Zinc-elicited stress tolerance in fungi
DOI:
https://doi.org/10.33448/rsd-v12i2.40044Keywords:
Zinc Sulfate; Fungi; Stress Tolerance; Toxicity.Abstract
Fungi for industrial and agricultural uses must endure a variety of physical and chemical challenges, collectively referred to as stresses. The fungal response to stress conditions may be due to impaired growth and metabolism. Understanding the physiology of stress responses can help alleviate the detrimental effects when the fungus is applied agricultural and industrial uses. The present study aims to review the physiological and morphological effects of zinc ions on fungi. Zinc is essential for the activity of zinc metalloenzymes, such as alcohol dehydrogenase and aldehyde dehydrogenase. It can activate riboflavin synthesis and increase protein content in fermenting yeast. However, excess zinc is toxic to the cell, and the cellular level must be finely controlled within an adequate range between 0.1 and 0.5 mM. In conclusion, a relationship between zinc and yeasts is observed but has not yet been fully defined in the fermentation process. Thus, studies are still needed to evaluate the physiological and morphological effects of zinc ions in fungi used in agriculture, such as tolerance of conidia produced in culture media with zinc or to conditions of oxidative stress, osmotic stress, ultraviolet radiation, and heat.
References
Böhm, S., Frishman, D., & Mewes, H. W. (1997). Variations of the C2H2 zinc finger motif in the yeast genome and classification of yeast zinc finger proteins. Nucleic Acids Research 25, 2464-2469. 10.1093/nar/25.12.2464.
Chandrasena, G., Walker, G. M., & Staines, H. J. (1997). Use of response surfaces to investigate metal ion interactions in yeast fermentations. Journal of the American Society of Brewing Chemists 55, 24-29. 10.1094/asbcj-55-0024.
De Nicola, R., Hazelwood, L. A., De Hulster, E. A. F., Walsh, M. C., Knijnenburg, T. A., Reinders, M. J. T., Walker, G. M., Pronk, J. T., Daran, J. -M., & Daran-Lapujade, P. (2007). Physiological and transcriptional responses of Saccharomyces cerevisiae to zinc limitation in chemostat cultures. Appl Environ Microb 73, 7680-7692. doi:10.1128/AEM.01445-07.
De Nicola, R., & Walker, G. M. (2008). Interaction between yeasts and zinc, in: Satyanarayana, T., Kuntze, G. (Eds.), Yeast Biotechnology: Diversity and Applications. Springer Science & Business Media BV, Dordecht, pp. 237-257.
Jones, R. P., & Gadd, G. M. (1990). Ionic nutrition of yeast—physiological mechanisms involved and implications for biotechnology. Enzyme Microb Tech 12, 402-418. https://doi.org/10.1016/0141-0229(90)90051-Q.
Kreder, G. C. (1999). Yeast assimilation of Trub-Bound Zinc. Journal of the American Society of Brewing Chemists 57, 129-132. 10.1094/asbcj-57-0129.
Obata, H., Hayashi, A., Toda, T., & Umebayashi, M. (1996). Effects of zinc deficiency on the growth, proteins, and other constituents of yeast, Saccharomyces cerevisiae, cells. Soil Science and Plant Nutrition 42, 147-154. 10.1080/00380768.1996.10414698.
Rangel, D. E .N. (2011). Stress induced cross-protection against environmental challenges on prokaryotic and eukaryotic microbes. World J. Microbiol. Biotechnol. 27, 1281-1296. 10.1007/s11274-010-0584-3.
Rangel, D. E .N., Alder-Rangel, A., Dadachova, E., Finlay, R. D., Kupiec, M., Dijksterhuis, J., Braga, G. U. L., Corrochano, L. M., & Hallsworth, J. E. (2015a). Fungal stress biology: a preface to the Fungal Stress Responses special edition. Curr. Gen. 61, 231-238. 10.1007/s00294-015-0500-3.
Rangel, D. E. N., Braga, G. U .L., Fernandes, É. K. K., Keyser, C. A., Hallsworth, J .E., & Roberts, D. W. (2015b). Stress tolerance and virulence of insect-pathogenic fungi are determined by environmental conditions during conidial formation. Curr. Gen. 61, 383-404. 10.1007/s00294-015-0477-y.
Rangel, D. E. N., Finlay, R.D ., Hallsworth, J. E., Dadachova, E., & Gadd, G. M. (2018). Fungal strategies for dealing with environmental and agricultural stress. Fungal Biol. 122, 602-612. 10.1016/j.funbio.2018.02.002.
Tosun, A., & Ergun, M. (2007). Use of experimental design method to investigate metal ion effects in yeast fermentations. Journal of Chemical Technology & Biotechnology 82, 11-15. https://doi.org/10.1002/jctb.1616.
Vallee, B. L., & Auld, D. S. (1990). Zinc coordination, function, and structure of zinc enzymes and other proteins. Biochemistry 29, 5647-5659. 10.1021/bi00476a001.
Walker, G. M. (2004). Metals in Yeast Fermentation Processes, Advances in Applied Microbiology. Academic Press, pp. 197-229.
Walker, G. M., & Basso, T. O. (2019). Mitigating stress in industrial yeasts. Fungal Biol. https://doi.org/10.1016/j.funbio.2019.10.010.
Walker, G. M., & Birch, R. M. (1999). Environmental stress responses in industrial yeasts, 5th Aviemore Conference on Malting, Brewing & Distilling. Campbell Institute of Brewing, London, pp. 195-197.
Zhao, H., & Eide, D. (1996). The yeast ZRT1 gene encodes the zinc transporter protein of a high-affinity uptake system induced by zinc limitation. Proceedings of the National Academy of Sciences 93, 2454-2458. doi:10.1073/pnas.93.6.2454.
Zhao, X. Q., & Bai, F. W., (2012). Zinc and yeast stress tolerance: Micronutrient plays a big role. J Biotechnol 158, 176-183. https://doi.org/10.1016/j.jbiotec.2011.06.038.
Zhao, X. Q., & Bai, F. W. (2009). Mechanisms of yeast stress tolerance and its manipulation for efficient fuel ethanol production. J Biotechnol 144, 23-30. S0168-1656(09)00205-3 [pii]10.1016/j.jbiotec.2009.05.001.
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