Metabolic syndrome and physical inactivity in adults: a case-control study

Authors

DOI:

https://doi.org/10.33448/rsd-v11i10.32523

Keywords:

Metabolic syndrome; Sedentary lifestyle; Abdominal obesity; Diabetes Mellitus type 2; Obesity; Sedentary behavior.

Abstract

The aim of the study was to evaluate the association of metabolic syndrome with physical inactivity. A case-control study was carried out, nested in a population-based cross-sectional. Adults aged 20 to 59 years old, of both sexes, residing in Dourados-MS constituted a sample. Cases involved 149 with three or more criteria: 1) blood pressure ≥ 130 x 85 mmHg or using antihypertensive drugs; 2) waist awareness ≥ 90 cm (men and ≥ 80 cm (women); 3) fasting blood glucose ≥ 100 mg/dl or using hypoglycemic drugs; 4) HDL < 40 mg/dl (men) and < 50 mg/dl (women); and 5) triglycerides ≥ 150 mg/dl or using lipid-lowering drugs. Controls were drawn among subjects who did not have metabolic syndrome (n = 152). Data analysis was performed using the following tests: T-Test, Fisher's Exact, Chi-Square and Unconditional Logistic Regression. The inactive and overweight individuals were 11 times more likely to have metabolic syndrome than active and of normal weight. Elderly mentioned four times more metabolic syndrome than younger; men reported twice as many syndrome than women; and those with less schooling, twice as many syndrome as more schooling. The study demonstrates a great need to expand public health policies that encourage the practice of physical activity, as well as improve the quality of the population's diet, in order to mitigate the risk of developing metabolic syndrome.

References

Associação Brasileira das Empresas de Pesquisas. (2013). Critério de Classificação Econômica Brasil 2015. https://abep.org.

Alberti, K. G., Eckel, R. H., Grundy, S. M., Zimmet, P. Z., Cleeman, J. I., Donato, K. A., & International Association for the Study of Obesity. (2009). Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation, 120(16), 1640-1645. https://doi.org/10.1161/CIRCULATIONAHA.109.192644

Alberti, K. G., & Zimmet, P. Z. (1998). Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabetic Medicine: a journal of the British Diabetic Association, 15, 539-553.

Alberti, K. G., Zimmet, P. Z., & Shaw, J. (2006). Metabolic syndrome – a new world-wide definition. A Consensus Statement from the International Diabetes Federation. Diabetic Medicine: a journal of the British Diabetic Association, 23, 469-480.

Alexander, C. M., Landsman, P. B., & Grundy, S. M. (2008). The influence of age and body mass index on the metabolic syndrome and its components. Diabetes, obesity & metabolism, 10, 246-250. https://doi.org/10.1111/j.1463-1326.2006.00695.x

Alizadeh, S., Ahmadi, M., Ghorbani Nejad, B., Djazayeri, A., & Shab-Bidar, S. (2018). Metabolic syndrome and its components are associated with increased chronic kidney disease risk: Evidence from a meta-analysis on 11 109 003 participants from 66 studies. The International Journal of Clinical Practice, 72(8), e13201. https://doi.org/10.1111/ijcp.13201

Beck-Nielsen, H. (Ed.). (2013). The metabolic syndrome: Pharmacology and Clinical Aspects. Wien: Springer.

Brasil. Ministério da Saúde. (2011). Orientação para coleta e análise de dados antropométricos em serviços de saúde. Brasília: Ministério da Saúde.

Brasil. Ministério da Saúde. (2018). Vigitel Brazil 2017: surveillance of risk and protective factors for chronic diseases by telephone survey: estimates of frequency and sociodemographic distribution of risk and protective factors for chronic diseases in the capitals of the 26 Brazilian states and the Federal District in 2017. Brasília: Ministério da Saúde.

