The silver diamine fluoride in the management of early childhood caries during COVID-19 pandemic
Keywords:Child, Preschool; Dental Caries; Cariostatic agents; Severe Acute Respiratory Syndrome; SARS virus.
Objective: To address aspects of clinical interest related to the use of silver diamine fluoride (SDF) in the management of early childhood caries (ECC) during the COVID-19 pandemic. Methods: The search for the literature review was carried out in the PubMed database. The descriptors were chosen according to their importance in delimiting the theme and the literature synthesis considered the topics: (1) clinical effectiveness, indications, and limits of SDF, and (2) clinical use of SDF in COVID-19 context. Results: COVID-19 pandemic affects all sectors of society, and especially for pediatric dentists it imposes challenges in a scenario of difficult decision-making and liable of contamination. The treatment of caries disease with SDF gains an important connotation due to its effectiveness in the arrestment and prevention of caries lesions, safety, ease use, and low cost. It is considered a minimally invasive therapy that dispenses the use of rotary instruments (which have a high potential for contamination via aerosol dispersion) and reduces complications such as pulpitis and tooth loss and, therefore, the number of appointments. Besides, SDF is an option in which there is greater behavioral acceptance by the child. As a negative point, SDF can cause aesthetic dissatisfaction due to the darkening of the affected tooth surface. Conclusion: The caries lesions control in children with ECC using SDF, during the COVID-19 pandemic, is an effective, inexpensive, and easy to apply option. In addition, it offers a lower contamination risk by the coronavirus.
Alharbi, A., Alharbi, S., & Alqaidi S (2020). Guidelines for dental care provision during the COVID-19 pandemic. Saudi Dent J. 32(4),181-6.
Aquino, E. M. L., Silveira, I. H., Pescarini, J. M., et al (2020). Social distancing measures to control the COVID-19 pandemic: potential impacts and challenges in Brazil. Cien Saude Colet, 25(suppl 1), 2423-46.
Bavel, J. J. V., Baicker, K., Boggio, O. S., et al (2020). Using social and behavioural science to support COVID-19 pandemic response. Nat Hum Behav, 4(5), 460-71.
Braga, M. M., Mendes, F. M., De Benedetto, M. S., & Imparato, J. C. (2009). Effect of silver diammine fluoride on incipient caries lesions in erupting permanent first molars: a pilot study. Journal of Dentistry for Children, 76(1),28-33.
Brasil 2020. Agência Nacional de Vigilância Sanitária (ANVISA), Nota Técnica GVIMS/GGTES/ANVISA Nº 04/2020. Brasília.
Casamassimo, P. S., Thikkurissy, S., Edelstein, B. L., & Maiorini E (2009). Beyond the dmft. The human and economic cost of early childhood caries. J Am Dent Assoc, 140, 650-7.
Chibinski, A. C., Wambier, L. M., Feltrin, J., Loguercio, A. D., Wambier, D. S., & Reis (2017). A. Silver diamine fluoride has efficacy in controlling caries progression in primary teeth: a systematic review and meta-analysis. Caries Res, 51(5), 527-4.
Chu, C. H., Lo, E. C. M., & Lin, H. C. (2002). Effectiveness of Silver Diamine Fluoride and Sodium Fluoride Varnish in Arresting Dentin Caries in Chinese Pre-school Children. J Dent Res, 81(11), 767-770.
Chu, C. H., & Lo, E. C. M. (2008). Promoting caries arrest in children with silver diamine fluoride: a review. Oral Health Prev Dent, 6(4), 315-321.
Chu, C. H., Lo, E. C. M., & Lin, H. C. (2002). Effectiveness of Silver Diamine Fluoride and Sodium Fluoride Varnish in Arresting Dentin Caries in Chinese Pre-school Children. J Dent Res, 81(11), 767-70.
Clemens, J., Gold, J., & Chaffin J (2018). Effect and acceptance of silver diamine fluoride treatment on dental caries in primary teeth. J Public Health Dent, 78(1), 63-68.
Contreras, V., Toro, M. J., & Elías-Boneta, A. R (2017). Encarnación-Burgos A. Effectiveness of silver diamine fluoride in caries prevention and arrest: a systematic literature review. Gen Dent, 65(3), 22-29.
Corrêa-Faria, P., Viana, K. A., Raggio, D. P., Hosey, M. T., & Costa, L. R (2020). Recommended procedures for the management of early childhood caries lesions - a scoping review by the Children Experiencing Dental Anxiety: Collaboration on Research and Education (CEDACORE). BMC Oral Health, 20(1), 75.
de Almeida, L. F., Cavalcanti, Y. W., & Valenca, A. (2011). In vitro antibacterial activity of silver diamine fluoride in different concentrations. Acta Odontol Latinoam, 24(2), 127-131.
