Mortality due to malformations of the circulatory system in children under 1 year of age in the Southeast region of Brazil between 2014 and 2019
DOI:
https://doi.org/10.33448/rsd-v11i5.27993Keywords:
Congenital Abnormalities; Cardiovascular System; Mortality; Child.Abstract
Objective: To analyze the mortality rates due to congenital malformations in the circulatory system in children younger than 1 year in the Southeast region of Brazil between 2014 and 2019. Methods: This is an ecological time series study carried out through the quantitative and qualitative analysis of the sample composed of deaths of children under 1 year old, as a result of congenital malformations in the circulatory system, in the Southeast region of Brazil in the period between 2014 and 2019. Data were collected from the Mortality Information System (SIM), made available through the Informatics Department of the Unified Health System (DATASUS). All notifications made during the six-year period studied were included and information not computed by the SIM was excluded. The analysis of epidemiological aspects was based on the following variables: year of death, Federation Unit (UF), place of occurrence, color/race and sex. Results: A total of 9,884 deaths were computed, distributed with little variation between the years observed. Of these, 51.82% occurred in the state of São Paulo; 94.55% in a hospital environment; 62.09% in children of color/white race and 53.3% in male children. Conclusion: The present study elucidated and related the epidemiological aspects of deaths from congenital malformations in the circulatory system in children under 1 year of age between 2014 and 2019, thus contributing to the recognition of the impact of these conditions on the child's life and the importance of early diagnostic measures in reducing mortality.
References
Agarwal, U., Smith, A. W., French, K. M., Boopathy, A. V., George, A., Trac, D., Brown, M. E., Shen, M., Jiang, R., Fernandez, J. D., Kogon, B. E., Kanter, K. R., Alsoufi, B., WagneR, M. B., Platt, M. O., & Davis, M. E. (2016). Age-Dependent Effect of Pediatric Cardiac Progenitor Cells After Juvenile Heart Failure. Stem Cells Translational Medicine, 5(7), 883–892. https://doi.org/10.5966/sctm.2015-0241
Bacaltchuk, T., Antunes, P., & Zielinsky, P. (2001). Rastreamento Pré-natal de Anormalidades Cardíacas: Papel da Ultra–sonografia Obstétrica de Rotina. Revista Brasileira de Ginecologia e Obstetrícia, 23(9), 553–558. https://doi.org/10.1590/s0100-72032001000900002
Brasil. (2022). Ministério da Saúde. Departamento de Informática do Sistema Único de Saúde (DATASUS). http://tabnet.datasus.gov.br/cgi/deftohtm.exe?sinasc/cnv/nvuf.def
Brum, C. A., Stein, A. T., & Pellanda, L. C. (2015). Infant Mortality in Novo Hamburgo: Associated Factors and Cardiovascular Causes. Arquivos Brasileiros de Cardiologia, 104(04), 257–265. https://doi.org/10.5935/abc.20140203
CID-10 (2013). Classificação estatística internacional de doenças e problemas relacionados à saúde. https://cid10.com.br/
D’Ovidio, C., Decembrino, L., Stronati, M., Carnevale, A., & Lattanzio, R. (2018). Anomalous Fusion of Right Pulmonary Artery to Aortic Arch: Case Report of a Rare and Fatal Congenital Malformation in a Newborn and a Literature Review. American Journal of Case Reports, 19, 1416–1421. https://doi.org/10.12659/AJCR.909749
Estrela, C. (2018). Metodologia Científica: Ciência, Ensino, Pesquisa (3a ed.). São Paulo: Artes Médicas.
