The importance of clinical pharmaceuticals in pandemic times related to drug interactions in Açailândia-MA
DOI:
https://doi.org/10.33448/rsd-v11i15.34299Keywords:
Pharmaceutical; COVID-19; Drug interaction.Abstract
Given that the COVID-19 pandemic has brought about a major problem in world health, it has led to a greater performance of health professionals, including pharmacists, due to the high demand in the provision of health services in an individualized and collective way in pharmacotherapy and health education. SARS-CoV-2 is contagious, manifesting itself in a severe acute form, characterized as severe acute respiratory syndrome (ARDS), where symptoms are similar to other viral infections, with variability of transmissibility from individual to individual. Research is carried out on drug interactions during the pandemic in Açailândia-MA, in order to point out the importance of the clinical pharmacist during the pandemic scenario. Therefore, it is necessary to analyze the drug interactions that are recurrent in the treatment of COVID-19 and compile the problem of self-medication during the pandemic. Field research is carried out using medical prescriptions. In view of this, it appears that the results presented from 248 medical prescriptions result in antimicrobials (n=280), antiparasitics (n=138) and vitamins (n=128) prescribed, observing their interactions by severity, highlighting moderate in 96, 3% in higher percentage. What imposes the observation is that the pharmacist becomes the essential professional in the quality of life of the patient, being able to optimize the pharmacological treatment and improve health and adherence to pharmacotherapy.
References
Albuquerque Junior, L. A. B., et al. Importância da farmácia clínica para a identificação e resolução de problemas relacionados a medicamentos (PRM). Saúde em Foco, 13(2),
Barlow, A., Landolf, K. M., Barlow, B., Yeung, S. Y. A., Heavner, J. J., Claassen, C. W., & Heavner, M. S. (2020). Review of emerging pharmacotherapy for the treatment of coronavirus disease 2019. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 40(5), 416-437.
Batista, S. D. C. M., Albuquerque, L. E. R., da Silva, N. M., dos Santos, B. G. C., & dos Santos Medeiros, J. (2020). Polimedicação, atenção farmacêutica e cuidado farmacêutico. Journal of Biology & Pharmacy and Agricultural Management, 16(4).
Bourgonje, A. R., Abdulle, A. E., Timens, W., Hillebrands, J. L., Navis, G. J., Gordijn, S. J., & van Goor, H. (2020). Angiotensin‐converting enzyme 2 (ACE2), SARS‐CoV‐2 and the pathophysiology of coronavirus disease 2019 (COVID‐19). The Journal of pathology, 251(3), 228-248.
Cheng, H., Wang, Y., & Wang, G. Q. (2020). Organ‐protective effect of angiotensin‐converting enzyme 2 and its effect on the prognosis of COVID‐19. Journal of medical virology, 92(7), 726-730.
de Freitas Mussi, R. F., Mussi, L. M. P. T., Assunção, E. T. C., & Nunes, C. P. (2019). Pesquisa Quantitativa e/ou Qualitativa: distanciamentos, aproximações e possibilidades. Revista Sustinere, 7(2), 414-430.
Esher, A., & Coutinho, T. (2017). Uso racional de medicamentos, farmaceuticalização e usos do metilfenidato. Ciência & Saúde Coletiva, 22, 2571-2580.
Gomes, V. P., Silva, M. T., & Galvão, T. F. (2017). Prevalência do consumo de medicamentos em adultos brasileiros: uma revisão sistemática. Ciência & Saúde Coletiva, 22, 2615-2626.
Guo, Y. R., Cao, Q. D., Hong, Z. S., Tan, Y. Y., Chen, S. D., Jin, H. J., & Yan, Y. (2020). The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak–an update on the status. Military medical research, 7(1), 1-10.
Guruprasad, L. (2021). Human coronavirus spike protein-host receptor recognition. Progress in biophysics and molecular biology, 161, 39-53.
Hasöksüz, M., Kilic, S., & Saraç, F. (2020). Coronaviruses and sars-cov-2. Turkish journal of medical sciences, 50(9), 549-556.
Li, H., Zheng, S., Liu, F., Liu, W., & Zhao, R. (2021). Fighting against COVID-19: innovative strategies for clinical pharmacists. Research in Social and Administrative Pharmacy, 17(1), 1813-1818.
Meftahi, G. H., Jangravi, Z., Sahraei, H., & Bahari, Z. (2020). The possible pathophysiology mechanism of cytokine storm in elderly adults with COVID-19 infection: the contribution of “inflame-aging”. Inflammation Research, 69(9), 825-839.
Molloy, E. J., & Bearer, C. F. (2020). COVID-19 in children and altered inflammatory responses. Pediatric research, 88(3), 340-341.
Nunes, G. C., Nascimento, M. C. D., & de Alencar, M. A. C. (2016). Pesquisa científica: conceitos básicos. ID on line. Revista de psicologia, 10(29), 144-151.
Paumgartten, F. J. R., & Oliveira, A. C. A. X. D. (2020). Off label, compassionate and irrational use of medicines in Covid-19 pandemic, health consequences and ethical issues. Ciencia & saude coletiva, 25, 3413-3419.
Stratton, C. W., Tang, Y. W., & Lu, H. (2021). Pathogenesis‐directed therapy of 2019 novel coronavirus disease. Journal of medical virology, 93(3), 1320-1342.
Sun, D., Li, H., Lu, X. X., Xiao, H., Ren, J., Zhang, F. R., & Liu, Z. S. (2020). Clinical features of severe pediatric patients with coronavirus disease 2019 in Wuhan: a single center’s observational study. World Journal of Pediatrics, 16(3), 251-259.
Tafler, L., Danilevsky, A., & Seth, D. (2021). Azithromycin in the Successful Management of COVID-19: A Family Physician’s Perspective. Cureus, 13(4).
Umakanthan, S., Sahu, P., Ranade, A. V., Bukelo, M. M., Rao, J. S., Abrahao-Machado, L. F., & Dhananjaya, K. V. (2020). Origin, transmission, diagnosis and management of coronavirus disease 2019 (COVID-19). Postgraduate medical journal, 96(1142), 753-758.
Wishart, D. S., Feunang, Y. D., Guo, A. C., Lo, E. J., Marcu, A., Grant, J. R., & Wilson, M. (2018). DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic acids research, 46(D1), D1074-D1082.
Y Yavuz, S., & Ünal, S. (2020). Antiviral treatment of COVID-19. Turkish journal of medical sciences, 50(9), 611-619.
Yuan, H. W., & Wen, H. L. (2021). Research progress on coronavirus S proteins and their receptors. Archives of Virology, 166(7), 1811-1817.
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Copyright (c) 2022 Nayranna Chrystina Sobrinho Costa de Sousa; Vinycius Manoel Sobrinho Costa de Sousa; Francisco Alves Lima Junior ; Patrícia dos Santos Silva Queiroz; Karla Vanessa Morais Lima; Flávio Silva de Carvalho; Enderson Sousa Fernandes; Benedita Maryjose Gleyk Gomes; Caroline Amélia Gonçalves; Antonio Silva Machado
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