Pregnant women with COVID- 19 and its consequences for newborns
DOI:
https://doi.org/10.33448/rsd-v10i12.20506Keywords:
Pregnancy; COVID -19; Newborn.; newbornAbstract
The COVID-19 pandemic, a respiratory disease caused by the coronavirus genus, raised questions regarding the risk classification of pregnant and postpartum women. Although the vast majority of the group remains asymptomatic or with classic symptoms of the disease (cough, fever, runny nose), the infection is related to an increase in adverse pregnancy events, such as pre-eclampsia and premature rupture of the placenta, in addition to increasing the chances of an intrauterine fetal death. This problem is reflected in newborns, which can be affected by maternal contamination, either because of the greater chances of prematurity or the risk of also being infected. Thus, the objective of this study is to evaluate in the literature the main consequences recorded by COVID-19 in newborns of mothers infected with the virus. For this, we searched for the descriptors in the platforms Google Scholar, LILACS, PubMED and SciELO, finding a total of 18736 articles. After applying the inclusion and exclusion criteria, 117 articles remained to be analyzed, of which 26 make up the current sample. Vertical transmission is still poorly reported, with the most common gestational manifestations forming pre-eclampsia, fetal distress and premature birth. In relation to newborns, most, when infected, do not present symptoms of the disease. Thus, it is concluded that further studies are needed to confirm the severity of COVID-19 in newborns of positive mothers, in order to improve the understanding of the needs and care of this group.
References
Amorim, M. M. R., Souza, A. S. R., Melo, A. S. D. O., Delgado, A. M., Florêncio, A. C. M. C. D. C., Oliveira, T. V. D., & Katz, L. (2021). COVID-19 e Gravidez. Revista Brasileira de Saúde Materno Infantil, 21, 337-353.
Barbero, P., Mugüerza, L., Herraiz, I., García Burguillo, A., San Juan, R., Forcén, L., & Galindo, A. (2020). SARS-CoV-2 in pregnancy: characteristics and outcomes of hospitalized and non-hospitalized women due to COVID-19. The Journal of Maternal-Fetal & Neonatal Medicine, 1-7.
Bentlin, M. R., de Almeida, M. F. B., Marba, S. T. M., Guinsburg, R., Rebello, C. M., de Siqueira Caldas, J. P., & do Nascimento, S. D. Coronavírus E Recém-Nascido: O Que Se Sabe Até O Momento? Versão 3.
Boaventura, M. D., Costa, M. R., Nunes, R. N., Santo Carine, C. S. C. S., Santos, S., Sampaio, I. L., & Moura, L. R. (2021). Covid-19 na gravidez, parto e pós-parto imediato: implicações e intercorrências. Brazilian Journal of Development, 7 (7), 73368-73382.
Brasil, Ministério da Saúde (2020). Recomendação nº 035 de 12 de maio de 2020.
Brito, S. B. P. et al. (2020). Mecanismos imunopatológicos envolvidos na infecção por SARS-CoV-2. Jornal Brasileiro de Patologia e Medicina Laboratorial, 56, e3352020, 2020.
Cardoso, P. C., Sousa, T. M. D., Rocha, D. D. S., Menezes, L. R. D. D., & Santos, L. C. D. (2021). A saúde materno-infantil no contexto da pandemia de COVID-19: evidências, recomendações e desafios. Revista Brasileira de Saúde Materno Infantil, 21, 213-220.
Carvalho, B. R. D., Adami, K. D. S., Gonçalves-Ferri, W. A., Samama, M., Ferriani, R. A., & Marcolin, A. C. (2021). COVID-19: Uncertainties from conception to birth. Revista Brasileira de Ginecologia e Obstetrícia, 43, 54-60.
Castro, P., Matos, A. P., Werner, H., Lopes, F. P., Tonni, G., & Araujo Júnior, E. (2020). Covid-19 and Pregnancy: An Overview. Revista Brasileira de Ginecologia e Obstetrícia, 42 (7), 420-426.
Chen, H., Guo, J., Wang, C., Luo, F., Yu, X., Zhang, W., & Zhang, Y. (2020). Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. The lancet, 395(10226), 809-815.
Chen, L., Li, Q., Zheng, D., Jiang, H., Wei, Y., Zou, L., & Qiao, J. (2020). Clinical characteristics of pregnant women with Covid-19 in Wuhan, China. New England Journal of Medicine, 382 (25), e100.
Crispim, M. E. S., Frade, A. C., de Vasconcellos, C. A. Neto, J. R. F., & de Brito, M. B. R. (2020). Infecção Por Covid-19 Durante A Gestação: Avaliação Das Manifestações Clínicas E Desfecho Gestacional. Revista de Ciências da Saúde Nova Esperança, 18 (3), 214-222.
Czeresnia, R. M., Trad, A. T. A., Britto, I. S. W., Negrini, R., Nomura, M. L., Pires, P., & Ruano, R. (2020). SARS-CoV-2 and Pregnancy: A Review of the Facts. Revista Brasileira de Ginecologia e Obstetrícia, 42 (9), 562-568.
de Albuquerque, L. P., Monte, A. V. L., & de Araújo, R. M. S. (2020). Implicações da COVID-19 para pacientes gestantes. Revista Eletrônica Acervo Saúde, 12 (10), e 4632-e 4632.
