Hematological and biochemical profile of female dogs with Cystic Endometrial Hyperplasia Complex - Pyometra submitted to treatment with Gentamicin Uterine Infusion
DOI:
https://doi.org/10.33448/rsd-v10i10.18762Keywords:
Pyometra; Aglepristone; Canine reproduction; Blood count.Abstract
The causes of pyometra are abnormal interactions between the uterus, circulating hormones and bacteria. Occurs in female dogs and cats. The use of contraceptives and undesirable mating can be predisposing factors. This disease is classified in two forms, the closed form is when the uterine cervix is occluded and presents an accumulation of infectious material, with an increase in uterine volume and a process of systemic intoxication. In the open form, there is expulsion of uterine secretion and milder clinical signs. The aim of this study was to report the treatment with the use of aglepristone and gentamicin in uterine infusion in two five-year-old pug dogs with pyometra. Two non-castrated bitches were treated at the Veterinary Hospital of a higher education institution, for presenting clinical signs compatible with pyometra. Assessments of hematological and biochemical parameters were performed. Where they were treated with the uterine lavage method with Gentamicin Uterine Infusion and Aglepristone. In the blood count exams of the animals reported, alterations were observed in the white series of both bitches, these alterations being called leukocytosis by neutrophil in animal one and leukocytosis by neutrophil and eosinophilia in animal two. At the end of the treatment, complete recovery of the animals to pyometra can be observed. The treatment performed proved to be satisfactory with the use of gentamicin in the uterine lavage method. The bitches in the study will resume their reproductive activities, and artificial insemination is indicated to prevent the recurrence of the pyometra.
References
Cabral, L. A. R. et al. (2016). Hemometra/Piometra em cadela: Tratamento clínico-cirúrgico. Relato de caso. Revista Brasileira de Higiene e Sanidade Animal, 10(3): 470-476.
Cruz-Pinto, C. E. et al. (2015). Casuistic analysis of surgical diseases in the small animal surgery sector of FMVZ-USP from 1988 to 2007. Brazilian Journal of Veterinary Research Animal Science, 52(1): 41–47.
Fenner W. R. (2003). Consulta Rápida em Clínica Veterinária. 3. ed. Rio de Janeiro: Guanabara Koogan.
Garcia Filho, S. P. et al. (2012). Piometra em Cadelas: Revisão de literatura. Revista científica eletrônica de medicina veterinária, 18: 1676-7353.
Garcia, C. Z., Nogueira, A. R. & Pinheiro Júnior, O. Á. (2009). Piometra aberta em cadela – Relato de caso. Revista científica eletrônica de medicina veterinária, n. 13.
Hagman, R., Kindahl, H. & Lagerstedt, A. S. (2006). Pyometra in bitches induces elevated plasma endotoxin and prostaglandin F2a metabolite levels. Acta Veterinaria Scandinavica, 47: 55-68. Disponível em <http://dx.doi.org/10.1186/1751-0147-47-55>.
Lopes, T. V. (2021). Tratamento terapêutico da piometra canina: um velho problema, uma nova abordagem. Tese de doutorado para obtenção do grau de Doutor em Ciência Animal pela Universidade Federal do Acre, UFAC. 92f. Rio Branco, Acre.
Lopes, T. V. et al. (2021). Perfil de sensibilidade antimicrobiana de bactérias isoladas, de piometra em cadelas, frente à infusão uterina de gentamicina (Gentrin®). Pesquisa, Sociedade e Desenvolvimento, [S. l.] 10(7): e26810715170, 2021. DOI: 10.33448 / rsd-v10i7.15170. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/15170. Acesso em: 21 jul. 2021.
Macente, B. I. Uso da Aglepristone no tratamento de piometra em cadela com gestação no estro subsequente. Revista Investigação Medicina Veterinária, 15(1): 46-48.
Marangon, W. F. et al. (2017). Piometra com Insuficiência Renal Aguda em Cadela – Relato de caso. Rev. Ciências Exatas e da Terra e Ciências Agrárias, (12)1: 14-20.
Nascimento, E. F. & Santos, R. L. (2011). Patologia da Reprodução dos Animais Domésticos. 3. ed. Rio de Janeiro: Guanabara Koogan, 2011.
Oliveira, K. S. (2007). Complexo Hiperplasia Endometrial Cística. Acta Scientiae Veterinariae, 35: 270-272.
Oliveira, R. G. et al. (2019). Piometra Em Cadela Com Complicação Renal. Ciência Animal, 29(1): 135-145.
Prasad, V. D., Kumar, P. R. & Sreenu, M. (2018). Pyometra in bitches: A review of literature. Res. Rev. J. Vet Sci. Technol, 1(6): 12–20.
Quartuccio, M. et al. (2020). Contrast-Enhanced Ultrasound in Cystic Endometrial Hyperplasia–Pyometra Complex in the Bitch: A Preliminary Study. Animals, 10(8): 1368.
RIBEIRO, L. S. (2019). Injúria Renal Aguda em cadelas com piometra: A importância do diagnóstico precoce. 53f. Dissertação (Mestrado em Ciência Animal) - Universidade Federal de Goiás, Escola de Veterinária e Zootecnia (EVZ), Programa de Pós-Graduação em Ciência Animal, Goiás.
Sant’anna, M. C. et al (2017). The importance of Gram-positive bacteria as the cause of canine pyometra. Semina: Ciências Agrárias, 38(2): 1077-1082.
Schweigert, A. et al (2009). Complexo Hiperplasia Endometrial Cística (Piometra) Em Cadelas – Diagnóstico E Terapêutica. Colloquium Agrariae, 5(1): 32–37.
Silva, V. B. (2018). Aspectos Clínicos e Tratamento em Cadelas Portadoras de Piometra. 2018. 23f. Trabalho de Conclusão de Curso - Universidade Federal Rural De Pernambuco, Recife.
Tilley, L. P. & Smith Júnior, F. W. K. (2008). Consulta Veterinária em 5 Minutos: Espécies Canina e Felina. 3. ed. São Paulo: Manole, 2008.
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Copyright (c) 2021 Thiago Vaz Lopes; João Gustavo da Silva Garcia de Souza; Agnis Genevi Moreira dos Santos; Emily Railda Tibúrcio Gonçalves Ferreira; Thaís de Almeida Souza; Igor Mansur Muniz; Sandro de Vargas Schons; Fernando Andrade Souza
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