Development of the teeth, cervical vertebrae, hand and wrist combined for the estimation of the biological age
DOI:
https://doi.org/10.33448/rsd-v10i3.12948Keywords:
Age estimation; Biological age; Cervical vertebrae; Hand and wrist; Teeth.Abstract
This study aims to perform age estimation using three different parameters from dental and skeletal development. The sample consisted of 98 dental records of patients aged from 10 to 16 years old, containing the chronological age and a set of radiographs (panoramic, lateral cephalometric and carpal radiographs) taken in the same day. The biological age was assessed through the dental development from panoramic radiographs according to the Nicodemo's method. The stages of dental development were registered and imported in CRONOL software (UNESP, São Paulo, Brazil), which provided the estimated dental age. The lateral cephalometric radiographs were analyzed to assess the development of the vertebrae C2, C3 and C4. And carpal radiographs were evaluated according to Fishman's method. Shapiro-Wilk test was used to verify the normality of the chronological and estimated age. T-test for unpaired samples was used to compare the normal data. Chi-square test was used to analyze the age in function of sex. Moderate and strong correlations were found between the chronological and biological (estimated) ages for all the methods. Statistically significant differences between the development of males and females were not observed (p>0.05). A linear regression formula was designed to allow age estimates statistically more accurate (p<0.0001). The formula reached an accuracy rate of 71.4%. In general, the methods underestimated the age. The combination of methods led to optimal performances for age estimation. The performances were similar between males and females.
References
Alkhal, H. A., Wong, R. W. & Rabie, A. B. (2008). Correlation between chronological age, cervical vertebral maturation and Fishman's skeletal maturity indicators in southern Chinese. The Angle orthodontist, 78(4), 591–6.
Araújo, A. M. M., Pontual, M. L. A., França, K. P., Beltrão, R. V., & Pontual, A. A. (2010). Association between mineralization of third molars and chronological age in a Brazilian sample. Rev Odonto Ciênc, 25(4), 391-4.
Bagherpour, A., Pousti, M. & Adelianfar, E. (2014). Hand skeletal maturity and its correlation with mandibular dental development. J Clin Exp Dent, 6(3), e275-9.
Caldas, M. P., Ambrosano, G. M. B. & Haiter Neto, F. (2010). Computer-assisted analysis of cervical vertebral bone age using cephalometric radiographs in Brazilian subjects. Braz Oral Res, 24(1), 120–6.
Camacho-Basallo, P., Yáñez-Vico, R. M., Solano-Reina, E. & Iglesias-Linares, A. (2017). Five radiographic methods for assessing skeletal maturity in a Spanish population: is there a correlation? Acta Odontol Scand, 75(2), 106-12.
Cameriere, R., Flores-Mir, C., Mauricio, F. & Ferrante, L. (2007). Effects of nutrition on timing of mineralization in teeth in a Peruvian sample by the Cameriere and Demirjian methods. Ann Hum Biol, 34(5), 547-56.
Carneiro, A. P. C., Guimarães, J. A. T. L., Silva, R.M., Santiago, A. P. C. S. & Laureano Filho, J. R. (2010). Chronological table of third molar mineralization in a survey in the state of Alagoas, Brazil. Braz J Oral Sci, 9(4), 488-92.
Carvalho, A. C. A., Simões, C. C., Pinho, C., Freitas-Oliveira, L. S. A., Crusoé-Rebello, I. & Campos, P. S. F. (2010). Método de Análise da maturação óssea e estimativa de idade. Rev. Ciências Med. Biolog, 9(supl. 1), 95-103.
Damian, M. F., Woitchunas, F. E., Cericato, G. O., Cechinato, F., Moro, G., Massochin, M. E. & Castoldi, F. L. (2006). Análise da confiabilidade e da correlação de dois índices da maturação esquelética: índice carpal e índice vertebral. Rev Dental Press Ortodon Ortop Facial, 11(5), 110-2.
Duarte, H. E. M., Viek, R., Siqueira, D. F. & Sannomiya, E. K. (2008). Avaliação das idades dentária e óssea em indivíduos situados antes do surto do crescimento puberal. Ortodontia SPO, 41(2), 95-100.
Eklöf, O. & Ringertz, H. (1967). A method for assessment of skeletal maturity. Ann Radiol, 10, 330-6.
Eto, L. F. & Mazzieiro, E. T. (2005). Avaliação da correlação entre os estágios de mineralização dos dentes inferiores e a idade esquelética observados sob o gráfico de crescimento puberal. Rev Dent Press Ortodon Ortop Facial, 10(2), 75-86.
