Uso pré-operatório de gabapentina na redução da dor em cirurgias abertas com anestesia local para síndrome do túnel do carpo bilateral idiopática

Autores

DOI:

https://doi.org/10.33448/rsd-v10i4.14506

Palavras-chave:

Síndrome do Túnel do Carpo; Período Pré-Operatório; Adjuvantes Anestésicos; Gabapentina.

Resumo

Esse artigo tem por objetivo avaliar o uso pré-operatório da gabapentina no controle da dor intra e pós-operatória em indivíduos com síndrome do túnel do carpo (STC) bilateral idiopática. Foi realizado um estudo prospectivo, randomizado e duplo cego com 45 indivíduos, 23 que receberam tratamento (gabapentina 600 mg) e 22 que receberam placebo (controle), os quais se submeteram a uma abordagem cirúrgica aberta em uma das mãos, sob anestesia local, com grau severo de STC. Informações relacionadas ao perfil dos indivíduos, segurança do procedimento cirúrgico, histórico de dor, efeitos adversos, dormência e medicamentos utilizados foram coletadas ao longo do procedimento, durante 14 dias, para serem avaliadas por modelos Generalized Estimated Equations (GEE) e Generalized Linear Mixed Models (GLMM). Os grupos de tratamento e de controle mostraram-se homogêneos em termos de perfil e no que concerne aos dados do procedimento cirúrgico. Os pacientes que utilizaram gabapentina 600 mg atribuíram uma melhor avaliação intraoperatória (d = 0,655) durante a anestesia (d = 0,854) e na primeira noite de sono (d = 1,323) e maior grau de satisfação com a cirurgia após 14 dias (d = 1,091). O grupo de tratamento percebeu uma melhora na dor da mão operada no período de 24 horas (r = 0,34; IC95%: 0,223-0,457) e no período do seguimento de 14 dias (r = 0,412; IC95%: 0,217-0,608). Esses resultados não foram impactados pelos medicamentos utilizados e se mantiveram consistentes ao longo do tempo. O uso de gabapentina 600 mg em dose única no pré-operatório mostrou-se seguro e eficaz na redução da dor no pós-operatório, com melhora percebida pelo paciente.

Biografia do Autor

Sergio Murilo Georgeto, University of Northern Paraná

Graduate Programme in Rehabilitation Sciences

Department of Neurosurgery, Santa Casa de Londrina, Londrina, PR, Brazil.

 

Rodrigo Antônio Carvalho Andraus, University of Northern Paraná

Graduate Programme in Rehabilitation Sciences

Ovídia Ignês Pires, University of Northern Paraná

Graduate Programme in Rehabilitation Sciences

Eros de Oliveira Junior, University of Northern Paraná

Group of Studies and Research in Physical Exercise and Rehabilitation (GEPEFIR)

Karen Barros Parron Fernandes, University of Northern Paraná

Graduate Programme in Rehabilitation Sciences

Institute of Education, Research ad Innovation of Imandade da Santa Casa de Londrina (IEPI-ISCAL)

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22/04/2021

Como Citar

GEORGETO, S. M.; ANDRAUS, R. A. C.; PIRES, O. I.; OLIVEIRA JUNIOR, E. de; FERNANDES, K. B. P. Uso pré-operatório de gabapentina na redução da dor em cirurgias abertas com anestesia local para síndrome do túnel do carpo bilateral idiopática. Research, Society and Development, [S. l.], v. 10, n. 4, p. e54410414506, 2021. DOI: 10.33448/rsd-v10i4.14506. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/14506. Acesso em: 3 abr. 2025.

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