Systematic review of the effect of endodontic irrigants over coronaviruses




Coronavirus; Sodium hypochlorite; Covid-19; SARS-CoV-2.


Objective: This systematic review aimed to discuss a possible effect of sodium hypochlorite (NaOCl) over the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the new generation of corona virus, which was reported firstly in December 2019 in Wuhan, China. Methods: Electronic search was performed for studies up to March 31, 2021 in the following databases: PubMed, LILACS, BBO, Scopus, web of science and Cochrane considering clinical trials and laboratory studies that evaluated the action of NaOCl over SARS-CoV-2. Results: Numerous founded studies reported effectivity of NaOCl in different concentrations and exposure times over corona viruses including the SARS-CoV-2. However, none of the studies evaluated this action in the root canal system. No metanalysis was conducted due to variability of methods or lack of information of included articles. Conclusion: NaOCl has a possible effectivity over SARS-CoV-2 as it dissolves the organic material of virus membrane, but this should be evaluated in the root canal systems.


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How to Cite

HASNA, A. A. .; BRESCIANI, E. . Systematic review of the effect of endodontic irrigants over coronaviruses. Research, Society and Development, [S. l.], v. 10, n. 6, p. e23810615457, 2021. DOI: 10.33448/rsd-v10i6.15457. Disponível em: Acesso em: 20 jul. 2024.



Review Article