The role of adipocyte in the inflammation and metabolism of the obese

Authors

DOI:

https://doi.org/10.33448/rsd-v10i9.18191

Keywords:

Inflammation; Metabolism; Adipocytes; Obesity.

Abstract

Objective: To investigate the role of adipocytes in inflammation caused by obesity. Methodology: This is an integrative review, carried out in the LILACS, SCIELO and MEDLINE / PUBMED databases, in the period from September 2020 to May 2021, in English, Spanish and Portuguese language, published between 2015 and May 2021. The following descriptors were used: inflammation, metabolism, adipocytes and obesity, as well as their English versions. Results: The inflammatory state produced by metabolic stress due to obesity is different from classical inflammation, the triggering factor is the excess of nutrients resulting from growth and increase in the number of adipocytes, making it a dysfunctional tissue. Metabolic complications in a state of obesity can be aggravated by an abnormal inflammatory response and it is known to be associated with the formation of toxic reactive oxygen species. Conclusion: It is concluded that adipocytes play an important role in the inflammation and metabolism of the obese, because through adipocytes the main pro-inflammatory cytokines are produced, which can lead to insulin resistance, hypertension, among other metabolic problems.

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Published

31/07/2021

How to Cite

SOUSA, E. F. G. de .; REIS , B. G. S. .; NUNES MENDES DE BRITO, A. . The role of adipocyte in the inflammation and metabolism of the obese. Research, Society and Development, [S. l.], v. 10, n. 9, p. e45810918191, 2021. DOI: 10.33448/rsd-v10i9.18191. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/18191. Acesso em: 23 nov. 2024.

Issue

Vol. 10 No. 9

Section

Review Article

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Copyright (c) 2021 Erica Fernanda Gomes de Sousa; Bruno Gabriel Santos Reis ; Andrea Nunes Mendes de Brito

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