Fishman, L. S. (1982). Radiographic evaluation of skeletal maturation. A clinically oriented method based on hand-wrist films. Angle Orthod, 52(2), 88-112.
Franco, A., Vidigal, M. T. C., Oliveira, M. N., Nascimento, C. T. J. S., Silva, R. F. & Paranhos, L. R. (2020). Evidence-based mapping of third molar techniques for age estimation applied to Brazilian adolescents – a systematic review. Research, Society and Development, 9(10), e9339109395.
Grave, K. C. & Brown, T. (1976). Skeletal ossification and the adolescent growth spurt. Am J Orthod, 69, 611-9.
Graziosi, M. A. O. C., Nicodemo, R. A., Moraes, L. C. & Carvalho, I. M. M. (1999). Estudo radiográfico da cronologia de mineralização dentária, em portadores de fendas labiais e/ou palatinas - análise comparativa com a tabela da cronologia de mineralização dentária de Nicodemo, Moraes e Medici Filho. Braz Dent Sci, 2(1), 7-15.
Greulich, W. W. & Pyle, S.I. (1959). Radiographic atlas of skeletal development of the hand and wrist. Stanford University Press.
Gundim, A. C., Sousa, A. P., Silva, J. C., Oliveira, R., Yamamoto-Silva, F. P. & Silva, B. S. F. (2014). Third molars stage of mineralization and its relation to chronological age: Midwest Brazil sample. Rev Odontol UNESP, 43(5), 294-8.
Hassel, B. & Farm, A. G. (1995). Skeletal maturation evaluation using cervical vertebrae. Am J Orthod Dentofacial Orthop, 107(1), 58-66.
Karaday, B., Afsin, H., Ozaslan, A. & Karaday, S. (2014). Development of dental charts according to tooth development and eruption for Turkish children and Young adults. Imaging SciDent, 44(2), 103-13.
Khan, R. M. S. & Ijaz, A. (2011). Correlation of dental calcification and skeletal maturity indicators. Annals, 17(1), 22-6.
Kumar, S., Singla, A, Sharma, R., Virdi, M. S., Anupam, A. & Mittal, B. (2012). Skeletal maturation evaluation using mandibular second molar calcification stages. Angle Orthod, 82(3), 501-6.
Lamparski, D. G. (1972). Skeletal age assessment utilizing cervical vertebrae. Thesis (Master of Dental Science). University of Pittsburgh, Pittsburgh.
Lara, T. S., Bertoz, F. A., Santos, E. C. A. & Bertoz, A. P. M. (2008). Morfologia das terceiras e quartas vértebras cervicais representativas do surto de crescimento puberal. Rev Dental Press Ortodon Ortop Facial, 13(6), 66-76.
Lecca-Morales, R. M. & Carruitero, M. J. (2017). Relationship between dental calcification and skeletal maturation in a Peruvian sample. Dental Press J Orthod, 22(3), 89-96.
Maló, L., Lima, S., Teixeira, V., Canava, F. & Alves, S. (2014). Maturação esquelética numa população portuguesa – comparação entre maturação da mão e punho e vértebras cervicais. Rev Port Estomatol Med Dent Cir Maxilof, 55(2), 102-9.
Manhães Júnior, L. R. C. (2006). Correlação entre a maturação óssea das vértebras cervicais com a maturação óssea de mão e punho e com a mineralização dentária pelo método radiográfico. Tese (doutorado). Universidade Estadual Paulista, Faculdade de Odontologia, São José dos Campos.
Martins, J. C. R. & Sakima, T. (1977). Considerações sobre a previsão do surto de crescimento puberal. Ortodontia, 10(3), 164-70.
Mohammed, R. B., Kalyan, V. S., Tircouveluri, S., Vegesna, G. C., Chirla, A. & Varma, D. M. (2014). The reliability of Fishman method of skeletal maturation for age estimation in children of South Indian population. J Nat Sci Biol Med, 5(2), 297–302.
Molina, A., Bravo, M., Fonseca, G. M., Márquez-Grant, N. & Martín-de-Las-Heras, S. (2021). Dental age estimation based on pulp chamber/crown volume ratio measured on CBCT images in a Spanish population. International journal of legal medicine, 135(1), 359–364.
Moraes, S. H., Aragão, E. M. & Heck, A. R. (1998). Radiologia em endodontia. In: Berger, C R. (Coord.), Endodontia (pp.183-192). Pancast.
