The use of Botulinum Toxin type A in the treatment of sialorrhea in the Intensive Care Unit: An integrative review
DOI:
https://doi.org/10.33448/rsd-v11i16.37783Keywords:
Botulinum Toxin Type A; Sialorrhea; Intensive Care Unit.Abstract
This integrative review aims to analyze scientific articles that relate the use of botulinum toxin type A in the treatment of sialorrhea in patients in Intensive Care Units. For this study, the descriptors were used: Botulinum Toxins Type A; Botulinum Toxins; Muscular Dystrophies; Muscular Dystrophy; Diseases of the Autonomic Nervous System; Intensive treatment unit; Intensive Care Units. The databases accessed were: PUBMED and MEDLINE. The collection followed 5 stages. First, the theme related to the objectives; second according to determination of inclusion/exclusion criteria; third collection and stratification of information; fourth evaluation of methods; fifth interpretation of results, discussion and conclusion. Of these, 100 articles were identified, those that did not meet the eligibility criteria were excluded and only 10 articles were selected for the study. The delimitation of the research clipping began in 2016, until the end of 2022. The use of botulinum toxin type A in the treatment of sialorrhea in the ICU, respects comparative criteria between objective, thematic associations and conclusions; according to the sequence: Authors/year/study design, objectives/correlations and associations/conclusions. In conclusion, TXB type A may be a bedside therapy option in patients with sialorrhea. TXB type A is effective and has rare side effects, improving the clinical status of patients. This review reveals the need for further experimental studies to justify the use of type A TXB in the protocol treatment of sialorrhea in patients with various neuromuscular diseases in the Intensive Care Unit.
References
Barbas, C. S. V. et al. (2014). Brazilian recommendations of mechanical ventilation 2013. Part I. Revista Brasileira de Terapia Intensiva. 26(2).
Cavichiolo, J. B. (2017). Avaliação clínica e laringoscópica de crianças com paralisia cerebral em uso de toxina botulínica tipo A intraparotídea. Retrieved from http://acervodigital.ufpr.br.
Colhado, O. C. G. et al. (2009). Toxina botulínica no tratamento da dor. Revista Brasileira de Anestesiologia, 59, 366-381.
Corso, B. L. et al. (2011). Abordagem terapêutica na sialorréia em paralisia cerebral: revisão sistemática. Med Reabil, São Paulo, 30(1), 913.
Costa, C. S. P. (2020). Avaliação da deglutição: intervenção do enfermeiro de reabilitação. MS thesis. Retrieved from http://repositorio.ipvc.pt
Dias, B. L. S., Fernandes, A. R. & Maia Filho, H. S. (2016). Sialorrhea in children with cerebral palsy. Jornal de Pediatria. 92(6), 549–58.
Gubbay, A. & Blackmore M. A. (2019). Effects of salivary gland botulinum Toxin-A on drooling and respiratory morbidity in children with neurological dysfunction. International Journal of Pediatric Otorhinolaryngology, 124, 124–128.
Jost, W. H. et al. (2020). Long-term incobotulinum toxin A treatment for chronic sialorrhea: Efficacy and safety over 64 weeks. Parkinsonism & Related Disorders, 70, 23–30.
Melo, K. S. et al. (2020). Uso da Toxina Botulínica no Tratamento em Crianças com Paralisia Cerebral/Use of Botulinic Toxin in the Treatment of Children with Cerebral Paralysis. ID on line Revista de Psicologia 14.51: 537-541.
Mendes, K. D. S. et al. (2008). Revisão integrativa: Método de Pesquisa para a incorporação de evidências na saúde e na enfermagem. Texto & contexto- enfermagem, 17(4), 758-64.
Nadel, S. et al. (2017). Ultrasound guided botulinum toxin injections into salivary glands: minimal invasive and safe treatment for drooling. International Journal of Oral and Maxillofacial Surgery, 46, 246.
Oliveira, A. F. et al. (2016). Application of botulinum toxin to treat sialorrhea in amyotrophic lateral sclerosis patients: a literature review. Einstein (São Paulo), 14(3), 431–434.
Oliveira, M. R. et al. (2009). O uso da bandagem elástica Kinesio no controle da sialorréia em crianças com paralisia cerebral. Acta Fisiátrica 16(4), 168-172.
Paroni, R. A. et al. (2016). Evidências de revisões sistemáticas Cochrane sobre uso da toxina botulínica. Revista Diagnóstico e Tratamento, 21(4023), 36.
Ribeiro, L. B. et al. (2019). Qualitative and quantitative scintigraphy in sialorrhea before and after botulinum toxin injection. The Laryngoscope, 129(11), 2521–2526.
Ruiz-Roca, J. A. et al. (2019). Effectiveness of the Botulinum Toxin for Treating Sialorrhea in Patients with Parkinson’s Disease: A Systematic Review. Journal of Clinical Medicine, 8(3), 317.
Silva, A. R. E. et al. (2019). "Uso da toxina botulínica tipo A como alternativa no controle da sialorreia: revisão de literatura.". Retrieved from http://131.0.244.66:8082/jspui/handle/123456789/1638
Singh, H. et al (2020). Efficacy of Botulinum Toxin for Treating Sialorrhea in Neuromuscular Conditions. Frontiers in Neurology, 11.
Sposito, M. M. & Teixeira, S. A. F. (2013). Toxina botulínica tipo A para o tratamento da sialorréia: revisão sistemática. Acta fisiátrica 20(3), 147-151.
Taib, B. G. et al (2019). Treatment of sialorrhoea with repeated ultrasound-guided injections of botulinum toxin A into the parotid and submandibular glands. British Journal of Oral and Maxillofacial Surgery, 57(5), 442–448.
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Copyright (c) 2022 Giovanna Calabrese Valentim; Renata Fialho Vieira; Fernando Martins Baeder ; Gabriela Traldi Zaffalon; Ana Carolina Lyra de Albuquerque ; Daniel Furtado Silva ; Keller de Martini ; Paola Fernanda Leal Corazza
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