Clinical-epidemiological profile of women undergoing oncological treatment for invasive ductal breast carcinoma
DOI:
https://doi.org/10.33448/rsd-v10i1.11836Keywords:
Breast neoplasms; Epidemiology; Oncology; Women's health.Abstract
The aim of this study was to describe the clinical-epidemiological profile of women undergoing oncological treatment for invasive ductal breast carcinoma. This is a cross-sectional, descriptive and quantitative study carried out by data collection from clinical records of women undergoing breast cancer treatment in a private oncology service, considering sociodemographic and clinical variables. 125 women who met the proposed inclusion criteria were identified. Most of the patients were from Sergipe (71,2%), black or mixed (65,6%), with a partner (56%) and with a mean age of 53,5±11,4 years. Of these, 80,8% had no higher education and 77,6% had family income between one and three minimum wages. All patients underwent chemotherapy, 64,8% radical mastectomy and 36% radiotherapy. In addition, 32,8% showed changes in self-image, 24,8% in self-esteem, 64,8% signs of anxiety and 49,6% depressive symptoms. In addition, 40% had systemic arterial hypertension. The clinical-epidemiological profile of women with invasive ductal breast carcinoma described is wide and has important sociodemographic components. Cancer treatment can trigger clinical changes relevant to the health, well-being and quality of life of these patients.
References
Akram, M., Iqbal, M., Daniyal, M. & Khan, A. U. (2017). Awareness and current knowledge of breast cancer. Biol Res, 50(1), 33.
Anampa, J., Makower, D. & Sparano, J. A. (2015). Progress in adjuvant chemotherapy for breast cancer: an overview. BMC Med, 17 (13), 195.
Arps, D. P., Healy, P., Zhao, L., Kleer, C. G. & Pang, J. C. (2013). Invasive ductal carcinoma with lobular features: a comparison study to invasive ductal and invasive lobular carcinomas of the breast. Breast Cancer Res Treat, 138(3), 719-26.
Bao, X., Sun, K., Tian, X., Yin, Q., Jin, M., Yu, N., Jiang, H., Zhang, J. & Hu, Y. (2018). Present and changing trends in surgical modalities and neoadjuvant chemotherapy administration for female breast cancer in Beijing, China: A 10-year (2006-2015) retrospective hospitalization summary report-based study. Thorac Cancer, 9(6), 707-717.
Cabral, A. L. L.V., Giatti, L., Casale, C. & Cherchiglia, M. L. (2019). Social vulnerability and breast cancer: differentials in the interval between diagnosis and treatment of women with different sociodemographic profiles. Cien Saude Colet, 24(2), 613-622.
Casasent, A. K., Schalck, A., Gao, R., Sei, E., Long, A., Pangburn, W., Casasent, T., Bernstam, M. F., Edgerton, M. E. & Navin, N. E. (2018). Multiclonal Invasion in Breast Tumors Identified by Topographic Single Cell Sequencing. Cell, 172(1-2), 205-217.
Cieślak, K. & Golusiński, W. (2018). Coping with loss of ability vs. emotional control and self-esteem in women after mastectomy. Rep Pract Oncol Radiothe, 23(3), 168-174.
Costa, W. A., Monteiro, M. N., Queiroz, J. F. & Gonçalves, A. K. (2017). Pain and quality of life in breast cancer patients. Clinics (Sao Paulo), 72(12), 758-763.
de Sanjose, S. & Tsu, V. D. (2019). Prevention of cervical and breast cancer mortality in low- and middle-income countries: a window of opportunity. Int J Womens Health, 11:381-386.
Dreyer, M. S., Nattinger, A. B., McGinley, E. L. & Pezzin, L. E. (2018). Socioeconomic status and breast cancer treatment. Breast Cancer Res Treat, 167(1), 1-8.
Early Breast Cancer Trialists' Collaborative Group (2002). Multi-agent chemotherapy for early breast cancer. Cochrane Database Syst Rev, (1), CD000487.
Ejlertsen, B. (2016) Adjuvant chemotherapy in early breast cancer. Dan Med J, 63(5), B5222.