Carvalho Vidigal, F., Bressan, J., Babio, N., & Salas-Salvadó, J. (2013). Prevalence of metabolic syndrome in Brazilian adults: a systematic review. BMC Public Health, 13, 1198. https://doi.org/10.1186/1471-2458-13-1198

Chobanian, A. V., Bakris, G. L., Black, H. R., Cushman, W. C., Green, L. A., Izzo, J. L., & National High Blood Pressure Education Program Coordinating Committee. (2003). Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension, 42(6), 1206-1252. https://doi.org/10.1161/01.HYP.0000107251.49515.c2

Chu, A. H., & Moy, F. M. (2014). Association between physical activity and metabolic syndrome among Malay adults in a developing country, Malaysia. Journal of Science and Medicine in Sport, 17, 195-200. https://doi.org/10.1016/j.jsams.2013.04.003

Cristi-Montero, C., & Rodríguez, R, F. (2014). Paradoja "activo físicamente pero sedentario, sedentario pero activo físicamente".: Nuevos antecedentes, implicaciones en la salud y recomendaciones. Revista médica de Chile, 142(1), 72-78. https://dx.doi.org/10.4067/S0034-98872014000100011

El Bilbeisi, A. H., Hosseini, S., & Djafarian, K. (2017). The Association between Physical Activity and the Metabolic Syndrome among Type 2 Diabetes Patients in Gaza Strip, Palestine. Ethiopian Journal of Health Sciences, 27(3), 273-282. https://doi.org/10.4314/ejhs.v27i3.9

Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. (2001). Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA, 285(19), 2486-2497. https://doi.org/10.1001/jama.285.19.2486

Fagerstrom, K. O. (1978). Measuring degree of physical dependence to tobacco smoking with reference to individualization of treatment. Addictive Behaviors, 3(3-4), 235-241. https://doi.org/10.1016/0306-4603(78)90024-2

Franca, S. L., Lima, S. S., & Vieira, J. R. (2016). Metabolic Syndrome and Associated Factors in Adults of the Amazon Region. PloS one, 11(12), e0167320. https://doi.org/10.1371/journal.pone.0167320

Gami, A., Witt, B., Howard, D., Erwin, P. J., Gami, L. A., Somers, V. K., & Montori, V. M. (2007). Metabolic syndrome and risk of incident cardiovascular events and death: a systematic review and meta-analysis of longitudinal studies. Journal of American College of Cardiology, 49(4), 403-414. https://doi.org/10.1016/j.jacc.2006.09.032

Hess, P. L., Al-Khalidi, H. R., Friedman, D. J., Mulder, H., Kucharska-Newton, A., Rosamond, W. R., … Al-Khatib, S. M. (2017). The Metabolic Syndrome and Risk of Sudden Cardiac Death: The Atherosclerosis Risk in Communities Study. Journal of American Heart Association, 6(8), e006103. https://doi.org/10.1161/JAHA.117.006103

International Physical Activity Questionnaine – IPAQ (2005). Guidelines for Data Processing and Analysis of the International Physical Activity Questionnaire (IPAQ). http://www.ipaq.ki.se

Kolovou, G. D., Anagnostopoulou, K. K., Salpea, K. D., & Mikhailidis, D. P. (2007). The prevalence of metabolic syndrome in various populations. American Journal of The Medical Sciences, 333(6), 362-371. https://doi.org/10.1097/MAJ.0b013e318065c3a1

Lakka, T. A., Laaksonen, D. E., Lakka, H.-M., Männikkö, N., Niskanen, L. K., Rauramma, R., & Salonen, J. T. (2003). Sedentary lifestyle, poor cardiorespiratory fitness, and the metabolic syndrome. Medicine & Science in Sports & Exercise, 35(8), 1279-1286. https://doi.org/10.1249/01.MSS.0000079076.74931.9A

Lee, W. Y., Jung, C. H., Park, J. S., Rhee, E. J., & Kim, S. W. (2005). Effects of smoking, alcohol, exercise, education, and family history on the metabolic syndrome as defined by the ATP III. Diabetes Research and Clinical Practice, 67, 70-77. https://doi.org/10.1016/j.diabres.2004.05.006

