Considerations regarding patients’ knowledge about antibiotics in Endodontics: A narrative review

Authors

DOI:

https://doi.org/10.33448/rsd-v13i9.46848

Keywords:

Endodontics; Irreversible pulpitis; Antibiotics; Periodontitis; Apical abscess; Infection; Inappropriate prescribing.

Abstract

Dental antimicrobial stewardship is important in international efforts to combat antibiotic resistance and is therefore valuable in implementing AMS strategies in dental practices and outpatient clinics. The development of antibiotic prescribing guidelines with a clear description of the indications and ease of use of the regimen is necessary. The objective of this article is to present considerations regarding the knowledge on the prescription of antibiotics in endodontics by means of a narrative review carried out from searches in PubMed and MedLine databases using the following descriptors: endodontia, irreversible pulpite, antibiotics, periodontitis, abscess apical, infection.Articles published in 2015 and between 2020 and 2024 written in English and Portuguese were included. The articles selected after reading their abstract and checking their adequacy were added to the content of this review. Based on the considerations regarding this present review, it is possible to conclude that there is a need for continuing education programs on the use of antibiotics, international guidelines on antibiotic prophylaxis, prescription errors, antibiotic prescription and better prescription adequacy, debilitated patients at risk of developing bacterial endocarditis, chronic diseases that require prophylactic prescription before or during treatment, excessive prescription of antibiotics in cases of pulpitis and other unnecessary indications and prescription of antibiotics only performed in conditions of generalized edema formation, among others.

References

Abraham, S. B., Abdulla, N., Himratul-Aznita, W. H., Awad, M., Samaranayake, L. P. & Ahmed, H. M. A. (2020). Antibiotic prescribing practices of dentists for endodontic infections; a cross-sectional study. PLoS One,15(12):e0244585.

Abuhassna, M. A., Aldajani, H. A., AlQahtani, K. W., Alzahrani, A. K., AlAwwad, D. A., Suliman, O., Rajeh, M. T., Ashraf, S. & Al-Maweri, S. A. (2022). Antibiotic Prescription During Endodontic Treatment: Knowledge and Practices of Dental Interns in Saudi Arabia. Adv Med Educ Pract, 13:1321-1328.

Ahmadi, H., Ebrahimi, A. & Ahmadi, F. (2021). Antibiotic Therapy in Dentistry. Int J Dent, 28;2021:6667624.

Alobaid, M. A., Alobaid, S. & Alshahrani, M. (2021). Comparison of the Views of the General Dental Practitioners and Dental Interns in Asir, Saudi Arabia on Antibiotic Prescription for Endodontic Therapy: A Cross-Sectional Study. Infect Drug Resist, 14:3001-3009.

Alzahrani, A. A. H., Alzahrani, M. S. A., Aldannish, B. H., Alghamdi, H. S., Albanghali, M. A. & Almalki, S. S. R. (2020). Inappropriate Dental Antibiotic Prescriptions: Potential Driver of the Antimicrobial Resistance in Albaha Region, Saudi Arabia. Risk Manag Healthc Policy, 13:175-182.

Arabpour, F., Kuzekanani, M., Walsh, L.J. & Mirzaei, M. (2023). Knowledge, Attitudes and Performance of Iranian Endodontists to Patients with Kidney Diseases. Eur Endod J, 8(1):90-95.

Arıcan, B., Çiftçioğlu, E., Işık, V. & Karagöz-Küçükay, I. (2021). Evaluation of the knowledge of final-year dental students on the use of antibiotics in endodontics in Turkey. Aust Endod J, 47(2):320-326.

Banerjee, K., Kakkar, A., Shamsi, K. A., Bansal, D., Mathur, P., Potode, N. M., Pagariya, P., Azher, S. P., Chaudhari, A., Mandal, R., Karadkhele, A. S., Markandeywar, N., Dharmadhikari, S., Khandhedia, C., Mane, A., Mehta, S. & Joglekar, S. (2024).

Effectiveness of Oral Cephalexin-Clavulanic Acid, Cefuroxime, and Amoxicillin-Clavulanic Acid in the Management of Dental Infections: A Real-World, Retrospective, Electronic Medical Record-Based Study in India. Drugs Real World Outcomes, 11(1):53-68.

Baudet, A., Kichenbrand, C., Pulcini, C., Descroix, V., Lesclous, P., Thilly, N., Clément, C. & Guillet, J. (2020). Antibiotic use and resistance: a nationwide questionnaire survey among French dentists. Eur J Clin Microbiol Infect Dis, 39(7):1295-1303.