Deniz, M., & Tezer, H. (2020). Vertical transmission of SARS CoV-2: a systematic review. The Journal of Maternal-Fetal & Neonatal Medicine, 1-8.
dos Santos Guedes, B. L. C., do Nascimento, A. K. P., Melo, B. T. G., da Cunha, S. M. D. de Oliveira Filho, A. A., & de Oliveira, H. M. B. F. (2020). Aspectos gerais da COVID-19 na saúde de gestantes e recém-nascidos: Uma breve revisão. Research, Society and Development, 9 (7), e897974969-e897974969.
Dube, R., & Kar, S. S. (2020). COVID-19 in pregnancy: the fetal perspective—a systematic review. BMJ pediatrics open, 4 (1).
Elshafeey, F., Magdi, R., Hindi, N., Elshebiny, M., Farrag, N., Mahdy, S., & Nabhan, A. (2020). A systematic scoping review of COVID‐19 during pregnancy and childbirth. International Journal of Gynecology & Obstetrics, 150 (1), 47-52.
Estrela, C. (2018). Metodologia Científica: Ciência, Ensino, Pesquisa. Editora Artes Médicas.
Filho, E. B. S. et al. (2017). Infecção respiratória de importância clínica: uma revisão sistemática. Revista FIMCA, 4 (1), 7-16.
Godoi, A. P. N., Bernardes, G. C. S., S. Nogueira, L. S., Alpoim, P. N., & Pinheiro, M. D. B. (2021). Clinical Features and Maternal-fetal Results of Pregnant Women in COVID-19 Times. Revista Brasileira de Ginecologia e Obstetrícia, 43, 384-394.
Hcini, N. et al. (2020). Maternal, fetal and neonatal outcomes of large series of SARS-CoV-2 positive pregnancies in peripartum period: A single-center prospective comparative study. European Journal of Obstetrics, Gynecology and Reproductive Biology, 257, 11-18.
Karimi-Zarchi, M., Neamatzadeh, H., Dastgheib, S. A., Abbasi, H., Mirjalili, S. R., Behforouz, A., ... &Bahrami, R. (2020). Vertical transmission of coronavirus disease 19 (COVID-19) from infected pregnant mothers to neonates: a review. Fetal and pediatric pathology, 39 (3), 246-250.
Khan, S., Peng, L., Siddique, R., Nabi, G., Xue, M., Liu, J., & Han, G. (2020). Impact of COVID-19 infection on pregnancy outcomes and the risk of maternal-to-neonatal intrapartum transmission of COVID-19 during natural birth. Infection Control & Hospital Epidemiology, 41 (6), 748-750.
Lopes de Sousa, À. F., Carvalho, H. E. F. D'Oliveira, L. B. D. Schneider, G., Camargo, E. L. S., Watanabe, E., ... Fronteira, I. (2020). Effects of COVID-19 infection during pregnancy and neonatal prognosis: what is the evidence? International journal of environmental research and public health, 17 (11), 4176.
Macedo-Júnior, A. M. (2020). Covid-19: calamidade pública. Medicus, 2, (1), 1-6, 2020.
Procianoy, R. S., Silveira, R. C., Manzoni, P., &Sant'Anna, G. (2020). Neonatal COVID-19: little evidence and the need for more information. Jornal de pediatria, 96(3), 269-272.
Rondelli, G., Jardim, D., Hamad, G., Luna, E., Marinho, W., Mendes, L., & Gratão, L. (2020). Assistência às gestantes e recém-nascidos no contexto da infecção COVID-19: uma revisão sistemática. Desafios-Revista Interdisciplinar da Universidade Federal do Tocantins, 7 (Especial-3), 48-74.
Silva, F. L. et al. (2021). Gravidez, parto e puerpério na pandemia: os múltiplos sentidos do risco. Horizontes Antropológicos, 27, (59), 245-265, 2021.
Singh, V., Choudhary, A., Datta, M. R., & Ray, A. (2021). Maternal and Neonatal Outcomes of COVID-19 in Pregnancy: A Single-Centre Observational Study. Cureus, 13 (2).
Sociedade de Pediatria de São Paulo. (2020). Coronavírus e recém-nascido: o que se sabe até o momento?
Souza, H. C. C. et al. (2020) COVID-19 e gestação: manifestações clínicas, alterações laboratoriais e desfechos maternos, uma revisão sistemática de literatura. Brazilian Journal of Health Review, 3 (6), 15901-15918.
Stofel, N. S., Christinelli, D., Silva, R. C. D. S., Salim, N. R., Beleza, A. C. S., & Bussadori, J. C. D. C. (2021). Atenção perinatal na pandemia da COVID-19: análise de diretrizes e protocolos nacionais. Revista Brasileira de Saúde Materno Infantil, 21, 89-98.
Yang, Z., Wang, M., Zhu, Z., & Liu, Y. (2020). Coronavirus disease 2019 (COVID-19) and pregnancy: a systematic review. The Journalof Maternal-Fetal & Neonatal Medicine, 1-4.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2021 Ana Rafaela Labouré de Carvalho Vieira; Ana Júlia Carvalho Rocha; André Luiz Oliveira de Faria; Raphael Romanelli Andrade de Oliveira; Gérsika Bitencourt Santos Barros
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