Duangthip, D., Chu, C. H., & Lo, E. C. (2016). A randomized clinical trial on arresting dentine caries in preschool children by topical fluorides-18 month results. J Dent, 44, 57-63.
Fegert, J. M., Vitiello, B., Plener, P. L., & Clemens, V (2020). Challenges and burden of the Coronavirus 2019 (COVID-19) pandemic for child and adolescent mental health: a narrative review to highlight clinical and research needs in the acute phase and the long return to normality. Child Adolesc Psychiatry Ment Health, 14, 20.
Fung, M. H. T., Duangthip, D., Wong, M. C. M., Lo, E. C. M., & Chu, C. H. (2016). Arresting Dentine Caries with Different Concentration and Periodicity of Silver Diamine Fluoride. JDR Clin Trans Res, 1(2), 143-52.
Fung, M. H. T., Duangthip, D., Wong, M. C. M., Lo, E. C. M., & Chu, C. H. (2018). Randomized Clinical Trial of 12% and 38% Silver Diamine Fluoride Treatment. J Dent Res, 97(2), 171-8.
Gao, S. S., Zhao, I. S., Hiraishi, N., Duangthip, D., Mei, M. L., Lo, E. C. M., & Chu, C. H. (2016). Clinical trials of silver diamine fluoride in arresting caries among children: a systematic review. JDR Clin Transl Res, 1(3), 201-10.
Garrett L (2020). COVID-19: the medium is the message. Lancet, 395(10228), 942-943.
Horst, J. A., Ellenikiotis, H., & Milgrom, P. L (2016). UCSF Protocol for Caries Arrest Using Silver Diamine Fluoride: Rationale, Indications and Consent. J Calif Dent Assoc. 44(1), 16-28.
Johhnson, B., Serban, N., Griffin, P. M., & Tomar, S L. (2019). Projecting the economic impact of silver diamine fluoride on caries treatment expenditures and outcomes in young U.S. children. J Public Health Dent. 79(3), 215-21.
Kissler, S. M., Tedijanto, C., Goldstein, E., Grad, Y. H., & Lipsitch, M (2020). Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period. Science, 368(6493), 860-8.
Klein, U., Kanellis, M & Drake, D (1999). Effects of four anticaries agents on lesion depth progression in an in vitro caries model. Pediatr Dent, 21(3), 176-180.
Knight, G. M., McIntyre, J. M., Craig, G. G., Mulyani Zilm, O. S., & Gully, N. J. (2005). An in vitro model to measure the effect of a silver fluoride and potassium iodide treatment on the permeability of demineralized dentine to Streptococcus mutans. Aust Dent J, 50(4), 242-245.
Kumar, S., Tadakamadla, J., Duraiswamy, P., & Kulkarni, S (2016). Dental Caries and its Socio-Behavioral Predictors- An Exploratory Cross-Sectional Study. J Clin Pediatr Dent, 40(3), 186-192.
Llodra, J. C., Rodriguez, A., Ferrer, B., Menardia, V., Ramos, T., & Morato, M (2005). Efficacy of silver diamine fluoride for caries reduction in primary teeth and first permanente molars of schoolchildren: 36-month clinical trial. J Dent Res. 84(8), 721-724.
Luzzi, V., Ierardo, G., Bossù, M., & Polimeni, A (2020). COVID-19: Pediatric Oral Health during and after the Pandemics. Appl. Sci., 10, x.
Matrajt, L & Leung, T (2020). Evaluating the Effectiveness of Social Distancing Interventions to Delay or Flatten the Epidemic Curve of Coronavirus Disease. Emerg Infect Dis, 26(8), 10.
Mazzoni, A., Tjäderhane, L., Checchi, V., Di Lenarda, R., Salo, T., Tay, F. R., Pashley, D. H., et al (2015). Role of dentin MMPs in caries progression and bond stability. J Dent Res, 94(2), 241-251.
Mei, M. L., Li, Q. L., Chu, C H., Yiu, C K., & Lo, E C. (2012). The inhibitory effects of silver diamine fluoride at different concentrations on matrix metalloproteinases. Dent Mater, 28(8), 903-8.
Mei, M. L., Li, Q. L., Chu, C H., Lo, E. C., & Samaranayake, L. P (2013). Antibacterial effects of silver diamine fluoride on multi-species cariogenic biofilm on caries. Ann Clin Microbiol Antimicrob, 12,4.
