The use of non-invasive neuromodulation in patients with cerebral palsy: potentializing neuroplasticity: integrative review

Authors

DOI:

https://doi.org/10.33448/rsd-v11i5.27596

Keywords:

Cerebral palsy; Transcranial direct current stimulation; Transcranial magnetic stimulation; Neuromodulation.

Abstract

Introduction: Cerebral Palsy (CP) is a group of non-progressive childhood neurological disorders that affect children and newborns, being the most common cause of disability in childhood. There are several treatments that can improve the quality of life for patients, but there are few treatments that focus on the structures around the lesion. Non-invasive Neuromodulation (NMNI) has been considered an innovative technology with beneficial results in neurological disorders, through the techniques Transcranial Direct Current Stimulation (TDCS) and Transcranial Magnetic Stimulation (TMS). Objective: To analyze through published works whether the NMNI has the capacity to potentiate neuroplasticity in patients with CP. Method: This work used the integrative review method using keywords “Continuous Transcranial Current Smulation”, “Transcranial Magnetic Stimulaton”, “Repetitive Trascranial Magnetic Stimulaton”, “Cerebral Palsy”, “Transcranial Direct Current Stimulation” and “Cerebral Palsy”. The surveys were selected between the year 2016 and 2021 in the PubMED, Google Scholar and Virtual Health Library (BVS) databases. Results: NMNI is used as a treatment associated with another technique, having results in the increase and decrease of brain waves, improving gait speed and quality, balance, mobility, cognition, language, spasticity reduction, potentiating the effects for longer. Conclusion: NMNI through TDCS and TMS is able to prolong the effects obtained when associated with another technique, having repercussions on the functional and cognitive capacity of patients with CP, studies are still recent, especially when the target group is children, but studies have shown benefits.

References

Alecastro, A. S. (2016). Estimulação Transcraniana por Corrente Contínua: Efeitos sobre a Memória Operacional de Idosos. 92 f., il. Dissertação (Mestrado em Ciências da Saúde). Universidade de Brasília, Brasília.

Auvichayapat, P., Aree-uea, B., Auvichayapat, N., Phuttharak, W., Janyacharoen, T., Tunkamnerdthai, O., Boonphongsathian, W., Ngernyam, N., & Keeratitanont, K. (2017). Transient Changes in Brain Metabolites after Transcranial Direct Current Stimulation in Spastic Cerebral Palsy: a pilot study. Frontiers In Neurology, 8 31, 1-9.

Bento, M. N. (2016). Efeitos da Estimulação Elétrica Transcraniana na Motricidade de Crianças com Paralisia Cerebral: uma Revisão Sistemática. Repositório Institucional da UFBA.

Bhatia, D., Rajak, B., Gupta, M., & Mukherjee, A. (2019). Increasing Number of Therapy Sessions of Repetitive Transcranial Magnetic Stimulation Improves Motor Development by Reducing Muscle Spasticity in Cerebral Palsy Children. Annals Of Indian Academy Of Neurology, (22) 3 302.

Carlson, H. L., Ciechanski, P., Harris, A. D., Macmaster, F. P., & Kirton, A. (2018). Changes in Spectroscopic Biomarkers After Transcranial Direct Current Stimulation in Children With Perinatal Stroke. Brain Stimulation, 11 (1) 94-103, jan.

Carvalho, M. S., Ribeiro Y. J. S., Beckman C. K. C., Sousa I. T. C., Pestana A. M., Jural, L. A., Ribeiro C. C. C., & Nunes A. M. M. (2020). Avaliação da Experiência Odontológica Prévia, Hábitos Alimentares e de Higiene Bucal em Pacientes com Paralisia Cerebral. Revista Rede de Cuidados em Saúde, 14 (2)

Chagas, P. S. C., Peixoto, J. G., Ortis, M. D. C., Ribeiro, L. C., Alves, J. W. F., & Defilipo, E. C. (2019). Comprimento de Isquiotibiais, Função Motora Grossa e Marcha em Crianças e Adolescentes com Paralisia Cerebral. Fisioterapia e Pesquisa, 26 (4), 366-372.

Cominetti, E. P. A., Gerzson, L. R., Almeida, C. S. (2020). Aplicação da Escala Spinal Alignment and Range of Motion Measure (SAROMM) em Crianças e Adultos com Paralisia Cerebral, em uma instituição de abrigagem de Porto Alegre (RS). Fisioterapia e Pesquisa, 27 (3) 277-286.

Croarkin, P. E., Macmaster, F. P. (2019). Transcranial Magnetic Stimulation for Adolescent Depression. Child And Adolescent Psychiatric Clinics Of North America, 28 (1) 33-43.

