixeira de Sousa, LabMed e BioSaude

Especialista em Citologia Clínica

Ione Rocha Neves, Universidade Federal do Maranhão

Especialização em Educação Profissional na Área de Saúde: Enfermagem.
Especialização em Saúde da Família - Clínica na Atenção Primária.
Especialização em Enfermagem Clínico-cirúrgica na modalidade Residência.

Thayson Rodrigues Lopes, Universidade Federal do Maranhão

Mestre em Biotecnologia

Victor Elias Mouchrek Filho , Universidade Federal do Maranhão

Doutorado em Química (USP).

References

Ayyanar, M., Subash-Babu, P., & Ignacimuthu, S. (2013). Syzygium cumini (L.) Skeels., a novel therapeutic agent for diabetes: folk medicinal and pharmacological evidences. Complementary Therapies in Medicine, 21(3), 232-243.

Ayyanar, M., & Subash-Babu, P. (2012). Syzygium cumini (L.) Skeels: A review of its phytochemical constituents and traditional uses. Asian Pacific journal of tropical biomedicine, 2(3), 240-246.

Braz-Filho, R. (1994). Química de produtos naturais: importância, interdisciplinaridade, dificuldades e perspectivas. A peregrinação de um pacatubano. Química Nova, 17(5), 405-445.

Chantraine, J. M., Laurent, D., Ballivian, C., Saavedra, G., Ibañez, R., & Vilaseca, L. A. (1998). Insecticidal activity of essential oils on Aedes aegypti larvae. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 12(5), 350-354.

Cheng, S. S., Liu, J. Y., Tsai, K. H., Chen, W. J., & Chang, S. T. (2004). Chemical composition and mosquito larvicidal activity of essential oils from leaves of different Cinnamomum osmophloeum provenances. Journal of Agricultural and Food Chemistry, 52(14), 4395-4400.

Chhikara, N., Kaur, R., Jaglan, S., Sharma, P., Gat, Y., & Panghal, A. (2018). Bioactive compounds and pharmacological and food applications of Syzygium cumini–a review. Food & function, 9(12), 6096-6115.

Corrêa, T. C. V. (2018). Jambolão (Syzygium cumini L): produção do óleo volátil e análise cromatográfica em CG/EM. In 24º Congresso de Iniciação Científica da Unb e 15º do DF.

Debbarma, J., Kishore, P., Nayak, B. B., Kannuchamy, N., & Gudipati, V. (2013). Antibacterial activity of ginger, eucalyptus and sweet orange peel essential oils on fish‐borne bacteria. Journal of Food Processing and Preservation, 37(5), 1022-1030.

Dias, C. N., Rodrigues, K. A., Carvalho, F. A., Carneiro, S. M., Maia, J. G., Andrade, E. H., & Moraes, D. F. (2013). Molluscicidal and leishmanicidal activity of the leaf essential oil of Syzygium cumini (L.) SKEELS from Brazil. Chemistry & biodiversity, 10(6), 1133-1141.

Faria, A. F., Marques, M. C., & Mercadante, A. Z. (2011). Identification of bioactive compounds from jambolão (Syzygium cumini) and antioxidant capacity evaluation in different pH conditions. Food chemistry, 126(4), 1571-1578.

Forattini, O. (1962). Entomologia medica vol. I Faculdade de Higiene e Saude Publica. Sao Paulo, Brazil. pp.

Govindarajan, M., Sivakumar, R., Rajeswari, M., & Yogalakshmi, K. (2012). Chemical composition and larvicidal activity of essential oil from Mentha spicata (Linn.) against three mosquito species. Parasitology research, 110(5), 2023-2032.

Murthy, J. M., & Rani, P. U. (2009). Biological activity of certain botanical extracts as larvicides against the yellow fever mosquito, Aedes aegypti L. J Biopest, 2(1), 72-6.

Kaushik, R., & Saini, P. (2009). Screening of some semi-arid region plants for larvicidal activity against Aedes aegypti mosquitoes. J Vector Borne Dis, 46, 244-246.

Mir, Q. Y., Ali, M., & Alam, P. (2009). Lignan derivatives from the stem bark of Syzygium cumini (L.) Skeels. Natural product research, 23(5), 422-430.

Mohamed, A. A., Ali, S. I., & El-Baz, F. K. (2013). Antioxidant and antibacterial activities of crude extracts and essential oils of Syzygium cumini leaves. Plos one, 8(4), e60269.

