Palliative care and bone marrow transplantation: an integrative literature review

Authors

DOI:

https://doi.org/10.33448/rsd-v11i10.32837

Keywords:

Palliative care; Bone marrow transplant; Literature review as topic.

Abstract

Introduction: Bone Marrow Transplantation (BMT) is a treatment with important curative potential, which raises great hope in patients experiencing diseases that pose a serious threat to the continuity of life. However, such treatment is permeated by high risks, in addition to the possibility of relapse of the disease still existing after it, thus, it is important to consider care approaches that cover this unpredictability, such as Palliative Care. Objective: To describe the contributions of the palliative care approach in bone marrow transplantation, which is characterized as a treatment with a curative proposal for patients with diseases that pose a serious threat to the continuity of life. Method: Integrative Literature Review carried out in the Scopus, PubMed, PsychINFO and LILACS databases, covering studies from 2011 to 2021. The studies were categorized based on content analysis. Results: After applying the exclusion criteria, six studies remained that made up the corpus of this work. Results showed that the early integration of palliative care into standard BMT care significantly contributes to the management of physical and emotional symptoms, exploration of topics not addressed by other professionals, such as coping with the moment, as well as discussions about advance care planning. Conclusion: Palliative Care adds numerous gains in relation to the care of the patient undergoing BMT. However, there is a scarcity of studies involving both themes and the need to develop new studies that can promote this practice within BMT clinics.

References

Anders, J. C., Soler, V. M., Brandão, E. M., Vendramini, E. C., Bertagnolli, C. L. S., Giovani, P. G., Carvalho, E. C., Suen, V. M. M., Marchini, J. S. & Voltarelli, J. C. (2000). Aspectos de enfermagem, nutrição, fisioterapia e serviço social no transplante de medula óssea. Revista Medicina (Ribeirão Preto Online). 33(4):463-485.

Beattie, S., Lebel, S., Petricone-Westwood, D., Wilson, K. G., Harris, C., Devins, G., Huebsch, L. & Tay, J. (2016). Balancing give and take between patients and their spousal caregivers in hematopoietic stem cell transplantation. Psychooncology. 26(12):2224–31. http://dx.doi.org/10.1002/pon.4340.

Cezar, V. S., Waterkemper, R., Rabin, E. G., Castilho, R. K. & Reys, K. Z. (2019). Continuous education in palliative care: an action research proposal. RPCFO. 11(2):324–32. https://doi.org/10.9789/2175-5361.2019.v11i2.324-332

Coenson, C. & Dimsdale, J. E. (1994). Psychiatric liaison on a bone marrow transplantation unit. Gen Hosp Psychiatry. 16(2):131–4. http://dx.doi.org/10.1016/0163-8343(94)90057-4

Contel, J. O. B., Sponholz, Jr. A., Torrano-Masetti, L. M., Almeida, A. C., Oliveira, E. A., Jesus, J. S., Santos, M. A., Loureiro, S. R. & Voltarlli, J. C. (2000). Aspectos psicológicos e psiquiátricos do transplante de medula óssea. Revista Medicina (Ribeirão Preto Online). 33(3):294.

El-Jawahri, A., Traeger, L. Greer, J. A., Van Dusen, H., Fishman, S. R., LeBlanc, T. W., Pirl, W. F., Jackson, V. A., Telles, J., Rhodes, A., Li, Z., Spitzer, T. R., McAfee, S., Chen, Y. B. A. & Temel, J. S. (2017). Effect of inpatient palliative care during hematopoietic stem-cell transplant on psychological distress 6 months after transplant: results of a randomized clinical trial. J Clin Oncol. 35(32):3714–21. http://dx.doi.org/10.1200/JCO.2017.73.2800

Ganong, L. H. (1987). Integrative reviews of nursing research. Res Nurs Health. 10(1):1–11. http://dx.doi.org/ 10.1002/nur.4770100103