Levinger, I., Goodman, C., Hare, D. L., Jerums, G., & Selig, S. (2009). Functional capacity and quality of life in middle-age men and women with high and low number of metabolic risk factors. International Journal of Cardiology, 133(2), 281-283. https://doi.org/10.1016/j.ijcard.2007.11.046

Márquez-Sandoval, F., Macedo-Ojeda, G., Viramontes-Hörner, D., Ballart, J. F., Salvadó, J. S., & Vizmanos, B. (2011). The prevalence of metabolic syndrome in Latin America: a systematic review. Public Health Nutrition, 14(10), 1702-1713. https://doi.org/10.1017/S1368980010003320

Martin, A., Neale, E. P., Batterham, M., & Tapsell, L. C. (2016). Identifying metabolic syndrome in a clinical cohort: Implications for prevention of chronic disease. Preventive Medicine Reports, 4, 502-506. https://doi.org/10.1016/j.pmedr.2016.09.007

Matsudo, S., Araújo, T., Matsudo, V., Andrade, D., Andrade, E., Oliveira, L. C., ... Braggion, G. (2012). Questionário internacional de atividade física (IPAQ): estudo de validade e reprodutibilidade no Brasil. Revista Brasileira de Atividade Física & Saúde, 6(2), 5-18. https://doi.org/10.12820/rbafs.v.6n2p5-18

Menezes, A. P. (2011). Colônia Agrícola Nacional de Dourados – história, memória: considerações acerca da construção de uma memória oficial sobre a CAND na região da Grande Dourados. História em Reflexão, 5(9). https://ojs.ufgd.edu.br/index.php/historiaemreflexao/article/view/1165/697

Mohan, V., Gokulakrishnan, K., Deepa, R., Shanthirani, C. S., & Datta, M. (2005). Association of physical inactivity with components of metabolic syndrome and coronary artery disease--the Chennai Urban Population Study (CUPS no. 15). Diabetic Medicine, 22(9), 1206-1211. https://doi.org/10.1111/j.1464-5491.2005.01616.x

Moretti-Pires, R. O., & Corradi-Webster, C. M. (2011). Adaptation and validation of the Alcohol Use Disorders Identification Test (AUDIT) for a river population in the Brazilian Amazon. Cadernos de Saúde Pública, 27(3), 497-509. https://doi.org/10.1590/S0102-311X2011000300010

Mottillo, S., Filion, K. B., Genest, J., Joseph, L., Pilote, L., Poirier, P., & Eisenberg, M. J. (2010). The metabolic syndrome and cardiovascular risk a systematic review and meta-analysis. Journal of American College of Cardiology, 56(14), 1113-1132. https://doi.org/10.1016/j.jacc.2010.05.034

Olijhoek, J. K., van der Graaf, Y., Banga, J.-D., Algra, A., Rabelink, T. J., & Visseren, F. L. (2004). The metabolic syndrome is associated with advanced vascular damage in patients with coronary heart disease, stroke, peripheral arterial disease or abdominal aortic aneurysm. European Heart Journal, 25(4), 342-348. https://doi.org/10.1016/j.ehj.2003.12.007

Oliveira, L. V. A., Santos, B. N. S., Machado, I. E., Malta, D. C., Velasquez-Melendez, G. & Felisbino-Mendes, M. S. (2020). Prevalência da Síndrome Metabólica e seus componentes na população adulta brasileira. Ciência & Saúde Coletiva [online], 25 (11), 4269-4280. https://doi.org/10.1590/1413-812320202511.31202020

Pathak, R., Agarwalla, R., & Pathania, D. (2018). Assessment of metabolic syndrome and health related quality of life in community dwellers: A cross sectional study from North India. Indian Journal of Medical Specialities, 9(1), 15-19. https://doi.org/10.1016/j.injms.2018.01.001

