The impact of the telemedicine network on the epidemiology of congenital malformations in the state of Paraíba-Brazil: a comparison with worldwide incidences

Authors

DOI:

https://doi.org/10.33448/rsd-v11i7.30233

Keywords:

Congenital malformations; Epidemiology; Infant mortality; Telemedicine.

Abstract

Congenital anomalies are malformations observed in prepartum or after birth. They significantly impact infant mortality rates and represent a public health problem. The study aims to evaluate the impact of the implementation of a fully Paraíba telemedicine network on local epidemiology related to congenital malformations, comparing them to worldwide incidences. It is a retrospective descriptive study, based on the records of births and malformations, for two years (2018 and 2019). The incidence of the study was accounted for by 11.815 patients, of which 476 presented malformation, while the continental incidences were collected from the literature. The statistical analysis of the data was performed by the T-Test and the One-way ANOVA test. There was a predominance of cardiac (30%), musculoskeletal (15%) and genito-urinary tract (13.9%) malformations. The statistical comparison of the malformations in Paraíba with the continental data reflected similarity with the Asian (p-value = 0,03037), African (p-value = 0,03327) and European (p-value = 0,04787) continents. The comparison of the population averages measured that the data of Paraíba, tied to the world data, is statistically within an acceptable pattern (p-value = 0,041638). The high incidence of malformations reported is possibly due to the local screening methods adopted associated with the telemedicine adopted by the Rede Cuidar. The similarity with developing continents denotes a reality of the impact of anomalies in these countries. The study was limited to the collection of continental data, related to the publication period of the selected studies and the grouped malformations.

References

Abbey, M., Oloyede, O. A., Bassey, G., Kejeh, B. M., Otaigbe, B. E., Opara, P. I., ... & Akani, C. I. (2017). Prevalence and pattern of birth defects in a tertiary health facility in the Niger Delta area of Nigeria. International journal of women's health, 9, 115.

Abeywardana, S., & Sullivan, E. A. (2008). Congenital anomalies in Australia 2002-2003. AIHW National Perinatal Statistics Unit.

Abulezz, T., Talaat, M., Elsani, A., & Allam, K. (2016). Congenital hand anomalies in Upper Egypt. Indian Journal of Plastic Surgery, 49(02), 206-213.

Ahmed, H., Akbari, H., Emami, A., & Akbari, M. R. (2017). Genetic overview of syndactyly and polydactyly. Plastic and reconstructive surgery Global open, 5(11).

Ajao, A. E., & Adeoye, I. A. (2019). Prevalence, risk factors and outcome of congenital anomalies among neonatal admissions in OGBOMOSO, Nigeria. BMC pediatrics, 19(1), 1-10.

Anderson, J. E., Cheng, Y., Stephenson, J. T., Saadai, P., Stark, R. A., & Hirose, S. (2018). Incidence of gastroschisis in California. JAMA surgery, 153(11), 1053-1055.

Araújo, J. S. S. (2016). O impacto de uma rede de telemedicina no enfrentamento da microcefalia no estado da Paraíba.

Araújo, J. S. S., Régis, C. T., Gomes, R. G. S., Silva, C. S., Abath, C. M. B., Mourato, F. A., & Mattos, S. S. (2014). Cardiopatia congênita no nordeste brasileiro: 10 anos consecutivos registrados no estado da Paraíba, Brasil. Rev Bras Cardiol, 27(1), 509-15.

Baldacci, S., Gorini, F., Santoro, M., Pierini, A., Minichilli, F., & Bianchi, F. (2018). Environmental and individual exposure and the risk of congenital anomalies: a review of recent epidemiological evidence. Epidemiol Prev, 42(3-4 Suppl 1), 1-34.

Blencowe, H., Kancherla, V., Moorthie, S., Darlison, M. W., & Modell, B. (2018). Estimates of global and regional prevalence of neural tube defects for 2015: a systematic analysis. Annals of the new York Academy of Sciences, 1414(1), 31-46.

