LOW FODMAPs: role in irritable bowel syndrome





FODMAPs; LOW FODMAP; Irritable bowel syndrome; Microbiota; Dietary therapy.


The digestive system encloses a perfect symbiosis between the host and its microbiome. Any disturbance to its dynamics initiates pathological processes, as functional diseases, common to this system. This work was developed so as to understand irritable bowel syndrome, which is a functional disease, and so as to search the literature for the use of the LOW FODMAP diet as a nutritional strategy for the recovery of health in patients with this disease. Through a literature review, in which 3 the considerations and main information related to the topic were selected in articles and books, the FODMAPs, their concepts, characteristics and the food groups that contain them were studied; the way lifestyle and intestinal microbiota act as health modulators; and the functional disease known as irritable bowel syndrome, its pathophysiology, symptoms and possible treatments. Research in which LOW FODMAP dietary therapy was tested in patients with IBS showed a reduction in the disease severity score. Finally, it was concluded that the LOW FODMAP diet contributes to the relief of symptoms related to functional diseases and, especially, irritable bowel syndrome in acute crises.


Altobelli, E., del Negro, V., Angeletti, P., & Latella, G. (2017). Low-FODMAP Diet Improves Irritable Bowel Syndrome Symptoms: A Meta-Analysis. Nutrients, 9(9), 940. https://dx.doi.org/10.3390/nu9090940.

Barrett, J. S., Gibson, P. R. (2012). Fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAPs) and nonallergic food intolerance: FODMAPs or food chemicals? Therapeutic Advances in Gastroenterology, 5(4), 261–268. https://dx.doi.org/10.1177/1756283X11436241.

Bellini, M. et al (2020). LOW FODMAP Diet: Evidence, Doubts, and Hopes. Nutrients, 12(1), 148. https://dx.doi.org/10.3390/nu12010148.

Bischoff, S. C. et al. (2014). Intestinal permeability – a new target for disease prevention and therapy. BMC Gastroenterology, 14(1), 189. https://dx.doi.org/10.1186/s12876-014-0189-7.

Böhn, L. et al. (2015). Diet Low in FODMAPs Reduces Symptoms of Irritable Bowel Syndrome as Well as Traditional Dietary Advice: A Randomized Controlled Trial. Gastroenterology, 149(6), 1399-1407.e2. https://dx.doi.org/10.1053/j.gastro.2015.07.054.

Collen, A. (2016). 10% Humano: Como os micro-organismos são a chave para a saúde do corpo e da mente. Sextante.

Correia, A. M. R., Mesquita, A. (2014). Mestrados & Doutoramentos. Estratégias para a elaboração de trabalhos científicos: o desafio da excelência. (2nd ed.). VidaEconómica.

Costello, E. K. et al. (2009). Bacterial Community Variation in Human Body Habitats Across Space and Time. Science, 326(5960), 1694–1697. https://www.science.org/doi/10.1126/science.1177486.

Cozzolino, S. M. F. (2016). Biodisponibilidade de Nutrientes (5th ed.). Manole.

Cuomo, R. et al. (2014). Irritable bowel syndrome and food interaction. World Journal of Gastroenterology, 20(27), 8837–8845. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112903.

Dinan, T. G., Cryan, J. F. (2017). The Microbiome-Gut-Brain Axis in Health and Disease. Gastroenterology Clinics of North America, 46(1), 77–89. https://dx.doi.org/10.1016/j.gtc.2016.09.007.

Drossman, D. A. (2016). Functional Gastrointestinal Disorders: History, Pathophysiology, Clinical Features, and Rome IV. Gastroenterology, 150(6), 1262-1279.e2. https://dx.doi.org/10.1053/j.gastro.2016.02.032.

Dunlop, S. P. et al. (2006). Abnormal Intestinal Permeability in Subgroups of Diarrhea-Predominant Irritable Bowel Syndromes. The American Journal of Gastroenterology, 101(6), 1288–1294. https://dx.doi.org/10.1111/j.1572-0241.2006.00672.x.

Francesconi, C. F. (2012). Algoritmos diagnósticos da Fundação Roma para sintomas gastrointestinais comuns: apresentação. Arquivos de Gastroenterologia, 49(suppl 1), 6–8. https://dx.doi.org/10.1590/S0004-28032012000500002.

