Epidemiological analysis of meningitis cases in children in Brazil from 2010 to 2020
DOI:
https://doi.org/10.33448/rsd-v11i15.37032Keywords:
Meningitis; Epidemiology; Notification; Infectious disease.Abstract
Meningitis is a disease with a high fatality rate, requiring timely and appropriate diagnosis and treatment to avoid death and sequel. This disease can lead to lifelong disability for survivors. In this context, the objective of this research was to evaluate the epidemiological profile of meningitis cases in Brazil, diagnosed in children younger than 1 year and up to 9 years and 11 months, in the period from 2010 to 2020. The present research was carried out through a retrospective, quantitative study, with temporal secondary data collected from the DATASUS database according to the Notifiable Diseases Information System (SINAN). The variables evaluated were: age group, region of notification, sex, race, etiology and diagnostic method. Data were analyzed using descriptive statistics and were represented in the form of graphs. In Brazil between 2010 and 2020, 187,508 cases of meningitis were diagnosed, of which 87,939 corresponded to children under one year and up to 9 years and 11 months and 28,384 cases in children under 1 year. The Southeast region had the highest number of children and neonates with meningitis, and the lowest number in the North region. Viral meningitis prevailed over bacterial. Males and white and brown races were the most affected by the disease. The diagnostic criteria were: chemocytological, clinical, culture, PCR-viral, AG Latex, clinical-epidemiological and bacterioscopy.
References
Aguiar, T. S., Fonseca, M. C., Santos, M. C., Nicoletti, G. P., Alcoforado, D. S. G., Santos, S. C. D., Pontes, M. De L., Soares, T. F. R., Marcos, G. C., Teixeira, S. C. M., Macedo, B. M., Medeiros, L. N. B., Brandao, G. H. A., Câmara, A. G., Amorim, I. G., & Macêdo Júnior, A. M. de. (2022). Epidemiological profile of meningitis in Brazil, based on data from DataSUS in the years 2020 and 2021. Research, Society and Development, [S. l.], 11( 3): e50811327016.. http://dx.doi.org/10.33448/rsd-v11i3.27016.
Al-Qahtani, S. M., Shati, A. A., Alqahtani, Y. A., & Ali, A. S. (2022). Etiology, clinical phenotypes, epidemiological correlates, laboratory biomarkers and diagnostic challenges of pediatric viral meningitis: Descriptive review. Frontiers in Pediatrics. 10:23125. http://dx.doi.org/10:923125. 10.3389/fped.2022.923125
Brasil-Ministério da Saúde. (2019). Secretaria de Vigilância em Saúde, Coordenação- Geral de Desenvolvimento da Epidemiologia em Serviços. Guia de vigilância em saúde. (3a ed.).
Brasil- Ministério da Saúde. (2020). Meningite. https://www.gov.br/saude/pt-br/assuntos/saude-de-a-a-z/m/meningite-1
Bundy, L. M., & Noor, A. (2022). Neonatal Meningitis. In: Stat Pearls. Treasure Island (FL): StatPearls Publishing.
Cedeno-Burbano, A. A., Galeano-Trivino, G. A., Manquillo-Arias, W. A., & Muñoz-García, D. A. (2016). Salmonella enteritidis meningitis in an infant: Case report and literature review. Revista de la Facultad de Medicina. 64(3):575-580. https://doi.org/10.15446/revfacmed.v64n3.54613
Caldas, M. L. L. S., & Berezin, E. N. (2020). Epidemiology of meningitis in children in a Brazilian northeastern state. Research, Society and Development, 9(9): e570997553, https://doi.org/10.33448/rsd-v9i9.7553
Cardoso, L. C. C., Santos, M. K. A., & Mariano, N. F. (2019). Caracterização do perfil epidemiológico de meningite: estudo ecológico na Região Nordeste de 2008 a 2018 2º Congresso Internacional de Enfermagem - CIE/13° Jornada de Enfermagem da Unit (JEU).
Colman, V. P., & Reda, N. (2019). Aspectos epidemiológicos da meningite no município de Porto Nacional (TO), no período de 2014 a 2018. Scire Salutis. 9(2):49-59. http://doi.org/10.6008/CBPC2236-9600.2019.002.0006
Filho, A. M. R. C., & Moreira, A. S. S. (2019). Viral Etiology Meningitis and Encephalitis. Revista da Faculdade de Medicina de Teresópolis. 3(1): 85-95.
Gilbert, P. B., Isbrucker, R., Andrews, N., Goldblatt, D., Heath, P. T., Izu, A., Madhi, S. A., Moulton, L., Schrag, S. J., Shang, N., Siber, G., & Sobanjo-Ter Meulen, A. (2022). Methodology for a correlate of protection for group B Streptococcus: Report from the Bill & Melinda Gates Foundation workshop held on 10 and 11 February 2021. Vaccine. 40(32):4283-4291.: http://doi.org/10.1016/j.vaccine.2022.05.016.
Ghuneim, N., Dheir, M., & Ali, K. A. (2016). Epidemiology of Different Types of Meningitis Cases in Gaza Governorates, Occupied Palestinian Territory, December 2013- January 2014. Journal of Antivirals & Antiretrovirals. 8(1):26-34. . http://doi.org/10.4172/jaa.1000132
Guillen-Pinto, D., Málaga-Espinoza, B., Ye-Tay, J., Rospigliosi-López, M. L., Montenegro-Rivera, A., & Rivas, M. Neonatal meningitis: a multicenter study in Lima, Peru. Rev Peru Med Exp Salud Publica. 2020;37(2):210-9. https://doi.org/10.17843/rpmesp.2020.372.4772.
