Survival of patients with malignant neoplastic wound served at a Cancer Center
DOI:
https://doi.org/10.33448/rsd-v12i9.43280Keywords:
Oncology; Neoplasms; Survival analysis; Wounds and injuries; Palliative care.Abstract
Objective: To evaluate the survival of patients with malignant neoplastic wound treated at a Cancer Center. Method: This is an observational, retrospective and descriptive cohort study, with a quantitative approach, using secondary data extracted from medical records of patients diagnosed with cancer who had a malignant neoplastic wound. Data collection was carried out between 2018 and 2020. For the analysis of quantitative variables, absolute and relative frequencies were considered. To determine the probability of survival, the Kaplan-Meier estimator was used. The log-rank test was used to determine the existence of differences between the survival curves. Results and discussion: The sample consisted of 118 patients. Among the participants, the majority were women, white, married, aged over 60 years, who had completed higher education, attended by the health insurance. There was a predominance of patients diagnosed with breast and head and neck cancer, with advanced staging. The mean overall survival of the sample was 10 months. The probability of overall survival at 1 year was 20%, and at 2 years it was 9%. Smoking history was statistically significant (p=0.05), showing that participants who never smoked had a longer overall survival. The treatment scheme was statistically significant (p=0.005), showing that participants who received the combination of radiotherapy and chemotherapy had a longer survival. Conclusion: The overall survival of patients with a malignant neoplastic wound was eight months, with worse results for patients with a history of smoking and better results for combined treatments.
References
Agra, G., Medeiros, M. V. D. S., Brito, D. T. F. de, Pimentel, E. R. S., Formiga, N. S., & Costa, M. M. L. (2019). Knowledge and practice of nurses in the control of pain in patients with malignant wounds. Enfermagem Brasil, 18(1): 3–11. https://doi.org/10.33233/eb.v18i1.1039
Alexander, S.J. (2010). An intense and unforgettable experience: the lived experience of malignant wounds from the perspectives of patients, caregivers and nurses. International Journal of Wound care, 7(6): 456-65
Batista, G.B., Moreira J.A., Leite A. L., & Moreira C. I. H. (2020). Breast cancer: risk factors and prevention methods. Research, Society and Development, 12(9): e15191211077. http://dx.doi.org/10.33448/rsd-v9i12.11077
Brasil (2014). Ministério da Saúde. Secretaria de Atenção à Saúde. Protocolos clínicos e diretrizes terapêuticas em Oncologia. Brasília: Ministério da Saúde. https://bvsms.saude.gov.br/bvs/publicacoes/protocolos_clinicos_diretrizes_terapeuticas_oncologia.pdf
Cardoso, M.S., Baeza F.L.C., & Castan J.U. (2021). Determinantes sociais de saúde e a análise do perfil de internações de uma unidade psiquiátrica do sul do Brasil. Revista Sociedade Brasileira de Psicologia Hospitalar, 24(2): 142–150. https://doi.org/10.57167/Rev-SBPH.24.89
Faria, R.P., Fuly, P.S.C., Santos, M.L.S.C., Camacho, A.C.L.F., Moraes, E.B., Braga, K.V.A. (2022). Conhecimento do enfermeiro sobre ferida tumoral: uma revisão de escopo. Research, Society and Development, 11(6): e57911629546. http://dx.doi.org/10.33448/rsd-v11i6.29546
Gibson, S., & Green, J. (2013). Review of patients' experiences with fungating wounds and associated quality of life. Journal of wound care, 22(5): 265-275
Hochman , B., Nahas F. X., Oliveira, Filho R. S., & Ferreira , L. M. (2005). Desenhos de pesquisa. Acta Cir Bras20 Suppl.2:02-9 http://www.scielo.br/acb
Instituto Nacional de Câncer José Alencar Gomes da Silva. (2023). Incidência de câncer no Brasil / Instituto Nacional de Câncer José Alencar Gomes da Silva. – Rio de Janeiro: INCA, 2022. https://www.inca.gov.br/sites/ufu.sti.inca.local/files/media/document/estimativa-2023.pdf
Instituto Nacional de Câncer José Alencar Gomes da Silva. (2009). Tratamento e controle de feridas tumorais e úlceras por pressão no câncer avançado. INCA, Rio de Janeiro. http://bvsms.saude.gov.br/bvs/publicacoes/inca/Feridas_Tumorais.pdf
Kranzfelder, M., Schuster, T., Geinitz, H., Friess, H., & Buchler P. (2011). Meta-analysis of neoadjuvant treatment modalities and definitive non-surgical therapy for oesophageal squamous cell cancer. Br J Surg, 98(6):768-83
