Use of cyanoacrylate glue as an alternative in surgical procedures: an integrative review
DOI:
https://doi.org/10.33448/rsd-v10i2.12592Keywords:
Cyanoacrylates; Surgical procedures, Operative; Wound Healing; Sutures.Abstract
Objective: This article aims to verify whether the use of cyanoacrylate glue in surgical procedures produces beneficial outcomes for the patient regarding healing and cost benefit. Methods: An integrative literature review was performed in the PubMed, Bireme/BVS and SciELO databases, including articles referring to cyanoacrylates, surgeries and sutures in humans, published in Portuguese, English and Spanish. Literature review articles, dissertations, book chapters, case studies, and editorials were excluded. Results: A total of 897 articles were found, of which 830 were excluded after applying the inclusion and exclusion criteria, and after reading the abstracts and full texts. Thus, 67 articles were included in this review. Conclusion: Studies have shown that cyanoacrylate glues can be used as an alternative in surgical procedures, mainly due to their ease of application, decreased risk of contamination and increased healing efficiency. Although they do not replace sutures in all surgical procedures, cyanoacrylate glues are a fast, inexpensive and cost-effective method of healing, specifically in plastic, ophthalmic and cardiac surgeries.
References
Alemayehu, H., Sharp, N. E., Gonzalez, K., Poola, A. S., Snyder, C. L., & Peter, S. D. S. (2017). The role of 2-octyl cyanoacrylate in prevention of penile adhesions after circumcision: A prospective, randomized trial. Journal of pediatric surgery, 52(12), 1886-1890.
Ambriz-Gonzalez, G., Aguirre-Ramirez, P., García-de León, J. M., León-Frutos, F. J., Montero-Cruz, S. A., Trujillo, X., ... & Gonzalez-Ojeda, A. (2014). 2-octyl cyanoacrylate versus reintervention for closure of urethrocutaneous fistulae after urethroplasty for hypospadias: a randomized controlled trial. BMC urology, 14(1), 1-6.
Barbalinardo, R. J., Citrin, P., Franco, C. D., & Hobson II, R. W. (1986). A comparison of isobutyl 2-cyanoacrylate glue, fibrin adhesive, and oxidized regenerated cellulose for control of needle hole bleeding from polytetrafluoroethylene vascular prostheses. Journal of vascular surgery, 4(3), 220-223.
Carvalho, M. V. H. D., Marchi, E., & Lourenço, E. A. (2017). Comparison of arterial repair through the suture, suture with fibrin or cyanoacrylate adhesive in ex-vivo porcine aortic segment. Brazilian journal of cardiovascular surgery, 32(6), 487-491.
Covre, E. R., Melo, W. A. D., Tostes, M. F. D. P., & Fernandes, C. A. M. (2019). Permanência, custo e mortalidade relacionados às internações cirúrgicas pelo Sistema Único de Saúde. Revista Latino-Americana de Enfermagem, 27.
Daeschlein, G., Napp, M., Assadian, O., Bluhm, J., Krueger, C., von Podewils, S., ... & Kramer, A. (2014). Influence of preoperative skin sealing with cyanoacrylate on microbial contamination of surgical wounds following trauma surgery: a prospective, blinded, controlled observational study. International Journal of Infectious Diseases, 29, 274-278.
D'Assumpção, E. A. (2008). Cola de cianoacrilato de baixo custo em cirurgia plástica. Rev Soc Bras Cir Plast, 23(1), 22-5.
de Carvalho, M. V. H., & Marchi, E. (2013). Mecanismo de ação dos agentes hemostáticos locais e adesivos tissulares. Rev Med Minas Gerais, 23(4), 504-509.
Gorgulu, T., Olgun, A., Torun, M., & Kargi, E. (2016). A fast, easy circumcision procedure combining a CO2 laser and cyanoacrylate adhesive: a non-randomized comparative trial. International braz j urol, 42(1), 113-117.
Kim, H., Kim, W., Kang, G. H., Jang, Y. S., Choi, H. Y., Kim, J. G., ... & Kim, M. (2018). Comparison of Leukosan SkinLink with surgical suture for traumatic laceration repair: A randomized controlled trial. Medicine, 97(25).
