Mortality trend of cholecystitis in the brazilian Northeast, from 2013 to 2022

Authors

DOI:

https://doi.org/10.33448/rsd-v13i3.45189

Keywords:

Cholelithiasis; Cholecystitis; Mortality; Epidemiology.

Abstract

Cholelithiasis commonly remains asymptomatic, although the obstruction of the cystic duct can occur, generating symptoms. The objective of the study was to understand the epidemiological profile of individuals who died from cholecystitis in the Northeast region, from 2013 to 2022, and to comprehend the associated aspects of this mortality. This is an epidemiological, observational, descriptive study, with a quantitative approach, utilizing data from the Department of Information of the Unified Health System (DATASUS) via the Mortality Information System (SIM). The investigated variables included the number of deaths, mortality rate, gender, age group, race/ethnicity, marital status, and education level. The study identified a total of 3,847 deaths due to cholecystitis in the Northeast region, with a growing trend during the study period. The state of Bahia had the highest percentage (20.9%), and states with lower Human Development Index (HDI) exhibited lower mortality rates. Females predominated with 61.3%, and there was a prevalence of deaths in older age groups (62.8% for ages 70 to 79 and 80 years or older). Individuals of mixed race and white ethnicity accounted for 86.23% of the deaths, and married and widowed marital statuses also showed the highest values (61.27%). The analyzed data contribute to healthcare intervention, as access to information determines disease patterns in society, enabling the development of targeted and effective public policies.

References

Aguiar, R. G. P., Souza Júnior, F. E. A., Rocha Júnior, J. L. G., Pessoa, F. S. R. P., Silva, L. P., & Carmo, G. C. (2022). Clinical and epidemiological evaluation of complications associated with gallstones in a tertiary hospital. Arquivos de Gastroenterologia, 59(3), 352-357. https://doi.org/10.1590/S0004-2803.202203000-64

Amorim, K. P. C. (2019). Ética em pesquisa no sistema CEP-CONEP brasileiro: reflexões necessárias. Ciência & Saúde Coletiva, 24(3), 1033-1040. https://doi.org/10.1590/1413-81232018243.35292016

Araújo, G. M., Oliveira, L. S. A. de., Bastos, L. M. G., Assis, R. R., & Mariosa, N. D. F. (2022). Epidemiological profile of patients submitted to cholecystectomy in a hospital of southwest goiano. Research, Society and Development, 11(4), e14211426991. https://doi.org/10.33448/rsd-v11i4.26991

Balaj, M., Henson, C. A., Aronsson, A., Aravkin, A., Beck, K., Degail, C., Donadello, L., Eikemo, K., Friedman, J., Giouleka, A., Gradeci, I., Hay, S. I., Jensen, M. R., Mclaughlin, S. A., Mullany, E. C., O’connell, E. M., Sripada, K., Stonkute, D., Sorensen, R. J. D., & Gakidou, E. (2024). Effects of education on adult mortality: a global systematic review and meta-analysis. The Lancet Public Health. https://doi.org/10.1016/s2468-2667(23)00306-7

Bekheit, M., Rajan, S., Wohlgemut, J. M., Watson, A. J. M., & Ramsay, G. (2023). Comprehensive assessment of the management of acute cholecystitis in Scotland: population-wide cohort study. BJS Open, 7(4). https://doi.org/10.1093/bjsopen/zrad073

Cianci, P., & Restini, E. (2021). Management of cholelithiasis with choledocholithiasis: Endoscopic and surgical approaches. World journal of gastroenterology, 27(28), 4536–4554. https://doi.org/10.3748/wjg.v27.i28.4536

Departamento de Informática do Sistema Único de Saúde (n. d.). CID-10. http://www2.datasus.gov.br/cid10/V2008/cid10.htm

Departamento de Informática do Sistema Único de Saúde (n. d.). Estatísticas vitais. Sistema de Informações sobre Mortalidade. https://datasus.saude.gov.br/mortalidade-desde-1996-pela-cid-10

Escartín, A., González, M., Muriel, P., Cuello, E., Pinillos, A., Santamaría, M., Salvador, H., & Olsina, J. J. (2021). Litiasic acute cholecystitis: application of Tokyo Guidelines in severity grading. Cirugia y cirujanos, 89(1), 12–21. https://doi.org/10.24875/CIRU.19001616

Feldman, I., Feldman, L., Shapiro, D. S., Munter, G., Yinnon, A. M., & Friedman, R. (2020). Characteristics and outcome of elderly patients admitted for acute cholecystitis to medical or surgical wards. Israel journal of health policy research, 9(1), 23. https://doi.org/10.1186/s13584-020-00383-4

Fernanda, R., Toassi, C., & Petry, P. (2021). Metodologia Científica aplicada à área da Saúde 2ª edição. Editora da UFRGS. https://lume.ufrgs.br/bitstream/handle/10183/218553/001123326.pdf?sequence=1&isAllowed=y

Galvão, A. L. M., Oliveira, E., Germani, A. C. C. G., & Luiz, O. do C. (2021). Determinantes estruturais da saúde, raça, gênero e classe social: uma revisão de escopo. Saúde e Sociedade, 30(2), e200743. https://doi.org/10.1590/S0104-12902021200743

González-Castillo, A. M., Sancho-Insenser, J., De Miguel-Palacio, M., Morera-Casaponsa, J.-R., Membrilla-Fernández, E., Pons-Fragero, M.-J., Pera-Román, M., & Grande-Posa, L. (2021). Mortality risk estimation in acute calculous cholecystitis: beyond the Tokyo Guidelines. World Journal of Emergency Surgery, 16(1). https://doi.org/10.1186/s13017-021-00368-x