Ferrari, R. A. P., & Bertolozzi, M. R. (2012). Mortalidade pós-neonatal no território brasileiro: uma revisão da literatura. Revista da Escola de Enfermagem da USP, 46(5), 1207–1214. https://doi.org/10.1590/S0080-62342012000500024
Freud, L. R., McElhinney, D. B., Kalish, B. T., Escobar-Diaz, M. C., Komarlu, R., Puchalski, M. D., Jaeggi, E. T., Szwast, A. L., Freire, G., Levasseur, S. M., Kavanaugh-Mchugh, A., Michelfelder, E. C., Moon-Grady, A. J., Donofrio, M. T., Howley, L. W., Tierney, E. S. S., Cuneo, B. F., Morris, S. A., Pruetz, J. D., Van Der Velde, M. E., Kovalchin, J. P., Ikemba, C. M., Vernon, M. M., Samai, C., Satou, G. M., Gotteiner, N. L., Phoon, C. K., Silverman, N. H. & Tworetzky, W. (2020). Risk Factors for Mortality and Circulatory Outcome Among Neonates Prenatally Diagnosed With Ebstein Anomaly or Tricuspid Valve Dysplasia: A Multicenter Study. Journal of the American Heart Association, 9(45), 1-15. https://doi.org/10.1161/JAHA.120.016684
IBGE. (2017). Censo Demográfico 2010. Conceitos e Métodos Rio de Janeiro. https://www.ibge.gov.br/estatisticas/sociais/populacao/9662-censo-demografico-2010.html
IBGE. (2020). Estatísticas do registro civil. Rio de Janeiro. https://www.ibge.gov.br/estatisticas/sociais/populacao/9110-estatisticas-do-registro-civil.html
IBGE. (2021). Estimativas da População. Rio de Janeiro. https://www.ibge.gov.br/estatisticas/sociais/populacao/9103-estimativas-de-populacao.html
Laurenti, R., Jorge, M. H. P. M., & Gotlieb, S. L. D. (2004). A confiabilidade dos dados de mortalidade e morbidade por doenças crônicas não-transmissíveis. Ciência & Saúde Coletiva, 9(4), 909–920. https://doi.org/10.1590/S1413-81232004000400012
Liu, M. Y., Zielonka, B., Snarr, B. S., Zhang, X., Gaynor, J. W., & Rychik, J. (2018). Longitudinal assessment of outcome from prenatal diagnosis through fontan operation for over 500 fetuses with single ventricle-type congenital heart disease: The Philadelphia Fetus-to-Fontan cohort study. Journal of the American Heart Association, 7(19), 1-19. https://doi.org/10.1161/JAHA.118.009145
Luo, L., Huang, P., Wang, T. T., Zhao, L. J., Ye, Z. W., Zhang, S. M., Chen, L. T., Diao, J. Y., Li, J. Q., Li, Y. H., & Qin, J. B. (2020). Association of maternal diabetes mellitus and UCP2 gene polymorphisms with congenital heart disease in offspring: A case-control study. Chinese Journal of Contemporary Pediatrics, 22(10), 1092-1099. https://doi.org/10.7499/j.issn.1008-8830.2004011
Mallmann, M. B., Boing, A. F., Tomasi, Y. T., Anjos, J. C. dos, & Boing, A. C. (2018). Evolution of socioeconomic inequalities in conducting prenatal consultations among Brazilian parturient women: analysis of the period 2000-2015. Epidemiologia e Serviços de Saúde: Revista Do Sistema Único de Saúde Do Brasil, 27(4), 1-11. https://doi.org/10.5123/S1679-49742018000400014
Nacher, M., Lambert, V., Favre, A., Carles, G., & Elenga, N. (2018). High mortality due to congenital malformations in children aged < 1 year in French Guiana. BMC Pediatrics, 18(1), 1-5. https://doi.org/10.1186/s12887-018-1372-8
Nguyen, K. L., Han, F., Zhou, Z., Brunengraber, D. Z., Ayad, I., Levi, D. S., Satou, G. M., Reemtsen, B. L., Hu, P., & Finn, J. P. (2017). 4D MUSIC CMR: value-based imaging of neonates and infants with congenital heart disease. Journal of Cardiovascular Magnetic Resonance, 19(1), 1-15. https://doi.org/10.1186/s12968-017-0352-8
Salim, T. R., Soares, G. P., Klein, C. H., & de Oliveira, G. M. M. (2016). Mortality from circulatory system diseases and malformations in children in the State of Rio de Janeiro. Arquivos Brasileiros de Cardiologia, 106(6), 464-473. https://doi.org/10.5935/abc.20160069
Victora, C. G., Aquino, E. M., do Carmo Leal, M., Monteiro, C. A., Barros, F. C., & Szwarcwald, C. L. (2011). Saúde de mães e crianças no Brasil: progressos e desafios. The Lancet, 377(9780), 32-46.
Wang, Z., Hao-Ming, S., Wang, F., Cui-Mei, Z., Ri-Tai, H., Xue, S., Ruo-Gu, L., Xing-Biao, Q., Ying-Jia, X., Xing-Yuan, L., & Yi-Qing, Y. (2019). A new ISL1 loss-of-function mutation predisposes to congenital double outlet right ventricle. International Heart Journal, 60(5), 1113-1122. https://doi.org/10.1536/ihj.18-685
Yang, Q., Wu, F., Mi, Y., Wang, F., Cai, K., Yang, X., Zhang, R., Liu, L., Zhang, Y., Wang, Y., Wang, X., Xu, M., Gui, Y., & Li, Q. (2020). Aberrant expression of miR-29b-3p influences heart development and cardiomyocyte proliferation by targeting NOTCH2. Cell Proliferation, 53(3), 1-16. https://doi.org/10.1111/cpr.12764
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Suzana Cássia Feltrin Alves; Frederico Augusto Oliveira Teixeira; Gabriela Andrade Franco; Giulia Isadora Cenci; Jessica Corrêa Pantoja; Lara Stephanie Aparecida de Souza Jacob; Diana Katalina Castaneda Vieira; Leonardo Marcondes Rodrigues; Juliana Sousa Candido; Érika Quinsan de Carvalho
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