Nishandhini, S., Sudha, V., Mallavarapu, G. R., & Murugan, R. (2015). Chemical Compositions, α-amylase inhibitory and antioxidant activities of the essential oils from unripe fruit pulp and leaves of Syzygium cumini. Int. J. Pharm. Pharm. Sci, 7(2), 515-519.

Pizzi, M. (1950). Sampling variation of the fifty per cent end-point, determined by the ReedMuench (Behrens) method. Human biology, 22(3), 151-190.

Reed, L. J., & Muench, H. (1938). A simple method of estimating fifty per cent endpoints. American journal of epidemiology, 27(3), 493-497.

Ruggiero, A. D. A. (2004). Estudo farmacognóstico do jambolão Syzygium cumini (L.) Skeels Myrtaceae (Doctoral dissertation, Universidade de São Paulo).

Saroj, A., Pragadheesh, V. S., Yadav, A., Singh, S. C., Samad, A., Negi, A. S., & Chanotiya, C. S. (2015). Anti-phytopathogenic activity of Syzygium cumini essential oil, hydrocarbon fractions and its novel constituents. Industrial Crops and Products, 74, 327-335.

Schenkel, E. P., Gosmann, G., & Petrovick, P. R. (2003). Produtos de origem vegetal e o desenvolvimento de medicamentos. Farmacognosia: da planta ao medicamento, 5, 371-400.

Shafi, P. M., Rosamma, M. K., Jamil, K., & Reddy, P. S. (2002). Antibacterial activity of Syzygium cumini and Syzygium travancoricum leaf essential oils. fitoterapia, 73(5), 414-416.

Silva, V. P., Alves, C. C. F., Miranda, M. L. D., Bretanha, L. C., Balleste, M. P., Micke, G. A., ... & Tavares, D. C. (2018). Chemical composition and in vitro leishmanicidal, antibacterial and cytotoxic activities of essential oils of the Myrtaceae family occurring in the Cerrado biome. Industrial Crops and Products, 123, 638-645.

Singh, J. P., Kaur, A., Shevkani, K., & Singh, N. (2015). Influence of jambolan (S yzygium cumini) and xanthan gum incorporation on the physicochemical, antioxidant and sensory properties of gluten‐free eggless rice muffins. International journal of food science & technology, 50(5), 1190-1197.

Silva, W. J. d. (2006). Atividade larvicida do óleo essencial de plantas existentes no estado de Sergipe contra Aedes aegypti Linn.

Srivastava, S., & Chandra, D. (2013). Pharmacological potentials of Syzygium cumini: a review. Journal of the Science of Food and Agriculture, 93(9), 2084-2093.

Stefanello, M. É. A., Pascoal, A. C., & Salvador, M. J. (2011). Essential oils from neotropical Myrtaceae: chemical diversity and biological properties. Chemistry & biodiversity, 8(1), 73-94.

Xavier, L. D. (2019). Avaliação da atividade antifúngica do óleo essencial de Syzygium cumini (Bachelor's thesis, Universidade Tecnológica Federal do Paraná).

Veigas, J. M., Narayan, M. S., Laxman, P. M., & Neelwarne, B. (2007). Chemical nature, stability and bioefficacies of anthocyanins from fruit peel of Syzygium cumini Skeels. Food Chemistry, 105(2), 619-627.

Zara, A. L. D. S. A., Santos, S. M. D., Fernandes-Oliveira, E. S., Carvalho, R. G., & Coelho, G. E. (2016). Estratégias de controle do Aedes aegypti: uma revisão. Epidemiologia e Serviços de Saúde, 25, 391-404.

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Published

26/11/2020

How to Cite

EVERTON, G. O.; ROSA, P. V. S. .; ARAÚJO NETO, A. P. de .; FARIAS, W. K. dos S. .; CONCEIÇÃO, F. O. V. de A. .; SOARES, L. B. da C. .; LAGES, M. G. G. .; PINHEIRO, F. S. .; SOUSA, R. T. de .; NEVES, I. R. .; LOPES, T. R. .; MOUCHREK FILHO , V. E. . Larvicidal activity opposite Aedes aegypti of the essential oil of the dry leaves of Syzygium cumini (L.) Skeels (Myrtaceae). Research, Society and Development, [S. l.], v. 9, n. 11, p. e5529119967, 2020. DOI: 10.33448/rsd-v9i11.9967. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/9967. Acesso em: 22 nov. 2024.

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Section

Health Sciences