Moraes, M. E. L., Bastos, M. S., Santos, L.R.A., Castilho, J. C. M., Moraes, L. C. & Medici-Filho, E. (2007). Dental age in patients with Down syndrome. Braz Oral Res, 21(3), 259-64.
Moraes, M. E. L., Takeshita, W. M., Soares, M.G., Moraes, L. C. & Médice Filho, E. (2008). Apresentação do software Scpan para avaliação do Surto de Crescimento Puberal. Ortodontia SPO, 41(3), 179-83.
Moscatiello, V. A. M., Lederman, H., Moscatiello, R. A., Faltin Júnior, K. & Moscatiello, R. M. (2008). Cervical vertebral maturation and the correlation between the skeletal age of the hand-wrist as orthodontic treatment indicators. Rev Dent Press Ortodon Ortop Facial, 13(4), 92-100.
Nicodemo, R. A., Miranda, P. & Rangel, F. J. C. (1974). Freqüência de perdas dos primeiros molares permanentes entre Nísseis [Frequency of loss of Japanese first permanent molar teeth]. Rev Fac Odontol Sao Jose Dos Campos, 3(1), 73-7.
Pereira, A. S., Shitsuka, D. M., Parreira, F. J. & Shitsuka, R. (2018). Metodologia da pesquisa científica. UFSM.
Perinetti, G., Contardo, L., Gabrieli, P., Baccetti, T. & Di Lenarda, R. (2012). Diagnostic performance of dental maturity for identification of skeletal maturation phase. Eur J Orthod, 34(4), 487-92.
Pessamiglio, J. F. (2011). Estimativa de idade em crianças através da arcada dentária. Trabalho de Conclusão de Curso de Graduação. Universidade Federal do Rio Grande do Sul, Porto Alegre.
Pinchi, V., De Luca, F., Focardi, M., Pradella, F., Vitale, G., Ricciardi, F. & Norelli, G. A. (2016). Combining dental and skeletal evidence in age classification: pilot study in a sample of Italian sub-adults. Leg Med, 20, 75-79.
Pineau, J. C. (2020). Age Estimation of Teenage Boys During Puberty. The American journal of forensic medicine and pathology, 41(3), 188–193.
Sachan, K., Sharma, V.P. & Tandon, P. (2011). A correlative study of dental age and skeletal maturation. Indian J Dent Res, 22(6), 882.
San Román, P., Palma, J. C., Oteo, M. D. & Nevado, E. (2002). Skeletal maturation determined by cervical vertebrae development. European journal of orthodontics, 24(3), 303–311.
Santos, E. C. A., Bertoz, F. A., Arantes, F. M. & Reis, P. M. P. (2005). Avaliação da reprodutibilidade do método de determinação da maturação esquelética por meio de vértebras cervicais. Rev Dental Press Ortodon Ortop Facial, 10(2), 62-8.
Soegiharto, B. M., Cunningham, S. J. & Moles, D. R. (2008). Skeletal maturation in Indonesian and white children assessed with hand-wrist and cervical vertebrae methods. Am J Orthod Dentofacial Orthop, 134(2), 217-26.
Suma, G. N., Rao, B. B., Annigeri, R. G., Rao, D. J. K. & Goel, S. (2011). Radiographic correlation of dental and skeletal age: third molar, an age indicator. J Forensic Dent Sci, 3(1), 14-8.
Tanner, J. M. & Whitehouse, R. H. (1959). Standards for skeletal maturation. International Children’s Center.
Topolsik, F., Souza, R. B., Franco, A., Cuoghi, A. O., Assunção, L. R. S. & Fernandes, A. (2014). Dental development of children and adolescents with cleft lip and palate. Braz J Oral Sci, 13(4), 319-24.
Uysal, T., Ramoglu, S. I., Basciftci, F. A. & Sari, Z. (2006). Chronologic age and skeletal maturation of the cervical vertebrae and hand-wrist: is there a relationship? Am J Orthod Dentofacial Orthop, 130(5), 622-8.
Vieira, C. L., Oliveira, A. E. F., Ribeiro, C. C. C. & Lima, A.A.S.J. (2009). Relação entre os índices de maturação das vértebras cervicais e os estágios de calcificação dentária. Rev Press Ortodon Facial,14(2), 45-53.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2021 Marisa de Matos Ferraz Pêgo; Paola Fernanda Leal Corazza; Fernando Martins Baeder; Daniel Furtado Silva; Ana Carolina Lyra de Albuquerque; José Luiz Cintra Junqueira; Francine Kühl Panzarella
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.