Aplicabilidad del uso terapéutico de probióticos en el sobrepeso: una revisión integrativa

Autores/as

DOI:

https://doi.org/10.33448/rsd-v11i12.34420

Palabras clave:

Microbiota; Obesidad; Probióticos; Biomarcadores.

Resumen

Objetivo: Describir la relación entre la disbiosis intestinal y el sobrepeso, destacando los efectos terapéuticos de los probióticos en el tratamiento de este cuadro clínico. Metodología: Se trata de una revisión bibliográfica integradora, con búsquedas en las bases de datos PubMed y Biblioteca Virtual en Salud (BVS), con el Sistema en Línea de Búsqueda y Análisis de Literatura Médica (MEDLINE) y Literatura Latinoamericana y del Caribe en Ciencias de la Salud (LILACS) indexadas en esta última base. Los descriptores utilizados para las búsquedas fueron: “microbiota’’, “obesity/obesity”, “probiotics/probiotics” y “biomarkers/biomarks” y los operadores booleanos AND/AND y OR/OR para el cruce de palabras. Se seleccionaron artículos originales de los últimos 10 años, con resúmenes y textos libres disponibles en su totalidad. Resultados: Fueron elegibles 12 artículos, que demostraron que varias cepas probióticas tienen efectos antiobesidad, reduciendo marcadores de adiposidad, como peso corporal, índice de masa corporal, tejido adiposo visceral, circunferencia de cintura y cadera, relación cintura/talla, porcentaje de grasa corporal y conicidad índice, ayudando así en la prevención y tratamiento del exceso de peso. Conclusión: La suplementación con probióticos, especialmente de algunas cepas específicas, es de gran relevancia para la prevención y tratamiento del sobrepeso, por lo que puede ser utilizada en la práctica clínica de los nutricionistas.

Citas

Agus, A., Denizot, J., Thévenot, J., Martinez-Medina, M., Massier, S., Sauvanet, P., Bernalier-Donadille, A., Denis, S., Hofman, P., Bonnet, R., Billard, E., & Barnich, N. (2016). Western diet induces a shift in microbiota composition enhancing susceptibility to Adherent-Invasive E. coli infection and intestinal inflammation. Scientific Reports, 6(19032), 1-14. https://doi.org/10.1038/srep19032.

Amon, P., & Sanderson, I. (2017). What is the microbiome?. Archives of disease in childhood. Education and practice edition, 102(5), 258-261. http://dx.doi.org/10.1136/archdischild-2016-311643.

Azad, M.A., Sarker, M., Li, T., & Yin, J. (2018). Probiotic species in the modulation of gut microbiota: an overview. Biomed research international, 2018, 1-8. https://doi.org/10.1155/2018/9478630.

Chooi, Y. C., Ding, C., & Magkos, F. (2018). The epidemiology of obesity. Metabolism: clinical and experimental, 92, 1-20. https://doi.org/10.1016/j.metabol.2018.09.005.

Déchelotte, P., Breton, J., Trotin-Picolo, C., Grube, B., Erlenbeck, C., Bothe, G., Fetissov, S. O., & Lambert, G. (2021). The Probiotic Strain H. alvei HA4597® Improves Weight Loss in Overweight Subjects under Moderate Hypocaloric Diet: A Proof-of-Concept, Multicenter Randomized, Double-Blind Placebo-Controlled Study. Nutrients, 13(6), 1-14. https://doi.org/10.3390/nu13061902.

De Melo, B. R., & De Oliveira, R. S. (2018). Prevalência de disbiose intestinal e sua relação com doenças crônicas não transmissíveis em estudantes de uma instituição de ensino superior de Fortaleza-CE. Revista Brasileira de Obesidade, Nutrição e Emagrecimento, 12(74), 767-775. http://www.rbone.com.br/index.php/rbone/article/view/790/592.

De Souza, M.T., Da Silva, M. D., & De Carvalho, R. (2010). Revisão integrativa; o que é e como fazer. Einstein (São Paulo), 8(1), 102-106. http://dx.doi.org/10.1590/s1679-45082010rw1134.

Food and Agriculture Organization of the United Nations., & World Health Organization. (2001). Health and Nutritional Properties of Probiotics in Food including Powder Milk with Live Lactic Acid Bacteria. http://pc.ilele.hk/public/pdf/20190225/bd3689dfc2fd663bb36def1b672ce0a4.pdf.

