Occurrence of infectious diseases during the first two years and symptoms of asthma in six-year-old children

Authors

DOI:

https://doi.org/10.33448/rsd-v11i2.25965

Keywords:

Asthma; Infectious diseases; Breast-feeding; Children.

Abstract

Objective: To observe possible association between the occurrence of infectious diseases during the first two years of life and the occurrence of asthma symptoms in six-year-old children. Methods: Cross-sectional study involving 956 six-year-old schoolchildren. Asthma symptoms were assessed through International Study of Asthma and Allergies in Childhood questionnaires. Socio-demographic data, mother-reported infectious diseases during the child's first two years of life, family history of asthma and breastfeeding were included. Multivariate analysis was performed with all significant variables and those with a p-value <0.20 using Poisson Regression with a robust estimator. Results: The reported wheezing or whistling in the chest in the past 12 months prevalence was 18.7%. There was found a 9% higher prevalence of asthma at six years of age in children who had had respiratory infections in the first two years of life. Children with a family history of asthma had a 7% higher and independent prevalence of asthma at six years of age and those breastfed presented 6% lower independent prevalence of asthma at six years of age. Conclusions: Higher prevalence of asthma reports at six years of age was found in children whose mothers reported infectious respiratory diseases during the first two years and with family history of asthma. Lower prevalence was observed in breastfed children in the first two years of life.

References

Asher, M. I., Keil, U., Anderson, H. R., Beasley, R., Crane, J., Martinez, F., Mitchell, E. A., Pearce, N., Sibbald, B. & Stewart, A. W. (1995). International Study of Asthma and Allergies in Childhood (ISAAC): rationale and methods. The European Respiratory Journal. 8(3):483-491. https://doi.org/10.1183/09031936.95.08030483.

Bacharier, L.B. (2014). Early-life weight gain, prematurity, and asthma development. The Journal of Allergy and Clinical Immunology. 133(5):1330-1331. https://doi.org/10.1016/j.jaci.2014.03.005.

Bonnelykke, K., Vissing, N. H., Sevelsted, A., Johnston, S. L. & Bisgaard H. (2015). Association between respiratory infections in early life and later asthma is independent of virus type. The Journal of Allergy and Clinical Immunology. 136(1):81-86. https://doi.org/10.1016/j.jaci.2015.02.024.

Beigelman, A. & Bacharier, L. B. (2016). Early-life respiratory infections and asthma development: role in disease pathogenesis and potential targets for disease prevention. Current Opinion in Allergy and Clinical Immunology. 16(2):172-178. https://doi.org/10.1097/aci.0000000000000244.

Casagrande, R. R. D., Pastorino, A. C., Souza, R. G. L., Leone, C., Sole, D. & Jacob, C. M. A. (2008). Prevalência de asma e fatores de risco em escolares da cidade de São Paulo. Revista de Saúde Pública. 42(3):517-523. https://doi.org/10.1590/S0034-89102008000300018.

Chatkin, M. N. & Menezes, A. M. B. (2005). Prevalência e fatores de risco para asma em escolares de uma coorte no Sul do Brasil. Jornal de Pediatria (Rio J). 81(5):411-416. https://doi.org/10.2223/JPED.1393.

Das, R. R. & Naik, S. S. (2015). Neonatal hyperbilirubinemia and childhood allergic diseases: a systematic review. Pediatric Allergy and Immunology. 26(1):2-11. https://doi.org/10.1111/pai.12281.

Friedman, N. J. & Zeiger, R. S. (2005). The role of breast-feeding in the development of allergies and asthma. The Journal of Allergy and Clinical Immunology. 115(6):1238-11248. https://doi.org/10.1016/j.jaci.2005.01.069.

Global Initiative for Asthma (2022). Global Strategy for Asthma Management and Prevention 2017. http://www.ginasthma.org/local/uploads/files/ GINA_Report_2015_Aug11.pdf.

Holt, P. G., Upham, J. W. & Sly, P. D. (2005). Contemporaneous maturation of immunologic and respiratory functions during early childhood: implications for development of asthma prevention strategies. The Journal of Allergy and Clinical Immunology. 116(1):16-24. https://doi.org/10.1016/j.jaci.2005.04.017.

Lai, C. K., Beasley, R., Crane, J., Foliaki, S., Shah, J & Weiland, S. (2009). Global variation in the prevalence and severity of asthma symptoms: phase three of the International Study of Asthma and Allergies in Childhood (ISAAC). Thorax. 64(6):476-483. https://doi.org/10.1136/thx.2008.106609.

Leal, V. N. C., Genov, I. R., Mallozi, M. C., Solé, D. & Pontillo, A. (2018). Polymorphisms in inflammasome genes and risk of asthma in Brazilian children. Molecular Immunology. 93:64-67. https://doi.org/10.1016/j.molimm.2017.11.006.

Litonjua, A. A., Carey, V. J. & Burge, H. A. (1998). Parental history and the risk for childhood asthma. Does mother confer more risk than father? American Journal of Respiratory and Critical Care Medicine. 158:176-81. https://doi.org/10.1164/ajrccm.158.1.9710014.

Lodge, C. J., Tan, D. J., Lau, M. X., Dai, X., Tham, R., Lowe, A. J., Bowatte, G., Allen, K. J. & Dharmage, S. C. (2015). Breastfeeding and asthma and allergies: a systematic review and meta-analysis. Acta Paediatrica. 104(467):38-53. https://doi.org/10.1111/apa.13132.