Koonce, S. L., Eck, D. L., Shaddix, K. K., & Perdikis, G. (2015). A prospective randomized controlled trial comparing N-butyl-2 cyanoacrylate (Histoacryl), octyl cyanoacrylate (Dermabond), and subcuticular suture for closure of surgical incisions. Annals of plastic surgery, 74(1), 107-110.
Krishnamoorthy, B., Najam, O., Khan, U. A., Waterworth, P., Fildes, J. E., & Yonan, N. (2009). Randomized prospective study comparing conventional subcuticular skin closure with Dermabond skin glue after saphenous vein harvesting. The Annals of thoracic surgery, 88(5), 1445-1449.
Kusabara, A. A., & Kasahara, N. (2017). Managing glaucoma drainage device tube leak with cyanoacrylate. Acta ophthalmologica, 95(7), e662-e662.
Mikhail, A. E., Luquero, A. P., Pascual, J. F. R., & Gil, J. L. S. (2012). Fijación del material protésico en la hernioplastia inguinal abierta: sutura Vs. cola sintética. Cirugía Española, 90(7), 446-452.
Mobley, S. R., Hilinski, J., & Toriumi, D. M. (2002). Surgical tissue adhesives. Facial Plastic Surgery Clinics, 10(2), 147-154.
Oliveira, C. L. D., Santos, C. H. M. D., Bezerra, F. M. M., Bezerra, M. M., & Rodrigues, L. D. L. (2010). Utilização de adesivos de cianoacrilatos em suturas de pele. Revista Brasileira de Cirurgia Plástica, 25(3), 573-576.
Pereira, A. S., Shitsuka, D. M., Parreira, F. J., & Shitsuka, R. (2018). Metodologia da pesquisa científica. [e-book]. Santa Maria. Ed. UAB/NTE/UFSM. Recuperado de: https://repositorio.ufsm.br/bitstream/handle/1/15824/Lic_Computacao_Metodologia-Pesquisa-Cientifica.pdf?sequence=1.
Perry, A. W., & Sosin, M. (2009). Severe allergic reaction to Dermabond. Aesthetic surgery journal, 29(4), 314-316.
Shapiro, A. J., Dinsmore, R. C., & North Jr, J. H. (2001). Tensile strength of would closure with cyanoacrylate glue. The American Surgeon, 67(11), 1113.
Silva, L. S., Neto, J. B. F., & Santos, A. L. Q. (2007). Utilização de adesivos teciduais em cirurgias-Revisão. Bioscience Journal, 23(4).
Souza, S. C. D., & Briglia, C. H. (2011). Estudo comparativo entre etilcianoacrilato e sutura intradérmica no fechamento de excisões cutâneas. Revista Brasileira de Cirurgia Plástica, 26(4), 566-572.
Souza, S. C. D., & Briglia, C. H. (2010). Reparo de fissura de lóbulo auricular usando cola cirúrgica de menor custo. Revista Brasileira de Cirurgia Plástica, 25(4), 715-718.
Ueda, E. L., & Ottaiano, J. A. A. (2004). Comparação dos gastos com material para reparação de perfurações de córnea com cola de cianoacrilato e sutura de córnea. Arquivos Brasileiros de Oftalmologia, 67(1), 97-101.
Van Haute, C., Tailly, T., Klockaerts, K., & Ringoir, Y. (2015). Sutureless circumcision using 2-Octyl cyanoacrylate results in more rapid and less painful procedures with excellent cosmetic satisfaction. Journal of pediatric urology, 11(3), 147-e1.
Vargas, A., Foncea, C., & Campolo, A. (2017). Adhesivos de cianoacrilato en cirugía oral y maxilofacial. Revista clínica de periodoncia, implantologia y rehabilitación oral, 10(2), 107-110.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2021 José Marcos Valentim Filho; Lilamânie Tafnes Santos Pardinho; Katia de Miranda Avena; Victor Araújo Felzemburgh
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