Mei, M. L., Ito, L., Cao, Y., Li, QL., Chu, C. H., & Lo, E. C (2014). The inhibitory effects of silver diamine fluorides on cysteine cathepsins. J Dent, 42(3), 329-335.
Mei, M. L., Lo, E. C. M., & Chu, C. H. (2016). Clinical use of silver diamine fluoride in dental treatment. Compend Contin Educ Dent, 37(2), 93-8.
Meng, L., Hua, F & Bian, Z (2020). Coronavirus Disease 2019 (COVID-19): Emerging and future challenges for dental and oral medicine. J Dent Res, 99, 481-7.
Milgrom, P., Horst, J. A., Ludwig, S., Rothen, M., Chaffee B. W., et al (2017). Topical Silver Diamine Fluoride for Dental Caries Arrest in Preschool Children: A Randomized Controlled Trial and Microbiological Analysis of Caries Associated Microbes and Resistance Gene Expression. J Dent, S0300-5712(17), 30212-30219.
Obermajer, N., Jevnikar, Z., Doljak, B., & Kos, J (2008). Role of cysteine cathepsins in matrix degradation and cell signalling. Connect Tissue Res, 49(3), 193-196.
Oliveira, B. H., Rajendra, A., Veitz-Keenan, A., & Niederman, R (2019). The effect of silver diamine fluoride in preventing caries in the primary dentition: a systematic review and meta-analysis. Caries Res, 53(1), 24-32.
Organização Mundial da Saúde (OMS) (2020). Overview of public health and social measures in the context of COVID-19. Interim guidance. https://www.who.int/publications/i/item/overview-of-public-health-and-social-measures-in-the-context-of-covid-19.
Organização Mundial da Saúde (OMS) (2017). WHO Expert Consultation on Public Health Intervention against Early Childhood Caries: report of a meeting, Bangkok, Thailand. World Health Organization.
Pitts, N., Baez, R., Diaz-Guallory, C., et al. (2019). Early Childhood Caries: IAPD Bangkok Declaration. Int J Paediatr Dent, 29:384-386
Rosas, S. G. P., Tellez, M. A. A., & EspinozaII, E. V. (2014). In vitro efficiency of fluoride-containing compounds on remineralization of carious enamel lesions under cyclic pH conditions. Revista Odontológica Mexicana,18(2), 96-104.
Rosenblatt, A., Stamford, T. C., & Niederman R (2009). Silver diamine fluoride: a caries "silver-fluoride bullet". J Dent Res, 88(2),116-25.
Schwendicke, F., Splieth, C., Breschi, L., et al (2019). When to intervene in the caries process? An expert Delphi consensus statement. Clin Oral Investig, 23(10), 3691-703.
Soares-Yoshikawa, A. L., Cury, J. A., & Tabchoury, C. O. M. (2020). Fluoride Concentration in SDF Commercial Products and Their Bioavailability with Demineralized Dentine. Braz Dent J, 31(3), 257-263.
Suzuk,i T., Tsutsum, N., Sobue, S et al (1976). Effect of diammine silver fluoride on plaque formation by Streptococcus mutans 2. Mode of action of plaque inhibition. Jpn J Oral Biol, 18, 268-278.
Suzuki, T., Nishida, M., Sobue, S., & Moriwaki, Y (1974). Effects of diammine silver fluoride on tooth enamel. J Osaka Univ Dent Sch, 14, 61-72.
Tinanoff, N., Baez, R. J., Diaz Guillory, C., Donly, K. J., Feldens, C. A., McGrath, C., Phantumvanit, P., Pitts, N. B., Seow, W. K., Sharkov, N., Songpaisan, Y., & Twetman, S (2019). Early childhood caries epidemiology, aetiology, risk assessment, societal burden, management, education, and policy: Global perspective. Int J Paediatr Dent, 29(3), 238-48.
Yee, R., Holmgren, C., Mulder, J., Lama, D., Walker, D., & van Palenstein Helderman, W (2009). Efficacy of silver diamine fluoride for Arresting Caries Treatment. J Dent Res, 88(7), 644-7.
Zhao, I. S., Gao, S. S., Hiraishi, N., Burrow, M. F., Duangthip, D., Mei, M. L., et al (2018). Mechanisms of silver diamine fluoride on arresting caries: a literature review. Int Dent J, 68(2), 67-76.
Zhi, Q. H., Lo, E. C., & Lin, H. C (2012). Randomized clinical trial on effectiveness of silver diamine fluoride and glass ionomer in arresting dentine caries in preschool children. J Dent, 40(11), 962-7.
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