Changes in hemorrhagic diseases resulting from a deficit in one or more clotting factors: Review article
DOI:
https://doi.org/10.33448/rsd-v12i14.44483Keywords:
Hemophilia; Diagnosis; Therapeutic behaviors; Epidemiology.Abstract
Hemophilia is an alteration related to genes, hemorrhagic, and of recessive inheritance, affecting only male members, resulting from modifications in the fundamental units of heredity, encoding factors VIII (hemophilia A) or IX (hemophilia B) of coagulation, located on the long arm of the X chromosome contained in blood plasma responsible for the complex sequence of chemical reactions that result in the formation of a fibrin clot. The objective of the inquiry was to argue the vast reference that deals with the presence of hemophilia in the face of the diagnostic, laboratory, therapeutic and outpatient approach. This is a narrative review composed of 21 articles, using the descriptors "Hemophilia" and "Treatment". It is concluded that Hemophilia type A and B is a disease that has been extensively investigated over time, however it involves numerous highly complex contextualizations that need to be considered and the laboratory analyzes used for the investigation and monitoring of hemophilia, promote conjectures limited, given the complications of quantifying low levels of antibodies.
References
ABRAPHEM. (2019). Associação Brasileira de Pessoas Com Hemofilia. Associação Brasileira de Pessoas Com Hemofilia (ABRAPHEM)
Bezerra, G., et al. (2020). Atuação Clínica do Farmacêutico no Tratamento de Hemofilia. In: Anais da Jornada Acadêmica Integrada: JAI. Guarabira (PB), EESAP.
Bezerra, J. R. P., et al. (2022). Relação entre adesão ao tratamento e qualidade de vida na hemofilia: revisão integrativa da literatura. Research, Society and Development. 11(11), e448111130318.
Braga, H. A. C. C. (2022). Hemofilia: uma revisão de literatura. [Monografia] (Graduação em Biomedicina), Centro de Biociências. Universidade Federal do Rio Grande do Norte, Natal.
BRASIL. (2015). Manual de Hemofilia [Manual]. Ministério da Saúde, Secretaria de Atenção à Saúde. Departamento de Atenção Especializada e Temática. 2.
Brasil. (2021). Ministério da Saúde. Protocolo de uso de Emicizumabe por pacientes com Hemofilia A e inibidores do Fator VIII refratários ao tratamento de imunotolerância. Ministério da Saúde, Secretaria de Atenção à Saúde. Departamento de Atenção Especializada e Temática.
Cavalcante, B. F., et al. (2020). Diagnóstico tardio de hemofilia tipo a em paciente politraumatizado: um relato de caso. Revista de Patologia do Tocantins. 7(2), 22-25.
Feijo, A. M., Schwartz, E., Santos, B. P., & Lise, F. (2021). Adaptando para (con)viver: experiência de homens com a hemofilia no sul do Brasil. Rev Gaúcha Enferm. 2(3).
Kempton, C. L., & Payne, A. B. (2018). HLA-DRB1–factor VIII binding is a risk factor for inhibitor development in nonsevere hemophilia: a case-control study. Blood Advances. 2(14), 1750-1755.
Kim, H. Y., et al. (2018). Ethnicity-specific impact of HLA I/II genotypes on the risk of inhibitor development: data from Korean patients with severe hemophilia A. Annals of Hematology. 97(9), 1695-1700.
Ljung, R. C. (2018). How I manage patients with inherited haemophilia A and B and factor inhibitors. British Journal of Haematology. 180(4), 501-510.
Oliveira, A. B. T., et al. (2022). Hemofilia: Fisiopatologia e Diagnóstico. Research, Society and Development. v. 11, n. 12, p. e564111234935-e564111234935.
Oliveira, A. B. T., et al. (2022). Hemofilia: Fisiopatologia e Diagnóstico. Research, Society and Development. 11(12), e564111234935.
Santos, I. B., et al. (2021). Aspectos clínicos e psicossociais na perspectiva de portadores da hemofilia: uma análise sobre o processo saúde-doença e qualidade de vida. Research, Society and Development. 10(12), e566101220885.
Santos, M. A., et al. (2020). Reflexões sobre o bullying com hemofílicos nas escolas. Research, Society and Development. 9(8), e377985476.
Santos, M. R., et al. (2022). Perquirição clínica e epidemiológica do tratamento de pacientes com aloaticorpos inibidores em hemofilia do tipo A atendidos em um hemocentro no nordeste brasileiro. Research, Society and Development. 1(4), e26711427435-e26711427435.
Santos, M. R., et al. (2022). Perquirição clínica e epidemiológica do tratamento de pacientes com aloaticorpos inibidores em hemofilia do tipo A atendidos em um hemocentro no nordeste brasileiro. Research, Society and Development. 11(4), e26711427435.
Sayago, M., & Lorenzo, C. (2020). O acesso global e nacional ao tratamento da hemofilia: reflexões da bioética crítica sobre exclusão em saúde. Interface (Botucatu). 24(2), e180722.
Silva, A. M. G., et al. (2022). Impacto da hemofilia nas atividades escolares, laborais e de lazer de pacientes atendidos no Hemocentro Regional de Montes Claros/Minas Gerais. Research, Society and Development 11(13), e36011133566.
Silveira Ribeiro, J. P. Q., et al. (2021). Aspectos genéticos da hemofilia a Revisão de literatura. Brazilian Journal of Development. 7(5), 48349-48362.
Silvério, A. A. G., et al. (2022). Impacto do desenvolvimento de inibidores no tratamento e qualidade de vida de pacientes com hemofilia: uma revisão de literatura. Research, Society and Development. 11(13), e359111335638.
Srivastava, A., et al. (2013) Guidelines for the management of hemophilia. Haemophilia, Osney Mead. 19(1), e1-47.
Teles, W. S., et al. (2021). Terapêutica das coagulopatias em pacientes atendidos no hemocentro de uma região do nordeste brasileiro. Research, Society and Development. 10(9), e15510917813.
Torres, O. A., et al. (2019). Coping strategies in young and adult haemophilia patients: a tool for the adaptation to the disease. Haemophilia. 25(3), 392-7.
Valadares, A. J. E., et al. (2021). Estudo de caso clínico de hemofilia tipo b–estudo de caso clínico multidisciplinar no serviço estadual de reabilitação em Araguaína-TO. Facit Business and Technology Journal. 2(31).
World Federation of Hemophilia. (2021). Annual global survey 2021. (wfh.org).
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Ádamo Newton Marinho Andrade; Mariamália Newton Andrade; Weber de Santana Teles; Max Cruz da Silva
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
