Fournier's gangrene: New therapeutic approaches with the use of negative pressure and hyperbaric oxygen therapy

Authors

DOI:

https://doi.org/10.33448/rsd-v10i7.16686

Keywords:

Fournier Gangrene; Fasciitis Necrotizing; Negative-Pressure Wound Therapy; Hyperbaric oxygenation.

Abstract

Objective: To review the available scientific literature, in order to synthesize some forms of adjuvant treatment available in the management of patients with FG. Methods: research on some indexing platforms, a total of 17 articles, published in the last 7 years, which related to adjuvant methods to the treatment of Fournier's Gangrene, in particular hyperbaric oxygen therapy and wound treatment therapy with the use, were selected of negative pressure. Results and Discussion: The methods used as adjuvants for wound closure contribute positively to the recovery of patients with FG, when reported after indication. The wound closure therapy assisted in the reduction, if useful in controlling the environment of recovery from the injury and reducing the time of clinical treatment without interfering in the mortality of the disease. Hyperbaric oxygen therapy has a direct antibacterial effect on anaerobics, improves the phagocytic action of neutrophils, increases angiogenesis and reduces edema. Negative pressure therapy is used in the acute and repair phases, accelerating the appearance of granulation tissue. Conclusion: The use of adjuvant methods to the treatment of Fournier's Gangrene is promising and, with exceptions, demonstrate better wound recovery when compared to patients who do not use them, and after professional and individualized clinical evaluation of the cases, such methods can be allies in the recovery of the sick.

References

Agostini T., Mori, F., Perello, R., Dini, M., & Russo, G. (2014). Successful combined approach to a severe Fournier's gangrene. Indian J Plast Surg. 47(01), 132-136.

Azevedo, C. C. S. F., Araújo, A. P. L. de, Marin, C. V., Baldi, D., & Alves, J. P. F. (2016). Síndrome de Fournier: um artigo de revisão. Revista Eletrônica do UNIVAG, (15), 70-78.

Boughanmi, F., Ennaceur, F., Korbi, I., Chaka, A., Noomen, F., & Zouari, K. (2021). Fournier’s gangrene: its management remains a challenge. Pan Afr Med J, 38(23).

Caldas, N. G., Fernandes, S. S., Aguiar, E. J. de, Silva, A. A. M., & Medrei, N. R. (2019). O uso da terapia a vácuo no tratamento da síndrome de fournier - revisão da literatura, experiência do serviço e série de casos. Relatos Casos Cir, 5(3), e2229.

Chernyadyev, S. A., Ufimtseva, M. A., Vishnevskaya, I. F., Bochkarev, Y. M., Ushakov, A. A., Beresneva, T. A., Galimzyanov, F. V., & Khodakov, V. V. (2018). Fournier’s Gangrene: Literature Review and Clinical Cases. Urol Int, 101(1), 91–97.

Cruz, R. A. O., Andrade, L. L. de, & Arruda, A. J. C. G. de. (2016). Produção científica sobre Gangrena de Fournier e os cuidados de enfermagem: revisão integrativa. Rev enferm UFPE on line, 10(5), 4329-35.

Féres, O., Ribeiro, M., Joaquim, J., Rocha, R., Miranda, J., Santos, L., Féres, A., Camargo, H., & Parra, R. (2021). Hyperbaric oxygen therapy decreases mortality due to Fournier’s gangrene: a retrospective comparative study. Medical Gas Research. 11(1), 18-23.

Ferretti, M., Saji, A., & Phillips, J. (2017). Fournier's Gangrene: A Review and Outcome Comparison from 2009 to 2016. Advances In Wound Care. 6 (9), 289-295.

Galvão, T. F., Pansan, T., & Harrad, D. (2015). Principais itens para relatar Revisões sistemáticas e Meta-análises: A recomendação PRISMA. Epidemiol. Serv. Saúde. 24 (2)

Iacovelli, V., Cipriani, C., Sandri, M., Filippone, R., Ferracci, A., Micali, S., Rocco, B., Puliatti, S., Ferrarese, P., Benedetto, G., Minervini, A., Cocci., A., Luigi Pastore, A., Salhi,Y., Antonelli, A., Morena, T., Volpe, A., Poletti, P., Celia, A., Zeccolini G., Leonardo, C., Proietti, F., Finazzi., E & Bove, P. (2021). The role of vacuum-assisted closure (VAC) therapy in the management of FOURNIER’S gangrene: a retrospective multi-institutional cohort study. World Journal of Urology, 39(1), 121-128.

Inácio, M. F., Lima, R. P., Rizzo Neto, S., Lopes, F. A., Pantaroto, M., & Sousa, A. V. de. (2020). Epidemiological study on Fournier syndrome in a tertiary hospital in Jundiaí-SP from October 2016 to October 2018. J Coloproctol, 40(1), 37–42.