Gibson, P. R., Shepherd, S. J. (2010). Evidence-based dietary management of functional gastrointestinal symptoms: The FODMAP approach. Journal of Gastroenterology and Hepatology, 25(2), 252–258. https://dx.doi.org/10.1111/j.1440-1746.2009.06149.x.

Kamada, N., Chen, G. Y., Inohara, N., & Núñez, G. (2013). Control of pathogens and pathobionts by the gut microbiota. Nature Immunology, 14(7), 685–690. https://dx.doi.org/10.1038/ni.2608.

LEI No 8.234, DE 17 DE SETEMBRO DE 1991, (1991) (testimony of Brasil).

Liu, J., Chey, W. D., Haller, E., Eswaran, S. (2020). Low-FODMAP Diet for Irritable Bowel Syndrome: What We Know and What We Have Yet to Learn. Annual Review of Medicine, 71(1), 303–314. https://dx.doi.org/10.1146/annurev-med-050218-013625.

Lowe, A. W., & Moseley, R. H. (2014). Covering the Cover. Gastroenterology, 146(1), 1–4. https://dx.doi.org/10.1053/j.gastro.2013.11.019.

Machado, A. B. F., Moreira, A. P. B., Rosa, D. D., Peluzio, M. C. G., Teixeira, T. F. S. (2021). Microbiota Gastrintestinal evidências de sua influência na saúde e na doença (2nd ed.). Rubio.

Martins, A., Pequito, A., & Baltazar, A. L. (2020). Disbiose Intestinal e Síndrome do Intestino Irritável: efeito de uma dieta baixa em FODMAPs. Acta Portuguesa de Nutrição, 38–41. https://dx.doi.org/10.21011/apn.2020.2207.

Matos, S. P., & Macedo, P. D. G. (2015). Bioquímica dos alimentos Composição, Reações e Práticas de conservação (1st ed.). Érica.

Mohajeri, M. H. et al. (2018). The role of the microbiome for human health: from basic science to clinical applications. European Journal of Nutrition, 57(S1), 1–14. https://dx.doi.org/10.1007/s00394-018-1703-4.

Muir, J. G. et al. (2009). Measurement of Short-Chain Carbohydrates in Common Australian Vegetables and Fruits by High-Performance Liquid Chromatography (HPLC). Journal of Agricultural and Food Chemistry, 57(2), 554–565. https://dx.doi.org/10.1021/jf802700e.

Quigley, E. M. M. et al. (2016). World Gastroenterology Organisation Global Guidelines Irritable Bowel Syndrome. Journal of Clinical Gastroenterology, 50(9), 704–713. https://dx.doi.org/10.1097/MCG.0000000000000653.

Ribeiro, A. A., Langbehn, J. K., Diamante, N. A., Rhoden, S. a., Pamphile, J. A. (2014). MICROBIOMA HUMANO: UMA INTERAÇÃO PREDOMINANTEMENTE POSITIVA? Uningá, 19(1), 38–43. https://www.mastereditora.com.br/periodico/20140630_161746.pdf.

Souza, C, S. C., Souza, S. C., Evangelista, J. N., Ferreira, J. C. S. (2021). A importância da microbiota intestinal e seus efeitos na obesidade. Research, Society and Development, 10(6). http://dx.doi.org/10.33448/rsd-v10i6.16086.

Spiller, R. (2021). Impact of Diet on Symptoms of the Irritable Bowel Syndrome. Nutrients, 13(2), 575. https://dx.doi.org/10.3390/nu13020575.

Tuck, C. J., Muir, J. G., Barrett, J. S., Gibson, P. R. (2014). Fermentable oligosaccharides, disaccharides, monosaccharides and polyols: role in irritable bowel syndrome. Expert Review of Gastroenterology & Hepatology, 8(7), 819–834. https://dx.doi.org/10.1586/17474124.2014.917956.

Wexler, A. G., Goodman, A. L. (2017). An insider’s perspective: Bacteroides as a window into the microbiome. Nature Microbiology, 2(5), 17026. https://dx.doi.org/10.1038/nmicrobiol.2017.26.



How to Cite

BATISTA, M. de S. .; XAVIER, K. D. F. .; SILVA, M. C. da. LOW FODMAPs: role in irritable bowel syndrome. Research, Society and Development, [S. l.], v. 11, n. 9, p. e21011931803, 2022. DOI: 10.33448/rsd-v11i9.31803. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/31803. Acesso em: 19 aug. 2022.



Health Sciences