De Sousa, L. M. M., Marques-Vieira, C. M. A., Severino, S. S. P., & Antunes, A. V. (2017). A Metodologia de Revisão Integrativa da Literatura em Enfermagem. Revista investigação em enfermagem, 21(2), 17-26.

De Sousa, L. M. M., Firmino, C. F., Marques-Vieira, C. M. A., Severino, S. S. P., & Pestana, H. C. F. C. (2018). Revisões da Literatura Científica: tipos, métodos e aplicações em enfermagem. Revista Portuguesa de Enfermagem de Reabilitação, 1(1), 45-54.

Duarte, N. A. C. (2017). Efeitos das Diferentes Montagens da Estimulação Transcraniana por Corrente Contínua na Funcionalidade de Crianças com Paralisia Cerebral: ensaio clínico aleatorizado, placebo-controlado e duplo cego. 133 f. Tese (Programa de Pós-Graduação em Ciências da Reabilitação) - Universidade Nove de Julho.

Ferreira, M. T. S. (2016). Incidência de Crianças com Paralisia Cerebral Atendidas na Clínica Escola de Fisioterapia da Unicatólica. Revista Expressão Católica Saúde 1 (1).

Grecco, L. A. C., Oliveira, C. S., Duarte, N. A. C., Lima, V. L. C. C., Zanon, N., & Fregni, F. (2016). Cerebellar Transcranial Direct Current Stimulation in Children With Ataxic Cerebral Palsy: a sham-controlled, crossover, pilot study. Developmental Neurorehabilitation, 20 (3) 142-148.

Grecco, L., Oliveira, C., Galli, M., Cosmo, C., Duarte, N. A., Zanon, N., Edwards, D. J., & Fregni, F. (2016). Spared Primary Motor Cortex and The Presence of MEP in Cerebral Palsy Dictate the Responsiveness to tDCS during Gait Training. Front Hum Neurosci. 19 (10) 361.

Gupta M., Bhatia D. (2017) Effect of Repetitive Transcranial Magnetic Stimulation on Cognition in Spastic Cerebral Palsy Children. J Neurol Disord (5) 339.

Gupta, M., Bhatia, D. (2018) Evaluating the Effect of Repetitive Transcranial Magnetic Stimulation in Cerebral Palsy Children by Employing Electroencephalogram Signals. Ann Indian Acad Neurol. 21 (4) 280-284.

Gupta, M., Rajak, B. L., Bhatia, D., & Mukherjee, A. (2016). Effect of r-TMS Over Standard Therapy in Decreasing Muscle Tone of Spastic Cerebral Palsy Patients. Journal Of Medical Engineering & Technology, 40 (4) 210-216.

Gupta, M., Rajak, B. L., Bhatia, D., & Mukherjee, A. (2018). Neuromodulatory Effect of Repetitive Transcranial Magnetic Stimulation Pulses on Functional Motor Performances of Spastic Cerebral Palsy Children. Journal Of Medical Engineering & Technology, 42 (5) 352-358.

Hameed, M. Q., Dhamne, S. C., Gersner, R., Kaye, H. L., Oberman, L. M., Pascual-leone, A., & Rotenberg, A. (2017). Transcranial Magnetic and Direct Current Stimulation in Children. Current Neurology And Neuroscience Reports,17 (2) 1-25.

Inguaggiato, E., Bolognini, N., Fiori, S., & Cioni, G. (2019). Transcranial Direct Current Stimulation (tDCS) in Unilateral Cerebral Palsy: a pilot study of motor effect. Neural Plasticity, (2019) 1-10

Ko, E. J., Hong, M. J., Choi, E. J., Yuk, J. S., Yum, M. S., & Sung, I. Y. (2021). Effect of Anodal Transcranial Direct Current Stimulation Combined With Cognitive Training for Improving Cognition and Language Among Children With Cerebral Palsy With Cognitive Impairment: a pilot, randomized, controlled, double-blind, and clinical trial. Frontiers In Pediatrics, 9 (25) 1-10,

Lazzari, R. D., Politti, F., Belina, S. F., Grecco, L. A. C., Santos, C. A., Dumont, A. J. L., Lopes, J. B. P., Cimolin, V., Galli, M., & Oliveira, C. S. (2016). Effect of Transcranial Direct Current Stimulation Combined With Virtual Reality Training on Balance in Children With Cerebral Palsy: a randomized, controlled, double-blind, clinical trial. Journal Of Motor Behavior, 49 (3) 329-336.

Li, X., Song, G., Yu, J., Ai, S., Ji, Q., Peng, Y., Zhu, X., & Liu, J. (2021). Effectiveness and Safety of Repetitive Transcranial Magnetic Stimulation for The Treatment of Morphine Dependence. Medicine, 100 (14) 25208.

