Analysis of the interventions used in the prevention and control of postpartum hemorrhage: an integrative literature review
DOI:
https://doi.org/10.33448/rsd-v10i16.22836Keywords:
Postpartum hemorrhage; Prevention and control; Effectiveness of interventions; Obstetric nursing.Abstract
Postpartum hemorrhage (PPH) is defined as a blood loss ≥ 500 mL that occurs within 24 hours after delivery, when this loss is greater than 1,000 mL it is considered severe. PPH is among the leading causes of severe maternal morbidities, accounting for about 25% of all deaths of pregnant women worldwide, especially in low-income countries. In Brazil, it is the second leading cause of maternal death. This study aimed to analyze the scientific production on interventions used to prevent and control postpartum hemorrhage. This was a bibliographic research of the integrative literature review type; studies were extracted from the PubMed (National Library of Medicine), BVS (Virtual Health Library) and CINAHL (Cumulative Index to Nursing and Allied Health Literature) databases. We used 14 studies published from 2016 to 2021. The predominant level of evidence was II - randomized clinical trial, 11 studies obtained grade recommendation A. The results conclude that the interventions analyzed as effective for the prevention of postpartum hemorrhage were: oxytocin, misoprostol, carbetocin, ergometrine or methylergometrine, active management in the third period of labor and uterine artery ligation. In the control of PPH were: tranexamic acid, uterine balloon tamponade (BTU) and the non pneumatic anti-shock suit (NASG).
References
Adnan, N., Conlan-Trant, R., Mccormick, C., Boland, F., & Murphy, D. J. (2018). Intramuscular versus intravenous oxytocin to prevent postpartum haemorrhage at vaginal delivery: randomised controlled trial. Bmj, 362, 3546.
Amornpetchakul, P., Lertbunnaphong, T., Boriboonhiransarn, D., Leetheeragul, J., Sirisomboon, R., & Jiraprasertwong, R. (2018). Intravenous carbetocin versus intravenous oxytocin for preventing atonic postpartum hemorrhage after normal vaginal delivery in high-risk singleton pregnancies: a triple-blind randomized controlled trial. Archives Of Gynecology And Obstetrics, 298(2), 319-327.
Anger, H., Dabash, R., Durocher, J., Hassanein, N., Ononge, S., Frye, L., . . . & Darwish, E. (2019). The effectiveness and safety of introducing condom‐catheter uterine balloon tamponade for postpartum haemorrhage at secondary level hospitals in Uganda, Egypt and Senegal: a stepped wedge, cluster⠰randomised trial. Bjog: An International Journal of Obstetrics & Gynaecology, 12613, 1612-1621.
Asmat, R., Ashraf, T., Asmat, S., Asmat, N., & Asmat, F. (2017). Effectiveness of Per Rectal Misoprostol Versus Intramuscular Oxytocin for Prevention of Primary Postpartum Haemorrhage. Journal Of The College Of Physicians And Surgeons, 27(1), 13-17.
Aziz, M. A. A. E., Iraqi, A., Abedi, P., & Jahanfar, S. (2018). The effect of carbetocin compared to misoprostol in management of the third stage of labor and prevention of postpartum hemorrhage: a systematic review. Systematic Reviews, 7(1), 170-177.
Begley, C. M., Devane, D., Murphy, D. J., Gyte, G. M., Mcdonald, S. J., & Mcguire, W. (2019). Active versus expectant management for women in the third stage of labour. Cochrane Database Of Systematic Reviews, 1-142.
Bi, S., Zhang, L., Chen, J., Huang, M., Huang, L., Zeng, S., . . . & Wen, Suiwen. (2021). Maternal age at first cesarean delivery related to adverse pregnancy outcomes in a second cesarean delivery: a multicenter, historical, cross-sectional cohort study. Bmc Pregnancy And Childbirth, 21, 1-10.
Bienstock, J. L., Eke, A. C., Hueppchen, N. A. (2021). Postpartum Hemorrhage. New England Journal Of Medicine, 384(17), 1635-1645.
Bork, A.M.T. (2005). Enfermagem baseada em evidencias. Rio de Janeiro: Guanabara Koonga.
Carvalho, N., Hoque, M. E., Oliver, V. L., Byrne, A., Kermode, M., Lambert, P., . . . & Morgan, A. (2020). Cost-effectiveness of inhaled oxytocin for prevention of postpartum haemorrhage: a modelling study applied to two high burden settings. Bmc Medicine, 18(1), 8-18.