Instituto Brasileiro de Geografia e Estatística (2010). Censo demográfico 2010. Nupcialidade. https://sidra.ibge.gov.br/tabela/3193#resultado

Instituto Brasileiro de Geografia e Estatística (2022). Censo demográfico 2022. Panorama do censo. https://censo2022.ibge.gov.br/panorama/

Instituto Brasileiro de Geografia e Estatística (2021). Índice de Desenvolvimento Humano. https://cidades.ibge.gov.br/brasil/pesquisa/37/30255

Irigonhê, A. T. D., Franzoni, A. A. B., Teixeira, H. W., Rezende, L. O., Klipp, M. U. S., Purim, K. S. M., Tsumanuma, F. K., & Chibata, M. (2020). Análise do perfil clínico epidemiológico dos pacientes submetidos a colecistectomia videolaparoscópica em um hospital de ensino de Curitiba. Revista do Colégio Brasileiro de Cirurgiões, 47. https://doi.org/10.1590/0100-6991e-20202388

Jones, M. W., Weir, C. B., & Ghassemzadeh, S. (2023) Gallstones (cholelithiasis). StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK459370/

Jones, M. W., Genova, R., & O’Rourke, M. C. (2023). Acute cholecystitis. StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK459171/

Jones, M. W., Gnanapandithan, K., Panneerselvam, D., & Ferguson., T. (2023). Chronic cholecystitis. StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK470236/#article-19521.s17

Kang, Q., Kang, G., Li, R., Zhu, X., Yu, Y., & Yu, Q. (2018). Relationship of gallbladder diseases with sociodemographic characteristics, lifestyle, and chronic diseases in northeastern China. International Journal of Environmental Research and Public Health, 15(11), 2596. https://doi.org/10.3390/ijerph15112596

Li, S., Guizzetti, L., Ma, C., Shaheen, A. A., Dixon, E., Ball, C., Wani, S., & Forbes, N. (2023). Epidemiology and outcomes of symptomatic cholelithiasis and cholecystitis in the USA: trends and urban–rural variations. Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract, 27(5), 932–944. https://doi.org/10.1007/s11605-023-05604-0

Lodha, M., Chauhan, A. S., Puranik, A., Meena, S. P., Badkur, M., Chaudhary, R., Chaudhary, I. S., Sairam, M. V., Kumar, V., & Lodha, R. (2022). Clinical profile and evaluation of outcomes of symptomatic gallstone disease in the senior citizen population. Cureus 14(8), e28492. https://doi.org/10.7759/cureus.28492

Malta, D. C., Bernal, R. T. I., Lima, M. G., Silva, A. G., Szwarcwald, C. L., & Barros, M. B. A. (2021). Socioeconomic inequalities related to noncommunicable diseases and their limitations: National Health Survey, 2019. Revista Brasileira de Epidemiologia, 24, e210011. https://doi.org/10.1590/1980-549720210011.supl.2

Mytton, J., Daliya, P., Singh, P., Parsons, S. L., Lobo, D. N., Lilford, R., & Vohra, R. S. (2021). Outcomes following an index emergency admission with cholecystitis: a national cohort study. Annals of Surgery. 274(2), 367-374. https://doi.org/10.1097/sla.0000000000003599

Nascimento, J. H. F. do, Tomaz, S. C., Souza-Filho, B. M. de, Vieira, A. T. S., Andrade, A. B. de, & Gusmão-Cunha, A. (2022). A population study on gender and ethnicity differences in gallbladder disease in Brazil. Arquivos Brasileiros de Cirurgia Digestiva, 35. https://doi.org/10.1590/0102-672020210002e1652

Nascimento, L. N. do, Ribeiro Neto, G., Silva, F. C. da, & Oliveira, S. C. V. de. (2023). Prevalência e fatores associados à mortalidade de pacientes submetidos a colecistectomia em um hospital público do Sul do Brasil no período de 2015 a 2020. Research, Society and Development, 12(1), e3112139221. https://doi.org/10.33448/rsd-v12i1.39221

Novacek, G. (2006). Gender and gallstone disease. Wiener Medizinische Wochenschrift (1946), 156(19–20), 527–533. https://doi.org/10.1007/s10354-006-0346-x

Okamoto, K., Suzuki, K., Takada, T., Strasberg, S. M., Asbun, H. J., Endo, I., Iwashita, Y., Hibi, T., Pitt, H. A., Umezawa, A., Asai, K., Han, H.-S., Hwang, T.-L., Mori, Y., Yoon, Y.-S., Huang, W. S.-W., Belli, G., Dervenis, C., Yokoe, M., & Yamamoto, M. (2018). Tokyo Guidelines 2018: flowchart for the management of acute cholecystitis. Journal of Hepato-Biliary-Pancreatic Sciences, 25(1), 55–72. https://doi.org/10.1002/jhbp.516

Puka, K., Buckley, C., Mulia, N., Lasserre, A. M., Rehm, J., & Probst, C. (2022). Educational attainment and lifestyle risk factors associated with all-cause mortality in the US. JAMA Health Forum, 3(4), e220401. https://doi.org/10.1001/jamahealthforum.2022.0401

Sigmon, D. F., Dayal, N., & Meseeha, M. (2023). Biliary colic. StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK430772/

Tanaja, J., Lopez, R. A., & Meer, J. M. (2023). Cholelithiasis. StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK470440/

Published

16/03/2024

How to Cite

SOUSA, L. G. M. de .; ARAÚJO, M. C. S.; ROSA, O. M. dos S. Mortality trend of cholecystitis in the brazilian Northeast, from 2013 to 2022. Research, Society and Development, [S. l.], v. 13, n. 3, p. e5613345189, 2024. DOI: 10.33448/rsd-v13i3.45189. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/45189. Acesso em: 21 nov. 2024.

Issue

Section

Health Sciences