Higashikawa, F., Noda, M., Awaya, T., Danshiitsoodol, N., Matoba, Y., Kumagai, T., & Sugiyama, M. (2015). Antiobesity effect of Pediococcus pentosaceus LP28 on overweight subjects: a randomized, double-blind, placebo-controlled clinical trial. European journal of clinical nutrition, 70(5), 582-587. https://doi.org/10.1038/ejcn.2016.17.

Kadooka, Y., Sato, M., Ogawa, A., Miyoshi, M., Uenishi, H., Ogawa, H., Ikuyama, K., Kagoshima, M., & Tsuchida, T. (2013). Effect of Lactobacillus gasseri SBT2055 in fermented milk on abdominal adiposity in adults in a randomised controlled trial. The British journal of nutrition, 110(9), 1696-1703. https://doi.org/10.1017/s0007114513001037.

Kim, J., Yun, J. M., Kim, M. K., Kwon, O., & Cho, B. (2018). Lactobacillus gasseri BNR17 Supplementation Reduces the Visceral Fat Accumulation and Waist Circumference in Obese Adults: A Randomized, Double-Blind, Placebo-Controlled Trial. Journal of medicinal food, 21(5), 454-461. https://doi.org/10.1089/jmf.2017.3937.

Ley, R. E., Backhed, F., Turnbaugh, P., Lozupone, C. A, Knight, R. D., & Gordon, J. I. (2005). Obesity alters gut microbial ecology. Proceedings of the National Academy of Sciences of the United States of America, 102(31), 11070-11075. https://doi.org/10.1073/pnas.0504978102.

Lim, S., Moon, J. H., Shin, C. M., Jeong, D., & Kim, B. (2020). Effect of Lactobacillus sakei, a Probiotic Derived from Kimchi, on Body Fat in Koreans with Obesity: A Randomized Controlled Study. Endocrinology and metabolism, 35(2), 425-434. https://doi.org/10.3803/enm.2020.35.2.425.

Liu, B. N., Liu, X. T., Liang, Z. H., & Wang, J. H. (2021). Gut microbiota in obesity. World Journal of Gastroenterology, 27(25), 3837-3850. https://dx.doi.org/10.3748/wjg.v27.i25.3837.

Madjd, A., Taylor, M. A., Mousavi, N., Delavari, A., Malekzadeh, R., Macdonald, I. A., & Farshchi, H. R. (2016). Comparison of the effect of daily consumption of probiotic compared with low-fat conventional yogurt on weight loss in healthy obese women following an energy-restricted diet: a randomized controlled trial. The American journal of clinical nutrition, 103(2), 323-329. https://doi.org/10.3945/ajcn.115.120170.

Mendes, K. D., Silveira, R. C., & Galvão, C. M. (2008). Revisão integrativa: método de pesquisa para a incorporação de evidências na saúde e na enfermagem. Texto & Contexto- Enfermagem, 17(4), 758-764. https://doi.org/10.1590/S0104-07072008000400018.

Mentella, M. C., Scaldaferri, F., Pizzoferrato, M., Gasbarrini, A., & Miggiano, G. A. (2020). Nutrition, IBD and Gut Microbiota: A Review. Nutrients, 12(4), 1-20. https://doi.org/10.3390/nu12040944.

Michael, D. R., Jack, A. A., Masetti, G., Davies, T. S., Loxley, K. E., Kerry-Smith, J., Plummer, J. F., Marchesi, J. R., Mullish, B. H., McDonald, J. A., Hughes, T. R., Wang, D., Garaiova, I., Paduchová, Z., Muchová, J., Good, M. A., & Plummer, S. F. (2020). A randomised controlled study shows supplementation of overweight and obese adults with lactobacilli and bifidobacteria reduces bodyweight and improves well-being. Scientific reports, 10(1), 1-12. https://doi.org/10.1038/s41598-020-60991-7.

Michael, D. R., Davies, T. S., Jack, A. A., Masetti, G., Marchesi, J. R., Wang, D., Mullish, B. H., & Plummer, S. F. (2021). Daily supplementation with the Lab4P probiotic consortium induces signifcant weight loss in overweight adults. Scientific reports, 11(5), 1-8. https://doi.org/10.1038/s41598-020-78285-3.