Darwish, A. M., Abdallah, M. M., Shaaban, O. M., Ali, M. K., Khalaf, M., & Sabra, A. M. A. (2017). Bakri balloon versus condom-loaded Foley’s catheter for treatment of atonic postpartum hemorrhage secondary to vaginal delivery: a randomized controlled trial. The Journal Of Maternal-Fetal & Neonatal Medicine, 31(6), 747-753.
Ercole, F. F., Melo, L. S., & Alcoforado, C. L. G. C. (2014) Revisão integrativa versus revisão sistemática. Revista Mineira de Enfermagem, 18(1), 9-11.
Escobar, M. F., Pérez, P. A. F., Carvajal, J. A., Burgos, J. M., Messa, A., Echavarria, M. P., . . . & Hurtado, D. F. (2020). Impact of nonpneumatic antishock garment in the management of patients with hypoperfusion due to massive postpartum hemorrhage. The Journal Of Maternal-Fetal & Neonatal Medicine, 33(18), 3086-3090.
Feduniw, S., Warzecha, D., Szymusik, I., & Wielgos, M. (2020). Epidemiology, prevention and management of early postpartum hemorrhage — a systematic review. Ginekologia Polska, 91(1), 38-44.
Felipe, A. C. C., Ansaloni, L. V. S., Martins, M. V., Sousa, M. J. D., & Oliveira, R. A. D. (2020). Fatores assistenciais que influenciam nos altos índices de mortalidade materna por hemorragia puerperal. Revista de Divulgação Científica Sena Aires, 9(3), 551-562.
Finlayson, K., Downe, S., Vogel, J.P., & Oladapo, O. T. (2019). What matters to women and healthcare providers in relation to interventions for the prevention of postpartum haemorrhage: A qualitative systematic review. PLoS ONE, 2019. 14 (5), e0215919.
Gallos, I. D., Williams, H. M., Price, M. J., Merriel, A., Gee, H., Lissauer, D., . . . & Coomarasamy, A. (2018). Uterotonic agents for preventing postpartum haemorrhage: a network meta-analysis. Cochrane Database Of Systematic Reviews, 1-362.
Gaucher, L., Occelli, P., Deneux-Tharaux, C., Colin, C., Gaucherand, P., Touzet, S., & Dupont, C. (2019). Non-clinical interventions to prevent postpartum haemorrhage and improve its management: a systematic review. European Journal Of Obstetrics & Gynecology And Reproductive Biology, 240, 300-309.
Kellie, F. J., Wandabwa, J. N., Mousa, A. H., Weeks, A. D. (2020). Mechanical and surgical interventions for treating primary postpartum haemorrhage. Cochrane Database Of Systematic Reviews, 1-91.
Kuzume, A., Sugimi, S., Suga, S., Yamashita, H., & Yasuhi, I. (2017). The Routine Use of Prophylactic Oxytocin in the Third Stage of Labor to Reduce Maternal Blood Loss. Journal Of Pregnancy, 2017, 3274901.
Liabsuetrakul, T., Choobun, T., Islam, M., & Peeyananjarassri, K. Prophylactic use of ergot alkaloids in the third stage of labour. Cochrane Database Of Systematic Reviews, 1-62.
Lin, J., Lin, F., & Zhang, Y. (2019). Uterine artery ligation before placental delivery during caesarean in patients with placenta previa accreta. Medicine, 98(36), 16780.
Lumbreras-Marquez, M. I., Reale, S. C., Carusi, D. A., Robinson, J. N., Scharf, N., Fields, K. G., & Farber, M. K. (2020). Introduction of a Novel System for Quantitating Blood Loss After Vaginal Delivery. Anesthesia & Analgesia, 130(4), 857-868.
Maged, A. M., Waly, M., Fahmy, R. M., Dieb, A. S., Essam, A., Salah, N. M., Hussein, E. A., & Nabil, H. (2019). Carbetocin versus rectal misoprostol for management of third stage of labor among women with low risk of postpartum hemorrhage. International Journal Of Gynecology & Obstetrics, 148(2), 238-242.
Martins, A. C. S., & Silva, L. S. (2018). Perfil epidemiológico da mortalidade materna. Revista Brasileira de Enfermagem, 71, 677-683.
Mbaruku, G., Therrien, M. S., Tillya, R., Mbuyita, S., Mtema, Z., Kinyonge, I., . . . & Miller, S. (2018). Implementation project of the non-pneumatic anti-shock garment and m-communication to enhance maternal health care in rural Tanzania. Reproductive Health, 15, 177.
