Mucolytic action of bromelain: an integrative review

Authors

DOI:

https://doi.org/10.33448/rsd-v10i13.21495

Keywords:

Bromelains; Mucus; Bodily Secretions.; Bromelains; Mucus; Bodily secretions.

Abstract

Bromelain has anti-inflammatory, antioxidant, anti-cancer properties and also works as an aid in the digestion process and as a cardioprotective agent. The aim of the study was to analyze through the scientific literature the mucolytic action of bromelain. This is a literature review of the literature, which was used to generate the guiding question: “What scientific evidence shows the mucolytic action of bromelain?”. Seven studies included in this review, all with a quantitative approach to data (100%); concentrated mainly in the year 2017 (42.9%) and all were in the English language (100%), with origin of studies published in Austria (42.9%), the European Journal of Pharmaceutics and Biopharmaceutics concentrated more publications, corresponding to 28.6%. The studies addressed the use of bromelain associated with other substances, the effects of bromelain, such as improving permeability for drugs, and its action on the intestinal mucus, making it more permeable. The study allowed for the expansion of knowledge about bromelain or bromelain as a mucolytic agent, its nutraceutical potentials and action against some pathologies, in addition to its possible use by the pharmaceutical industry for the creation of drugs that overcome the mucolytic barrier more easily.

Author Biographies

Eduardo Henrique Barros Ferreira, Universidade de San Lorenzo

Universidade de San Lorenzo

Chrisllayne Oliveira da Silva, Universidade Federal do Maranhão

Universidade Federal do Maranhão

Jesineide Sousa da Silva , Centro Universitário de Ciências e Tecnologia do Maranhão

Centro Universitário de Ciências e Tecnologia do Maranhão

Laila da Silva Mota Vilanova, Centro Universitário de Ciências e Tecnologia do Maranhão

Centro Universitário de Ciências e Tecnologia do Maranhão

Francisléia Falcão França Santos Siqueira , Universidade Estadual do Maranhão

Universidade Estadual do Maranhão

Solygardia Albuquerque Maciel Teixeira , Centro Universitário Nossa Senhora do Patrocino

Centro Universitário Nossa Senhora do Patrocino

Hálmisson D’Árley Santos Siqueira, Centro Universitário de Ciências e Tecnologia do Maranhão

Centro Universitário de Ciências e Tecnologia do Maranhão

Raimundo Nonato Cardoso Miranda Junior, Centro Universitário de Ciências e Tecnologia do Maranhão

Centro Universitário de Ciências e Tecnologia do Maranhão

Hádila Giovanna Santos Siqueira Cunha, Universidade Federal do Maranhão

Universidade Federal do Maranhão

Jairina Nunes Chaves, Universidade Estadual do Maranhão

Universidade Estadual do Maranhão

Rodolfo Ritchelle Lima dos Santos, Universidade Federal do Piauí

Universidade Federal do Piauí

Camilla Lohanny Azevedo Viana, Centro Universitário de Ciências e Tecnologia do Maranhão

Centro Universitário de Ciências e Tecnologia do Maranhão

Marconny Lira da Silva, Centro Tecnológico de Ensino Múltiplo

Centro Tecnológico de Ensino Múltiplo

Ney Rômulo de Oliveira Paula, Universidade Federal do Piauí

Universidade Federal do Piauí

References

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Published

21/10/2021

How to Cite

FERREIRA, E. H. B. .; MELO, K. C. .; SILVA, C. O. da .; SILVA , J. S. da .; VILANOVA, L. da S. M. .; SIQUEIRA , F. F. F. S. .; TEIXEIRA , S. A. M. .; SIQUEIRA, H. D. S. .; MIRANDA JUNIOR, R. N. C.; CUNHA, H. G. S. S.; CHAVES, J. N. .; SANTOS, R. R. L. dos .; VIANA, C. L. A.; SILVA, M. L. da .; PAULA, N. R. de O. . Mucolytic action of bromelain: an integrative review . Research, Society and Development, [S. l.], v. 10, n. 13, p. e557101321495, 2021. DOI: 10.33448/rsd-v10i13.21495. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/21495. Acesso em: 8 dec. 2021.

Issue

Section

Review Article