Ioannidis, O., Kitsikosta, L., Tatsis, D., Skandalos, I., Cheva, A., Gkioti, A., Varnalidis, I., Symeonidis, S., Savvala, N. A., Parpoudi, S., Paraskevas, G. K., Pramateftakis, M. G., Kotidis, E., Mantzoros, I., & Tsalis, K. G. (2017). Fournier’s gangrene: lessons learned from Multimodal and Multidisciplinary Management of Perineal necrotizing Fasciitis. Perineal. Front. Surg. 4:36.

Kuchinka, J., Matykiewicz, J., Wawrzycka, I., Kot, M., Karcz, W., & Głuszek, S. (2019) Fournier gangrene – a challenge for the surgeon. Pol Przegl Chir. 92 (5), 1-5.

Larsson, J.C., Pires, R., Fioravanti, A., Beolchi, M.P., Gradel, J., & Oliveira, M (2017). Abordaje quirúrgico combinado como alternativa mínimamente invasiva en el tratamiento de la Gangrena de Fournier. Cirurgia Plástica Ibero-Latinoamericana. 43(1), 87-96.

Lee, J., Jung, H., Kwon, H., & Jung, S. (2014). Extended negative pressure wound therapy-assisted dermatotraction for the closure of large open fasciotomy wounds in necrotizing fasciitis patients. World J Emerg Surg. 9(29).

Lima, F. L. O., Almeida, F. C. de, Góes, F. S. R., & Izabel, T. S. S. (2019). Síndrome de Fournier e sua potencial variabilidade microbiológica. Visão Acadêmica, 20(3).

Moreira, D. R., Gonçalves, A. L. S., Aucelio, R. S., & Silva, K. G. da. (2017). Terapêutica cirúrgica na síndrome de Fournier: relato de caso. Rev Med, 96(2), 116-20.

Ritter, O. M. S., Allonço, M., & Lima, F. (2021). Content analysis as a methodology in Qualis-CAPES A1 journals in Science Education. Research, Society and Development. Research Society and Development. 10(3), p. e43110313378

Rodríguez, A. M. V., Larios, C. A. G., García, G. A. C., Rodríguez, I. V. S., & López, J. L. P. (2015). Gangrena de Fournier. Rev.Medica.Sanitas, 18(4), 212-219.

Schneidewind, L., Anheuser, P., Schönburg, S., Wagenlehner, F., & Kranz, J. (2021). Hyperbaric Oxygenation in the Treatment of Fournier's Gangrene: A Systematic Review. Urologia Internationalis. 105(3-4), 247–256.

Singh, A., Ahmed, K., Aydin, A., Khan, M. S., & Dasgupta, P. (2016). Fournier’s gangrene. A clinical review. Arch Ital Urol Androl, 88(3), 157-164.

Syllaios, A., Davakis,S., karydakis, I., Vailas, M., Garmpis, N., Mpaili, E., kyros, E., Felekouras, E., & Papalampros, A. (2020). Treatment of Fournier's Gangrene With Vacuum-assisted Closure Therapy as Enhanced Recovery Treatment Modality. In Vivo. 34 (3), 1499-1502.

Vaz, A. C. R., Vale, M. L. F. do, & Vale, M. F do. (2006). Relato de caso: Gangrena de Fournier. Unimontes Científica, 8(1), 129-134.

Yanaral, F., Balci, C., Ozgor, F., Simsek, A., Onuk, O., Aydin, M., & Nuhoglu, B. (2017). Comparison of conventional dressings and vacuum-assisted closure in the wound therapy of Fournier's gangrene. Arch Ital Urol Androl, 89(3), 208-211.

Ye, J., Xie, T., Wu, M., Ni, P., & Lu, S. (2015). Negative Pressure Wound Therapy Applied Before and After Split-Thickness Skin Graft Helps Healing of Fournier Gangrene A Case Report (CARE-Compliant). Medicine. 94(5), e426.

Yücel M., Özpek A., Başak F., Kılıç A., Ünal E., Yüksekdağ S., & Acar A., Baş G. (2017). Fournier's gangrene: A retrospective analysis of 25 patients. Ulus Travma Acil Cerrahi Derg. 23(5), 400-404.

Zhang, N., Yu, X., Zhang, K., & Liu, T. (2020). A retrospective case series of Fournier’s gangrene: necrotizing fasciitis in perineum and perianal region. BMC Surg. 20(259).

Published

29/06/2021

How to Cite

FERREIRA, F. A. .; SANTOS, T. B. dos; SOUZA, V. H. S. de; LOPES, N. C. G. .; LEITE, C. Q. .; BRAGA, L. Q. .; ROCHA, F. S. P. .; RAMALHO, V. G. .; SOUZA, G. A. R. de .; SANTOS, B. F. dos . Fournier’s gangrene: New therapeutic approaches with the use of negative pressure and hyperbaric oxygen therapy . Research, Society and Development, [S. l.], v. 10, n. 7, p. e46410716686, 2021. DOI: 10.33448/rsd-v10i7.16686. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/16686. Acesso em: 25 apr. 2024.

Issue

Section

Health Sciences