Meade-Treviño, P. F., Fernández-Lara, J. A., Lizaola-Díaz de Leon, H., Mendoza-Mares, R, & Grimaldo-Valenzuela, P. M. (2021). Vestuário anti-choque não pneumático: uma intervenção valiosa no tratamento de uma paciente com hemorragia obstétrica. Ginecología y Obstetricia de México, 86(3), 200-207.
Oladapo, O. T., Okusanya, B. O., & Abalos, E. (2018). Intramuscular versus intravenous prophylactic oxytocin for the third stage of labour. Cochrane Database Of Systematic Reviews, 1-37.
Oliveira, F. B. M., Costa, A. C. A. L., Alves, D. L., De França, J. F., Macedo, M. S., & Santos, R. D. (2016). Relação entre a sobrecarga de trabalho e erros de administração de medicação na assistência hospitalar. ReonFacema, 2(2):325-334.
Oliveira, R. C., & Davim, R. M. B. (2019). Prevenção e tratamento da hemorragia pós-parto. Rev Enferm Ufpe, 13, 236-248.
Pacheco, L. D., Hankins, G. D. V., Saad, A. F., Costantine, M. M., Chiossi, G., Saade, G. R. (2017). Tranexamic Acid for the Management of Obstetric Hemorrhage. Obstetrics & Gynecology, 130(4), 765-769.
Quibel, T., Ghout, I., Goffinet, F., Salomon, L. J., Fort, J., Javoise, S., . . . & Rozenberg, P. (2016). Active Management of the Third Stage of Labor With a Combination of Oxytocin and Misoprostol to Prevent Postpartum Hemorrhage. Obstetrics & Gynecology, 128, (4), 805-811.
Rangel, R. C. T., Souza, M. L., Bentes, C. M. L., Souza, A. C. R. H., Leitão, M. N. C., & Lynn, F. A. (2019). Tecnologias de cuidado para prevenção e controle da hemorragia no terceiro estágio do parto: revisão sistemática. Rev. Latino-Americana de Enfermagem, 27, 3165.
Salati, J. A., Leathersich, S. J., Williams, M. J., Cuthbert, A., & Tolosa, J. (2019). Prophylactic oxytocin for the third stage of labour to prevent postpartum haemorrhage. Cochrane Database Of Systematic Reviews, 1-95.
Sanad, A S., Mahran, A. E., Aboulfotouh, M. E., Kamel, H. H., Mohammed, H. F., Bahaa, . . . & Shawki, H. E.-D. (2018). The effect of uterine artery ligation in patients with central placenta pevia: a randomized controlled trial. Bmc Pregnancy And Childbirth, 18, 351.
Şentürk, Ş., Kağđtçđ, M., Balđk, G., Arslan, H., & Şahin, F. K. (2016). The Effect of the Combined Use of Methylergonovine and Oxytocin during Caesarean Section in the Prevention of Post-partum Haemorrhage. Basic & Clinical Pharmacology & Toxicology, 118(5), 338-343.
Suarez, S., Conde-Agudelo, A., Borovac-Pinheiro, A., Suarez-Rebling, D., Eckardt, M., Theron, G., & Burke, T. F. (2020). Uterine balloon tamponade for the treatment of postpartum hemorrhage: a systematic review and meta-analysis. American Journal Of Obstetrics And Gynecology, 222(4), 293.
Woman, T. C., Shakur, H., Roberts, I., Fawole, B., Chaudhri, R., El-Sheikh, M., . . . & Abdulkadir, A. (2017). Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial. The Lancet, 389(10084), 2105-2116.
World Health Organization. (2018). World Health Organization multicountry survey on maternal and newborn health. Geneva: WHO.
Wu, Y., Wang, H., Wu, Q.-Y., Liang, X.-L., & Wang, J. (2020). A meta-analysis of the effects of intramuscular and intravenous injection of oxytocin on the third stage of labor. Archives Of Gynecology And Obstetrics, 301(3), 643-653.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2021 Melissa Torres Soares Rabêlo; Ana Carla Marques da Costa; Amanda Kauany Pereira da Silva ; Joyce Soares de Araújo; Kessya Karynne de Araújo Silva; Lara Beatriz de Sousa Coelho; Eduardo Brito da Silva; Luana Pereira Ibiapina Coêlho ; Jesineide Sousa da Silva; Adriana Borges Ferreira da Silva ; Larissa Lima Marques Coimbra; Rosinei Nascimento Ferreira ; Pedro Vitor Mendes Santos; Eudilene da Silva Mesquita; Jeíse Rodrigues Belarmino
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.