Elshof, L. E., Schaapveld, M., Schmidt, M. K., Rutgers, E. J., Van, L. F. E. & Wesseling, J. (2016). Subsequent risk of ipsilateral and contralateral invasive breast cancer after treatment for ductal carcinoma in situ: incidence and the effect of radiotherapy in a population-based cohort of 10,090 women. Breast Cancer Res Treat, 159(3), 553-63.
Fennell, M. L., Das, I. P., Clauser, S., Petrelli, N. & Salner, A. (2010). The organization of multidisciplinary care teams: modeling internal and external influences on cancer care quality. J Natl Cancer Inst Monogr, 2010(40), 72-80.
Ghoncheh, M., Mirzaei, M, & Salehiniya, H. (2015). Incidence and Mortality of Breast Cancer and their Relationship with the Human Development Index (HDI) in the World in 2012. Asian Pac J Cancer Prev, 16(18), 8439-8443.
Gonçalves, C. V., Camargo, V. P., Cagol, J. M., Miranda, B. & Mendoza, R. A. S. (2017). O conhecimento de mulheres sobre os métodos para prevenção secundária do câncer de mama. Ciênc saúde coletiva, 22(12), 4073-4081.
Gonçalves, M. M., Guedes, N. A. B., Matos, S. S., Tiensoli, S. D., Simino, G. P. R. & Corrêa, A. R. (2018). Perfil dos Atendimentos a Pacientes Oncológicos em uma Unidade de Pronto Atendimento. Rev. enferm. Cent.-Oeste Min, 8, e2595.
Green, A. K., Aviki, E. M., Matsoukas, K., Patil, S., Korenstein, D. & Blinder, V. (2018). Racial disparities in chemotherapy administration for early-stage breast cancer: a systematic review and meta-analysis. Breast Cancer Res Treat, 172(2), 247-263.
Hahlweg, P., Didi, S., Kriston, L., Härter, M., Nestoriuc, Y. & Scholl, I. (2017). Process quality of decision-making in multidisciplinary cancer team meetings: a structured observational study. BMC Cancer, 17(1),772.
Han, H., Guo, W., Shi, W., Yu, Y., Zhang, Y., Ye, X. & He, J. (2017). Hypertension and breast cancer risk: a systematic review and meta-analysis. Sci Rep, 7:44877.
Haque, R., Prout, M., Geiger, A. M., Kamineni, A., Thwin, S. S. & Avila, C. (2014). Comorbidities and cardiovascular disease risk in older breast cancer survivors. Am J Manag Care, 20(1), 86-92.
Harris, L. N., Ismaila, N., McShane, L. M., Andre, F., Collyar, D. E., Gonzalez, A., Hammond, E. H., Kuderer, N. M., Liu, M. C., Mennel, R. G., Ponazak, C. V., Bast, R. C. & Hayes, D. F. (2016). Use of Biomarkers to Guide Decisions on Adjuvant Systemic Therapy for Women With Early-Stage Invasive Breast Cancer: American Society of Clinical Oncology Clinical Practice Guideline. J Clin Oncol, 34(10), 1134-50.
Hashmi, A. A., Aijaz, S., Mahboob, R., Khan, S. M., Irfan, M., Iftikhar, N., Nisar, M., Siddiqui, M., Edhi, M. M., Faridi, N. & Khan, A. (2018). Clinicopathologic features of invasive metaplastic and micropapillary breast carcinoma: comparison with invasive ductal carcinoma of breast. BMC Res Notes, 11(1), 531.
Hortobagyi, G. N., de la Garza, S. J., Pritchard, K., Amadori, D., Haidinger, R., Hudis, C.A., Khaled, H., Liu, M. C., Martin, M., Namer, M., O'Shaughnessy, J. A., Shen, Z. Z. & Albain, K. S. (2005). The global breast cancer burden: variations in epidemiology and survival. Clin Breast Cancer, 6(5), 391-401.
Imran, M., Al-Wassia, R., Alkhayyat, S. S., Baig, M. & Al-Saati, B. A. (2019). Assessment of quality of life (QoL) in breast cancer patients by using EORTC QLQ-C30 and BR-23 questionnaires: A tertiary care center survey in the western region of Saudi Arabia. PLoS One, 14(7), e0219093.
