Monoetanolamine oleate 5% as a treatment for childhood hemangioma: An experience report
DOI:
https://doi.org/10.33448/rsd-v10i6.15568Keywords:
Sclerotherapy; Hemangioma; Therapy.Abstract
Vascular anomalies in the head and neck represent a complex group of lesions of congenital or acquired origin, with childhood hemangioma (HI) as the most common benign vascular tumor in childhood. HI is characterized by a phase of rapid growth followed by an involuted phase, usually present before the first year of life. Sclerotherapy is one of the standard treatments for this type of anomaly, even though there is still no standardized protocol for this purpose. Thus, considering the efficacy and safety data of sclerotherapy with monoethanolamine oleate (OM) reported in the literature, the aim of this study is to report the use of 5% OM in patients with HI. This is a descriptive study, with a qualitative approach, of the experience report type, with intralesional injections of approximately 0.1 ml of 5% OM for 4 mm of lesion with an interval of 14 days between sessions. As a result, complete resolution of all four cases was obtained with two sessions of intralesional injection of OM of 5%. Sclerotherapy with OM is an affordable and acceptable treatment option that has proven effective when used properly, but it is extremely important to carry out an individual and personalized treatment for each case.
References
Baer, A. H., Parmar, H. A., Dipietro, M. A., Kasten, S. J., & Mukherji, S. K. (2011). Hemangiomas and vascular malformations of the head and neck: A simplified approach. Neuroimaging Clin N Am, 21, 641-58.
Ballah, D., Cahill, A. M., Fontalvo, L., Yan, A., Treat, J., Low, D. & Epelman M.(2011). Vascular anomalies: what they are, how to diagnose them, and how to treat them. Curr Probl Diagn Radiol., 6 (40), 233-247. 10.1067 / j.cpradiol.2011.04.001.
Bonan, P. R. F., Miranda, L. P., Mendes, D. C., de Paula, A. M. B., Pego, S. P. B., & Júnior, H. M. (2007). Efferctives of low flow vascular lesions sclerosis with monoethanolamine: Report of six cases. Med Oral Patol Oral Cir Bucal., 12, 524-527. http://www.medicinaoral.com/pubmed/medoralv1 2_i7_pE524.pdf.
Brahmbhatt, A. N., Skalski, K. A., & Bhatt, A. A. (2020). Vascular lesions of the head and neck: an update on classifcation and imaging review. Insights Imaging., 11, 19.10.1186 / s13244-019-0818-3.
Bruckner, A. L., & Frieden, I. J. (2003) Hemangiomas of infancy. J Am Acad Dermatol, 48(3), 477-493. 10.1067 / mjd.2003.200.
Corrêa, P. H., Nunes, L. C., Johann, A. C. B. R., Aguiar, M. C. F., Gomez, R. S, & Mesquita, R. A. (2007) Prevalence of oral hemangioma, vascular malformation and varix in a Brazilian population. Braz Oral Res, 21 (1), 40-45. 10.1590 / s1806-83242007000100007.
Costa, J. R. S., Torriani, M. A., Hosni, E. S., D'Avila, O. P., & Figueiredo, P. J. (2011). Sclerotherapy for vascular malformations in the oral and maxillofacial region: treatment and follow-up of 66 lesions. J Oral Maxillofac Surg, 69, 88-92. 10.1016 / j.joms.2010.06.204.
Da Silva, W. B., Ribeiro, A. L., de Menezes, S. A. F., Pinheiro, J. J. V., & Junior, S. M. A. (2014). Oral capillary hemangioma: a clinical protocol of diagnosis and treatment in adults. Oral Maxillofac Surg., 18 (4), 431-437. 10.1007 / s10006-013-0436-z.
Eivazi, B., & Werner, J. A. (2013). Management of vascular malformations and hemangiomas of the head and neck - an update. Curr Opin Otolaryngol Head Neck Surg, 21, 157-163. 10.1097 / MOO.0b013e32835e15a9.
Enjoras, O., Wassef, M., & Chapot, R. (2013). Introduction: ISSVA classification. Cambridge University Press. http://assets.cambridge.org/97805218/ 48510/exce rpt/9780521848510_excerpt.pdf.