Lima, V. L. C. C., Grecco, L. A. C., Marques, V. C., Fregni, F., & Ávila, C. R. B. (2016). Transcranial Direct Current Stimulation Combined With Integrative Speech Therapy in a Child With Cerebral Palsy: a case report. Journal Of Bodywork And Movement Therapies, 20 (2) 252-257.

MarzbanI, H., Parvin, Sh., Amiri, S., Lotfian, M., Kharazi, M. R., Azizi, Sh., & Mirbagheri, M. M. (2016). The Correlation Between Transcranial Magnetic Stimulation Parameters and Neuromuscular Properties in Children With Cerebral Palsy. Annual International Conference Of The Ieee Engineering In Medicine And Biology Society (Embc), 5473-5476.

Matsuda, R. H., Tardelli, G. P., Guimarães, C. O., Souza, V. H., & Baffa F. (2019). O Estimulação Magnética Transcraniana: uma breve revisão dos princípios e aplicações. Revista Brasileira de Física Médica, 13, (1).

Miranda, V. S. G., Silveira, K. A., Rech, S. T., & Vidor, D. C. G. M. (2021). Comunicação Aumentativa e Alternativa e Habilidades de Linguagem de Crianças com Paralisia Cerebral: uma revisão sistemática. Revista Brasileira de Educação Especial, 27 1-14.

Moura, M. C. D. S., Hazime, F. A., Aparicio, L. V. M., Grecco, L. A. C., Brunoni, A. R., & Hasue, R. H. (2019). Effects of Transcranial Direct Current Stimulation (tDCS) on Balance Improvement: a systematic review and meta-analysis. Somatosensory & Motor Research, 36 (2), 122-135.

Nemanich, S. T., Chen, C., Chen, M., Zorn, E., Mueller, B., Peyton, C., Elison, J. T., Stinear, J., Rao, R., & Georgieff, M. (2019) Safety and Feasibility of Transcranial Magnetic Stimulation as an Exploratory Assessment of Corticospinal Connectivity in Infants After Perinatal Brain Injury: an observational study. Physical Therapy, 99 (6) 689-700.

Parvin, S., Shahrokhi, A., Tafakhori, A., Irani, A., Rasteh, M., & Mirbagheri, M. M. (2018). Therapeutic Effects of repetitive Transcranial Magnetic Stimulation on Corticospinal Tract Activities and Neuromuscular Properties in Children with Cerebral Palsy. Annual International Conference Of The Ieee Engineering In Medicine And Biology Society (Embc), 1-4.

Pereira, H. V. (2018) Residência Pediátrica. Revista do Pediatra, 49-55.

Silva Júnior, H. B. (2017) Pesquisadores em Estimulação Magnética Transcraniana no Brasil. Dissertação (Mestrado em Ciências da Saúde) - Universidade Federal de Goiás. 46

Silva, A. C. M., Schuffner, L. R., & Pereira, R. G. B. (2020) O Efeito da Estimulação Transcraniana por Corrente Contínua em Crianças com Paralisia Cerebral. Saúde do Vales, 1 2674-8584.

Silva, L. V. D. C. Respostas Fisiológicas do Exercício Concorrente Associado à ETCC em Idosos. (2016). 93 f. Dissertação (Mestrado em Ciências do Cuidado em Saúde) - Escola de Enfermagem Aurora de Afonso Costa, Universidade Federal Fluminense, Niterói.

Tekgul, H., Saz, U., Yilmaz, S., Polat, M., Aktan, G., Kose, T., Kitis, O., & Gokben, S. (2020). A transcranial magnetic stimulation study for the investigation of corticospinal motor pathways in children with cerebral palsy. Journal Of Clinical Neuroscience, 78 153-158.

Zhang, W., Zhang, S., Zhu, M., Tang, J., Zhao, X., Wang, Y., Liu, Y., Zhang, L., & Xu, H. (2021) Changes of Structural Brain Network Following Repetitive Transcranial Magnetic Stimulation in Children With Bilateral Spastic Cerebral Palsy: a diffusion tensor imaging study. Frontiers In Pediatrics. 8 1-12.

Published

02/04/2022

How to Cite

NOGUEIRA, V. da S. .; CARVALHO, D. F. de .; SANTOS, K. P. R. dos .; COUTINHO, E. N. .; MOURA, G. de S. .; SOUSA, A. L. S. de .; REIS, M. R. dos .; SANTOS, T. de O. .; SILVA, D. L. R. da .; PACHECO, K. . M. L. .; SANTOS, N. M. da C. dos . The use of non-invasive neuromodulation in patients with cerebral palsy: potentializing neuroplasticity: integrative review. Research, Society and Development, [S. l.], v. 11, n. 5, p. e17911527596, 2022. DOI: 10.33448/rsd-v11i5.27596. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/27596. Acesso em: 26 dec. 2024.

Issue

Section

Review Article