Blocking tubules technologies for dentin hypersensitivity in periodontal patients – pilot study




Dentin hypersensitivity; dentin hypersensitivity, root exposure, periodontal disease, periodontal treatment, desensitizing agents; Periodontal disease; Desensitizing agents.


Periodontal patients often report dentin hypersensitivity (DH) caused by root surface exposure or periodontal treatment. Tubular blocking technologies in toothpastes are effective for pain relief, but no specific chemical/physical agent has been reported for periodontal patients. This double-blind randomized clinical trial compared the effects of three technologies in reducing DH in periodontal patients. Eighteen (18) participants were randomly assigned into three groups: SEN (NOVAMIN technology); REG (REFIX technology); REGK (REFIX technology + potassium citrate). Periodontal patients presenting with DH were evaluated at 6 moments: T1 and T2 - immediately before and after scaling and root planing procedures (SRP); T3 - after polishing sensitive areas with their assigned dentifrice and T4, T5, T6 - after 2, 4 and 8 weeks of SRP respectively. Sensitivity was assessed by air blast (Schiff scale) and patients’ perceptions using the visual analogue scale (VAS). Data were analyzed by two-way repeated measures ANOVA complemented by the Tukey test with significance set at 5% (p <0.05). Preliminary outcomes revealed SEN, REG and REGP reduced DH in periodontal patients (n=18). All patients initially presented moderate to severe pain (64.3) and after treatment they reported mild pain (21.3). Similarly, the dentist evaluation showed significant reduction in DH with the use of the three technologies (2.26 to 0.56). No statistically significant differences were found between the three study groups for patients (p=0.751) and dentist evaluations (p=0.632). According to these preliminary outcomes, all three technologies equally reduced DH in periodontal patients. Clinical trials #NCT04422184


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How to Cite

ZANGRANDO, M. S. R. .; SILVA, G. F. F. .; BIGOTTO, M. L. B. .; CINTRA, F. M. R. N. .; DAMANTE, C. A. .; SANT’ANA, A. C. P. .; VILHENA, F. V. . Blocking tubules technologies for dentin hypersensitivity in periodontal patients – pilot study. Research, Society and Development, [S. l.], v. 10, n. 13, p. e35101320398, 2021. DOI: 10.33448/rsd-v10i13.20398. Disponível em: Acesso em: 3 dec. 2021.



Health Sciences