Bremer, S., Kiess, W., Thome, U., Knuepfer, M., Buehligen, U., Vogel, M., ... & Rissmann, A. (2016). Prevalence of Gastroschisis, Omphalocele, Spina Bifida and Orofacial Clefts of Neonates from January 2000 to December 2010 in Leipzig, Saxony, Saxony-Anhalt and Germany. Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)), 80(2), 122-128.

Calderon, M. G., Santos, E. F. D. S., Abreu, L. C. D., & Raimundo, R. D. (2019). Increasing prevalence, time trend and seasonality of gastroschisis in São Paulo state, Brazil, 2005–2016. Scientific Reports, 9(1), 1-10.

Craig, E., Reddington, A., Adams, J., Dell, R., Jack, S., Oben, G., ... & Simpson, J. (2013). The Health of Children and Young People with Chronic Conditions and Disabilities in the South Island (2013).

Dewan, M. C., Rattani, A., Mekary, R., Glancz, L. J., Yunusa, I., Baticulon, R. E., ... & Warf, B. C. (2018). Global hydrocephalus epidemiology and incidence: systematic review and meta-analysis. Journal of neurosurgery, 130(4), 1065-1079.

Ekwochi, U., Asinobi, I. N., Osuorah, D. C. I., Ndu, I. K., Ifediora, C., Amadi, O. F., & Sunday Mba, G. (2018). Pattern of congenital anomalies in newborn: a 4-year surveillance of newborns delivered in a tertiary healthcare facility in the south-east Nigeria. Journal of tropical pediatrics, 64(4), 304-311.

França, E. B., Lansky, S., Rego, M. A. S., Malta, D. C., França, J. S., Teixeira, R., ... & Vasconcelos, A. M. N. (2017). Leading causes of child mortality in Brazil, in 1990 and 2015: estimates from the Global Burden of Disease study. Revista brasileira de Epidemiologia, 20, 46-60.

Gom, S., Grieve, A., & Velaphi, S. (2019). Characteristics and outcomes of neonates with gastroschisis managed in a public tertiary hospital in a developing country. South African Journal of Child Health, 13(4), 168-173.

Groisman, B., Bidondo, M. P., Duarte, S., Tardivo, A., Barbero, P., & Liascovich, R. (2018). Descriptive epidemiology of major structural congenital anomalies in Argentina. Medicina, 78(4), 252-257.

Guimarães, A. L. S., Barbosa, C. C., Oliveira, C. M. D., Maia, L. T. D. S., & Bonfim, C. V. D. (2020). Relationship of databases of live births and infant deaths for analysis of congenital malformations. Revista Brasileira de Saúde Materno Infantil, 19, 917-924.

Hansen, T., Henriksen, T. B., Bach, C. C., & Matthiesen, N. B. (2017). Congenital heart defects and measures of prenatal brain growth: a systematic review. Pediatric Neurology, 72, 7-18.

Huang, Y. H., Wu, Q. J., Chen, Y. L., Jiang, C. Z., Gong, T. T., Li, J., ... & Zhou, C. (2018). Trends in the prevalence of congenital hydrocephalus in 14 cities in Liaoning province, China from 2006 to 2015 in a population-based birth defect registry from the Liaoning Women and Children’s Health Hospital. Oncotarget, 9(18), 14472.

Impellizzeri, A., Giannantoni, I., Polimeni, A., Barbato, E., & Galluccio, G. (2019). Epidemiological characteristic of Orofacial clefts and its associated congenital anomalies: retrospective study. BMC Oral Health, 19(1), 1-14.

Jaruratanasirikul, S., Tangtrakulwanich, B., Rachatawiriyakul, P., Sriplung, H., Limpitikul, W., Dissaneevate, P., ... & Tantichantakarun, P. (2016). Prevalence of congenital limb defects: Data from birth defects registries in three provinces in Southern Thailand. Congenital anomalies, 56(5), 203-208.

Jiang, D., Wang, Q., Shi, Z., & Sun, J. (2020). Congenital anomalies of the kidney and urinary tract in children with congenital heart defects. Kidney and Blood Pressure Research, 45(2), 307-313.