Kullberg, A., Sharp, L., Johansson, H. & Bergenmar, M. (2015). Information exchange in oncological inpatient care--patient satisfaction, participation, and safety. Eur J Oncol Nurs, 19(2), 142-147.
Lena, P. T., Rempel, C., Coltro, D., Frigeri, C. D. L. & Grave, M. T. Q. (2019). Perfil epidemiológico de mulheres mastectomizadas em um serviço de referência localizado no Vale do Taquari/RS. Rev epidemiol controle infecç, 9(2),122-128.
Li, C. I., Uribe, D. J. & Daling, J. R. (2005). Clinical characteristics of different histologic types of breast cancer. Br J Cancer, 31, 93(9), 1046-52.
Lôbo, J. L. S., Silva, M. L. C., Tomé, T. K. B. V. & de Souza, C. D. F. (2020). Mortalidade por Câncer de Mama Feminino em Alagoas no Período de 2001 a 2016: Análise de Tendência e Distribuição Espacial. Rev bras cancerol, 66(1), e-09656.
Magalhães, G., Brandão, S. C., Fustinoni, S. M., Matos, J. C. & Schirmer, J. (2017). Perfil clínico, sociodemográfico e epidemiológico da mulher com câncer de mama. J. res.: fundam. care. online, 9(2), 473-479.
Masood, S. (2016). Neoadjuvant chemotherapy in breast cancers. Women's Health (Lond), 12(5), 480-491.
Mathew, A., George, P. S., Ramadas, K., Mathew, B. S., Kumar, A., Roshni, S., Jayakumar, K. N. L & Booth, C. M. (2019). Sociodemographic Factors and Stage of Cancer at Diagnosis: A Population-Based Study in South India. J Glob Oncol. 5, 1-10.
Mehta, L. S., Watson, K. E., Barac, A., Beckie, T. M., Bittner, V., Cruz, S. F., Dent, S., Kondapalli, L., Ky, B., Okwuosa, T., Piña, L. I. & Volgman, A. S. (2018). Cardiovascular Disease and Breast Cancer: Where These Entities Intersect: A Scientific Statement From the American Heart Association. Circulation, 137(8), e30-e66.
Moo, T. A., Sanford, R., Dang, C. & Morrow, M. (2018). Overview of Breast Cancer Therapy. PET Clin, 13(3), 339-354.
Oliveira, V. A. S., Vilarinho, M. L. C. M. & Milanez, L. L. S. (2018). Characterization of women at risk of breast cancer at Primary Health Care. Rev Enferm UFPI, 7(1), 38-43.
Parise, C. & Caggiano, V. (2018). The influence of marital status and race/ethnicity on risk of mortality for triple negative breast cancer. PLoS One, 13(4).
Reinertsen, K. V., Cvancarova, M., Loge, J. H., Edvardsen, H., Wist, E. & Fosså, S. D. (2010). Predictors and course of chronic fatigue in long-term breast cancer survivors. J Cancer Surviv, 4(4), 405-14.
Reinertsen, K. V., Engebraaten, O., Loge, J. H., Cvancarova, M., Naume, B., Wist, E., Edvardsen, H., Wille, E., Bjøro, T. & Kiserud, C. E. (2017). Fatigue During and After Breast Cancer Therapy-A Prospective Study. J Pain Symptom Manage, 53(3), 551-560.
Rocha, F. S., Silva, W. S., Nascimento, E. R. & Bacciotti, A. M. (2018). Epidemiological profile of breast câncer in a reference hospital in the north region. Mastology, 28(3), 169-75.
Rogers, L. Q., Courneya, K. S., Anton, P. M., Verhulst, S., Vicari, S. K., Robbs, R. S. & McAuley, E. (2017). Effects of a multicomponent physical activity behavior change intervention on fatigue, anxiety, and depressive symptomatology in breast cancer survivors: randomized trial. Psychooncology, 26(11), 1901-1906.
Salvetti, M. G., Machado, C. S. P., Donato, S. C. T. & Silva, A. M. (2020). Prevalência de sintomas e qualidade de vida de pacientes com câncer. Rev bras enferm, 73(2), e20180287.