Patterson, E., Ryan, P. M., Cryan, J. F., Dinan, T. G., Ross, R. P., Fitzgerald, G. F., & Stanton, C. (2016). Gut microbiota, obesity and diabetes. Postgraduate medical journal, 92(1087), 286-300. https://doi.org/10.1136/postgradmedj-2015-133285.

Pedret, A., Valls, R. M., Calderón-Pérez, L., Llauradó, E., Companys, J., Pla-Pagà, L., Moragas, A., Martín-Luján, F., Ortega, Y., Giralt, M., Caimari, A., Chenoll, E., Genovés, S., Martorell, P., Codoñer, F. M., Ramón, D., Arola, L., & Solà, R. (2018). Effects of daily consumption of the probiotic Bifidobacterium animalis subsp. lactis CECT 8145 on anthropometric adiposity biomarkers in abdominally obese subjects: a randomized controlled trial. International journal of obesity, 43(9), 1863-1868. https://doi.org/10.1038/s41366-018-0220-0.

Rahayu, E. S., Mariyatun, M., Manurung, N. E., Hasan, P. N., Therdtatha, P., Mishima, R., Komalasari, H., Mahfuzah, N. A., Pamungkaningtyas, F. H., Yoga, W. K., Nurfiana, D. A., Liwan, S. Y., Juffrie, M., Nugroho, A. E., & Utami, T. (2021). Effect of probiotic Lactobacillus plantarum Dad-13 powder consumption on the gut microbiota and intestinal health of overweight adults. World journal of gastroenterology, 27(1), 107-128. https://doi.org/10.3748/wjg.v27.i1.107.

Sanchez, M., Darimont, C., Drapeau, V., Emady-Azar, S., Lepage, M., Rezzonico, E., Ngom-Bru, C., Berger, B., Philippe, L., Ammon-Zuffrey, C., Leone, P., Chevrier, G., St-Amand, E., Marette, A., Doré, J., & Tremblay, A. (2014). Effect of Lactobacillus rhamnosus CGMCC1.3724 supplementation on weight loss and maintenance in obese men and women. The British journal of nutrition, 111(8), 1507-1519. https://doi.org/10.1017/s0007114513003875.

Sohn, M., Na, G. Y., Chu, J., Joung, H., Kim, B. K., & Lim, S. (2022). Efficacy and Safety of Lactobacillus plantarum K50 on Lipids in Koreans With Obesity: A Randomized, Double-Blind Controlled Clinical Trial. Frontiers in endocrinology, 12(790046), 1-10. https://doi.org/10.3389/fendo.2021.790046.

Stillwell, S. B., Fineout-Overholt, E., Melnyk, B. M., & Williamson, K. M. (2010). Evidence-based practice, step by step: searching for the evidence. The American jornal of nursing, 110(5): 41-47. https://doi.org/10.1097/01.naj.0000372071.24134.7e.

Tomasello, G., Mazzola, M., Leone, A., Sinagra, E., Zummo, G., Farina, F., Damiani, P., Cappello, F., Geagea, A.G., Jurjus, A., Assi, B. T., Messina, M., & Carini, F. (2016). Nutrition, oxidative stress and intestinal dysbiosis: Influence of diet on gut microbiota in inflammatory bowel diseases. Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia, 160(4), 461-466. https://doi.org/10.5507/bp.2016.052.

Ursi, E. S., & Galvão, C. M. (2006). Prevenção de lesões de pele no perioperatório: revisão integrativa de literatura. Revista Latino-Americana de Enfermagem, 14(1), 124-131. https://www.scielo.br/j/rlae/a/7hS3VgZvTs49LNX9dd85VVb/?lang=pt&format=pdf.

Vandenplas, Y., Huys, G., & Daube, G. (2015). Probiotics: an update. Jornal de Pediatria, 91(1), 6-21. https://doi.org/10.1016/j.jped.2014.08.005.

World Health Organization. (2021). Obesity and overweight. https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight.

Publicado

13/09/2022

Cómo citar

SOUZA, B. T. S. de .; SANTOS, I. M. A. dos; LIMA, T. C. R. M. . Aplicabilidad del uso terapéutico de probióticos en el sobrepeso: una revisión integrativa. Research, Society and Development, [S. l.], v. 11, n. 12, p. e243111234420, 2022. DOI: 10.33448/rsd-v11i12.34420. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/34420. Acesso em: 30 jun. 2024.

Número

Sección

Revisiones