Khoshnood, B., Loane, M., De Walle, H., Arriola, L., Addor, M. C., Barisic, I., ... & Dolk, H. (2015). Long term trends in prevalence of neural tube defects in Europe: population based study. Bmj, 351.

Köche, J. C. (2009). Fundamentos da metodologia científica: teoria da ciência e iniciação à pesquisa. In: Fundamentos da metodologia científica: teoria da ciência e iniciação à pesquisa.

Krzesinski, E. I., Geerts, L., & Urban, M. F. (2019). Neural tube defect diagnosis and outcomes at a tertiary South African hospital with intensive case ascertainment. South African Medical Journal, 109(9), 698-703.

Kumar, A., & Singh, K. (2014). Major congenital malformations of the gastrointestinal tract among the newborns in one of the English Caribbean Countries, 1993-2012. Journal of Clinical Neonatology, 3(4), 205.

Lamquami, S., Mamouni, N., Errarhay, S., Bouchikhi, C., & Banani, A. (2015). Antenatal diagnosis of isolated omphalocele. Pan African Medical Journal, 21(1).

Lawal, T. A., Yusuf, B., & Fatiregun, A. A. (2015). Knowledge of birth defects among nursing mothers in a developing country. African Health Sciences, 15(1), 180-187.

Liu, Y., Chen, S., Zühlke, L., Black, G. C., Choy, M. K., Li, N., & Keavney, B. D. (2019). Global birth prevalence of congenital heart defects 1970–2017: updated systematic review and meta-analysis of 260 studies. International journal of epidemiology, 48(2), 455-463.

Mat Bah, M. N., Sapian, M. H., Jamil, M. T., Abdullah, N., Alias, E. Y., & Zahari, N. (2018). The birth prevalence, severity, and temporal trends of congenital heart disease in the middle‐income country: a population‐based study. Congenital heart disease, 13(6), 1012-1027.

Mattos, S. D. S., Hazin, S. M. V., Regis, C. T., Araújo, J. S. S. D., Albuquerque, F. C. D. L., Moser, L. R. D. N., ... & Lima Filho, J. L. D. (2015). A telemedicine network for remote paediatric cardiology services in north-east Brazil. Bulletin of the World Health Organization, 93, 881-887.

Mirfazeli, A., Kaviany, N., Hosseinpoor, K., Aryaie, M., & Golalipour, M. J. (2018). Birth Defects in Northern Iran (2008–2013). Iranian Journal of Public Health, 47(3), 413.

Moorthie, S., Blencowe, H., Darlison, M. W., Lawn, J., Morris, J. K., Modell, B., ... & Yunnis, K. A. (2018). Estimating the birth prevalence and pregnancy outcomes of congenital malformations worldwide. Journal of community genetics, 9(4), 387-396.

Oben, G. L. M. (2015). Indicators for congenital anomalies in New Zealand (Doctoral dissertation, University of Otago). Acesso em 3 Out. 2021. https://ourarchive.otago.ac.nz/handle/10523/5521

Organização Mundial de Saúde. Congenital anomalies. Acesso em 9 Nov. 2021. https://www.who.int/news-room/fact-sheets/detail/congenital-anomalies

Panamonta, V., Pradubwong, S., Panamonta, M., & Chowchuen, B. (2015). Global birth prevalence of orofacial clefts: a systematic review. J Med Assoc Thai, 98(Suppl 7), S11-21.

Pasha, Y. Z., Vahedi, A., Zamani, M., Alizadeh-Navaei, R., & Pasha, E. Z. (2017). Prevalence of birth defects in Iran: A systematic review and meta-analysis. Archives of Iranian Medicine (AIM), 20(6).

Petit, F., Jourdain, A. S., Holder-Espinasse, M., Keren, B., Andrieux, J., Duterque-Coquillaud, M., ... & Escande, F. (2016). The disruption of a novel limb cis-regulatory element of SHH is associated with autosomal dominant preaxial polydactyly-hypertrichosis. European Journal of Human Genetics, 24(1), 37-43.

