Intoxication of local anesthetics in dental practice: a literature review
DOI:
https://doi.org/10.33448/rsd-v10i16.23801Keywords:
Anesthesia; Local anesthetics; Intoxication.Abstract
Systemic intoxication of local anesthetics (LAs) is one of the most feared complications in anesthesia due to the risk for the cardiovascular system, for the central nervous system and, in particular, for triggering cardiorespiratory arrest, even in healthy patients. ALs interrupt nerve conduction, interfering with the function of all organs in which the conduction or transmission of nerve impulses occurs. One of the main factors involved is the rapid increase in plasma concentration. ALs in the constrictor vessels reduce poisoning by their slow absorption of anesthetic salt. In addition to providing anesthesia and/or analgesia for the patient, the dentist performing the procedure must always keep in mind that the prevention of these complications must always be observed. The aim of this article was to carry out a bibliographical survey on intoxication by local anesthetics, trying to emphasize the main symptoms, treatment and prevention. Bibliographic searches were performed in the SciELO, MEDLINE and PubMed databases, with articles published between 2010 and 2021.
References
Barbosa, B. A., Oliveira, L. K. R., Soares, M. F. M., Silva, T. O. S. S., Veloso, V. L., & Marques, R. B. (2012). Intoxicação com anestésicos locais: Revisão de Literatura. Revinter-revista intertox de toxicologia, risco ambiental e sociedade, 11(2), 5-12.
Barbosa, M. P. L., Boni, C. L. A., & Andrade, F. C. J. (2010). Conduta na intoxicação por anestésicos locais. Revista medica de minas gerais. 20(1) 24-30.
Carvalho, R. W. F., Pereira, C. U., Anjos, E. D., Filho, J. R. L., & Vasconcelos, B. C. E. (2010). Anestésicos locais: Como escolher e prevenir complicações sistêmicas. Revista portuguesa de estomatologia, medicina dentária e cirurgia maxilo facial, 51(2), 67-127.
Carvalho, B., Fritzen, E. L., & Parodes, A. G. (2013). O emprego dos anestésicos locais em Odontologia: Revisão de Literatura. Revista Brasileira 178 de Odontologia. 70(2), 178-81.
Dillane, D. & Finucane, B. T. (2010). Local anestheticsystemictoxicity La toxicitesyste mique desanesthe´siqueslocaux. Can J Anesth/J CanAnesth.
Edgcombe, H. & Hocking, G. (2015). Farmacologia dos anestésicos locais: Tutorial de anestesia da semana. John Radcliffe Hospital.
El-Boghdadly, Y. K., Pawa, A., & Chin, K. J. (2018). Local anestheticxsystemic: current perspectives. Dovcepress-local and regional anesthesia, 11. 35-44.
Franco, V. A. M. (2011). Toxicidade dos anestésicos locais. Universidade Braz Cubas. 18 de May.
Gonzalez, M. M., Timerman, S., & Oliveria, G. (2013). I Diretriz de Ressuscitação Cardiopulmonar e Cuidados Cardiovasculares de Emergência da Sociedade Brasileira de Cardiologia. Arq. Bras. Cardiol. 101(2).
Goyal, R. & Shukla, C. R. N. (2012). Local anestheticsystemictoxicity (LAST) e Shouldwenotbeconcerned? Medical Journalarmed forces índia. 68.
Linsey, E., Picard, J., & Weinberg, G. L. (2014). Local anaestheticsystemictoxicity. Oxford university, 15(3), 136-142.
Neto, E. M. R., Marques, L. A. R. V., Lotif, M. A. L., Lobo, P. L. D., Martiniano, C. R. Q., & Ferreira, M. A. D. (2014). Toxicidade de anestésicos locais na prática clínica. Revista eletrônica de farmácia,vol. XI, 47-59.
Oda, Y. (2019). Local anesthetic systemictoxicity: proposedmechanisms for lipidresuscitationandmethodsofprevention. Journal of anesthesia, 1-3.
Pinheiro, A. C., Marques, J. F., Vieira, M. S., & Almeida; L. S. B. (2015). Conhecimento de cirurgiões-dentistas sobre sinais e sintomas de toxicidade sistêmica associados ao uso de soluções anestésicas locais. RGO- revista gaúcha de odontologia, 63, 41-46.
Santos, F. C. (2012). Intoxicação anestésica: Causa, efeito e tratamento. Universidade estadual de londrina, 1-27.
Sekimoto, K., Tobe, M., & Saito, S. (2017). Localanesthetictoxicity: acuteandchronic management. Acute medicine e surgery, 4. 152
Teixeira, R. N. (2014). Anestesia Local sem Vasoconstritor versus com Vasoconstritor. Universidade Fernando Pessoa Faculdade de Ciências da Saúde. Porto.
Valencia, M. I. B. & Silva, J. F. V. (2013). Protocolo y necesidad de kit para toxicidad sistêmica por anestésicos locales. Revista colombiana de anestesiologia, 41(4), 274-279.
Yaddanapudi, S. (2011). Preventionof local anesthetic systemictoxicity. Journal of Anaesthesiology Clinical Pharmacology.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2021 Catarina Valéria Tavares de Oliveira Ferreira; João Batista de Vasconcelos; Ana Maria Guerra Costa
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.