Albuminúria and factors associated with chronic kidney disease in obesity
DOI:
https://doi.org/10.33448/rsd-v10i12.20490Keywords:
Proteinuria; Albuminuria ; Chronic Renal Insufficiency; Risk factors; Bariatric Surgery; Morbid obesity.Abstract
Introduction: Albuminuria is an important marker for increased morbidity and mortality in obese and a screening parameter for early renal changes. However, few studies associate the impact of obesity on albuminuria. Objective: To relate albuminuria and risk factors for chronic kidney disease with obesity. Methods: Cross-sectional study with obese patients, over 18 years old, without a diagnosis of chronic kidney disease, allocated according to the Body Mass Index, in groups A (30-39,99 kg/m² and 40-49 kg/m²) and B (≥50 kg/m² and ≥60 kg/m²). Renal evaluation occurs through the measurement of albuminuria, urea and creatinine. Lipid, inflammatory and glycemic profile were also evaluated. Chi-square, student t, Mann-Whitney and Spearman correlation tests were performed, with the Statistical Package for the Social Sciences software. The results were achieved with a significance level of p <0,05 and a 95% confidence interval. Results: 97 obese individuals had an albuminuria frequency of 21.6%, with no statistical difference between the groups. The decreased serum levels of HDL and increased CRP when related to the additional body mass index p <0,05. Of the risk factors, it was observed that the obese> 40 years old had a higher prevalence of hypertension. Albuminuria has a low correlation with age and body mass index (0,031 and 0,136, respectively). Conclusion: The frequency of albuminuria was high, but it was not associated with the severity of obesity. Obese middle-aged adults have more risk factors for kidney damage.
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