Cavalcante, L .T .C. & Oliveira, A. A. S. (2020). Métodos de revisão bibliográfica nos estudos científicos. Psicol Rev. 26(1). https://DoiOrg/10.5752/p.1678-9563.2020v26n1p82-100.

D'Ambrosio, F., Di Spirito, F., Amato, A., Caggiano, M., Lo Giudice, R. & Martina, S. (2022). Attitudes towards Antibiotic Prescription and Antimicrobial Resistance Awareness among Italian Dentists: What Are the Milestones? Healthcare (Basel, 10(8):1585.

Deniz-Sungur, D., Aksel, H., Karaismailoglu, E. & Sayin, T. C. (2020). The prescribing of antibiotics for endodontic infections by dentists in Turkey: a comprehensive survey. Int Endod J, 53(12):1715-1727.

Dias, N. M., Moreno, J. O., Alves, F. R., Gonçalves, L. S. & Provenzano, J. C. (2022). Antibiotic indication in endodontics by Colombian dentists with different levels of training: a survey. Acta Odontol Latinoam, 31;35(3):198-205.

Domínguez-Domínguez, L., López-Marrufo-Medina, A., Cabanillas-Balsera, D., Jiménez-Sánchez, M. C., Areal-Quecuty, V., López-López, J., Segura-Egea, J. J. & Martin-González, J. (2021). Antibiotics Prescription by Spanish General Practitioners in Primary Dental Care. Antibiotics (Basel), 10(6):703.

Drobac, M., Otasevic, K., Ramic, B., Cvjeticanin, M., Stojanac, I. & Petrovic, L. (2021). Antibiotic Prescribing Practices in Endodontic Infections: A Survey of Dentists in Serbia. Antibiotics (Basel), 12;10(1):67.

Farkaš, M., I, vančić Jokić, N., Mavrinac, M. & Tambić Andrašević A. (2021). Antibiotic Prescribing Habits and Antimicrobial Resistance Awareness of Dental Practitioners in Primorsko-Goranska County, Croatia. Microb Drug Resist, 27(11):1482-1488.

Khalil, D., Baranto, G., Lund, B. & Hultin, M. (2022). Antibiotic utilization in emergency dental care in Stockholm 2016: a cross sectional study. Acta Odontol Scand, 80(7):547-553.

Kumar, N., Khare, V. V., Jamdade, A., Aggarwal A., Rathore N. S. & Yadav, S. (2022). Antibiotic Susceptibility of the Bacteria Causing Odontogenic Infections: An Observational Study. J Indian Acad Oral Med Radiol, 34(4):442-446.

Licata, F., Di Gennaro, G., Cautela, V., Nobile C. G. A. & Bianco, A. (2021). Endodontic Infections and the Extent of Antibiotic Overprescription among Italian Dental Practitioners. Antimicrob Agents Chemother, 17;65(10):e0091421.

López-Marrufo-Medina, A., Domínguez-Domínguez, L., Cabanillas-Balsera, D., Areal-Quecuty, V., Crespo-Gallardo, I., Jiménez-Sánchez, M. C., López-López, J., Segura-Egea, J .J. & Martin-Gonzalez, J. (2022). Antibiotics prescription habits of Spanish endodontists: Impact of the ESE awareness campaign and position statement. J Clin Exp Dent, 14(1):e48-e54.

Medeiros, J. M. F., Prokopowitsch, I. & Haddad, J. E. Tratamento das urgências em endodontia. In: Haddad Filho, M.S. (2015). Endodontia de Vanguarda: mais fácil, mais rápida e mais segura. Editora Napoleão Ltda, 512p. 434.

Medeiros, J. M. F. de ., Ferreira , G. de S. ., Lima, K. do C., Pedron, I. G. ., & Shitsuka, C. . (2022). Comparativo de dois protocolos de substâncias químicas auxiliares utilizados em endodontia em duas faculdades de odontologia (USP-São Paulo e UNICAMP-Piracicaba). E-Acadêmica, 3(3), e3833242. https://doi.org/10.52076/eacad-v3i3.242

Mende, A., Venskutonis, T. & Mackeviciute, M. (2020). Trends in Systemic Antibiotic Therapy of Endodontic Infections: a Survey among Dental Practitioners in Lithuania. J Oral Maxillofac Res, 31;11(1):e2.

Méndez-Millán, J. A., León-López, M., Martín-González, J., Saúco-Márquez, J .J., Cabanillas-Balsera, D. & Segura-Egea, J .J. (2024). Antibiotic Over-Prescription by Dentists in the Treatment of Apical Periodontitis: A Systematic Review and Meta-Analysis. Antibiotics (Basel), 22;13(4):289.