Gomes, A. L. Z. & Othero, M. B. (2016). Cuidados paliativos. Estud Avancados. 30(88):155–66. https://doi.org/10.1590/S0103-40142016.30880011

Harden, K. L. & Schembri, J. A. (2016). Early Intervention With Transplantation Recipients to Improve Access to and Knowledge of Palliative Care. Clinical Journal of Oncology Nursing, Michigan. 20(4):88-92. https://doi.org/10.1188/16.CJON.E88-E92

Hui, D., Didwaniya, N., Vidal, M., Shin, S. H., Chisholm, G., Roquemore, J. & Bruera, E. (2014). Quality of end-of-life care in patients with hematologic malignancies: a retrospective cohort study. Cancer. 120(10):1572–8. https://doi.org/10.1002/cncr.28614

Lafond, D. A., Kelly, K. P., Hinds, P. S., Sill, A. & Michael, M. (2015). Establishing feasibility of early palliative care consultation in pediatric hematopoietic stem cell transplantation. J Pediatr Oncol Nurs. 32(5):265–77. https://doi.org/10.1177/1043454214563411.

LeBlanc, T. W., Roeland, E. J. & El-Jawahri, A. (2017). Early palliative care for patients with hematologic malignancies: is it really so difficult to achieve? Curr Hematol Malig Rep. 12(4):300–8. https://doi.org/10.1007/s11899-017-0392-z

Loggers, E. T., LeBlanc, T. W., El-Jawahri, A., Fihn, J., Bumpus, M. & David, J. (2016). Pretransplantation supportive and palliative care consultation for high-risk hematopoietic cell transplantation patients. Biol Blood Marrow Transplant. 22(7):1299–305. http://dx.doi.org/10.1016/j.bbmt.2016.03.006

Mendes, K. D. S., Silveira, R. C. C. P. & Galvão, C. M. (2008). Revisão integrativa: método de pesquisa para a incorporação de evidências na saúde e na enfermagem. Texto Context – Enferm. 17(4):758–64.

Minayo, M. C. S. & Gomes, R. (2008). O desafio da pesquisa social. In: Minayo, M. C. S.; Deslandes, S. F.; Gomes, R. (Eds.), Pesquisa social: teoria, método e criatividade. 27a ed. Petrópolis: Vozes, 9–29.

Needle, J. S., Peden-McAlpine, C., Liaschenko, J., Koschmann, K., Sanders, N., Smith A., Schellinger, S. E. & Lyon, M. E. (2020). “Can you tell me why you made that choice?”: a qualitative study of the influences on treatment decisions in advance care planning among adolescents and young adults undergoing bone marrow transplant. Palliat Med. 34(3):281–90. https://doi.org/10.1177/0269216319883977

Nelson, A. M., Johnson, P. C., Kavanaugh, A. R., Jackson, V. A., Jagielo, A. D., Fenech, A. L., Reynolds, M. J., Topo, C., Yi, A. M., Horick. N., Temel, J. S., Greer, J. A. & Jawahri, A. E. (2021). Palliative care for patients undergoing stem cell transplant: intervention components and supportive care measures. Bone Marrow Transplant [Internet]. 56(8):1971–7. http://dx.doi.org/10.1038/s41409-021-01281-2

Oliveira-Cardoso, E. A., Mastropietro, A. P., Voltarelli, J. C. & Santos, M. A. (2009). Qualidade de vida de sobreviventes do transplante de medula óssea (TMO): um estudo prospectivo. Rev Eletrônica Enferm. 25(01):621–8.

Ortega, E. T. T., Kojo, T. K., Lima, D. H., Veran, M. P. & Neves, M. I. (2004). Compêndio de enfermagem em transplante de células-tronco hematopoéticas: rotinas e procedimentos em cuidados essenciais e em complicações. Editora Maio.

Palomeni, A., Moreno, E. & Schulz-Kindermann, F. Psychology Morbidity (2019). In: Carreara E, Dufuour C, Mohty M, Kröger N, editors. The EBMT Handbook - Hematopoietic Stem Cell Transplantation and Cellular Therapies. (7a ed.) Springer Link.