Lisboa, I. N. D., & Valença, M. P. (2016). Caracterização de pacientes com feridas neoplásicas. Estima, 14(1): 21–28. https://doi.org/10.5327/z1806-3144201600010004
Lo S., Hayter M., Hu W., Tai C., Hsu M., & Li, Y F. (2012). Symptom burden and quality of life in patients with malignant fungating wounds. Journal of advanced nursing, 68(6): 1312–1321
Ministério da Saúde. (2022). Diretrizes Diagnósticas e Terapêuticas – Melanoma Cutâneo. https://www.gov.br/conitec/pt-br/midias/consultas/relatorios/2022/20220516_ddt_melanoma_-pos-conitec.pdf
Moreira, S.C., Rocha, L.M., Espírito Santo L.D., Moreira L. M. A. (2013). Associação entre a suscetibilidade à exposição solar e a ocorrência de câncer de pele em albinos. Revista Ciências Médicas e Biológicas, 12(1):70-74
Morrison, J., Haldar, K., Kehoe, S., & Lawrie TA. (2007). Chemotherapy versus surgery for initial treatment in advanced. Cochrane Database Syst Ver, (4):CD005343. doi: 10.1002/14651858
Nogueira, W. P., Agra G., Formiga N. S., & Costa M. M. L. (2017). Perfil sociodemográfico, clínico e terapêutico de pacientes com feridas neoplásicas. Revista Enfermagem UFPE on-line, 11(8):3039-49
Oliveira, M. I. A., Silva R. A. L., Abrel A.M., Freitas V. L., & Roehrs H. (2022). Cuidados de enfermagem à ferida oncológica: conhecimento de enfermeiros residentes. Research, Society and Development. 11(5); e54111528477. http://dx.doi.org/10.33448/rsd-v11i5.28477
Probst, S., Arber, A., & Faithfull, S. (2013). Malignant fungating wounds: the meaning of living in an unbounded body. European journal of oncology nursing : the official journal of European Oncology Nursing Society, 17(1): 38–45
Santos, A. S. O., Mesquita, A. C., Silva, A. M. C. R., Paiva, F. M. S. N., Nascimento, C. T., & Peres, L. M. V. (2022). Aspectos fisiopatologicos das feridas neoplasicas: revisão de escopo. Research, Society and Development,11(3), e58711326832
Santos, M. O, Lima F. C. S., Martins L. F. L., Oliveira J. F. P., Almeida L. M., & Cancela M. C. (2023). Estimativa de Incidência de Câncer no Brasil, 2023-2025. Revista Brasileira de Cancerologia, 69(1): e-213700 https://rbc.inca.gov.br/index.php/revista/article/view/3700/2644
Santos, W. A., Fuly, P. S. C., Souto, M. D., Santos, M. L. S. C., & Beretta, L. L. (2019). Association between odor and social isolation in patients with malignant tumor wounds: pilot study. Enfermería Global, 18(53): 19-65
Schmidt, F. M. Q., Firmino, F., Lenza, N. de F. B., & Santos, V. L. C. de G. (2020). Nursing team knowledge on care for patients with fungating wounds. Revista Brasileira de Enfermagem, 73. https://doi.org/10.1590/0034-7167-2017-0738
Silva, K. R. M. da, Bontempo, P. de S. M., Reis, P. E. D. dos, Vasques, C. I., Gomes, I. P., & Simino, G. P. R. (2015). Intervenções terapêuticas em feridas tumorais: relato de casos. Revista Brasileira de Cancerologia, 61(4): 373-379
Silva, F. A., Roussenq S. C., Tavares, M. G. S., Souza C. P. F., Mozzini C. B., Benetti M., & Dias M. (2020). Perfil Epidemiológico dos Pacientes com Câncer de Cabeça e Pescoço em um Centro Oncológico no Sul do Brasil. Revista Brasileira de Cancerologia; 66(1): e-08455
Soares, R. de S., Cunha, D. A. de O. da, & Fuly, P. dos S. C. (2019). Cuidados de enfermagem com feridas neoplásicas. Revista de Enfermagem UFPE, 13(1): 3456-3463
Souza, M. A. O., Souza, N. R., Melo, J. T. S., Xavier, M. A. C. A., Almeida, G. L., & Santos, I. C. R. V. (2018) Escalas de avaliação de odor em feridas neoplásicas: uma revisão integrativa. Revista Brasileira de Enfermagem, 71(5):2552-60. doi: https://doi.org/10.1590/0034-7167-2017-0428
Tilley, C., Lipson, J., & Ramos, M. (2016). Palliative wound care for malignant fungating wounds: holistic considerations at enf-of-life. Nurs Clin N Am; 51(3):513-31
Wild, C. P., Weiderpass, E., & Stewart, B. W. (2020). World cancer report: cancer research for cancer prevention. Lyon, France: International Agency for Research on Cancer, https://www.iccp-portal.org/system/files/resources/IARC%20World%20Cancer%20Report%202020.pdf
Wong, R. K., & Malthaner, R. (2010). Combined chemotherapy and radiotherapy (without surgery) compared with radiotherapy alone in localized carcinoma of the esophagus. Cochrane Database of Systematic Reviews. In: The Cochrane Library; (2)
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