Peyvandi, S., Baer, R. J., Chambers, C. D., Norton, M. E., Rajagopal, S., Ryckman, K. K., ... & Steurer, M. A. (2020). Environmental and socioeconomic factors influence the live‐born incidence of congenital heart disease: a population‐based study in California. Journal of the American Heart Association, 9(8).

Porras, G. L., León, O. M., Molano, J., Quinceno, S. L., Pachajoa, H., & Montoya, J. J. (2016). Prevalencia de defectos congénitos en Risaralda, 2010-2013. Biomédica, 36(4), 556-563.

Robinson, R., Stavsky, M., Sade, M. Y., Krymko, H., Slanovic, L., Novack, V., ... & Levitas, A. (2019). Risk factors for congenital heart defects in two populations residing in the same geographic area: a long-term population-based study, Southern Israel. Cardiology in the Young, 29(8), 1040-1044.

Santos, E. P. D., Ferrari, R. A. P., Bertolozzi, M. R., Cardelli, A. A. M., Godoy, C. B. D., & Genovesi, F. F. (2016). Mortality among children under the age of one: analysis of cases after discharge from maternity. Revista da Escola de Enfermagem da USP, 50, 0390-0398.

Shin, H., Ahn, E., & Choi, E. J. (2020). Access to antenatal healthcare and the prevalence of oral clefts: a spatial analysis. European Journal of Oral Sciences, 128(2), 145-152.

Silva, J. H. D., Terças, A. C. P., Pinheiro, L. C. B., França, G. V. A. D., Atanaka, M., & Schüler-Faccini, L. (2018). Perfil das anomalias congênitas em nascidos vivos de Tangará da Serra, Mato Grosso, 2006-2016. Epidemiologia e Serviços de Saúde, 27.

Springer, A., Van Den Heijkant, M., & Baumann, S. (2016). Worldwide prevalence of hypospadias. Journal of pediatric urology, 12(3), 152-e1.

Stefani, R. R., Böckmann, B. S., Soska Baldissera, G. S., Scherer, M. H., Lüdtke, M., & Signor, N. D. (2018). Malformações congênitas: principais etiologias conhecidas, impacto populacional e necessidade de monitoramento. Acta méd. Porto Alegre, 155-84.

Vatankhah, S., Jalilvand, M., Sarkhosh, S., Azarmi, M., & Mohseni, M. (2017). Prevalence of congenital anomalies in Iran: A review article. Iranian journal of public health, 46(6), 733.

Wiig, U. S., Zahl, S. M., Egge, A., Helseth, E., & Wester, K. (2017). Epidemiology of benign external hydrocephalus in Norway—a population-based study. Pediatric Neurology, 73, 36-41.

Xu, L. L., Yuan, X. Q., Zhu, J., Li, X. H., Wang, Y. P., Zhou, G. X., ... & Yang, Y. (2011). Incidence and its trends on gastroschisis in some parts of China, 1996-2007. Zhonghua liu Xing Bing xue za zhi= Zhonghua Liuxingbingxue Zazhi, 32(3), 268-270.

Zhao, Q. M., Liu, F., Wu, L., Ma, X. J., Niu, C., & Huang, G. Y. (2019). Prevalence of congenital heart disease at live birth in China. The Journal of pediatrics, 204, 53-58.

Zhao, Z., Zhan, Y., Chen, W., Ma, X., Sheng, W., & Huang, G. (2019). Functional analysis of rare variants of Gata4 identified in Chinese patients with congenital heart defect. genesis, 57(11-12).

Published

29/05/2022

How to Cite

RAMOS, J. V. B.; SILVA, M. H. A. da; SOUSA, T. M. M. A. de; ARAÚJO, K. D. T. de; ARAÚJO, J. S. S. de. The impact of the telemedicine network on the epidemiology of congenital malformations in the state of Paraíba-Brazil: a comparison with worldwide incidences. Research, Society and Development, [S. l.], v. 11, n. 7, p. e41211730233, 2022. DOI: 10.33448/rsd-v11i7.30233. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/30233. Acesso em: 4 jul. 2022.

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Section

Health Sciences