Nguyen, S., Ahmed, L., Villarosa, A., George, A. & Yaacoub, A. (2023). The use of antibiotics in acute oral health patients presenting at public dental clinics in the Western Sydney region. Fam Pract, 40(1):9-15.

Parirokh, M., Saffarzadeh, A., Nakhaei, N. & Abbott, P. (2023). The Outcome of Prescribing Antibiotics for the Management of Patients with Endodontic Infections. Eur Endod J, 8(3):194-200.

Paumier, T. M. (2024) Appropriate antibiotic use in dentistry: a review of the literature and clinical recommendations. Gen Dent, 72(1):27-33.

Ramanathan, S., Yan, C. H., Hubbard, C., Calip, G. S., Sharp, L. K., Evans, C .T., Rowan, S., McGregor, J. C., Gross, A. E., Hershow, R. C. & Suda, K. J. (2023). Changes in antibiotic prescribing by dentists in the United States, 2012-2019. Infect Control Hosp Epidemiol, 44(11):1725-1730.

Rother, E. T. (2007). Revisão sistemática x revisão narrativa. Acta Paul Enferm. 20(2). Htpps://Doi.Org/10.1590/s0103-21002007000200001

Santos, M., França, R. C., Medeiros, J. M. F. & Haddad Filho, M. S. (2021). Diagnóstico e tratamento dos processos infecciosos periapicaia assintomáticos com riscos de agudização In: Haddad Filho, M.S., Lemos, E.M. & colaboradores. (2021). Endodontia sob controle: controle da dor e dos riscos com técnica fácil, rápida e segura. 1 ed. Nova Odessa, SP: Napoleão, p.101-115.

Schneider-Smith, E. G., Suda, K .J., Lew, D., Rowan, S., Hanna, D., Bach, T., Shimpi, N., Foraker, R. E. & Durkin, M. J. (2023). How decisions are made: Antibiotic stewardship in dentistry. Infect Control Hosp Epidemiol, 44(11):1731-1736.

Shemesh, A., Batashvili, G., Shuster, A., Slutzky, H., Moshonov, J., Buchkovskii, O., Lvovsky, A., Azizi, H., Levin, A., Itzhak, J. B. & Solomonov, M. (2022). International questionnaire study on systemic antibiotics in endodontics. Part 1. Prescribing practices for endodontic diagnoses and clinical scenarios. Clin Oral Investig, 26(3):2921-2926.

Šimundić Munitić, M., Šutej, I., Ćaćić, N., Tadin, A., Balić, M., Bago, I. & Poklepović Peričić, T. (2021). Knowledge and attitudes of Croatian Dentists Regarding Antibiotic Prescription in Endodontics: A Cross-sectional Questionnaire-based Study. Acta Stomatol Croat, 55(4):346-358.

Sović, J., Šegović, S., Tomasić, I., Pavelić, B., Šutej, I. & Anić, I. (2020). Antibiotic Administration Along with Endodontic Therapy in the Republic of Croatia: a Pilot Study. Acta Stomatol Croat, 54(3):314-321.

Teoh, L., Thompson, W. & Suda, K. (2020). Antimicrobial stewardship in dental practice. J Am Dent Assoc, 151(8):589-595.

Vengidesh, R., Kadandale, S., Ramachandran, A., Srinivasan, S., Parthasarathy, R., Thanikachalam, Y. & Kumar, P. (2023). Antibiotic Prescription Patterns for Endodontic Procedures in India: A Knowledge, Attitude, and Practices (KAP) Survey. Cureus, 15(4):e37804.

Walsh, L.J ., Ford, P. J., McGuire, T., van Driel, M. & Hollingworth, S. A. (2021). Trends in Australian dental prescribing of antibiotics: 2005-2016. Aust Dent J, 66 Suppl 1:537-S41.

Published

26/09/2024

How to Cite

MEDEIROS, J. M. F. de .; OLIVEIRA, M. M. de; LIRA, P. L. de .; MOREIRA, R. S. de S. .; CORDESHI, T.; SHITSUKA, C. Considerations regarding patients’ knowledge about antibiotics in Endodontics: A narrative review. Research, Society and Development, [S. l.], v. 13, n. 9, p. e10213946848, 2024. DOI: 10.33448/rsd-v13i9.46848. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/46848. Acesso em: 27 sep. 2024.

Issue

Section

Health Sciences