Iregbu, K. C., & Abdullahi, N. (2015). Profiles of acute bacterial meningitis isolates in children in National Hospital, Abuja. Nigerian Medical Journal. 56(4): 297-300.
Kavuncuoglu, S., Gursoy, S., Turel, O., Aldemir, E. Y., & Hosaf, E. (2013). Neonatal bacterial meningitis in Turkey: epidemiology, risk factors, and prognosis. Journal of Infection in DevelopingCcountries. 7:73–81.
Macedo, R. M., Noleto, D. C., & Castanheira. E. P. (2019). Perfil epidemiológico da meningite bacteriana nas diferentes regiões brasileiras. RESU – Revista Educação em Saúde. 7( 2):144-149
Magalhães, R. S., & Santos, M. S. (2018). Perfil epidemiológico da meningite bacteriana no Município de Vitória da Conquista-Bahia, no período de 2008 a 2015. Revista de Ciências Médicas e Biológicas, 17 (1), 33-39.
Nour, M., & Alaidarous, A. (2017). simultaneous detection of bacterial meningitis in suspected cases of meningitis in children using PCR Assay, in Taif, Saudi Arabia. Merit Research Journal of Medicine and Medical Sciences. 8(3):337-341.
Ouchenir, L., Renaud, C., Khan, S., Bitnun, A., Boisvert, A. A., & McDonald J. (2017) The epidemiology, management, and outcomes of bacterial meningitis in infants. Pediatrics. 140:e20170476. http://doi.org/ 10.1542/peds.2017-0476
Pérez, M. G., Escarrá, Bqcas, F., Blanco, A., Reijtman, V., Mastroianni, A., Ceinos, M. C., Pellegrino, P., Bologna, R., & Rosanova M. T. (2017). Epidemiologia de las meningitis bacterianas en niños en un hospital pediatrico: 2011 – 2016. Medicina Infantil. XXIV:320- 324.
Prober, C. G., & Dyner, L. L. (2011). Central nervous system infections. In: Kliegman RM, Stanton BF, St. Geme III JW, et al. editors. Nelson textbook of pediatrics, 19th.ed. Philadelphia: Saunders Elsevier; c2011.
Queiroz, R. M. R., & Feferbaum, M. (2022). Metodologia da pesquisa em direito. Saraiva
Signorati, M.& Signorati, A. (2021). Epidemiological characteristics of Meningitis in the 7th Regional Health Department of the State of Paraná, in the período 2010-2019. Research, Society and Development.. 10(9): e29710918145, 10.33448/rsd-v10i9.18145.
Silva, H. C. G., & Mezarobb, A. N. (2018). Meningite no Brasil em 2015: O panorama da atualidade. Arquivos Catarinenses de Medicina. 47(1):34-46 .
Sztajnbok, D. C. N. (2012) Meningite Bacteriana Aguda Revista de Pediatria SOPERJ. 13( 2):72-76.
van de Beek, D., Brouwer, M. C., Th,waites, G. E. & Tunkel, A. R. (2012). Advances in treatment of bacterial meningitis. Lancet. 380:1693–702. . http://doi.org/ 10.1016/S0140-6736(12)61186-6
van Kassel, M. N., Bijlsma, M. W., Brouwer, M. C., van der Ende, A., & van de Beek, D. (2019). Community-acquired group B streptococcal meningitis in adults: 33 cases from prospective cohort studies. Journal of Infection, 78: 54–57.
van Kassel, M. N., de Boer, S., Teeri, A. F., Jamrozy, D., Bentley, S. D., Brouwer, M. C., van der Ende, A. & van de Beek, D., & Bijlsma Me W. (2021) Molecular epidemiology and mortality of group B steptococcal meningitis and infant sepsis in the Netherlands: a 30-year nationwide surveillance study. Lancet Microbe. 2: e32–40. https://doi.org/10.1016/S26665247(20)30192-0
Ward, M. A., Greenwood, T. M., David, R., Kumar, B. S., Mazza, J. J., Steven, H., & Yale, M, D. (2010). Josef Brudzinski and Vladimir Mikhailovich Kernig: Signs for Diagnosing Meningitis. Clinical Medicine & Research. 8(1):13-17. https://doi.org/10.3121/cmr.2010.862
Xu, M., Hu, L., Huang, H., Wang, L., Tan, J., Zhang, Y., Chenm C., Zhang, X., & Huang, L. (2019). Etiology and Clinical Features of Full-Term Neonatal Bacterial Meningitis: A Multicenter Retrospective Cohort Study. Frontiers in Pediatrics. 7:31. https://doi.org/10.3389/fped.2019.00031.
Zunt, J. R., Kassebaum, N. J., Blake, N., Glennie, L., Wright, C., & Nichols, E. (2018). Global, regional, and national burden of meningitis, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurology. 17(12):1061–1082. https://doi.org/10.1016/S1474-4422(18)30387-9.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Nara Moraes Guimarães; Vitor Hugo Ramos Alves; Barbara Santarém Soares; Leonardo Murilha Ruiz; Leticia Cabral Guimarães; Vitor Marchito Soares; Dora Inés Kozusny-Andreani
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