Santos, J. C. M., Silva, C. M., Teixeira, J. J. V. & Peder, L. D. (2019). Perfil epidemiológico e clínico de mulheres com câncer de mama na região oeste do Paraná. Rev bras ciênc saúde, 23(4), 449-458.
Souza, J. C. S. O., Nunes, A. S., Silva, J. L., Gonçalves, A. C. & Costa, S. C. V. (2018). Real-World Data Related to Non-Metastatic Breast Cancer in Young Women: Experience of a Single Institution. Rev bras cancerol, 64(1), 45-53.
Sun, Y. S., Zhao, Z., Yang, Z. N., Xu, F., Lu, H. J., Zhu, Z. Y., Shi, W., Jiang, J., Yao, P. P., & Zhu, H. P. (2017). Risk Factors and Preventions of Breast Cancer. Int J Biol Sci, 13(11), 1387–1397.
Telli, S. & Gürkan, A. (2019). Examination of Sexual Quality of Life and Dyadic Adjustment among Women with Mastectomy. Eur J Breast Health, 16(1), 48-54.
Tsaras, K., Papathanasiou, I. V., Mitsi, D., Veneti, A., Kelesi, M., Zyg, S. & Fradelos, E. C. (2018). Assessment of Depression and Anxiety in Breast Cancer Patients: Prevalence and Associated Factors. Asian Pac J Cancer Prev, 25.,19(6), 1661-1669.
van Hoeve J. C., Vernooij, R. W. M., Lawal, A. K., Fiander, M., Nieboer, P., Siesling, S. & Rotter, T. (2018). Effects of oncological care pathways in primary and secondary care on patient, professional, and health systems outcomes: protocol for a systematic review and meta-analysis. Syst Ver, 7(1), 49.
Vanni, G., Materazzo, M., Pellicciaro, M., Morando, L., Portarena, I., Anemona, L., D'Angelillo, M. R., Barbarino, R., Chiaravalloti, A., Meucci, R., Perretta, T., Deiana, C., Orsaria, P., Caspi, J., Pistolese, C. A. & Buonomo, O. C. (2020). Does Age Matter? Estimating Risks of Locoregional Recurrence After Breast-conservative Surgery. In Vivo, 34(3), 1125-1132.
Wang, L., Guyatt, G. H., Kennedy, S. A., Romerosa, B., Kwon, H. Y., Kaushal, A., Chang, Y., Craigie, S., de Almeida, C. P. B., Couban, R. J., Parascandalo, S. R., Izhar, Z., Reid, S., Khan, J. S., McGillion, M. & Busse, J. W. (2016). Predictors of persistent pain after breast cancer surgery: a systematic review and meta-analysis of observational studies. CMAJ, 188(14), E352-E361.
Weigelt, B., Geyer, F. C. & Reis, F. J. S. (2010). Histological types of breast cancer: how special are they? Mol Oncol, 4(3), 192-208.
Yedjou, C. G., Sims, J. N., Miele, L., Noubissi, L., Lowe, L., Fonseca, D. D., Alo, R. A., Payton, M. & Tchounwou, P. B. (2018). Health and Racial Disparity in Breast Cancer. Adv Exp Med Biol, 1152:31-49.
Yeo, S. K. & Guan, J. L. (2017). Breast Cancer: Multiple Subtypes within a Tumor? Trends Cancer, 3(11). 753-760.
Zhang, Y., Xu, H., Wang, T., He, J., Qiao, Y., Wei, J. & Dong, J. (2015). Psychosocial Predictors and Outcomes of Delayed Breast Reconstruction in Mastectomized Women in Mainland China: An Observational Study. PLoS One, 10(12), e0144410.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2021 Simone Yuriko Kameo; Ricardo Barbosa-Lima; Maria Júlia Oliveira Ramos; Tiago Vasconcelos Fonseca; Andressa Cabral Vassilievitch; Jéssica dos Santos Costa; José Cleyton de Oliveira Santos; Dayane Ketlyn da Cunha Santos; Bruno Ferreira Amorim; Pabliane Matias Lordelo Marinho; Namie Okino Sawada; Glebson Moura Silva
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