Rampal, S., Mahadeva, S., Guallar, E., Bulgiba, A., Mohamed, R., Rahmat, R., & Rampal, L. (2012). Ethnic differences in the prevalence of metabolic syndrome: results from a multi-ethnic population-based survey in Malaysia. PloS one, 7(9), e46365. https://doi.org/10.1371/journal.pone.0046365

Reaven, G. M. (1988). Role of insulin resistance in human disease. Diabetes, 37(12), 1595-1607. https://doi.org/10.2337/diab.37.12.1595

Ren, H., Wang, J., Gao, Y., Yang, F., & Huang, W. (2019). Metabolic syndrome and liver-related events: a systematic review and meta-analysis. BMC Endocrine Disorders, 19(1), 40. https://doi.org/10.1186/s12902-019-0366-3

Saklayen, M. G. (2018). The Global Epidemic of the Metabolic Syndrome. Current Hypertension Reports, 20(2), 12. https://doi.org/10.1007/s11906-018-0812-z

Santos, A. C., Ebrahim, S., & Barros, H. (2007). Alcohol intake, smoking, sleeping hours, physical activity and the metabolic syndrome. Preventive Medicine, 44(4), 328-334. https://doi.org/10.1016/j.ypmed.2006.11.016

Santos, A. C., Ebrahim, S., & Barros, H. (2008). Gender, socio-economic status and metabolic syndrome in middle-aged and old adults. BMC Public Health, 8, 62. https://doi.org/10.1186/1471-2458-8-62

Shin, D., Kongpakpaisarn, K., & Bohra, C. (2018). Trends in the prevalence of metabolic syndrome and its components in the United States 2007-2014. International Journal of Cardiology, 259, 216-219. https://doi.org/10.1016/j.ijcard.2018.01.139

Thomas, G., Sehgal, A. R., Kashyap, S. R., Srinivas, T. R., Kirwan, J. P., & Navaneethan, S. D. (2011). Metabolic syndrome and kidney disease: a systematic review and meta-analysis. Clinical Journal of the American Society of Nephrology, 6(10), 2364-2373. https://doi.org/10.2215/CJN.02180311

Van Wormer, J. J., Boucher, J. L., Sidebottom, A. C., Sillah, A., & Knickelbine, T. (2017). Lifestyle changes and prevention of metabolic syndrome in the Heart of New Ulm Project. Preventive Medicine Reports, 6, 242-245. https://doi.org/10.1016/j.pmedr.2017.03.018

World Health Organization. (1995). Physical Status: the use and interpretation of anthropometry. Geneva: WHO.

World Health Organization. (2010). Global recommendations on physical activity for health. Geneva: WHO.

Wünsch, C., Zanovello, S. R., Iahnn, S. R., Andrade, G. R. B., & Lima, R. C. (2022). Association between hypertriglyceridemic waist phenotype and Diabetes mellitus in adults: a case-control study. Research, Society and Development, 11(6), e53711629328. https://doi.org/10.33448/rsd-v11i6.29328

Xiao, J., Shen, C., Chu, M. J., Gao, Y. X., Xu, G. F., Huang, J. P., & Cai, H. (2016). Physical Activity and Sedentary Behavior Associated with Components of Metabolic Syndrome among People in Rural China. PloS one, 11(1), e0147062. https://doi.org/10.1371/journal.pone.0147062

Zhu, S., McClure, L. A., Lau, H., Romero, J. R., White, C. L., Babikian, V., & Pikula, A. (2015). Recurrent vascular events in lacunar stroke patients with metabolic syndrome and/or diabetes. Neurology, 85(11), 935-941. https://doi.org/10.1212/WNL.0000000000001933

Published

30/07/2022

How to Cite

ZANOVELLO, S. R.; IAHNN, S. R.; FREITAS, G. A. de .; LIMA, R. da C. Metabolic syndrome and physical inactivity in adults: a case-control study . Research, Society and Development, [S. l.], v. 11, n. 10, p. e262111032523, 2022. DOI: 10.33448/rsd-v11i10.32523. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/32523. Acesso em: 5 nov. 2024.

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Section

Health Sciences