Fernandes, D. T., Elias, R. A., Santos-Silva, A. R., Vargas, P. A., & Lopes, M. A. (2018). Benign oral vascular lesions treated by sclerotherapy with ethanolamine oleate: A retrospective study of 43 patients. Med Oral Patol Oral Cir Bucal, 23 (2), 180-e187. 10,4317 / medoral.22253.
GREENE, A. K. (2012). Current concepts of vascular anomalies. J Craniofac Surg, 23, 220-224. https://journals.lww.com/jcraniofacialsurgery/Abs tract/2012/0100 0/Current_Concepts_of_Vascular_Anomalies.54.aspx
Haggstrom, A. N., Drolet, B. A., Baselga, E., Chamlin, S. L., Garzon, M. C., Horii, K. A., Lucky, A. W., Mancini, A. J. , Metry, D. W., Newell, B. , Nopper, A. J., & Frieden, I. J. (2007) Prospective study of infantile hemangiomas: demographic, prenatal, and perinatal characteristics. J Pediatr, 150, 291–294. 10.1016 / j.jpeds.2006.12.003.
Kaji, N., Kurita, M., Ozaki, M., Takushima, A., Harii, K., Narushima, M., & Wakita, S (2009). Experience of sclerotherapy and embolosclerotherapy using ethanolamine oleate for vascular malformations of the head and neck. Cand J Plast Reconstr Surg Hand Surg, 43, 126-136.
Kato, C.N.A.O., Ribeiro, M. C., do Amaral, M. B. F, Grossmann, S. M. C, de Aguiar, M. C. F., & Mesquita, R. A. (2019) Experience with 5% ethanolamine oleate for sclerotherapy of oral vascular anomalies: A cohort of 15 consecutive patients. J Craniomaxillofac Surg., 47 (1), 106-111. 10.1016 / j.jcms.2018.11.009.
ISSVA classification for vascular anomalies © (2018) http://issva.org/classification.
Johann, A. C. B. R., Aguiar, M. C. F., do Carmo, M. A. V , Gomez, R. S. , Castro, W. H., & Mesquita, R. A.. (2005) Sclerotherapy of benign oral vascular lesion with ethanolamine oleate: An open clinical trial with 30 lesions. Oral Surg Oral Med Oral Pathol Oral Radiol Endod., 100 (5), 579-584. 10.1016 / j.jcms.2018.11.009.
Mariano, F.V., Vargas, P.A. , Coletta, R. D., & Lopes, M. A. (2011). Sclerotherapy followed by surgery for the treatment of oral hemangioma: a report of two cases. Gen Dent., 59 (3), 121-125.
Nair, S.C. (2018). Vascular anomalies oh the head and neck region. J Maxillofac Oral Surg, 17 (1), 1-12.
Ozaki, M., Kurita, M., Kaji, N., Fujino, T., Narushima, M., Takushima, A., & Harii, K. (2010) Efficacy and evaluation of safety of sclerosants for intramuscular venous malformations: clinical and experimental studies. Scand J Plast Reconstr Surg Hand Surg, 44, 75-87. 10.3109 / 02844310903569725.
Pereira, A. S., Shitsuka, D. M., Parreira F. J., & Shitsuka, R. (2018). Metodologia da pesquisa científica. UFSM.
Sadick, M., Wohlgemuth, W. A., Huelse, R., Lange, B., Henzler, T., Schoenberg, S. O., & Sadick, H. (2017) Interdisciplinary management of head and neck vascular anomalies: clinical presentation, diagnostic findings and minimal invasive therapies. Eur J Radiol Open, 14, 63-68. 10.1016 / j.ejro.2017.05.001.
Sigaux, N., Viremouneix, L., Guibaud, L., & Bretão, P. (2015). Head and neck superficial venous malformations. Rev Stomatol Chir Maxillofac Chir Orale, 116, 201-208.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2021 Anne Diollina Araújo Morais; Carlos Eduardo Nogueira Nunes; Irla Maria Sousa Moura; Filipe Nobre Chaves; Marcelo Bonifácio da Sila Sampieri; Denise Hélen Imaculada Pereira de Oliveira
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.