Large dimension odontogenic keratocysts: case report

Authors

DOI:

https://doi.org/10.33448/rsd-v9i12.11426

Keywords:

Keratocyst; Odontogenic; Recidive; Cyst; Growth.

Abstract

Odontogenic keratocyst (OKC) is a lesion which origin is the dental epithelium, it has a predilection for presenting itself in the posterior portion of the mandible and is considered one of the most common lesions within odontogenic cysts. The following study presents a case of Odontogenic Keratocyst of a large dimension. A female patient presents with inflammatory symptoms at the level of the jaw. In the intraoral physical examination a palpation test was performed and together with radiographic examinations, in which a multilocular radiolucent image of 8x3 cm was determined. Subsequently, a biopsy was performed and the histology was compatible with Odontogenic Keratocyst. This article reviews the etiopathogenesis, clinical, radiographic, histopathological, immunohistochemical and treatment; with the aim of describing the importance of this lesion due to its ability to reach large dimensions and present high recurrence. Therefore, it is important to make a correct diagnosis that allows to establish an adequate treatment plan for this lesion.

References

Bhargava, D., Deshpande, A., & Pogrel, M. A. (2012). Keratocystic odontogenic tumour (KCOT)—a cyst to a tumour. Oral and maxillofacial surgery, 16(2), 163-170.

Cohen, J. M, & Ziccardi, V. B. (2018). Use of Virtual Surgical Planning as an Adjunct for Enucleation of Multiple Recurrent Odontogenic Keratocysts: Case Report. Journal of Oral and Maxillofacial Surgery, 76(10), 2137. e2131-2137. e2136.

Fajardo Ortiz, L. V, & Peña Vega, C. P. Frequency of Odontogenic Cysts in Patients of the National University of Colombia Dental School.

Gupta, D, Gupta, M, & Borle, R. (1985). Pan-mandibular keratocyst with eosinophilia. International journal of oral surgery, 14(3), 311-313.

Jaeger, F., de Noronha, M. S, Silva, M. L. V, Amaral, M. B. F, Grossmann, S. d. M. C., Horta, M. C. R, & Mesquita, R. A. (2017). Prevalence profile of odontogenic cysts and tumors on Brazilian sample after the reclassification of odontogenic keratocyst. Journal of Cranio-Maxillofacial Surgery, 45(2), 267-270.

Johnson, N. R., Gannon, O. M., Savage, N. W, & Batstone, M. D. (2014). Frequency of odontogenic cysts and tumors: a systematic review. Journal of investigative and clinical dentistry, 5(1), 9-14.

Kaczmarzyk, T., Kisielowski, K., Koszowski, R., Rynkiewicz, M., Gawełek, E., Babiuch, K, & Drozdzowska, B. (2018). Investigation of clinicopathological parameters and expression of COX-2, bcl-2, PCNA, and p53 in primary and recurrent sporadic odontogenic keratocysts. Clinical oral investigations, 22(9), 3097-3106.

Kahraman, D., Gunhan, O, & Celasun, B. (2018). A series of 240 odontogenic keratocysts: Should we continue to use the terminology of ‘keratocystic odontogenic tumour’for the solid variant of odontogenic keratocyst? Journal of Cranio-Maxillofacial Surgery, 46(6), 942-946.

Khan, A. A., Al Qahtani, S., Dawasaz, A. A., Saquib, S. A., Asif, S. M., Ishfaq, M, . & Ibrahim, M. (2019). Management of an extensive odontogenic keratocyst: A rare case report with 10-year follow-up. Medicine, 98(51).

Kshirsagar, R. A., Bhende, R. C., Raut, P. H., Mahajan, V., Tapadiya, V. J, & Singh, V. (2019). Odontogenic keratocyst: Developing a protocol for surgical intervention. Annals of Maxillofacial Surgery, 9(1), 152.

Ochsenius Rondanelli, G., Escobar López, E., Godoy Rojas, L, & Peñafiel, C. (2007). Quistes odontogénicos: Análisis de 2.944 casos en Chile.

Pereira, A., Shitsuka, D., Parreira, F, & Shitsuka, R. (2018). Metodologia da pesquisa científica.[e-book]. Santa Maria. Ed.

Pittl, T. L., Meier, M., Hakl, P, Sutter, W, & Turhani, D. (2017). Long-term observation of a large keratocystic odontogenic tumour of the mandible treated by a single enucleation procedure: A case report and literature review. International Journal of Surgery Case Reports, 34, 119-122.

Polak, K., Jędrusik-Pawłowska, M., Drozdzowska, B, & Morawiec, T. (2019). Odontogenic keratocyst of the mandible: A case report and literature review. Dental and Medical Problems, 56(4), 433-436.

Portes, J., Cunha, K. S. G., da Silva, L. E., da Silva, A. K. F., Conde, D. C, & Junior, A. S. (2020). Computerized Evaluation of the Immunoexpression of Ki-67 Protein in Odontogenic Keratocyst and Dentigerous Cyst. Head and neck pathology, 14(3), 598-605.

Sansare, K., Raghav, M., Mupparapu, M., Mundada, N., Karjodkar, F. R., Bansal, S, & Desai, R. (2013). Keratocystic odontogenic tumor: systematic review with analysis of 72 additional cases from Mumbai, India. Oral surgery, oral medicine, oral pathology and oral radiology, 115(1), 128-139.

Santana, O, & Denisse, M. (2016). Patologías asociadas a dientes retenidos encontradas en tomografía Cone Beam entre Centro Radiológico Guayaquil-2015.

Silva, Y. S., Stoelinga, P. J, & Graça Naclério-Homem, M. (2019). The presentation of odontogenic keratocysts in the jaws with an emphasis on the tooth-bearing area: a systematic review and meta-analysis. Oral and maxillofacial surgery, 1-15.

Sigua-Rodriguez, E. A., Goulart, D. R., Sverzut, A., Asprino, L, & de Moraes, M. (2019). Is surgical treatment based on a 1-step or 2-step protocol effective in managing the odontogenic keratocyst? Journal of Oral and Maxillofacial Surgery, 77(6), 1210. e1211-1210. e1217.

Vallejo-Rosero, K. A., Camolesi, G. V., de Sá, P. L. D, & Bernaola-Paredes, W. E. (2020). Conservative management of odontogenic keratocyst with long-term 5-year follow-up: Case report and literature review. International Journal of Surgery Case Reports, 66, 8-15.

Villarroel-Dorrego, M, & Rondón, N. L. Prevalencia de quistes odontogénicos en población venezolana.

Wright, J. M, & Vered, M. (2017). Update from the 4th edition of the World Health Organization classification of head and neck tumours: odontogenic and maxillofacial bone tumors. Head and neck pathology, 11(1), 68-77.

Published

28/12/2020

How to Cite

ALMACHE, M. E. C. .; CALLE, M. F. T. .; GAVILANES, M. P. P. .; YAGUANA, D. V. C. .; CAMPOVERDE, J. D. C. . Large dimension odontogenic keratocysts: case report. Research, Society and Development, [S. l.], v. 9, n. 12, p. 43091211426, 2020. DOI: 10.33448/rsd-v9i12.11426. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/11426. Acesso em: 13 nov. 2024.

Issue

Section

Health Sciences