Pereira, D. R. & Cortez, E. A. (2014). Sofrimento psíquico na equipe de transplante de medula óssea - uma revisão integrativa. Revista Medicina (Ribeirão Preto). 47(2):104-111. http://dx.doi.org/10.11606/issn.2176-7262.v47i2p104-111

Reine, P. S. K. (2020). Quando o TCTH é necessário: repercussões psicológicas diante do impacto desta “nova” proposta de tratamento. In: n: Baptista, C. H. V. (ed). Psicologia e Psico-Oncologia em Transplante de Medula Óssea. Editora Maker Mídea. 61–74.

Ruiz, M., Reynolds, P., Marranzini, R., Khan, A., Ketterer, J. & Brahim, A. (2018). Role of early palliative care interventions in hematological malignancies and bone marrow transplant patients: barriers and potential solutions. Am J Hosp Palliat Med. 35(11):1456–60. http://dx.doi.org/10.1177/1049909118772849.

Sánchez, A. F., Armesto, A. M. F., Chávez, C. B. & Ruiz, M. (2020). Revisiting early palliative care for patients with hematologic malignancies and bone marrow transplant: why the delay? Cureus. 12(9):1–11. http://dx.doi.org/10.7759/cureus.10504

Silva, B. C. A., Santos, M. A. & Oliveira-Cardoso, E. A. (2019). Vivências de familiares de pacientes com câncer: revisitando a literatura. Rev da SPAGESP. 20(1):140–53. http://pepsic.bvsalud.org/pdf/rspagesp/v20n1/v20n1a11.pdf

Simpson, E. & Dazzi, F. (2019) Bone marrow transplantation 1957-2019. Front Immunol. 5(10):1246. http://dx.doi.org/10.3389/fimmu.2019.01246

Selvaggi, K. J., Vick, J. B., Jessell, S. A., Lister, J., Abrahm, J. L. & Bernacki, R. (2014). Bridging the gap: a palliative care consultation service in a hematological malignancy-bone marrow transplant unit. J Community Support Oncol. 12(2):50–5. http://dx.doi.org/10.12788/jcso.0015.

Sousa, L. M. M., Marques-Vieira, C., Severino, S. & Antunes, V. (2017). A metodologia da revisão integrativa da literatura em enfermagem. Rev Investig em Enferm. 21(2):17–26.

Suthumphong, C., Tran, D. B. & Ruiz, M. (2021). Perceptions and misperceptions of early palliative care interventions for patients with hematologic malignancies undergoing bone marrow transplantation. Cureus. 13(3):10–4. http://dx.doi.org/10.7759/cureus.13876.

Teodoro, J. L. (2020). O que o psicólogo precisa saber sobre o TCTH? In: Baptista, C. H. V. (ed). Psicologia e Psico-Oncologia em Transplante de Medula Óssea. Editora Maker Mídea,.31-40.

Tierney, D. K., Passaglia, J. & Jenkins, P. (2014). Palliative care of hematopoietic cell transplant recipients and families. Semin Oncol Nurs. 30(4):253–61. http://dx.doi.org/10.1016/j.soncn.2014.08.007

World Health Organization (2002). Definition of palliative care. Genebra. Recuperado de: https://www.who.int/health-topics/palliative-care

World Health Organization (2007). Palliative Care. Cancer control: knowledge into action: WHO guide for effective programs. Genebra. https://pubmed.ncbi.nlm.nih.gov/24716262/

Published

28/07/2022

How to Cite

VENDRAMINI, D. M.; OLIVEIRA-CARDOSO, Érika A. de . Palliative care and bone marrow transplantation: an integrative literature review. Research, Society and Development, [S. l.], v. 11, n. 10, p. e215111032837, 2022. DOI: 10.33448/rsd-v11i10.32837. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/32837. Acesso em: 23 apr. 2024.

Issue

Section

Human and Social Sciences