Impact on the mental health of trans young people after hormonal transition therapy

Authors

DOI:

https://doi.org/10.33448/rsd-v13i3.45215

Keywords:

Transgender; Hormonal Therapy; Mental Health.

Abstract

Introduction: The transgender person does not identify with the biological sex designated at birth. This lack of identification ends up causing anxious, depressive episodes and suicidal ideations. In this context, hormone transition therapy makes it possible to obtain characteristics of the desired gender. Objectives: To understand the impacts of hormonal therapies on the mental health of trans young people, elucidating whether there is a post-transition benefit in this scenario. Methodology: This review considered 14 articles found in PUBMED and 6 found in Google Scholar from the descriptors (transgender); (hormonal therapy) and (mental health). Studies dating back more than 5 years; incomplete texts; languages other than English or Portuguese and articles that did not concomitantly contemplate mental health and transgender were excluded. Discussion/Results: The study population was transgender women and men between 9 and 25 years old. The analysis time was from 3 months to 5 years. Among the articles, 12 agreed that access to hormone therapy is associated with improvements in quality of life and reduction in depression rates and an article suggests that there was no clinically significant change in mood symptoms, given the limitation of the population in study. Some articles portrayed the need to expand access to hormone therapy. Conclusion: Hormone therapy was associated with better quality of life and decreased depression and anxiety symptoms, probably due to identification with acquired physical characteristics. However, it is necessary to track diseases before, during and after the hormonal transition.

Author Biography

Leonardo Azevedo Mobilia Alvares, Centro Universitário São Camilo

  • Médico Endocrinologista Titulado pela Sociedade Brasileira de Endocrinologia e Metabologia;
  • Doutor em Ciências Médicas - FMUSP.
  • Especialista em Educacão em Saúde;
  • Pós-graduado em Medicina Esportiva;
  • Membro da Endocrine Society:
  • Docente do Centro Universitário São Camilo;
  • Diretor da Clínica Escola Promove São Camilo

References

Achille, C., Taggart, T., Eaton, N. R., Osipoff, J., Tafuri, K., Lane, A., & Wilson, T. A. (2020). Longitudinal impact of gender-affirming endocrine intervention on the mental health and well-being of transgender youths: preliminary results. International Journal of Pediatric Endocrinology, 2020(1), 1-5.

Aldridge, Z., Patel, S., Guo, B., Nixon, E., Pierre Bouman, W., Witcomb, G. L., & Arcelus, J. (2021). Long‐term effect of gender‐affirming hormone treatment on depression and anxiety symptoms in transgender people: A prospective cohort study. Andrology, 9(6), 1808-1816.

Aldridge, Z., Thorne, N., Bouman, W. P., Witcomb, G. L., & Arcelus, J. (2023, January). A Longitudinal Study Exploring the Role of Mental Health Symptoms and Social Support Regarding Life Satisfaction 18 Months after Initiation of Gender-Affirming Hormone Treatment. In Healthcare (Vol. 11, No. 3, p. 379). MDPI.

Baker, K. E., Wilson, L. M., Sharma, R., Dukhanin, V., McArthur, K., & Robinson, K. A. (2021). Hormone therapy, mental health, and quality of life among transgender people: a systematic review. Journal of the Endocrine Society, 5(4), bvab011.

Cantu, A. L., Moyer, D. N., Connelly, K. J., & Holley, A. L. (2020). Changes in anxiety and depression from intake to first follow-up among transgender youth in a pediatric endocrinology clinic. Transgender Health, 5(3), 196-200.

Defreyne, J., & T’Sjoen, G. (2019). Transmasculine hormone therapy. Endocrinology and Metabolism Clinics, 48(2), 357-375.

Green, A. E., DeChants, J. P., Price, M. N., & Davis, C. K. (2022). Association of gender-affirming hormone therapy with depression, thoughts of suicide, and attempted suicide among transgender and nonbinary youth. Journal of adolescent health, 70(4), 643-649.

Hatzenbuehler, M. L., & Pachankis, J. E. (2016). Stigma and minority stress as social determinants of health among lesbian, gay, bisexual, and transgender youth: Research evidence and clinical implications. Pediatric Clinics, 63(6), 985-997.

Iwamoto, S. J., Defreyne, J., Rothman, M. S., Van Schuylenbergh, J., Van de Bruaene, L., Motmans, J., & T’Sjoen, G. (2019). Health considerations for transgender women and remaining unknowns: a narrative review. Therapeutic advances in endocrinology and metabolism, 10, 2042018819871166.

Kuper, L. E., Stewart, S., Preston, S., Lau, M., & Lopez, X. (2020). Body dissatisfaction and mental health outcomes of youth on gender-affirming hormone therapy. Pediatrics, 145(4).

Mendes, C. (2022). O que é uma revisão narrativa de literatura: exemplos e considerações da metodologia. https://www.youtube.com/watch?v=YlBWSVsxvRM.

Ministério dos Direitos Humanos e da Cidadania. (2018). OMS retira transexualidade da lista de doenças e distúrbios mentais. Portal gov.br. 22 jun 2018.

Ministério da Saúde. (2016). Cuidar bem da saúde de cada um faz bem para todos, faz bem para o Brasil. Biblioteca Virtual em Saúde do Ministério da Saúde.

Ministério da Saúde. (2015). Transexualidade e Transversalidade na Saúde. Biblioteca Virtual em Saúde do Ministério da Saúde.

Monteiro S, Brigeiro M, Barbosa RM. Transgender health and rights. Cad Saude Publica. 2019;35(4):e00047119. English, Portuguese, Spanish. doi: 10.1590/0102-311X00047119. PMID: 30994736.

Nguyen, H. B., Chavez, A. M., Lipner, E., Hantsoo, L., Kornfield, S. L., Davies, R. D., & Epperson, C. N. (2018). Gender-affirming hormone use in transgender individuals: impact on behavioral health and cognition. Current psychiatry reports, 20, 1-9.

Radix, A. (2019). Hormone therapy for transgender adults. Urologic Clinics, 46(4), 467-473.

Rother, E. T. (2007). Revisión sistemática X Revisión narrativa. Acta paulista de enfermagem, 20, v-vi.

Tordoff, D. M., Wanta, J. W., Collin, A., Stepney, C., Inwards-Breland, D. J., & Ahrens, K. (2022). Mental health outcomes in transgender and nonbinary youths receiving gender-affirming care. JAMA network open, 5(2), e220978-e220978.

T’Sjoen, G., Arcelus, J., Gooren, L., Klink, D. T., & Tangpricha, V. (2019). Endocrinology of transgender medicine. Endocrine Reviews, 40(1), 97-117.

Watt, S. O., Tskhay, K. O., & Rule, N. O. (2018). Masculine voices predict well-being in female-to-male transgender individuals. Archives of sexual behavior, 47, 963-972.

Winter S, Diamond M, Green J, Karasic D, Reed T, Whittle S, Wylie K. Transgender people: health at the margins of society. Lancet. 2016 Jul 23;388(10042):390-400.

Published

16/03/2024

How to Cite

GATTI, L. C. .; SERAFIM, V. F. .; MACEDO, J. B. da S. .; SILVA, A. C. L. da .; SPADONI, C. G. .; SANTOS, L. A. G. .; ALVARES, L. A. M. .; OYAMA, P. R. L.; SANTOS, L. M. dos. Impact on the mental health of trans young people after hormonal transition therapy . Research, Society and Development, [S. l.], v. 13, n. 3, p. e6013345215, 2024. DOI: 10.33448/rsd-v13i3.45215. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/45215. Acesso em: 22 dec. 2024.

Issue

Section

Health Sciences