Lopes, G. P. ; Santos, R. D. C. Dos; Araújo, J. V. F. ; Medeiros, V. G. Da C. ; Mesquita, A. G. & Falcai, A. (2022). Associação entre vírus respiratórios e asma em crianças e adolescentes: uma revisão de escopo. Research, Society and Development, 11(1): e3511124297. https://doi.org/10.33448/rsd-v11i1.24297.

Mallol, J., Crane, J., von Mutius, E., Odhiambo, J., Keil, U. & Stewart A. (2013) The International Study of Asthma and Allergies in Childhood (ISAAC) phase three: a global synthesis. Allergologia et Immunopathologia. 41(2):73-85. https://doi.org/10.1016/j.aller.2012.03.001.

Oddy, W. H., Holt, P. G., Sly, P. D, Read, A. W., Landau, L. I., Stanley, F. J., Kendall, G. E. & Burton, P. R. (1999). Association between breast feeding and asthma in 6 year old children: findings of a prospective birth cohort study. British Medical Journal. 319(7213):815-819. https://doi.org/10.1136/bmj.319.7213.815.

Penders, J., Kummeling, I. & Thijs, C. (2011) Infant antibiotic use and wheeze and asthma risk: a systematic review and meta-analysis. The European Respiratory Journal. 38(2):295-302. https://doi.org/10.1183/09031936.00105010.

Perez-Losada, M., Castro-Nallar, E., Bendall. M. L., Freishtat, R. J & Crandall, K. A. (2015). Dual transcriptomic profiling of host and microbiota during health and disease in pediatric asthma. PloSOne. 1-17. https://doi.org/10.1371/journal.pone.0131819.

Rathinam, V. A. & Fitzgerald, K. A. (2016). Inflammasome complexes: emerging mechanisms and effector functions. Cell. 165(4), 792-800. https://doi.org/10.1016/j.cell.2016.03.046.

Rosa, A. M., Ignotti, E., Hacon, S. S. & Castro, H. A. (2009). Prevalência de asma em escolares e adolescentes em um município na região da Amazônia brasileira. Jornal Brasileiro de Pneumologia. 35(1): 7-13. https://doi.org/10.1590/S1806-37132009000100002.

Silva, D. R. N., Schneider, A. P. & Stein, R. T. (2009). O papel do aleitamento materno no desenvolvimento de alergias respiratórias. Scientia Medica. 19(1): 35-42.

Sociedade Brasileira de Pneumologia e Tisiologia (2012). Diretrizes da Sociedade Brasileira de Pneumologia e Tisiologia para o Manejo da Asma. Jornal Brasileiro de Pneumologia. 38(Sup 1).

Tanaka, K., Miyake, Y., Sasaki, S., Ohya, Y. & Hirota, Y. (2008). Maternal smoking and environmental tobacco smoke exposure and the risk of allergic diseases in Japanese infants: the Osaka Maternal and Child Health Study. The Journal of Asthma. 45(9):833-838. https://doi.org/10.1080/02770900802339742.

Tischer, C., Chen, C. M. & Heinrich J. (2011). Association between domestic mould and mould components, and asthma and allergy in children: a systematic review. The European Respiratory Journal. 38(4):812-824. https://doi.org/10.1183/09031936.00184010

Traebert, J., Lunardelli, S. E., Martins, L. G., Santos, K., Nunes, R. D., Lunardelli, A. N., Traebert, E. (2018) Methodological description and preliminary results of a cohort study on the influence of the first 1,000 days of life on the children’s future health. Anais da Academia Brasileira de Ciências. 90:3105-314. https://doi.org/10.1590/0001-3765201820170937.

Ullemar, V., Magnusson, P. K. E., Lundholm, C., Zettergren, A., Melén, E., Lichtenstein, P. & Almqvist, C. (2016). Heritability and confirmation of genetic association studies for childhood asthma in twins. Allergy. 2016; 71(2):230-8. https://doi.org/10.1111/all.12783.

Xu, X. F. & Du, L. Z. (2010). Epigenetics in neonatal diseases. The Journal of Chinese Medicine. 123(20):2948-2954.

Xu, X. F., Li, Y. J., Sheng, Y. J., Liu, J. L., Tang, L. F. & Chen, Z. M. (2014). Effect of low birth weight on childhood asthma: a meta-analysis. BMC Pediatrics. 14:275. https://doi.org/10.1186/1471-2431-14-275.

Wegienka, G., Zoratti, E. & Johnson, C.C. (2015). The role of the early-life environment in the development of allergic disease. Immunology and Allergy Clinics of North America. 35(1):1-17. https://doi.org/10.1016/j.iac.2014.09.002.

Wopereis, H., Oozeer, R., Knipping, K., Belzer, C. & Knol, J. (2014). The first thousand days - intestinal microbiology of early life: establishing a symbiosis. Pediatric Allergy and Immunology. 25(5):428-438. https://doi.org/10.1111/pai.12232.

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Published

01/02/2022

How to Cite

ANDRADE, J. F. de L.; TRAEBERT, E.; GARCIA, L. P.; TRAEBERT, J. Occurrence of infectious diseases during the first two years and symptoms of asthma in six-year-old children. Research, Society and Development, [S. l.], v. 11, n. 2, p. e47011225965, 2022. DOI: 10.33448/rsd-v11i2.25965. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/25965. Acesso em: 22 nov. 2024.

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Health Sciences